Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P21554 (
cannabinoid receptor
)
3,582
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cannabinoid receptor
3582
CB1
1036
CB2
714
WIN
359
Mol
227
Sep
221
fatty acid amide hydrolase
200
THC
188
GABA
127
cannabinoid receptor 1
112
GPR55
94
opioid receptor
91
monoacylglycerol lipase
87
insulin
74
CA1
69
cytokine
69
adenylyl cyclase
67
TRPV1
62
G protein-coupled receptor
58
adenylate cyclase
52
nitric oxide synthase
42
FAAH
42
lipopolysaccharide
42
CNR1
41
ERK1
40
AMP
38
G-protein-coupled receptor
38
cholecystokinin
37
axonal
36
MAPK
36
GTP
36
cyclooxygenase
35
phospholipase D
34
ATP
32
CA3
32
metabotropic glutamate receptor
32
caspase-3
31
transient receptor potential vanilloid 1
30
gut
30
NMR
30
IL-6
29
peroxisome proliferator-activated receptor
27
olfactory
26
NMDA receptor
26
leptin
25
p38
24
cyclooxygenase-2
24
G-protein coupled receptor
24
lipase
24
extracellular signal-regulated kinase
23
arrestin
23
ERK
23
endoplasmic reticulum
22
COX-2
21
tyrosine hydroxylase
21
ACS
21
Win
21
brain-derived neurotrophic factor
20
parvalbumin
19
LPS
19
NAPE-PLD
19
GPCR
19
orexin
18
substance P
17
calcitonin
17
GABA(A) receptor
17
glutamate receptor
17
TNF
17
mTOR
16
somatostatin
16
JNK
16
beta-endorphin
16
lymphoid
15
prolactin
15
GDP
15
AKT
15
Mem
15
neuropeptide Y
15
IL-10
15
p42
15
rat)
14
glial fibrillary acidic protein
14
ghrelin
14
GPR18
14
calcium channel
14
inducible nitric oxide synthase
14
oxytocin
14
CBR
13
collagen
13
hemoglobin
13
Bcl-2
13
CREB
13
adiponectin
13
vasopressin
13
phosphodiesterase
13
superoxide dismutase
13
proteinase 3
12
dopamine D1 receptor
12
estrogen receptor
12
spermatozoa
12
SAR
12
glucagon
12
muscarinic receptor
12
p44
12
adenosine receptor
11
SCH
11
dopamine D2 receptor
11
TNF-alpha
11
5-hydroxytryptamine
11
phosphatidylinositol 3-kinase
11
microsomal
11
tumor necrosis factor
11
PKA
11
tumor necrosis factor alpha
11
CD1
11
chemokine
11
proopiomelanocortin
10
MEK
10
myeloperoxidase
10
mu opioid receptor
10
orphan receptor
10
interacting protein
10
polypeptide
10
glucocorticoid receptor
10
HEK
10
Cannabinoid receptor 1
10
PI3K
9
bradykinin
9
GTP-binding protein
9
cytochrome P450
9
membrane-bound
9
acetylcholinesterase
9
rhodopsin
9
DBA
9
fused
9
synaptophysin
9
mitogen-activated protein
9
CBD
9
huntingtin
9
GSH
9
histone
9
glutamate transporter
9
dynorphin
9
CNR2
9
AMP-activated protein kinase
9
DAG
9
lipoxygenase
8
neuronal nitric oxide synthase
8
protein kinase B
8
growth hormone
8
PPAR
8
PKC
8
phosphoinositide 3-kinase
8
CBT
8
cage
8
STAT3
8
corticotropin-releasing factor
8
RhoA
8
MAP kinase
8
mast cell
8
more...
Disease
THC
188
Cannabis
175
obesity
167
depression
153
cancer
118
pertussis
110
schizophrenia
76
multiple sclerosis
71
catalepsy
63
Alzheimer's disease
59
tumor
58
psychosis
53
chronic pain
51
drug addiction
46
Parkinson's disease
46
diabetes
45
Huntington's disease
45
addiction
44
neuroblastoma
42
epilepsy
41
metabolic syndrome
34
stroke
33
type 2 diabetes
31
glioma
30
ischemia
26
cerebral ischemia
25
osteoporosis
25
NAME
25
drug abuse
24
cognitive impairment
24
glaucoma
22
fatty liver
22
atherosclerosis
21
anxiety disorders
20
hypertension
20
encephalomyelitis
20
memory impairment
19
hyperphagia
19
breast cancer
19
alcoholism
19
dyslipidemia
17
cold
17
HIV
16
uterus
16
tumor growth
16
leukemia
15
disinhibition
13
cardiovascular disease
13
SAR
12
posttraumatic stress disorder
12
dementia
12
amyotrophic lateral sclerosis
11
LTD
11
SCH
11
substance abuse
10
carcinoma
10
glioblastoma
10
cirrhosis
10
prostate cancer
10
abdominal obesity
9
GSH
9
astrocytoma
9
major depressive disorder
9
Frey
9
autism
9
intraocular pressure
9
hepatocellular carcinoma
9
DBA
9
tumor progression
8
emotionality
8
Evans
8
MCF
8
myocardial infarction
8
plaque
8
sepsis
8
colitis
8
asthma
8
hyperglycemia
8
mental illness
8
sepsis
8
migraine
8
colorectal cancer
8
arthritis
8
glioblastoma multiforme
7
CNS diseases
7
inflammatory bowel disease
7
neuropathy
7
fits
7
liver fibrosis
7
osteoarthritis
7
liver disease
7
colon cancer
7
rheumatoid arthritis
7
dyskinesia
6
physical dependence
6
anhedonia
6
status epilepticus
6
wasting
6
Blocking
6
brain edema
6
marijuana abuse
6
osteosarcoma
6
pica
6
adenocarcinoma
6
cholera
5
malnutrition
5
heart failure
5
pruritus
5
peripheral neuropathy
5
encephalitis
5
abortion
5
alcohol abuse
5
temporal lobe epilepsy
5
AIDS
5
cocaine addiction
5
chronic disease
5
melanoma
5
metabolic disorder
5
endometriosis
5
suicide
5
delirium
4
Placenta
4
hallucinations
4
EMD
4
substance use disorders
4
virus infection
4
ADHD
4
dysphoria
4
sickle cell disease
4
amnesia
4
tumorigenesis
4
lymphoma
4
glucose intolerance
4
fragile X syndrome
4
carcinogenesis
4
coronary heart disease
4
varices
4
alcohol use disorder
4
aggression
4
mantle cell lymphoma
4
myeloid leukemia
4
cystitis
4
pancreatic cancer
4
immunodeficiency
4
type 1 diabetes
4
aggressiveness
4
ACD
4
myocardial ischemia
4
IVA
4
Tourette syndrome
4
parkinsonism
4
hypothyroidism
4
fear and anxiety
4
cocaine abuse
4
diabetic nephropathy
4
acute pancreatitis
4
lung cancer
4
alcoholic fatty liver
4
HPA
3
anorexia nervosa
3
more...
Symptom
pain
339
analgesia
104
hypothermia
72
seizures
48
vomiting
24
nausea
22
spasticity
17
overweight
15
acute pain
15
acute stress
12
diarrhea
12
nausea and vomiting
11
cancer pain
9
tremor
9
anorexia
8
hunger
8
insomnia
8
memory loss
7
agitation
7
cachexia
7
incoordination
7
anesthesia
6
Neuropathic pain
6
ataxia
5
arthralgia
4
functional recovery
4
chorea
4
tonic-clonic seizure
4
chest pain
3
spasm
3
apathy
3
fasciculation
3
dystonia
2
despair
2
sleepiness
2
myalgia
2
abdominal pain
2
tinnitus
2
hypercapnia
2
constipation
2
bladder pain
2
disturbed balance
2
orofacial pain
2
headache
2
dizziness
2
masculinization
1
dry skin
1
dyspnea
1
syncope
1
dysuria
1
pelvic pain
1
skin irritation
1
fatigue
1
discomfort
1
startle reaction
1
Involuntary Movement
1
hyperemesis
1
bradykinesia
1
motor symptom
1
decreased appetite
1
starvation
1
discomfort
1
hepatomegaly
1
hypotonia
1
hyperesthesia
1
Appetite suppression
1
bewilderment
1
dental pain
1
excessive sweating
1
Lower urinary tract symptoms
1
bone pain
1
impaired motor coordination
1
cough
1
weakness
1
lethargy
1
abnormal gait
1
blepharospasm
1
partial seizure
1
angina
1
unwanted hair
1
vertigo
1
Drug
9-THC
127
Rimonabant
62
CSF
9
caffeine
9
Dihydro
7
Cardiovasc
7
MAP
6
lysine
5
Nabilone
5
ICI
5
Ethanol
5
Dermatol
5
nitroglycerin
4
ROS
4
CTX
4
IFN-gamma
3
ABC
3
vitamin E
3
Forskolin
3
Gabapentin
3
TTC
2
PCP
2
EE2
2
CaCl2
2
CaCl2
2
CaCl2
2
G-CSF
2
EMB
2
IL-2
2
Olvanil
2
Apomorphine
2
ascorbate
2
Biopolymers
2
CDP
1
Parkin
1
CTX
1
DFP
1
Alanine
1
Orphan
1
IL-11
1
Coconut oil
1
CCL
1
Ringer's solution
1
Clofibrate
1
Estrogens
1
Methylprednisolone
1
Award
1
CTX
1
Reserpine
1
Tocopherol
1
Growth hormone
1
Indiplon
1
Soybean oil
1
Asn
1
Fluorescein
1
Orlistat
1
Itraconazole
1
PTH
1
Iodophenyl
1
HCH
1
RAL
1
TES
1
Ganciclovir
1
Indomethacin
1
Clonidine
1
SNL
1
Zmax
1
Norleucine
1
DMAP
1
Capsicum
1
Ouabain
1
Pilocarpine
1
TMS
1
Pronase
1
Glide
1
Compound 9
1
CPO
1
Growth hormone
1
Rosiglitazone
1
CG1
1
Parkin
1
Fentanyl
1
Fluorescein
1
Glucagon
1
Fulvestrant
1
Dipyrone
1
ETA
1
KCL
1
Nephron
1
Azithromycin
1
Maltose
1
Bayer
1
TAK
1
Colombo
1
Pregnenolone
1
Diurnal
1
Pramlintide
1
Corn oil
1
ENT
1
Monit
1
Enzyme
mitogen-activated protein kinase
137
monoacylglycerol lipase
84
protein kinase
70
adenylate cyclase
53
lipoprotein lipase
48
deaminase
44
phospholipase D
34
ERK
31
protein kinase C
30
phospholipase C
30
caspase-3
26
lipase
24
ACS
21
tyrosine hydroxylase
21
NO synthase
20
AMP-activated protein kinase
15
MEK
14
phosphodiesterase
13
superoxide dismutase
13
acetylcholinesterase
13
AMPK
12
luciferase
11
phosphatidylinositol 3-kinase
11
peroxidase
11
focal adhesion kinase
10
phospholipase A2
8
phosphoinositide 3-kinase
8
calcineurin
8
guanylate cyclase
8
lipoxygenase
8
NOS
7
cholinesterase
7
complex I
7
lactate dehydrogenase
7
catalase
7
ATPase
7
aspartate aminotransferase
6
AMPK
6
reverse transcriptase
6
CPT
6
GSK
5
ACE
5
proteasome
5
caspase-9
5
renin
5
trypsin
4
RNA polymerase
4
MAP
4
hormone-sensitive lipase
3
phosphoenolpyruvate carboxykinase
3
transcriptase
3
glucokinase
3
succinate dehydrogenase
3
CPT
3
PAM
3
MIP
3
CPT
3
alkaline phosphatase
3
P-glycoprotein
3
alanine aminotransferase
3
monoamine oxidase
3
PARP
3
cdc2
2
adenosine deaminase
2
heme oxygenase
2
neutral sphingomyelinase
2
insulin-degrading enzyme
2
MPP
2
thymidine kinase
2
glutathione S-transferase
2
adenosine deaminase
2
chymotrypsin
2
chymase
2
ATP synthase
2
phosphoenolpyruvate carboxykinase
2
glyceraldehyde-3-phosphate dehydrogenase
2
citrate synthase
2
protein phosphatase 2A
2
caspase-8
2
PCP
2
thrombin
2
acylglycerol kinase
2
tryptase
2
DAT
2
glutathione peroxidase
2
NADPH oxidase
2
APC
2
caspase-1
2
CD10
2
PKG
2
NADPH oxidase
2
CYP7A1
2
pepsin
2
phosphoenolpyruvate carboxykinase
2
arginase
2
choline acetyltransferase
2
12-lipoxygenase
2
GRK2
2
soluble epoxide hydrolase
1
glutathione reductase
1
peptidyl-prolyl cis-trans isomerase
1
alpha-L-fucosidase
1
apyrase
1
triose-phosphate isomerase
1
microsomal epoxide hydrolase
1
ribonuclease
1
Thy1
1
PRE
1
phosphatidate phosphatase
1
RNase
1
AOR
1
PAL
1
alpha-L-fucosidase
1
glyceraldehyde-3-phosphate dehydrogenase
1
hexosaminidase
1
transglutaminase
1
alcohol oxidase
1
interstitial collagenase
1
inositol 3-kinase
1
acrosin
1
alpha-L-fucosidase
1
aldehyde dehydrogenase
1
alpha-glucosidase
1
glyceraldehyde-3-phosphate dehydrogenase
1
CaMKII
1
RNase
1
enolase
1
beta-galactosidase
1
thromboxane synthase
1
GABA transaminase
1
HK2
1
prostate-specific membrane antigen
1
cytochrome oxidase
1
isocitrate dehydrogenase
1
AST
1
xylanase
1
tissue plasminogen activator
1
pantetheinase
1
diaphorase
1
BAL
1
IKK
1
phospholipase A1
1
MDR
1
isocitrate dehydrogenase
1
caspase-10
1
xylanase
1
prostate-specific antigen
1
glutamine synthetase
1
NADH dehydrogenase
1
3-hydroxy-3-methylglutaryl coenzyme A reductase
1
MMP-3
1
glyceraldehyde-3-phosphate dehydrogenase
1
arylalkylamine N-acetyltransferase
1
diacylglycerol kinase
1
caspase-10
1
glutamate decarboxylase
1
collagenase
1
DNA methyltransferase
1
DNA ligase
1
dipeptidyl peptidase IV
1
more...
Compound
AEA
280
Dec
224
calcium
203
glutamate
150
AEA
131
4-chlorophenyl
129
2,4-dichlorophenyl
129
4-chlorophenyl
129
2,4-dichlorophenyl
129
cAMP
128
GABA
127
GABA
127
1H-pyrazole
115
1H-pyrazole
115
glycerol
111
glucose
85
ethanol
85
nitric oxide
82
water
82
Clin
62
DNA
61
oxygen
52
Tetrahydrocannabinol
46
potassium
46
5-HT
45
arginine
39
AMP
38
SR 141716
36
GTP
36
cyclohexanol
35
cyclohexanol
35
nicotinamide
33
NMDA
33
ATP
32
sodium
31
gamma-aminobutyric acid
29
noradrenaline
28
hydrogen
27
serine
25
Cannabidiol
24
phenol
22
ACS
21
ACS
21
AMPA
21
phosphate
18
piperidine
18
piperidine
18
tyrosine
18
DAMGO
17
TNF
17
acetate
17
salt
17
GDP
15
Cereb
15
alanine
15
Gly
14
cGMP
13
Phe
13
HCl
13
cysteine
13
nitrogen
12
sulfate
11
CO2
11
Neuronal
11
Oleamide
11
LTD
11
MEK
10
DAD
10
methionine
10
heptyl
10
Cardiol
10
heptyl
10
Palmitoylethanolamide
10
1H-indole
9
methanol
9
DBA
9
DAG
9
PGE
9
leucine
9
DBA
9
caffeine
9
GSH
9
Capsaicin
9
GSH
9
DBA
9
2-hydroxyethyl
8
2-hydroxyethyl
8
CNQX
8
2-hydroxyethyl
8
DMSO
8
2-hydroxyethyl
8
2-hydroxyethyl
8
2-hydroxyethyl
8
2-hydroxyethyl
8
MPTP
8
2-hydroxyethyl
8
Glutamate
8
Pac
8
Morphine
8
piperazine
8
pyridine
8
PMSF
7
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
7
palmitic acid
7
asparagine
7
PMA
7
ACTH
7
2-(4-morpholinyl)ethyl
7
COS
7
tryptophan
7
2-(4-morpholinyl)ethyl
7
4-nitrophenyl
7
Nicotine
7
galactose
7
lysine
7
ACh
7
Cocaine
6
ADP
6
TEA
6
TEA
6
morpholine
6
quinoline
6
acetic acid
6
cyclopentyl
6
PMA
6
fluorine
6
D-Ala
6
C-3
6
iodine
6
ADP
6
quinoline
6
Arachidonic acid
6
ADP
6
silver
6
PGE2
6
MTT
5
aspartic acid
5
resorcinol
5
His
5
AAT
5
ECS
5
naphthalene
5
Adenosine
5
Asp
5
Dopamine
5
1H-indazole
5
urea
5
ICI
5
acetonitrile
4
THP
4
CTX
4
tryptophan
4
Corticosterone
4
Caryophyllene
4
PEA
4
VPM
4
threonine
4
MAP
4
GMP
4
tryptophan
4
more...