Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P21817 (RyR1)
 1,154 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
RyR1 1154
ryanodine receptor 417
RyR2 213
RyR3 132
RYR1 124
dihydropyridine receptor 106
calmodulin 79
Sep 76
Mol 74
cardiac muscle 69
endoplasmic reticulum 68
FKBP12 63
ATP 55
calcineurin 47
FK506 42
DHPR 35
ATPase 33
calcium channel 28
triadin 24
SERCA1 22
more...
Disease
malignant hyperthermia 172
myopathy 77
heart failure 31
Central core disease 26
cancer 26
hypertension 14
diabetes 12
tumor 11
depression 10
cold 9
centronuclear myopathy 9
DM1 8
multicore 7
SDS 6
stroke 6
GSH 6
scoliosis 6
aggression 6
myocardial infarction 5
prolapse 5
more...
Symptom
weakness 57
anesthesia 22
fatigue 19
ophthalmoplegia 14
hypotonia 13
pain 7
muscle rigidity 4
cachexia 3
exhaustion 3
myalgia 3
seizures 2
low back pain 2
respiratory distress 2
photophobia 2
dyspnea 2
muscle stiffness 2
hypothermia 2
collapse 2
starvation 1
overweight 1
more...
Drug
caffeine 164
Cardiovasc 9
Vitamin A 7
DM1 5
ROS 5
Asn 5
PCP 3
lysine 3
CPM 3
K201 3
CaCl2 2
Triclosan 2
PCB 2
Alanine 2
Spectrum 2
ABC 2
RFP 2
all-trans-retinol 2
CaCl2 2
CaCl2 2
more...
Enzyme
dihydropteridine reductase 35
ATPase 33
protein kinase 21
calcineurin 15
glutathione S-transferase 14
protein kinase C 6
PARP 6
creatine kinase 5
trypsin 5
AMPK 4
renin 4
cathepsin L 4
RNase 3
caspase-3 3
phospholipase C 3
RNase 3
calcium pump 3
PCP 3
endonuclease 3
mitogen-activated protein kinase 3
more...
Compound
calcium 496
caffeine 164
Ryanodine 102
Dec 83
DNA 71
ATP 55
oxygen 52
FK506 42
m-cresol 29
Mg2+ 27
cysteine 24
alanine 21
arginine 19
Clin 18
sodium 18
Dantrolene 18
water 15
threonine 14
nitric oxide 13
lysine 12
more...