Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P21554 (cannabinoid receptor)
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Human Gene/Protein
cannabinoid receptor 13.1
CRIP1a 12.2
DDHD domain containing 1 12.1
G-protein coupled receptor 35 12.1
GPR55 protein 12.1
hexokinase 4 12.1
KIAA2013 12.1
GPR155 12.1
GPR55 11.5
Rap1GAPII 11.3
CB2 11.3
SH3-containing GRB2-like protein 3-interacting protein 1 11.1
GGT7 11.1
ZNF488 11.1
cannabinoid receptor 1 11.0
CNR1 11.0
NAPE-PLD 11.0
WIN 10.9
CB1 10.9
Cannabinoid receptor 1 10.8
fatty acid amide hydrolase 10.5
phosphatidic acid-preferring phospholipase A1 10.5
GPR63 10.5
GPR18 10.5
FAAH 10.4
5-hydroxytryptamine (serotonin) receptor 2C 10.3
CNR2 10.2
DHRS7 10.1
60S acidic ribosomal protein P0 10.1
Bombesin receptor subtype 3 10.1
chromobox homolog 7 10.1
GPR12 10.1
beta3 adrenoceptor 10.1
NAPEPLD 10.1
monoacylglycerol lipase 10.0
transglutaminase 5 9.9
GPR137 9.9
GPR6 9.8
D(4) dopamine receptor 9.8
DDHD1 9.8
ATPase homolog 9.8
MAEA 9.7
GPR135 9.7
TMED2 9.5
NECAB2 9.5
DAGLA 9.5
N-acyl phosphatidylethanolamine phospholipase D 9.5
ABHD12 9.4
SR14 9.3
transient receptor potential cation channel, subfamily V, member 1 9.2
Win 9.2
CRIP 9.1
TMED10 9.1
SGIP1 9.0
vanilloid receptor subtype 1 9.0
NECAB1 8.9
MGLL 8.9
TUBA1C 8.9
CYP4X1 8.9
CRIP1 8.8
THC 8.8
orphan G-protein coupled receptor 8.7
GPR3 8.7
G protein-linked receptor 8.6
acylglycerol kinase 8.6
DOR1 8.5
EBAF 8.5
putative G-protein-coupled receptor 8.5
ABHD6 8.5
CT9 8.4
URB 8.4
GPR35 8.4
ZBTB10 8.3
GDE1 8.3
GPR92 8.3
CBR 8.2
M6b 8.2
transcription factor A, mitochondrial 8.2
AGK 8.2
RORB 8.1
more...
Disease
acute alcohol effect 11.5
marijuana addiction 10.3
rapid reinstatement 9.8
THC 9.5
Cannabis 9.0
marijuana abuse 9.0
Mobitz type II atrioventricular block 8.6
Secretory diarrhea 8.4
age related bone loss 8.3
catalepsy 7.9
polydrug abuse 7.2
FCU 6.9
tocopherol deficiency 6.9
adult HD 6.9
perception disorder 6.8
AIDS wasting syndrome 6.8
functional diarrhea 6.7
Nicotine withdrawal 6.7
FGG 6.7
LPI 6.6
Nephrogenic adenoma 6.6
LTD 6.3
BDB 6.3
schizophrenic psychosis 6.3
Vascular dementia 6.1
drug addiction 6.0
polysubstance abuse 5.9
Retinal ischemia 5.9
pica 5.9
emotional trauma 5.8
anxiety state 5.7
pertussis 5.6
Immune thrombocytopenic purpura 5.6
Globus 5.5
DRM 5.5
OBX 5.4
Bezold 5.4
Opiates 5.3
ODA 5.3
cocaine addiction 5.3
Alcoholic liver disease 5.3
chronic cystitis 5.2
IDD 5.1
tobacco dependence 5.1
physical dependence 5.0
fear and anxiety 5.0
Frey 4.9
neonatal abstinence syndrome 4.9
Silence 4.9
Huntington's disease 4.9
abdominal obesity 4.8
blood cancer 4.8
hyperphagia 4.8
abnormal involuntary movements 4.8
nasopharyngitis 4.8
Immune thrombocytopenia 4.8
CAA 4.8
NS4 4.7
HIV encephalitis 4.7
bone cancer 4.7
disinhibition 4.6
NPS 4.6
emotionality 4.6
EMD 4.6
CNS diseases 4.6
Granuloma 4.6
cocaine abuse 4.6
memory impairment 4.5
chronic pain 4.5
mononeuropathy 4.5
PNET 4.5
acute alcohol intoxication 4.5
Overactive bladder 4.5
drug abuse 4.5
Brucella suis 4.5
PND 4.4
generalized seizure 4.4
CAA 4.4
anhedonia 4.3
CHR 4.3
more...
Symptom
Appetite suppression 9.8
unwanted hair 7.0
bewilderment 6.3
disturbed balance 6.3
startle reaction 5.9
Lower urinary tract symptoms 5.6
impaired motor coordination 5.5
bladder pain 5.5
Neuropathic pain 5.2
hypothermia 5.2
incoordination 5.1
acute pain 5.1
analgesia 5.0
hyperemesis 4.9
tonic-clonic seizure 4.8
cancer pain 4.7
spasticity 4.5
acute stress 4.5
Involuntary Movement 4.4
fasciculation 4.4
motor symptom 4.2
orofacial pain 4.2
memory loss 4.1
chorea 4.1
hyperesthesia 4.1
excessive sweating 3.9
partial seizure 3.7
hunger 3.6
pain 3.5
despair 3.5
cachexia 3.5
nausea and vomiting 3.3
dry skin 3.1
blepharospasm 3.1
nausea 3.1
abnormal gait 3.0
decreased appetite 2.9
dental pain 2.9
insomnia 2.7
vomiting 2.7
apathy 2.7
seizures 2.4
agitation 2.4
anorexia 2.4
overweight 2.3
arthralgia 2.3
tremor 2.1
skin irritation 2.1
bradykinesia 1.9
dysuria 1.9
spasm 1.8
masculinization 1.8
bone pain 1.5
ataxia 1.5
myalgia 1.4
tinnitus 1.4
functional recovery 1.4
hypercapnia 1.2
pelvic pain 1.1
dystonia 1.1
diarrhea 0.9
dizziness 0.9
constipation 0.8
lethargy 0.6
chest pain 0.6
hepatomegaly 0.6
hypotonia 0.6
sleepiness 0.5
vertigo 0.3
syncope -0.1
abdominal pain -0.8
anesthesia -1.0
angina -1.2
discomfort -1.3
cough -1.4
discomfort -1.5
starvation -1.5
dyspnea -1.7
headache -1.7
weakness -2.1
more...
Drug
Rimonabant 10.7
Olvanil 9.9
Nabilone 9.7
9-THC 9.4
Indiplon 8.9
Iodophenyl 8.6
Norleucine 8.3
Pramlintide 7.0
Dihydro 6.9
CG1 6.5
Coconut oil 6.4
Dipyrone 6.2
EMB 6.1
Corn oil 5.9
Soybean oil 5.8
SNL 5.6
Compound 9 5.1
RAL 5.1
Zmax 5.1
KCL 5.0
Pregnenolone 4.9
Gabapentin 4.9
CPO 4.9
Colombo 4.8
Fulvestrant 4.7
Orlistat 4.5
Maltose 4.3
Orphan 4.1
Clofibrate 4.0
TES 4.0
Apomorphine 3.8
Glide 3.8
Pilocarpine 3.8
Tocopherol 3.7
Ganciclovir 3.6
Rosiglitazone 3.5
Forskolin 3.4
Methylprednisolone 3.3
DFP 3.3
TTC 3.3
Reserpine 3.2
TAK 3.2
ICI 3.0
IL-11 3.0
DMAP 3.0
Azithromycin 2.9
Fentanyl 2.8
CCL 2.8
Pronase 2.8
Bayer 2.5
Diurnal 2.4
Award 2.3
PCP 2.3
Parkin 2.3
Parkin 2.3
Ethanol 2.2
Itraconazole 2.2
nitroglycerin 2.0
Estrogens 2.0
Capsicum 2.0
TMS 1.9
CDP 1.9
caffeine 1.9
Clonidine 1.9
Ouabain 1.8
CTX 1.8
MAP 1.8
G-CSF 1.8
Fluorescein 1.7
ETA 1.7
Alanine 1.7
Ringer's solution 1.7
ABC 1.6
Growth hormone 1.6
Growth hormone 1.5
CaCl2 1.5
CaCl2 1.5
CaCl2 1.4
CSF 1.4
HCH 1.4
more...
Enzyme
monoacylglycerol lipase 10.1
acylglycerol kinase 8.4
phospholipase D 6.3
pantetheinase 6.3
deaminase 6.3
lipoprotein lipase 5.9
caspase-10 5.6
caspase-10 5.6
triose-phosphate isomerase 5.6
phosphatidate phosphatase 5.4
inositol 3-kinase 5.3
neutral sphingomyelinase 4.7
adenylate cyclase 4.6
insulin-degrading enzyme 4.6
phospholipase A1 4.5
12-lipoxygenase 4.4
GRK2 4.4
CYP7A1 4.2
alpha-L-fucosidase 4.2
alpha-L-fucosidase 4.1
HK2 4.0
thromboxane synthase 4.0
phospholipase C 3.9
PAM 3.8
arylalkylamine N-acetyltransferase 3.7
chymase 3.7
acrosin 3.7
mitogen-activated protein kinase 3.7
tyrosine hydroxylase 3.7
hormone-sensitive lipase 3.6
phosphoinositide 3-kinase 3.6
DAT 3.6
alpha-L-fucosidase 3.6
alcohol oxidase 3.6
CPT 3.5
lipase 3.5
peptidyl-prolyl cis-trans isomerase 3.5
NO synthase 3.5
microsomal epoxide hydrolase 3.5
GABA transaminase 3.5
AMP-activated protein kinase 3.4
diacylglycerol acyltransferase 3.3
MPP 3.2
interstitial collagenase 3.2
glucokinase 3.2
diacylglycerol kinase 3.2
phosphatidylinositol 3-kinase 3.1
AMPK 3.1
farnesyltransferase 3.1
NOS 3.1
AMPK 3.1
CPT 3.1
guanylate cyclase 3.1
lipoxygenase 3.0
GRK5 3.0
CPT 2.9
protein kinase 2.9
Thy1 2.9
PKG 2.8
CPS 2.8
complex I 2.8
MEK 2.8
GSK 2.7
caspase-3 2.7
tryptase 2.7
phosphodiesterase 2.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.6
caspase-9 2.6
farnesyltransferase 2.6
protein phosphatase 2A 2.6
pyruvate carboxylase 2.6
apyrase 2.5
phosphoenolpyruvate carboxykinase 2.5
MIP 2.4
protein kinase C 2.4
dipeptidyl peptidase IV 2.4
prostate-specific membrane antigen 2.3
AOR 2.3
phospholipase A2 2.3
cholinesterase 2.3
more...
Compound
SR 141716 11.9
Oleoyl lysophosphatidic acid 11.5
2-(4-morpholinyl)ethyl 11.4
2-(4-morpholinyl)ethyl 11.3
2-octyn-1-ol 11.1
2,4-dichlorophenyl 10.9
2,4-dichlorophenyl 10.9
AEA 10.9
2-Arachidonylglycerol 10.5
AEA 10.5
3-ethyl-1H-indole 10.3
C6H10O4 10.3
nonanamide 10.3
Oleamide 10.0
1H-pyrazole 10.0
3-methylcyclohexanol 9.9
3-methylcyclohexanol 9.9
Isopimaric acid 9.9
1H-pyrazole 9.7
Palmitoylethanolamide 9.6
Tetrahydrocannabinol 9.5
4-methylglutamic acid 9.1
4-methylglutamic acid 9.1
Forsythiaside 9.1
9-octadecenyl 8.9
9-octadecenyl 8.9
Cannabidiol 8.8
NS 1619 8.8
Cannabinol 8.7
4-chlorophenyl 8.7
4-chlorophenyl 8.7
cyclohexanol 8.6
cyclohexanol 8.6
1-benzylpiperazine 8.5
Tingenone 8.4
2-phenyl-1H-indole 8.4
Oleoylethanolamide 8.4
1-piperidinecarboxamide 8.3
1-benzylpiperazine 8.3
Benzylpiperazine 8.0
Bisdemethoxycurcumin 7.9
trimethyl borate 7.9
Caryophyllene 7.9
Thujone 7.6
delta8-THC 7.6
Nafoxidine 7.6
1H-indazole 7.5
Kallidin 7.4
1H-indole-3-carboxylic acid 7.3
8-quinolinyl 7.2
2,6-dimethoxyphenyl 6.9
Levcromakalim 6.9
Glycerate 6.8
DAMGO 6.8
Naloxonazine 6.8
Etorphine 6.6
VPM 6.6
LY 294002 6.5
heptyl 6.4
heptyl 6.4
hexacosanoic acid 6.4
FUR 6.4
Oil Red 6.4
LTD 6.3
1H-pyrrole-2,5-dione 6.3
ECS 6.3
dUDP 6.2
DAG 6.2
S-allylcysteine 6.1
NOP 6.1
diethyl malonate 6.1
diethyl malonate 6.0
DAU 6.0
DAU 5.9
benzenesulfonyl fluoride 5.9
BayK8644 5.9
NPR 5.9
azepane 5.8
DPN 5.8
Pinene 5.7
more...