Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20366 (substance P)
 21,176 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cross-reaction of a rat monoclonal antibody (BTP-1) against seventeen substance P analogues was studied. The antibody was of IgG type and related to the carboxyl terminal of substance P, especially methionyl in the terminal, but did not depend on the strength of antagonistic effects of these analogues. It did not show cross-reaction with the following nine peptides: glucagon, endorphin, angiotensin I, II, leucine-enkephalin, methionine-enkephalin, bradykinin, oxytocin and dernorthin, indicating its high specificity to substance P. By means of immuno-enzyme histochemical method, it was shown that stained nerve fibers were located in the gelaliternous substance of Rolando, interpeduncular nucleus, substantia nigra and nerve cell bodies in the vestibular nucleus, lateral tegmental nucleus of mesencephalon and ventral region of third ventricle.
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PMID:[Study of characteristics of monoclonal antibody against substance P]. 169 64

The survival, biomass production and copper (Cu) remediation efficiency of Jatropha curcas L. was evaluated in Cu rich industrial wasteland soil (IWLS), collected from a local town, Sandila (Hardoi), Uttar Pradesh, India. The IWLS had high bulk density, water holding capacity (WHC), pH, electrical conductivity (EC), organic carbon and NPK. The Cu and Mn contents in IWLS were about 3 and 2 fold higher than that in the normal field soil (control). Stem cuttings of the J. curcas clones (BTP-A, BTP-N and BTP-K) were planted in IWLS as well as the same amended with cowdung or sand. The percent survival, net elongations and biomass accumulation of J. curcas were decreased slightly in IWLS, as compared to the control soil. The translocation of Cu from soil to the plants was higher in IWLS grown plants, which was more pronounced in IWLS amended with cowdung. J. curcas clones BTP-N, showed better survival and Cu removal efficiency from IWLS.
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PMID:Growth, biomass production and remediation of copper contamination by Jatropha curcas plant in industrial wasteland soil. 2303 82