Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20366 (substance P)
 21,176 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
substance P 10.6
gamma preprotachykinin 10.6
two pore domain K+ channel 10.6
Preprotachykinin B 10.6
solute carrier family 35, member D3 10.6
trp7 10.4
NK-2 receptor 10.3
Neurokinin-B 10.3
neurokinin-2 receptor 10.2
SR140 10.2
NK2 10.1
neurokinin 1 receptor 10.1
NKB 10.0
neurokinin B 10.0
NK3 receptor 9.9
preprotachykinin B 9.9
TACR2 9.8
Neurokinin B 9.7
hHK1 9.6
GRP/bombesin receptor 9.6
netrin G2 9.6
mitogen- and stress-activated protein kinase 2 9.6
P2X purinoceptor 2 9.6
NKA 9.3
SKR 9.3
NK1 9.3
NK-receptor 9.2
Neurokinin-2 receptor 9.0
adenylate cyclase-inhibiting 9.0
NK3R 8.9
TAC1 8.7
SP5 8.7
NKIR 8.6
PSDC 8.6
GLRA4 8.6
developmentally regulated GTP binding protein 2 8.6
Endopeptidase-2 8.6
PLEKHH2 8.6
NK-2 8.5
NKD 8.4
TAC3 8.3
dimethyladenosine transferase 8.2
Apoptosis repressor with CARD 8.2
MRGPRX1 8.2
DC21 8.2
Neuropeptide S receptor 1 8.2
SP-I 8.2
calcitonin 2 8.2
protocadherin 20 8.2
Neutral endopeptidase 8.2
vanilloid receptor subtype 1 8.2
CGRP 8.2
neurotensin 8.2
vasoactive intestinal peptide 8.2
EKC 8.1
CD57 8.1
NK receptor 8.0
calcitonin 8.0
vasoactive intestinal peptide (VIP) 8.0
MRGPRX2 8.0
galanin 8.0
preprodynorphin 8.0
potassium inwardly-rectifying channel 8.0
P2Y2-like 8.0
TRP7 8.0
Parotid secretory protein 8.0
Prolyl endopeptidase 7.9
SP4 7.9
short form 7.9
Leu-enkephalin 7.8
neuropeptide Y 7.8
bombesin 7.8
Adenosine A3 receptor 7.7
CAPZ 7.7
VILL 7.7
CAP-R 7.7
Metalloelastase 7.7
checkpoint with forkhead and ring finger domains 7.7
cytosolic aminopeptidase P 7.7
IGLJ3 7.7
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Disease
Idiopathic vulvodynia 10.6
Antral G-cell hyperplasia 10.6
gastrectasis 10.6
Diabetic diarrhea 9.0
pediatric anaplastic astrocytoma 8.2
Diabetic keratopathy 8.1
Tail-biting 8.0
Femoral artery occlusion 8.0
occupational and social impairment 8.0
reflex disorder 8.0
MMEP 7.7
Chronic polyarthritis 7.7
osteolytic sarcoma 7.6
Lissauer 7.5
sympatheticotonia 7.2
Neurotrophic keratopathy 7.2
Gastrointestinal inflammation 7.1
Other dermatoses 6.9
LAD2 6.8
chalasia 6.7
VVS 6.6
Somatostatinoma 6.6
GTP cyclohydrolase I deficiency 6.6
Diabetic cystopathy 6.6
Prurigo nodularis 6.5
Autotomy 6.4
Milwaukee shoulder 6.2
monoarthritis 6.2
sesamoiditis 6.1
Milwaukee shoulder 6.1
multiple endocrine neoplasia 6.0
Neuroaxonal dystrophy 6.0
proctalgia fugax 6.0
vascular headache 5.9
chromhidrosis 5.8
small bowel ileus 5.8
Renal pelvis 5.8
acute schizophrenic episode 5.8
Renal pelvis 5.8
APUDoma 5.7
uvea 5.6
cutaneous leiomyoma 5.5
SMON 5.5
nasal allergy 5.4
high renin hypertension 5.4
inflammatory joint disease 5.4
CAPA 5.3
GALE 5.3
Carotid body 5.3
Carotid body 5.3
Carotid body 5.3
varices 5.3
Somatostatinomas 5.3
Swine dysentery 5.3
Ciliary body 5.3
Ciliary body 5.3
demineralization of bone 5.2
achillodynia 5.2
pediatric liver cancer 5.2
vasomotor rhinitis 5.1
carcinoid syndrome 5.1
nerve lesion 5.1
Alternating hemiplegia of childhood 5.1
progressive chorea 5.1
Subependymal giant cell astrocytoma 5.1
angiectasis 5.1
prurigo 5.0
interstitial cystitis 5.0
Morphine dependence 5.0
tennis elbow 5.0
Convulsive status epilepticus 5.0
regional pain syndrome 5.0
duodenal polyp 5.0
Malassez 5.0
Sluder 4.9
Vernal keratoconjunctivitis 4.9
Opiates 4.9
Hypertrophic pulmonary osteoarthropathy 4.9
Lichen planopilaris 4.9
Granuloma 4.8
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Symptom
Gurgling 10.6
Cutaneous hyperalgesia 9.0
Skin hyperemia 9.0
Persistent dry cough 8.7
peritoneal pain 8.2
Sharp pain 8.2
Esophageal pain 7.4
Sympathetically maintained pain 7.2
Deafferentation 7.2
prickling sensation 6.6
Visceral pain 6.0
Other pain 5.9
retching 5.8
Peripheral neuropathic pain 5.6
UTI symptoms 5.6
sighing 5.5
Watery diarrhea 5.5
retrosternal discomfort 5.4
Inflammatory pain 5.3
sinus congestion 5.2
bladder pain 4.9
labored breathing 4.8
localized edema 4.8
nerve pain 4.8
Flare 4.7
Functional constipation 4.6
Ear swelling 4.6
Spontaneous nystagmus 4.6
sneezing 4.5
Grimace 4.5
Neuropathic pain 4.4
skin pain 4.3
Excitable 4.1
hypalgesia 4.1
Vulvodynia 4.1
Lower urinary tract symptoms 4.0
Anterior knee pain 4.0
Chronic pelvic pain 3.9
generalized pain 3.9
No pain 3.8
acute pain 3.8
nausea and vomiting 3.7
Macula 3.7
orofacial pain 3.7
analgesia 3.7
dental pain 3.6
Crushing 3.6
nasal congestion 3.6
vestibulitis 3.5
hyperesthesia 3.5
Postoperative nausea and vomiting 3.5
urinary frequency 3.4
rhinorrhea 3.4
chronic constipation 3.4
pain 3.4
leg cramps 3.4
Excitability 3.2
cough 3.2
constipation 3.1
neuralgia 3.1
pachyonychia 3.0
chronic cough 3.0
skin irritant 3.0
vomiting 3.0
rectal pain 3.0
Gastrointestinal symptoms 3.0
bradypnea 2.9
chorea 2.8
tonic seizure 2.8
abnormal breathing 2.8
flushing 2.8
disturbed balance 2.7
Welt 2.7
dysesthesia 2.7
anal pain 2.7
twitching 2.6
acute stress 2.6
postnasal drip 2.5
hypercapnia 2.5
abdominal cramps 2.5
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Drug
Zanthoxylum fruit 9.0
Aprepitant 8.8
Fosaprepitant dimeglumine 8.6
D-Aspartic Acid 8.6
Rimadyl 8.6
Ezlopitant 8.4
Phosphoramidon 8.2
Netupitant 8.2
Imidapril hydrochloride 8.2
Bepotastine besilate 8.1
Tubocurarine chloride 8.0
Setoperone 7.7
Cetraxate hydrochloride 7.6
Berberine sulfate 7.6
Phenylephrine hydrochloride 7.4
Olvanil 7.4
Epinastine 7.3
Leucin 7.2
Limaprost 7.2
Ecabet sodium 7.1
Sodium borate 7.1
Neotrofin 7.0
Etidronate disodium 7.0
Ciclazindol 7.0
Bisacodyl 6.9
Vapreotide 6.9
Zaltoprofen 6.8
Clenbuterol hydrochloride 6.7
CCl2F2 6.6
Zinc gluconate 6.6
Lioresal 6.6
Prednicarbate 6.2
Nedocromil sodium 6.0
Kytril 6.0
Guanethidine 5.9
Kytril 5.9
Atropine 5.9
Brofaromine 5.7
Renzapride 5.7
Levocabastine 5.6
Tryptophane 5.6
Spiriva 5.5
Palonosetron hydrochloride 5.5
Olopatadine hydrochloride 5.4
Rizatriptan 5.4
Vinpocetine 5.4
Enalaprilat 5.3
Enalaprilat 5.3
FML 5.3
Drotrecogin alfa 5.3
Drotrecogin alfa 5.3
Dazmegrel 5.2
Tubocurarine 5.2
Hoelen 5.2
Ketotifen 5.2
Peppermint oil 5.2
Gly-Tyr-Gly 5.2
Ozagrel 5.1
ISP 5.0
Platelet Activating Factor 5.0
Sivelestat 5.0
Histamine 5.0
1-Deoxynojirimycin 4.9
Citric acid 4.9
Ipratropium bromide 4.8
CTZ 4.8
Sodium nitroprusside 4.8
Morphine sulfate 4.7
Zaditen 4.7
Methergin 4.7
Ibudilast 4.7
Proglumide 4.6
Secretin 4.6
Pregabalin 4.6
OctreoScan 4.6
Flunixin 4.6
Dextropropoxyphene 4.6
Ketalar 4.5
TAK 4.5
Tegaserod 4.4
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Enzyme
clostridial aminopeptidase 9.6
gamma-renin 9.6
peptide hormone inactivating endopeptidase 9.0
oligoendopeptidase F 9.0
neurolysin 7.2
pepsin B 7.1
aminopeptidase P 6.4
prolyl endopeptidase 6.4
choline acetyltransferase 6.3
CD10 6.2
dopamine beta-hydroxylase 6.2
tyrosine hydroxylase 6.1
aminopeptidase Y 6.1
carboxypeptidase S 5.9
duodenase 5.9
thimet oligopeptidase 5.7
NADPH-diaphorase 5.5
DAP II 5.4
tryptase 5.2
dipeptidyl peptidase IV 5.1
chymase 5.1
CPN 5.1
endothelin-converting enzyme 4.9
carboxypeptidase E 4.9
PGE2-9-ketoreductase 4.9
glutamate decarboxylase 4.8
diaphorase 4.8
stem bromelain 4.8
phenylethanolamine N-methyltransferase 4.7
VIP1 4.7
tryptophan hydroxylase 4.6
nardilysin 4.6
oligopeptidase B 4.6
aromatic L-amino acid decarboxylase 4.5
Ins(1,4,5)P3 3-kinase 4.3
NO synthase 4.1
thromboxane synthase 4.0
carboxypeptidase B 3.9
enolase 3.9
adenylate cyclase 3.8
ceramide kinase 3.8
transcarboxylase 3.8
botulinum neurotoxin 3.7
diaphorase 3.7
acetylcholinesterase 3.7
phospholipase C 3.7
NQO1 3.7
ACE 3.6
proline iminopeptidase 3.6
CD13 3.5
hatching enzyme 3.5
tripeptidase 3.5
GABA transaminase 3.5
catechol oxidase 3.5
SMP 3.5
NOS 3.5
meprin 3.4
tripeptidyl peptidase 3.4
aminopeptidase A 3.4
PI-PLC 3.4
carboxypeptidase Y 3.4
histidine decarboxylase 3.4
STK 3.3
peroxidase 3.3
guanylate cyclase 3.3
cathepsin S 3.2
pyroglutamate aminopeptidase 3.2
ScpA 3.1
CAO 3.1
DOPA decarboxylase 3.1
KLK7 3.0
sphingosine kinase 3.0
protein kinase C 3.0
isopeptidase 3.0
thermolysin 3.0
kynurenine 3-monooxygenase 3.0
SST 3.0
tyrosine decarboxylase 3.0
cathepsin C 3.0
methionine synthase reductase 2.9
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Compound
Methyl thiosalicylate 10.6
Ozagrel hydrochloride 10.6
Substance P 10.6
Allotetrahydrocorticosterone 10.6
Rigin 10.6
4-morpholinecarboxamide 9.0
3,4-dichlorophenylalanine 9.0
SP-G 8.7
4'-Phosphopantetheine 8.6
3,4-dichlorophenylalanine 8.6
1-pyrrolidinecarboxamide 8.6
Phosphoramidon 8.2
diphenylacetonitrile 8.2
Saprol 8.2
SP 1 8.2
4-phenyl-3-butenoic acid 8.1
Capsaicin 8.1
[1,1'-biphenyl]-4-carbonitrile 8.0
12-hydroxy-9-octadecenoic acid 8.0
Alverine citrate 8.0
12-hydroxy-9-octadecenoic acid 8.0
Endomorphin-2 7.8
Z-Gly-Pro-Leu-Gly-Pro 7.7
Quinacridone 7.7
DCPM 7.6
Phenylephrine hydrochloride 7.6
Berberine sulfate 7.6
4-piperidinecarboxylic acid 7.6
Emedastine 7.6
Berberine sulfate 7.6
5-amino-2-hydroxybenzoic acid 7.6
Thiorphan 7.4
Columbianetin 7.4
U 50488 7.3
L-Homocysteic acid 7.3
Polygodial 7.3
cis-Urocanic acid 7.2
2-hydroxy-5-methoxybenzoic acid 7.2
Asperlicin 7.2
Kallidin 7.2
Neurotensin 7.1
Calcitonin 7.1
Bromoacetylcholine 7.1
DMHP 7.1
Olopatadine 7.0
DuP 697 7.0
10,11-dihydro-5H-dibenzo[a,d]cycloheptene 7.0
Resiniferatoxin 7.0
2-phenylquinoline 6.9
2-methylpropanamide 6.9
Teprotide 6.9
2,2-dichloroethanol 6.9
Arg-vasopressin 6.8
3-hydroxyaspartic acid 6.7
3-hydroxyaspartic acid 6.7
Hepoxilin A3 6.7
3-hydroxyaspartic acid 6.7
Sodium ricinoleate 6.7
Urushiol 6.7
1-piperidinecarboxamide 6.7
3-hydroxyaspartic acid 6.7
Methionine enkephalin 6.7
Lys-vasopressin 6.6
Dynorphin 6.6
H-69 6.6
FPL64176 6.6
trioxilin A3 6.6
3-hydroxyaspartic acid 6.6
Cetraxate 6.6
cyclohexylacetic acid 6.6
Norathyriol 6.5
N-Acetylmethionine 6.5
Hoe 6.5
Bradykinin 6.4
3-hydroxyaspartic acid 6.4
Gabaculine 6.3
Amarogentin 6.3
Neomycin sulfate 6.3
Hexamethonium 6.3
Z-Gly-Pro 6.3
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