Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20366 (substance P)
 21,176 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of pilocarpine and substance P on the amplitudes of the postganglionic compound action potentials (unconditioned response, UR and post-train conditioned response, PTR) were studied in the isolated rabbit superior cervical ganglion (SCG). Pilocarpine (50 microM) and substance P (1 microM) produced an increase in the amplitudes of both UR & PTR responses in the rabbit SCG. Facilitation and subliminal fringe values decreased. It was concluded that both pilocarpine and substance P increase the amplitudes of the transmitted postganglionic compound action potentials and they may facilitate ganglionic transmission in the rabbit SCG.
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PMID:Effect of pilocarpine and substance P on ganglionic transmission. 619 38