Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P20366 (
substance P
)
21,176
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
[3H]CP-96.345 with the specific radioactivity of 84.2 Ci/mmol has been prepared from CP-96.345 by the high-temperature solid state isotopic exchange. The tritiated compound was equipotent with the parent antagonist in inhibiting the iodinated
substance P
binding to brain membranes from various species. Direct binding of [3H]CP-96.345 was detected by radioligand analysis using the
striatum-enriched
membranes from the guinea-pig brain.
...
PMID:[Preparation and characteristics of a tritiated derivative of CP-96,345--a nonpeptide antagonist of the substance P receptor with a high specific radioactivity]. 788 Jan 76
