Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P21817 (RyR1)
 1,154 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
RyR1 1154
ryanodine receptor 417
RyR2 213
RyR3 132
RYR1 124
dihydropyridine receptor 106
calmodulin 79
Sep 76
Mol 74
cardiac muscle 69
endoplasmic reticulum 68
FKBP12 63
ATP 55
calcineurin 47
FK506 42
DHPR 35
ATPase 33
calcium channel 28
triadin 24
SERCA1 22
Gen 20
FK506-binding protein 18
HEK 16
fused 16
IP3R 15
FKBP 14
microsomal 13
PKA 12
NMR 12
STIM1 10
L-type calcium channel 10
CACNA1S 10
Cav1.1 10
junctin 10
S100A1 9
AMP 9
RYR2 8
phosphatase 8
muscle specific 8
non-muscle 8
calpain 8
RAD51 7
SERCA2 7
ASI 7
insulin 7
NER 7
IP3R1 7
BRCA1 6
glutathione S-transferase 6
GST 6
SDS 6
polypeptide 6
MRI 6
MTM1 6
prolyl isomerase 6
TRPC3 6
GSH 6
myotubularin 6
SPRY2 6
glutathione transferase 6
SEPN1 6
IP3R2 5
TRPC1 5
Triadin 5
PARP 5
ROS 5
CRAC 5
BRCA2 5
dystrophin 5
STAC3 5
TOF 5
myosin heavy chain 5
CCD 5
DM1 5
NOX4 5
caspase-3 5
Ca2+-ATPase 5
phospholamban 5
creatine kinase 5
FK506-binding protein 12 5
p50 4
membrane-bound 4
SCR 4
X-linked 4
CACNL1A3 4
ADP 4
acetylcholine receptor 4
JP1 4
FK-506 binding protein 4
ADRB1 4
CREB 4
insulin-like growth factor 4
calreticulin 4
EF-hand domain 4
renin 4
p53 4
CASQ1 4
XRCC3 4
calsequestrin 1 4
EF-2 4
CA1 4
all-trans 4
cathepsin L 4
nitric oxide synthase 4
IP3R3 4
Met 4
membrane protein 4
IL-10 3
C-reactive protein 3
transforming growth factor-beta 3
InsP3R1 3
PCP 3
cardiac calsequestrin 3
uncoupling protein 3
sarcomeric 3
JP2 3
cytokine 3
DMPK 3
adaptor protein 3
SLN 3
ANOVA 3
parvalbumin 3
Chk1 3
cAMP-dependent protein kinase 3
BIN1 3
GSTM 3
Junctophilin-2 3
Rad51 3
immunophilin 3
DP1 3
XRCC1 3
RNS 3
SPR 3
alternatively spliced 3
IkappaBbeta 3
endonuclease 3
CIE 3
TDT 3
CPM 3
interacting protein 3
TTN 3
endothelin-1 3
hemoglobin 3
PKC 3
AMP-activated protein kinase 3
troponin I 3
sarcalumenin 3
IGF-1 3
Cathepsin L 3
MMR 2
PARP1 2
calpastatin 2
ACS 2
PC3 2
DR3 2
prolactin 2
hole 2
ITPR1 2
titin 2
FKBP1A 2
more...
Disease
malignant hyperthermia 172
myopathy 77
heart failure 31
cancer 26
Central core disease 26
hypertension 14
diabetes 12
tumor 11
depression 10
cold 9
centronuclear myopathy 9
DM1 8
multicore 7
GSH 6
SDS 6
stroke 6
scoliosis 6
aggression 6
periodic paralysis 5
CCD 5
CCD 5
prolapse 5
myocardial infarction 5
coronary artery disease 5
ischemia 5
tetanus 4
Duchenne muscular dystrophy 4
cardiovascular disease 4
Alzheimer's disease 4
respiratory failure 4
porcine stress syndrome 4
muscular dystrophy 4
obesity 4
prostate cancer 4
cardiomyopathy 4
SEM 4
tumor progression 3
mole 3
PCP 3
muscular atrophy 3
heart disease 3
nystagmus 3
myasthenia gravis 3
neuromuscular disorder 3
thymoma 3
dysplasia 3
ARVD 3
akinesia 3
mole 3
schizophrenia 3
CIE 3
Epstein 3
genetic disorder 2
ATM 2
atherosclerosis 2
preeclampsia 2
status epilepticus 2
bone metastases 2
lung carcinoma 2
lung cancer 2
lymphopenia 2
Dissociation 2
mental retardation 2
pulmonary hypertension 2
anemia 2
Catecholaminergic polymorphic ventricular tachycardia 2
mental retardation 2
sepsis 2
brucellosis 2
ovarian cancer 2
herpes simplex 2
confusion 2
Best 2
colon cancer 2
achromatopsia 2
Moore 2
epithelial ovarian cancer 2
breast cancer 2
leukemia 2
uterus 2
fits 2
Rett syndrome 2
sepsis 2
aggressiveness 2
hypertrophic cardiomyopathy 2
Lambert-Eaton myasthenic syndrome 2
congenital disorder 2
coronary heart disease 2
Still 2
migraine 2
glaucoma 2
congestive heart failure 2
ARVD2 2
terminal disease 2
insulinoma 2
XPG 2
strabismus 2
obstructive sleep apnea 2
iron deficiency 1
vascular disease 1
amnesia 1
conduct disorder 1
Liver mass 1
Thymus 1
abdominal aortic aneurysm 1
SAR 1
Huntington's disease 1
Brugada syndrome 1
central serous retinopathy 1
myocardial ischemia 1
Fanconi 1
wasting 1
amyotrophic lateral sclerosis 1
oppositional defiant disorder 1
cerebral infarction 1
Blocking 1
FCU 1
graft-versus-host disease 1
leukoencephalopathy 1
DBA 1
essential hypertension 1
metabolic syndrome 1
carcinogenesis 1
adenocarcinoma 1
paramyotonia 1
NAME 1
neuroblastoma 1
salmonellosis 1
scotoma 1
lymphadenopathy 1
hemiplegic migraine 1
pathological fracture 1
BLM 1
Adenovirus 1
CAM 1
retinitis pigmentosa 1
AAA 1
hydrocephalus 1
Thymus 1
Parkinson's disease 1
lactic acidosis 1
dermatomyositis 1
bronchopulmonary dysplasia 1
congenital neuromuscular disorder 1
head and neck cancer 1
optic neuritis 1
MTS 1
facial palsy 1
psychological distress 1
unipolar depression 1
addiction 1
gastric cancer 1
bone disease 1
pituitary adenoma 1
mammary tumor 1
gastroenteritis 1
polymyositis 1
immunodeficiency 1
craniosynostosis 1
cytomegalovirus 1
more...
Symptom
weakness 57
anesthesia 22
fatigue 19
ophthalmoplegia 14
hypotonia 13
pain 7
muscle rigidity 4
cachexia 3
exhaustion 3
myalgia 3
seizures 2
respiratory distress 2
photophobia 2
dyspnea 2
hypothermia 2
muscle stiffness 2
collapse 2
low back pain 2
analgesia 1
starvation 1
overweight 1
ataxia 1
chest pain 1
chills 1
asynergy 1
diarrhea 1
blurred vision 1
neck pain 1
nausea 1
thinning 1
HSA 1
paresis 1
headache 1
impaired motor coordination 1
Drug
caffeine 164
Cardiovasc 9
Vitamin A 7
Asn 5
ROS 5
DM1 5
K201 3
PCP 3
lysine 3
CPM 3
ABC 2
RFP 2
Triclosan 2
CaCl2 2
Alanine 2
PCB 2
all-trans-retinol 2
CaCl2 2
CaCl2 2
Spectrum 2
CoCl2 1
CTX 1
Dantrolene sodium 1
vitamin E 1
Saha 1
IL-2 1
Retinoic acid 1
CoCl2 1
RbCl 1
RbCl 1
Angiotensin II 1
Nephron 1
CTC 1
Fragment 1
nitroglycerin 1
Gel 1
CAM 1
VCR 1
Arsenic trioxide 1
NAG 1
Forskolin 1
EE2 1
CTC 1
Glutathione 1
ascorbate 1
Dermatol 1
EDR 1
Leaf 1
BLM 1
Enzyme
dihydropteridine reductase 35
ATPase 33
protein kinase 21
calcineurin 15
glutathione S-transferase 14
protein kinase C 6
PARP 6
trypsin 5
creatine kinase 5
AMPK 4
renin 4
cathepsin L 4
AMP-activated protein kinase 3
endonuclease 3
NADPH oxidase 3
RNase 3
calcium pump 3
PCP 3
caspase-3 3
CPM 3
RNase 3
reverse transcriptase 3
phospholipase C 3
NADPH oxidase 3
mitogen-activated protein kinase 3
protein phosphatase 2A 2
phosphodiesterase 2
ERK 2
catalase 2
NO synthase 2
ACS 2
NOS 2
acid phosphatase 2
acetylcholinesterase 2
CPT 2
lactate dehydrogenase 2
citrate synthase 1
m-calpain 1
acyl-CoA dehydrogenase 1
chloramphenicol acetyltransferase 1
S1 nuclease 1
calpain 3 1
ATP synthase 1
aequorin 1
TSR 1
complex I 1
adenosine deaminase 1
glyceraldehyde-3-phosphate dehydrogenase 1
phosphatidylinositol 3-kinase 1
MIP 1
ribonuclease 1
caspase-9 1
adenosine deaminase 1
enolase 1
proteasome 1
glyceraldehyde-3-phosphate dehydrogenase 1
succinate dehydrogenase 1
topoisomerase 1
carboxypeptidase A 1
CCS 1
AMPK 1
lipoprotein lipase 1
CAD 1
peroxidase 1
cathepsin D 1
aldolase 1
superoxide dismutase 1
CAD 1
topoisomerase 1
CAD 1
tyrosine hydroxylase 1
pyruvate kinase 1
hexokinase 1
CaMKII 1
PDK1 1
ribonuclease 1
inositol phosphatase 1
choline acetyltransferase 1
mu-calpain 1
adenosine kinase 1
Compound
calcium 496
caffeine 164
Ryanodine 102
Dec 83
DNA 71
ATP 55
oxygen 52
FK506 42
m-cresol 29
Mg2+ 27
cysteine 24
alanine 21
arginine 19
sodium 18
Clin 18
Dantrolene 18
water 15
threonine 14
nitric oxide 13
leucine 12
lysine 12
glutamate 11
potassium 10
nitrogen 10
phosphate 10
His 9
CO2 9
retinol 9
glucose 9
salt 9
Cardiol 9
AMP 9
Gly 8
GSH 7
ADP-ribose 7
Vitamin A 7
Ile 7
tyrosine 7
GSH 7
Asp 7
CHAPS 6
serine 6
SDS 6
NH2 6
retinoic acid 6
sulfate 6
pyrene 5
MHS 5
TOF 5
methionine 5
cAMP 4
Nicotinic acid adenine dinucleotide phosphate 4
ADP 4
ADP 4
ADP 4
tryptophan 4
Ruthenium 4
Ins(1,4,5)P3 4
hydrogen 4
Phe 4
Ruthenium 4
tryptophan 4
ethanol 3
PCP 3
fluorine 3
N-acetylcysteine 3
1-propanesulfonic acid 3
aldehyde 3
manganese 3
Austin 3
tryptophan 3
selenium 3
hydroxide 3
tryptophan 3
TDT 3
NAD 3
MAK 3
aldehyde 3
nickel 3
asparagine 3
ACh 2
glutamine 2
isoleucine 2
aspartic acid 2
cGMP 2
Alanine 2
isoleucine 2
Fluo-3 2
MDA 2
H2O2 2
cadmium 2
Cyclic ADP-ribose 2
ATF 2
benzene 2
aluminum 2
Triclosan 2
Nifedipine 2
Inositol 2
iron 2
Rapamycin 2
piperidine 2
chloroform 2
aspartic acid 2
CaCl2 2
phenol 2
aldosterone 2
ACTH 2
DIDS 2
noradrenaline 2
CMK 2
piperidine 2
UTP 2
Ruthenium red 2
Cholesterol 2
aspartic acid 2
ACS 2
acetate 2
aspartic acid 2
NADPH 2
hexane 2
ACS 2
NADPH 2
Vasopressin 2
Losartan 2
acrylamide 2
proline 2
pyrimidine 1
Norepinephrine 1
phenylphosphinic acid 1
DBA 1
glutamic acid 1
APT 1
PLA 1
silicon 1
5-HT 1
PPD 1
TCP 1
DBI 1
TNF 1
THP 1
Capsaicin 1
silver 1
CCP 1
Zwittergent 3-14 1
CPA 1
Halothane 1
AICAR 1
DBI 1
naphthoquinone 1
CPA 1
2-hydroxyethyl 1
Arsenic 1
XPA 1
CAT 1
TGR 1
cobalt 1
DCL 1
MCA 1
CCl4 1
phosphorus 1
more...