Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20366 (substance P)
21,176 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
substance P 21176
calcitonin 2970
somatostatin 1745
Sep 1398
neuropeptide Y 1395
NK1 1374
polypeptide 1287
bradykinin 1056
vasoactive intestinal peptide 931
neurotensin 894
NK2 775
cholecystokinin 774
tyrosine hydroxylase 702
Met 671
short form 637
vasoactive intestinal peptide (VIP) 637
galanin 609
neurokinin B 608
nitric oxide synthase 547
beta-endorphin 544
Mol 541
bombesin 535
5-hydroxytryptamine 486
dynorphin 484
gut 474
CD57 434
GABA 412
neutral endopeptidase 391
mast cell 387
CGRP 368
neurokinin 1 receptor 355
axonal 347
gastrin 346
vasopressin 342
peroxidase 338
nerve growth factor 337
NK3 receptor 334
NKA 333
choline acetyltransferase 324
VIP 310
ATP 309
angiotensin II 298
cytokine 287
insulin 273
Leu-enkephalin 257
NK-2 244
glucagon 236
acetylcholinesterase 230
opioid receptor 217
Calcitonin 214
oxytocin 212
calbindin 199
Neuropeptide Y 195
peptidase 193
olfactory 181
CCK 180
Met-enkephalin 177
adenylate cyclase 174
IgE 172
NKB 171
gastrin-releasing peptide 160
motilin 159
secretin 157
NK-2 receptor 156
PGP 9.5 156
thyrotropin-releasing hormone 150
cyclooxygenase 150
corticotropin-releasing factor 149
pancreatic polypeptide 147
AMP 147
tumor necrosis factor 146
IL-6 141
neuronal nitric oxide synthase 131
Gen 130
ACTH 128
transient receptor potential vanilloid 1 126
NMDA receptor 125
Ang II 125
TNF 119
NPY 119
more...
Disease
asthma 354
depression 344
cancer 326
varices 284
tumor 235
diabetes 209
Evans 199
multiple endocrine neoplasia 198
hypertension 176
chronic pain 175
pruritus 170
NAME 159
migraine 151
arthritis 144
Parkinson's disease 139
pertussis 129
Alzheimer's disease 128
cold 127
ischemia 102
uterus 100
atopic dermatitis 97
rheumatoid arthritis 94
Huntington's disease 93
SEM 89
cholera 88
psoriasis 80
colitis 74
stroke 73
cornea 71
inflammatory bowel disease 70
irritable bowel syndrome 69
carcinoid 68
astrocytoma 68
osteoarthritis 67
schizophrenia 61
ureter 60
fibromyalgia 60
neuroblastoma 59
neuropathy 59
dermatitis 53
ulcerative colitis 53
celiac disease 52
atherosclerosis 51
SCH 49
Frey 49
carcinoma 48
bronchospasm 48
allergic rhinitis 47
chronic renal failure 45
diabetic neuropathy 43
acute pancreatitis 43
metastases 41
major depressive disorder 40
plaque 40
small cell lung cancer 40
SDS 40
urethra 39
heart failure 39
breast cancer 38
obesity 38
cystitis 38
leukemia 37
aggression 36
peripheral neuropathy 36
Crohn's disease 35
glioma 35
addiction 35
HIV 34
urticaria 33
sepsis 32
periosteum 32
anxiety disorders 31
sepsis 31
anaphylaxis 30
chronic obstructive pulmonary disease 30
dementia 30
carcinoid syndrome 30
conjunctiva 29
PAF 29
sudden infant death syndrome 29
more...
Symptom
pain 1787
analgesia 236
vomiting 167
cough 144
anesthesia 127
headache 121
diarrhea 86
nausea and vomiting 84
Welt 69
seizures 66
constipation 60
nausea 41
acute pain 36
erythema 33
hypercapnia 30
abdominal pain 30
sneezing 29
flushing 29
low back pain 27
back pain 23
spasm 23
retching 20
discomfort 20
Neuropathic pain 20
discomfort 20
functional recovery 20
fatigue 18
acute stress 18
dystonia 17
hypothermia 17
myalgia 17
arthralgia 16
dyspnea 16
angina 16
anorexia 16
rhinorrhea 16
Deafferentation 16
pelvic pain 14
spasticity 12
hyperoxia 11
chronic cough 11
starvation 11
hunger 11
acidity 10
ataxia 10
cancer pain 10
respiratory distress 10
chorea 10
neuralgia 10
dental pain 10
agitation 9
exhaustion 9
chronic constipation 9
nasal congestion 9
urinary frequency 8
orofacial pain 8
tachypnea 8
bladder pain 8
twitching 8
dry eye 8
weakness 7
facial pain 7
insomnia 7
bradykinesia 6
skin irritation 6
bone pain 6
shoulder pain 5
neck pain 5
knee pain 5
numbness 5
Ill 5
distraction 5
wheezing 5
Visceral pain 5
collapse 5
sleepiness 4
hyperesthesia 4
dysesthesia 4
polydipsia 4
apathy 4
more...
Drug
Dermatol 222
Atropine 131
Histamine 116
Cardiovasc 85
CSF 76
Indomethacin 68
lysine 65
nitroglycerin 64
Nephron 63
Asn 53
citric acid 49
IFN-gamma 49
Aprepitant 47
Phosphoramidon 44
IL-2 38
caffeine 38
ICI 33
Biopolymers 33
Gel 30
Captopril 28
Angiotensin II 28
MAP 23
Clonidine 22
Asthma 19
Sodium nitroprusside 18
Glucagon 17
DHT 17
DHT 17
p75 17
ascorbate 16
Monit 16
ETA 16
Forskolin 15
TAK 15
HCH 15
CTX 15
CaCl2 13
CaCl2 13
CaCl2 13
GRF 13
Secretin 12
Phentolamine 11
Ethanol 11
Leaf 11
Guanethidine 11
Citric acid 10
CTX 10
Theophylline 10
CTX 10
ISP 10
PCP 10
Raloxifene 9
Apomorphine 9
Kainic acid 8
ABC 8
Ringer's solution 8
Nedocromil sodium 8
Allergen 8
Nitric Oxide 8
ROS 7
Scopolamine 7
NH3 7
Pregabalin 7
Adenosine triphosphate 7
PTH 7
BoNT/A 7
Ketotifen 7
Salbutamol 6
Fluorescein 6
vitamin E 6
DFP 6
Reserpine 6
GHRP 6
Methylene blue 6
Diphenhydramine 6
Tubocurarine 6
NADH 6
Paraffin 6
Pilocarpine 5
Propofol 5
more...
Enzyme
tyrosine hydroxylase 677
CD10 480
peroxidase 428
choline acetyltransferase 326
protein kinase C 262
acetylcholinesterase 244
NO synthase 178
adenylate cyclase 178
phospholipase C 155
ACE 149
mitogen-activated protein kinase 146
protein kinase 137
ERK 127
NADPH-diaphorase 120
trypsin 119
renin 78
superoxide dismutase 67
dopamine beta-hydroxylase 67
tryptase 67
collagenase 58
ATPase 56
acid phosphatase 55
guanylate cyclase 55
NOS 53
diaphorase 52
phospholipase A2 52
diaphorase 52
NQO1 52
phosphodiesterase 51
prolyl endopeptidase 44
chymotrypsin 43
thrombin 42
catalase 41
glutamate decarboxylase 41
lipoxygenase 41
dipeptidyl peptidase IV 39
reverse transcriptase 38
cholinesterase 37
enolase 36
alkaline phosphatase 35
chymase 31
caspase-3 30
CD13 28
tryptophan hydroxylase 28
monoamine oxidase 27
MEK 26
kallikrein 26
luciferase 24
RNA polymerase 20
lactate dehydrogenase 19
urease 18
urease 18
focal adhesion kinase 18
ACS 17
cytochrome oxidase 17
calcineurin 17
lysozyme 17
botulinum neurotoxin 17
RNase 17
neuraminidase 15
carbonic anhydrase 15
MIP 15
transglutaminase 15
RNase 15
transcriptase 14
hyaluronidase 14
aspartate aminotransferase 14
hyaluronidase 13
beta-galactosidase 13
MMP-3 13
hexosaminidase 13
endothelin-converting enzyme 13
tissue plasminogen activator 13
NADPH oxidase 13
pepsin 12
adenosine deaminase 12
adenosine deaminase 12
aminopeptidase P 12
MAP 12
NADPH oxidase 12
more...
Compound
Substance P 3231
Dec 1538
calcium 1337
methionine 972
arginine 719
nitric oxide 666
glutamate 640
5-HT 622
sodium 621
leucine 606
noradrenaline 555
water 541
potassium 489
Phe 489
Capsaicin 470
Clin 468
GABA 425
GABA 417
nitrogen 319
ATP 317
Gly 308
tyrosine 304
NH2 281
lysine 271
phosphate 268
His 248
gamma-aminobutyric acid 246
Calcitonin 213
cAMP 207
ACh 205
alanine 200
DNA 184
oxygen 184
phosphorus 177
NMDA 169
Ile 168
acetate 162
AMP 156
Atropine 131
glucose 131
ACTH 129
cGMP 128
Bradykinin 127
Asp 126
ethanol 125
acetic acid 123
salt 119
TNF 119
Histamine 116
isoleucine 114
isoleucine 114
sulfate 113
silver 111
hydrogen 101
Neurotensin 91
proline 90
Morphine 90
zinc 90
PGE2 89
serine 87
CO2 86
GTP 83
Neuronal 80
threonine 80
prostacyclin 79
TRH 77
tryptophan 74
Naloxone 73
Tetrodotoxin 73
AMPA 66
Indomethacin 66
HCl 65
nitrate 65
benzamide 64
ammonium 62
Mg2+ 62
Norepinephrine 60
formaldehyde 59
Dopamine 59
PGE 58
more...