Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20020 (adenosine triphosphatase)
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Human Gene/Protein
adenosine triphosphatase 13.2
EH domain containing 2 13.2
anaphase-promoting complex subunit 5 13.2
CCDC49 13.2
C7orf28A 13.2
ras related gene 12.2
FLJ10374 11.7
pyruvate dehydrogenase (lipoamide) beta 11.2
Myokinase 10.7
ATP13A1 10.4
AGPAT5 10.4
vasopressin-neurophysin precursor 10.4
Myosin light chain 1 10.2
DNAJ homolog 10.2
VPS37B 10.1
Swc2 10.1
EH domain-binding protein 1 10.1
BCD1 10.1
Transmembrane protein 192 9.9
phosphorylase, glycogen 9.8
ATP2B1 9.7
ZNHIT3 9.7
CHMP3 9.7
HNRNPH2 9.5
channel-inducing factor 9.5
Na+,K+ ATPase 9.5
KIF27 9.4
PRP28 9.4
hCTR2 9.4
Succinic dehydrogenase 9.4
CHMP2A 9.3
Gonadotropin-regulated testicular RNA helicase 9.3
DENND5A 9.3
ATP6V1C1 9.3
Tat-binding protein-1 9.3
ATP12A 9.2
ATAD1 9.2
CHMP6 9.2
UBXD1 9.2
RIOK1 9.1
SOS2 protein 9.1
ATP6V0D2 9.1
SLC5A6 9.1
EHBP1 9.1
CARD-containing protein 9.1
MLCK protein 9.1
ATP7B protein 9.1
CD39L1 9.1
inositol hexakisphosphate kinase 1 9.1
NDUFA10 9.1
FXYD7 9.1
serum and glucocorticoid regulated kinase 9.0
PMCA3 8.9
calcium binding and coiled-coil domain 2 8.9
ATP6L 8.9
Nicotinamide mononucleotide adenylyltransferase 1 8.8
DBP1 8.8
Vma21p 8.8
PEX26 8.8
NUFIP1 8.8
sodium-potassium-chloride cotransporter 8.7
ATPase mRNA 8.7
MSL-1 8.7
ENaCalpha 8.7
MyHC-2x 8.7
mitochondrial ATPase 8.7
PMCA1 8.7
SMVT 8.7
OS9 8.7
inosine triphosphatase 8.6
VPS4 8.6
Hsp70 interacting protein 8.6
DDX25 8.6
MAGOH 8.5
MyHC-IIa 8.5
TIRC7 8.5
ATPase subunit 8 8.5
GLP-2R 8.5
KIFC3 8.5
5' nucleotidase 8.5
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Disease
Chronic serous otitis media 12.2
Hyponatremic encephalopathy 10.7
Morgagnian cataract 9.9
water clefts 9.7
Hoffmann's syndrome 9.7
GACI 9.4
congenital neuromuscular disorder 9.2
glycopenia 8.8
Mononeuritis multiplex 8.5
IBMPFD 7.7
Posterior capsule opacification 7.7
hypothyroid myopathy 7.2
NPHP3 7.0
Oropharyngeal dysphagia 7.0
NML 7.0
Epididymis 7.0
Epididymis 7.0
Distal renal tubular acidosis 7.0
Pulmonary congestion 6.8
glomangioma 6.6
Acute myocardial ischemia 6.6
gastric mucosal atrophy 6.6
luteoma 6.6
alcoholic myopathy 6.5
Acute heart failure 6.5
preexcitation syndrome 6.5
Klebs 6.5
cardiac overload 6.5
TYPE 6.4
NNH 6.4
lgl 6.4
Zollinger-Ellison syndrome 6.4
Pancreatic duct 6.3
MacLeod 6.2
Jejunum 6.1
early disease onset 6.1
Transient ischemia 6.0
Familial hemiplegic migraine 6.0
FRA 6.0
RAT 6.0
lymphoblastoma 5.9
SPG4 5.8
Robinow syndrome 5.7
Goldblatt hypertension 5.6
Kartagener's syndrome 5.6
myocardial hypoxia 5.5
Leigh syndrome 5.5
diabetic cataract 5.5
Acute infection 5.4
periodic paralysis 5.4
head cancer 5.4
IS2 5.4
parasympathomimetic 5.3
Brodie 5.3
AAA 5.3
GRTH 5.2
Letterer-Siwe disease 5.2
complete paraplegia 5.1
renal papillary necrosis 5.1
hemiplegic migraine 5.1
pernicious anemia 5.1
Mitchell 5.0
beryllium disease 5.0
reflux esophagitis 5.0
Wilson's disease 5.0
ventricular failure 5.0
audiogenic seizure 4.9
Farber 4.9
immunocytoma 4.9
Zenker's diverticulum 4.9
Myoepithelial 4.9
XPB 4.9
sprue 4.9
hepatic neoplasm 4.8
WSN 4.8
WSN 4.8
Menkes 4.8
Bielschowsky 4.7
ear disease 4.7
Crabs 4.7
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Symptom
Fatigability 7.3
elevated mood 6.5
asterixis 5.5
labored breathing 5.5
loss of taste 4.7
Decreased activity 4.2
Anoxia 4.1
twitching 3.8
clubbing 3.4
muscle cramps 3.4
heartburn 3.2
Mills 2.9
polyuria 2.7
despair 2.6
torticollis 2.6
fatigue 2.5
epigastric pain 2.5
starvation 2.4
cerebellar ataxia 2.4
dysarthria 2.4
acidity 2.3
blurred vision 2.2
polydipsia 2.1
hypothermia 2.0
lethargy 1.8
HSA 1.7
ophthalmoplegia 1.5
functional recovery 1.5
exhaustion 1.5
weakness 1.2
anorexia 1.1
tremor 1.1
respiratory distress 1.0
constipation 0.9
diarrhea 0.9
ataxia 0.9
thinning 0.8
hemoptysis 0.7
spasticity 0.6
dystonia 0.2
anesthesia 0.1
distraction 0.0
low back pain -0.0
seizures -0.1
nausea -0.3
stigma -0.5
collapse -0.6
vomiting -0.7
angina -1.1
discomfort -1.2
discomfort -1.3
dyspnea -1.5
headache -1.5
abdominal pain -1.7
pain -2.0
Drug
Atractylodes rhizome 9.1
Atabrine 8.9
Hetrazan 8.7
Adenyl 8.6
Ouabain 8.3
Perhexiline 7.4
Tritiated water 7.0
Omeprazole 7.0
Adenosine triphosphate 6.7
Enoximone 6.2
Podophyllotoxin 6.1
Bumetanide 6.1
Fenbendazole 5.9
Amiloride 5.8
Dronedarone 5.8
Amiloride 5.6
Ethane 5.5
Monensin 5.3
Pyridoxal 5.2
RbCl 5.2
RbCl 5.2
Epoetin 5.2
Guanethidine 5.1
Lactase 5.1
NADH 5.0
Epoetin alfa 5.0
Levosimendan 5.0
Digitalis 5.0
CPZ 4.9
Guanidine 4.9
Guanidine 4.8
K-252a 4.8
SMP 4.7
Phentolamine 4.6
Hyaluronidase 4.4
Emodin 4.3
Hyaluronidase 4.3
Reserpine 4.3
Dihydro 4.2
Troglitazone 4.2
Clofibrate 4.1
CED 4.1
Emodin 4.1
Metrizamide 4.0
CaCl2 3.9
CaCl2 3.9
CaCl2 3.9
Rutin 3.9
Phenytoin 3.9
Secretin 3.7
Cimetidine 3.6
Acacia 3.6
Cimetidine 3.5
Atenolol 3.5
SF6 3.5
Ethanol 3.4
Fluorescein 3.4
NaI 3.4
NaI 3.4
NaI 3.4
NaI 3.4
Methylprednisolone 3.4
DFP 3.4
Parkin 3.4
Parkin 3.4
Ringer's solution 3.4
Galactose 3.2
Hypaque 3.1
Histamine 3.1
Captopril 3.1
AMC 3.0
TAT 3.0
Hypaque 3.0
Fluorescein 2.9
Vitamin B 2.9
Indomethacin 2.9
Methylene blue 2.9
Fraction 2.9
Lovastatin 2.9
Glutathione 2.8
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Enzyme
EC 3.6.3.9 10.4
energy-linked transhydrogenase 9.8
p-nitrophenylphosphatase 9.6
ATPase 8.9
succinic dehydrogenase 8.8
beta-glycerophosphatase 8.5
ADPase 8.3
triphosphatase 8.3
glucose-6-phosphatase 8.2
H,K-ATPase 8.2
proton-translocating ATPase 8.1
5'-nucleotidase 8.0
transhydrogenase 7.9
nucleotidase 7.9
nicotinamide adenine dinucleotide glycohydrolase 7.9
succinate dehydrogenase 7.9
DHOdehase 7.8
Mg2+-ATPase 7.7
glycerol-3-phosphate dehydrogenase 7.7
glycerol-3-phosphate dehydrogenase 7.7
myosin ATPase 7.7
inosine triphosphatase 7.5
trimetaphosphatase 7.5
GPH 7.5
GP-I 7.4
calcium pump 7.3
dynein ATPase 7.2
beta-hydroxybutyrate dehydrogenase 7.0
glyoxylate reductase 7.0
acid phosphatase 6.9
glyoxylate reductase 6.9
nucleoside diphosphokinase 6.9
pyruvate dehydrogenase phosphatase 6.8
glycerol-3-phosphate oxidase 6.6
leucine aminopeptidase 6.5
polyphosphatase 6.4
apyrase 6.2
ATP synthase 6.2
EC 3.6.1.1 6.1
arginyl-tRNA synthetase 6.1
diaphorase 6.1
ATP diphosphohydrolase 6.0
gamma-glutamyl transpeptidase 5.9
protein disulfide-isomerase 5.9
glycine amidinotransferase 5.9
diaphorase 5.9
adenylate kinase 5.9
NADH dehydrogenase 5.9
phosphorylase 5.9
oxaloacetate decarboxylase 5.9
ubiquinol-cytochrome c oxidoreductase 5.8
DD-carboxypeptidase 5.8
exopolyphosphatase 5.8
hydroxypyruvate reductase 5.8
polynucleotide phosphorylase 5.7
glucose-6-phosphate dehydrogenase 5.7
glutamyl-tRNA synthetase 5.7
nucleotide pyrophosphatase 5.7
phosphoglyceromutase 5.6
hydroxypyruvate reductase 5.6
phosphatidylserine decarboxylase 5.6
alkaline phosphatase 5.6
glycerol 3-phosphate dehydrogenase 5.6
fumarate reductase 5.5
malate dehydrogenase 5.5
NAD+ oxidoreductase 5.5
NADPH-diaphorase 5.5
glutamic dehydrogenase 5.4
PDH 5.4
polyphosphate kinase 5.4
acylphosphatase 5.4
hexokinase 5.3
DD-carboxypeptidase 5.3
cytochrome oxidase 5.2
isocitrate dehydrogenase 5.1
fumarase 5.1
iodothyronine 5'-deiodinase 5.1
isocitrate dehydrogenase 5.1
6-phosphogluconate dehydrogenase 5.1
6-phosphogluconate dehydrogenase 5.1
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Compound
Reserpic acid 12.2
1-ethyl-1,2,3,4-tetrahydroquinoline 12.2
2-Bromoethylamine hydrobromide 10.7
2-Bromoethylamine hydrobromide 10.7
Thiobencarb 10.1
Citreoviridin 9.5
Oligomycin A 9.4
Sodium glycocholate 9.3
Isoprothiolane 9.1
Cytochalasin A 8.9
Rubratoxin B 8.8
SQ 20009 8.8
Canrenone 8.6
Methyl isocyanate 8.6
Tentoxin 8.5
Ouabain 8.3
Phenamil 8.1
S 10 8.0
Veratrine 8.0
Diethylcarbamazine citrate 8.0
Adrenochrome 8.0
Brusatol 8.0
methyl propiolate 7.8
Sodium orthovanadate 7.8
Pantoprazole 7.7
Lansoprazole 7.7
Copper chloride 7.7
Strophanthidin 7.6
GMDP 7.6
Beryllium 7.5
Sodium vanadate 7.5
cinnamyl acetate 7.5
CeCl3 7.4
Rabeprazole 7.3
Kryptofix 2.2 7.3
22R-hydroxycholesterol 7.2
1-nonanol 7.2
Erythrosin 7.1
Acetyl phosphate 7.1
Atractyloside 7.1
Ethacrynic acid 7.1
Adenine arabinoside 7.0
DCC 7.0
Bufalin 7.0
D-Galactosamine 6.9
2,4-dibromophenol 6.9
Azaserine 6.8
Cilag 6.8
Ethacrynic acid 6.8
Omeprazole 6.7
Emetine 6.7
HEDTA 6.7
1,3,5-hexatriene 6.7
1,3,5-hexatriene 6.7
1,3,5-hexatriene 6.7
Encainide 6.6
Valinomycin 6.6
O6-Methylguanine 6.6
BTL 6.6
PBZ 6.6
Bepridil 6.6
TCTP 6.5
Aloe-emodin 6.5
suberic acid 6.5
Combretastatin 6.5
NNN 6.4
4-chlorobenzyl 6.4
2-octanol 6.3
DMU 6.3
Oxymatrine 6.2
S-allylcysteine 6.2
sedoheptulose 7-phosphate 6.2
Podophyllotoxin 6.2
2,6-DNT 6.2
N-methylnicotinamide 6.2
Podophyllotoxin 6.2
Mg2+ 6.1
Triiodothyronine 6.1
Iodoacetamide 6.1
Biochanin A 6.1
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