Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P20366 (
substance P
)
21,176
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
substance P
21176
calcitonin
2970
somatostatin
1745
Sep
1398
neuropeptide Y
1395
NK1
1374
polypeptide
1287
bradykinin
1056
vasoactive intestinal peptide
931
neurotensin
894
NK2
775
cholecystokinin
774
tyrosine hydroxylase
702
Met
671
short form
637
vasoactive intestinal peptide (VIP)
637
galanin
609
neurokinin B
608
nitric oxide synthase
547
beta-endorphin
544
Mol
541
bombesin
535
5-hydroxytryptamine
486
dynorphin
484
gut
474
CD57
434
GABA
412
neutral endopeptidase
391
mast cell
387
CGRP
368
neurokinin 1 receptor
355
axonal
347
gastrin
346
vasopressin
342
peroxidase
338
nerve growth factor
337
NK3 receptor
334
NKA
333
choline acetyltransferase
324
VIP
310
ATP
309
angiotensin II
298
cytokine
287
insulin
273
Leu-enkephalin
257
NK-2
244
glucagon
236
acetylcholinesterase
230
opioid receptor
217
Calcitonin
214
oxytocin
212
calbindin
199
Neuropeptide Y
195
peptidase
193
olfactory
181
CCK
180
Met-enkephalin
177
adenylate cyclase
174
IgE
172
NKB
171
gastrin-releasing peptide
160
motilin
159
secretin
157
NK-2 receptor
156
PGP 9.5
156
thyrotropin-releasing hormone
150
cyclooxygenase
150
corticotropin-releasing factor
149
pancreatic polypeptide
147
AMP
147
tumor necrosis factor
146
IL-6
141
neuronal nitric oxide synthase
131
Gen
130
ACTH
128
transient receptor potential vanilloid 1
126
NMDA receptor
125
Ang II
125
TNF
119
NPY
119
more...
Disease
asthma
354
depression
344
cancer
326
varices
284
tumor
235
diabetes
209
Evans
199
multiple endocrine neoplasia
198
hypertension
176
chronic pain
175
pruritus
170
NAME
159
migraine
151
arthritis
144
Parkinson's disease
139
pertussis
129
Alzheimer's disease
128
cold
127
ischemia
102
uterus
100
atopic dermatitis
97
rheumatoid arthritis
94
Huntington's disease
93
SEM
89
cholera
88
psoriasis
80
colitis
74
stroke
73
cornea
71
inflammatory bowel disease
70
irritable bowel syndrome
69
carcinoid
68
astrocytoma
68
osteoarthritis
67
schizophrenia
61
ureter
60
fibromyalgia
60
neuroblastoma
59
neuropathy
59
dermatitis
53
ulcerative colitis
53
celiac disease
52
atherosclerosis
51
SCH
49
Frey
49
carcinoma
48
bronchospasm
48
allergic rhinitis
47
chronic renal failure
45
diabetic neuropathy
43
acute pancreatitis
43
metastases
41
major depressive disorder
40
plaque
40
small cell lung cancer
40
SDS
40
urethra
39
heart failure
39
breast cancer
38
obesity
38
cystitis
38
leukemia
37
aggression
36
peripheral neuropathy
36
Crohn's disease
35
glioma
35
addiction
35
HIV
34
urticaria
33
sepsis
32
periosteum
32
anxiety disorders
31
sepsis
31
anaphylaxis
30
chronic obstructive pulmonary disease
30
dementia
30
carcinoid syndrome
30
conjunctiva
29
PAF
29
sudden infant death syndrome
29
more...
Symptom
pain
1787
analgesia
236
vomiting
167
cough
144
anesthesia
127
headache
121
diarrhea
86
nausea and vomiting
84
Welt
69
seizures
66
constipation
60
nausea
41
acute pain
36
erythema
33
hypercapnia
30
abdominal pain
30
sneezing
29
flushing
29
low back pain
27
back pain
23
spasm
23
retching
20
discomfort
20
Neuropathic pain
20
discomfort
20
functional recovery
20
fatigue
18
acute stress
18
dystonia
17
hypothermia
17
myalgia
17
arthralgia
16
dyspnea
16
angina
16
anorexia
16
rhinorrhea
16
Deafferentation
16
pelvic pain
14
spasticity
12
hyperoxia
11
chronic cough
11
starvation
11
hunger
11
acidity
10
ataxia
10
cancer pain
10
respiratory distress
10
chorea
10
neuralgia
10
dental pain
10
agitation
9
exhaustion
9
chronic constipation
9
nasal congestion
9
urinary frequency
8
orofacial pain
8
tachypnea
8
bladder pain
8
twitching
8
dry eye
8
weakness
7
facial pain
7
insomnia
7
bradykinesia
6
skin irritation
6
bone pain
6
shoulder pain
5
neck pain
5
knee pain
5
numbness
5
Ill
5
distraction
5
wheezing
5
Visceral pain
5
collapse
5
sleepiness
4
hyperesthesia
4
dysesthesia
4
polydipsia
4
apathy
4
more...
Drug
Dermatol
222
Atropine
131
Histamine
116
Cardiovasc
85
CSF
76
Indomethacin
68
lysine
65
nitroglycerin
64
Nephron
63
Asn
53
citric acid
49
IFN-gamma
49
Aprepitant
47
Phosphoramidon
44
IL-2
38
caffeine
38
ICI
33
Biopolymers
33
Gel
30
Captopril
28
Angiotensin II
28
MAP
23
Clonidine
22
Asthma
19
Sodium nitroprusside
18
Glucagon
17
DHT
17
DHT
17
p75
17
ascorbate
16
Monit
16
ETA
16
Forskolin
15
TAK
15
HCH
15
CTX
15
CaCl2
13
CaCl2
13
CaCl2
13
GRF
13
Secretin
12
Phentolamine
11
Ethanol
11
Leaf
11
Guanethidine
11
Citric acid
10
CTX
10
Theophylline
10
CTX
10
ISP
10
PCP
10
Raloxifene
9
Apomorphine
9
Kainic acid
8
ABC
8
Ringer's solution
8
Nedocromil sodium
8
Allergen
8
Nitric Oxide
8
ROS
7
Scopolamine
7
NH3
7
Pregabalin
7
Adenosine triphosphate
7
PTH
7
BoNT/A
7
Ketotifen
7
Salbutamol
6
Fluorescein
6
vitamin E
6
DFP
6
Reserpine
6
GHRP
6
Methylene blue
6
Diphenhydramine
6
Tubocurarine
6
NADH
6
Paraffin
6
Pilocarpine
5
Propofol
5
more...
Enzyme
tyrosine hydroxylase
677
CD10
480
peroxidase
428
choline acetyltransferase
326
protein kinase C
262
acetylcholinesterase
244
NO synthase
178
adenylate cyclase
178
phospholipase C
155
ACE
149
mitogen-activated protein kinase
146
protein kinase
137
ERK
127
NADPH-diaphorase
120
trypsin
119
renin
78
superoxide dismutase
67
dopamine beta-hydroxylase
67
tryptase
67
collagenase
58
ATPase
56
acid phosphatase
55
guanylate cyclase
55
NOS
53
diaphorase
52
phospholipase A2
52
diaphorase
52
NQO1
52
phosphodiesterase
51
prolyl endopeptidase
44
chymotrypsin
43
thrombin
42
catalase
41
glutamate decarboxylase
41
lipoxygenase
41
dipeptidyl peptidase IV
39
reverse transcriptase
38
cholinesterase
37
enolase
36
alkaline phosphatase
35
chymase
31
caspase-3
30
CD13
28
tryptophan hydroxylase
28
monoamine oxidase
27
MEK
26
kallikrein
26
luciferase
24
RNA polymerase
20
lactate dehydrogenase
19
urease
18
urease
18
focal adhesion kinase
18
ACS
17
cytochrome oxidase
17
calcineurin
17
lysozyme
17
botulinum neurotoxin
17
RNase
17
neuraminidase
15
carbonic anhydrase
15
MIP
15
transglutaminase
15
RNase
15
transcriptase
14
hyaluronidase
14
aspartate aminotransferase
14
hyaluronidase
13
beta-galactosidase
13
MMP-3
13
hexosaminidase
13
endothelin-converting enzyme
13
tissue plasminogen activator
13
NADPH oxidase
13
pepsin
12
adenosine deaminase
12
adenosine deaminase
12
aminopeptidase P
12
MAP
12
NADPH oxidase
12
more...
Compound
Substance P
3231
Dec
1538
calcium
1337
methionine
972
arginine
719
nitric oxide
666
glutamate
640
5-HT
622
sodium
621
leucine
606
noradrenaline
555
water
541
potassium
489
Phe
489
Capsaicin
470
Clin
468
GABA
425
GABA
417
nitrogen
319
ATP
317
Gly
308
tyrosine
304
NH2
281
lysine
271
phosphate
268
His
248
gamma-aminobutyric acid
246
Calcitonin
213
cAMP
207
ACh
205
alanine
200
DNA
184
oxygen
184
phosphorus
177
NMDA
169
Ile
168
acetate
162
AMP
156
Atropine
131
glucose
131
ACTH
129
cGMP
128
Bradykinin
127
Asp
126
ethanol
125
acetic acid
123
salt
119
TNF
119
Histamine
116
isoleucine
114
isoleucine
114
sulfate
113
silver
111
hydrogen
101
Neurotensin
91
proline
90
Morphine
90
zinc
90
PGE2
89
serine
87
CO2
86
GTP
83
Neuronal
80
threonine
80
prostacyclin
79
TRH
77
tryptophan
74
Naloxone
73
Tetrodotoxin
73
AMPA
66
Indomethacin
66
HCl
65
nitrate
65
benzamide
64
ammonium
62
Mg2+
62
Norepinephrine
60
formaldehyde
59
Dopamine
59
PGE
58
more...