Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P20020 (adenosine triphosphatase)
3,299 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of preventive and therapeutical function of Chinese herbs compound prescription Jian-Pi Yi-qi Li-Shui decoction (JPYQLSD) on cisplatin (DDP) and nephrotoxicity of rat. It was carried out that the prescription JPYQLSD had notable result in reducing content of serum urea nitrogen, glucosaminidase, beta 2-microglobulin of the rats (P < 0.05). JPYQLSD also could alleviate inhibition on activity of adenosine triphosphatase (ATP-ase). Pathological examination revealed the protective effect of the JPYQLSD on kidneys of rats. It suggested that JPYQLSD has a good effect on preventive and therapeutical function of Cisplatin (DDP) nephrotoxicity. The mechanism of JPYQLSD was to regulate the energy metabolism of rats.
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PMID:[Effect of preventive and therapeutical function of jian-pi yi-qi li-shui decoction on cisplatin nephrotoxicity in rats]. 133 69