Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20226 (TATA-binding protein)
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Human Gene/Protein
TBP-associated factor 172 14.6
TATA-binding protein 14.6
BTAF1 protein 14.6
BRFU 14.2
TFIIIB90 13.9
hTAFII55 13.9
TAFI48 13.8
TAFI110 13.6
TAF9L 13.6
TBP protein 13.6
TFIIA-gamma 13.6
H3 histone, family 3A 13.6
HTEX4 13.6
60S ribosomal protein L23 13.6
transcription factor-like nuclear regulator 13.6
transmembrane protein 79 13.6
TAFI63 13.6
Suppressor of cytokine signaling 6 13.6
hTAFII100 13.6
BTAF1 13.5
Transcription factor IIB 13.4
activator of basal transcription 1 13.3
TBP-associated factor 13.2
TAF13 13.2
TAF8 13.2
TAF(II)135 13.0
TBP-associated factor 11 13.0
Heterogeneous nuclear ribonucleoprotein F 13.0
TAF(II)30 12.8
TAF9 12.8
TAFII55 12.8
transcription factor IID 12.7
ZNF76 12.7
TBP-interacting protein 12.7
TAF2 12.7
TFIIA 12.7
MOT1 12.6
BRP44L 12.6
TAF11 12.6
SNAP19 12.6
more...
Disease
SCA17 12.5
Gopalan 10.9
HPC4 10.7
Vaccinia virus infection 10.5
IDDM8 10.5
HDL1 9.7
TALS 9.7
SCA8 9.7
Hughes syndrome 9.3
SCA12 9.2
XDP 9.2
Spinocerebellar ataxia 8.8
SCA7 8.6
CAA 8.4
FRDA 8.2
SCA1 8.0
SCA2 8.0
CAA 7.9
XPB 7.2
AD2 7.1
Machado-Joseph disease 7.1
CLN2 7.0
FTLD 7.0
SCA6 6.9
primary lateral sclerosis 6.9
FUS 6.7
AD1 6.7
TEC 6.5
HDL2 6.5
Bateman 6.3
CLN1 6.3
Recruitment 6.1
Forbes 6.1
MSS 6.0
HDL3 5.9
XPD 5.8
hemophilia B 5.8
bends 5.8
Frontotemporal dementia 5.7
torsion dystonia 5.7
more...
Symptom
Extrapyramidal symptoms 7.0
chorea 6.4
cerebellar ataxia 5.8
clumsiness 5.5
dystonia 5.5
ataxia 5.3
bradykinesia 5.0
incoordination 3.8
dysarthria 3.7
cachexia 2.1
starvation 2.0
spasticity 1.9
tremor 1.4
hypothermia 0.5
collapse -0.2
seizures -0.7
pain -3.4
Drug
Tora 9.8
K201 9.5
CDX 6.6
CDX 6.2
DNase I 5.9
CIA 5.0
Etoposide 4.4
ETS 4.2
Alanine 4.1
CTA 4.1
Glycyrrhiza 4.1
VCR 4.0
Ranitidine 3.9
-deoxyadenosine 3.6
Gel 3.5
Capsicum 3.4
Glycerol 3.4
Fraction 3.3
MOF 3.0
lysine 3.0
p75 2.7
Adriamycin 2.4
ICI 2.2
FAD 2.2
Ethanol 1.3
Asn 1.1
CSF 0.7
ROS 0.3
caffeine 0.2
IL-2 -0.2
Enzyme
arginyltransferase 9.0
KLK13 8.8
RNA polymerase 8.3
3C protease 8.2
SPT 8.1
histone acetyltransferase 7.9
CTD kinase 7.5
conjugase 7.4
macrophage elastase 7.4
SPT 7.4
methyl coenzyme M reductase 7.2
lambda exonuclease 6.9
pantothenate kinase 6.6
ADH3 6.6
succinic semialdehyde dehydrogenase 6.4
restriction-modification system 6.1
factor D 5.8
O-GlcNAc transferase 5.6
asparagine synthetase 5.6
glyceraldehyde-3-phosphate dehydrogenase 5.5
glyceraldehyde-3-phosphate dehydrogenase 5.5
glyceraldehyde-3-phosphate dehydrogenase 5.4
glyceraldehyde-3-phosphate dehydrogenase 5.4
MTD 5.4
porphobilinogen deaminase 5.3
glyceraldehyde-3-phosphate dehydrogenase 5.2
poly(A) polymerase 5.2
insulin-degrading enzyme 5.1
aldehyde dehydrogenase 4.9
PAT 4.9
tryptophan 2,3-dioxygenase 4.8
sucrase-isomaltase 4.8
KAT 4.8
ALA synthase 4.6
farnesyltransferase 4.6
carboxypeptidase Y 4.2
DNA ligase 4.2
DNA ligase 4.2
micrococcal nuclease 4.1
farnesyltransferase 4.0
more...
Compound
TBP 10.8
TBP 10.6
TIF 10.1
alpha-Amanitin 8.4
CAA 8.3
TPB 8.2
Molybdenum cofactor 8.2
Nile Blue 7.5
Nile Blue 7.5
ATF 6.8
MGBG 6.6
MGBG 6.6
TEC 6.5
AF-2 6.5
TFE 6.4
Carcinogen 6.4
TET 6.2
TET 6.2
Benzo[a]pyrene 6.1
SP-1 5.8
[1,10]phenanthroline 5.6
Camptothecin 5.4
Camptothecin 5.4
Camptothecin 5.4
DBD 5.3
dUMP 5.2
DAB 5.2
TAR 5.1
glutamine 5.0
Polyamine 5.0
pteridine 5.0
PAT 5.0
DMS 4.9
Histone 4.9
LCR 4.9
AICAR 4.9
MAD 4.9
AAT 4.8
CAN 4.8
NBQX 4.7
more...