Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P21817 (
RyR1
)
1,154
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Aim:
To investigate the prognostic significance of pretreatment hemoglobin (HB)-to-red cell distribution width (RDW) ratio (
HRR
) in patients with muscle-invasive
bladder cancer
(MIBC).
Materials & methods:
The neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), prognostic nutritional index,
HRR
, HB and RDW were analyzed to assess their prognostic value using the Kaplan-Meier curves and Cox-regression analysis in 152 patients with MIBC.
Results:
Univariate analysis showed that the progression-free survival (PFS) was associated with NLR, SII,
HRR
, RDW, whereas overall survival (OS) was associated with NLR, SII, prognostic nutritional index,
HRR
, HB, RDW. In multivariate analysis,
HRR
was found to be an independent prognostic factor for both PFS and OS.
Conclusion:
HRR
is a new prognostic factor that can be used to predict PFS/OS in MIBC.
...
PMID:The prognostic significance of hemoglobin-to-red cell distribution width ratio in muscle-invasive bladder cancer. 3264 74