Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P17174 (aspartate aminotransferase)
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Human Gene/Protein
aspartate aminotransferase 11.1
natural killer cell receptor 2B4 11.1
ubiquitin-conjugating enzyme E2Z 11.1
Chloride intracellular channel protein 2 11.1
splicing factor arginine/serine-rich 6 11.1
transducin-like enhancer protein 11.1
LC27 10.5
alanine aminotransferase 10.1
GOT1L1 10.1
creatine kinase, mitochondrial 10.1
TPARL 10.1
mitochondrial glycerol 3-phosphate acyltransferase 10.1
Cell death activator 10.1
AAT1 9.8
C6orf120 9.5
SSB3 9.5
SET nuclear oncogene 9.5
Erbb2 interacting protein 9.5
Alanine aminotransferase 9.4
glutamate pyruvate transaminase 9.1
SID1 transmembrane family member 2 9.1
CTXL 9.1
CCBL2 9.1
AD031 9.1
GPT2 8.9
AAT-1 8.8
Aspartate aminotransferase 8.8
myristoyl CoA:protein N-myristoyltransferase 8.7
gamma-glutamyltransferase 8.6
ST6GALNAC3 8.5
GP110 8.5
Gamma-glutamyltransferase 8.5
aat-1 8.5
aspartate dehydrogenase 8.4
myosin light chain 3 8.4
SAMM50 8.3
dihydrolipoamide S-succinyltransferase 8.3
LDHL 8.3
Nucleoside diphosphokinase 8.3
TRIM40 8.3
MP100 8.2
zinc transporter 5 8.1
Alanine-glyoxylate aminotransferase 8.1
paraoxonase-3 8.1
PPP1R3G 8.1
GLT25D1 8.1
PARVB 8.1
sorbitol dehydrogenase 7.9
CCBL1 7.9
SDR1 7.9
M/SCHAD 7.9
Aspartate transaminase 7.9
H(+)-transporting ATP synthase 7.9
FABPpm 7.9
GOT1 7.8
HS3ST3B1 7.7
NACB 7.7
Transcobalamin I 7.7
gamma-glutamyl transpeptidase 7.7
Ornithine aminotransferase 7.7
cytochrome b-5 7.6
AST 7.6
glutamate dehydrogenase 7.6
lactate dehydrogenase 7.5
ASAT 7.5
NCALD 7.5
Alpha-mannosidase 7.5
GST-III 7.5
UGT2B28 7.5
indolethylamine N-methyltransferase 7.5
aryl hydrocarbon receptor nuclear translocator 2 7.5
C2GnT-M 7.5
GPX4 protein 7.5
aspartate aminotransferase 1 7.5
cytochrome P450 2E1 7.5
creatine kinase 7.4
glutathione S-transferase A1 7.4
NR1I1 7.4
collagen alpha 2(I) 7.4
fructose-bisphosphate aldolase C 7.4
more...
Disease
cardiopericarditis 11.1
Midzonal hepatic necrosis 11.1
AAT5 10.6
Cytomegalovirus syndrome 10.1
Pigment nephropathy 10.1
AAT2 9.9
AAT3 9.7
Exudative diathesis 9.5
Tying-up 9.1
Round heart disease 8.7
Erythrocytopenia 8.7
Estrogenic effect 8.7
mercaptolactate-cysteine disulfiduria 8.5
Compensated metabolic acidosis 8.5
Erythroid hypoplasia 8.5
Secondary biliary cirrhosis 8.5
Ischemic hepatitis 8.3
AAT1 8.3
Recurrent upper respiratory tract infections 8.3
Regenerative anemia 8.3
Acute toxic hepatitis 8.3
Boid inclusion body disease 8.3
Autoimmune hypothyroidism 7.9
Transient hypogammaglobulinemia of infancy 7.9
Jordan's anomaly 7.9
relapsed small lymphocytic lymphoma 7.9
Coronary artery anomaly 7.9
Carrion 7.9
Hepatic necrosis 7.9
Hepatotoxicity 7.8
Drug-induced myopathy 7.7
Corneal deposits 7.7
ASAT 7.6
Micronodular cirrhosis 7.6
Heartworm disease 7.6
Hepatic infarction 7.5
FAA4 7.5
MRSA wound infection 7.5
Myoglobinuric acute renal failure 7.5
Hepatic impairment 7.4
GTRAP3-18 7.4
Simian hemorrhagic fever 7.3
Toxicosis 7.2
Chronic iron overload 7.2
Intestinal coccidiosis 7.1
Hepatosplenic schistosomiasis 7.1
Chlamydia trachomatis pneumonia 7.1
Retinoic acid syndrome 7.1
GSD IX 7.0
heterophyiasis 7.0
Acute liver failure 6.9
vitamin B6 deficiency 6.9
PPD2 6.9
Alcoholic liver disease 6.9
liver fibrosis 6.8
Unconjugated hyperbilirubinemia 6.8
cholangiolitis 6.8
porcine stress syndrome 6.8
Cytokine storm 6.8
Conjugated hyperbilirubinemia 6.7
Acute hepatitis A 6.7
megalocytosis 6.7
Neuroinfections 6.7
cartilage disorder 6.7
Renal anemia 6.6
alcoholic psychosis 6.5
EBV hepatitis 6.5
acute alcoholism 6.5
Exertional rhabdomyolysis 6.5
IgG gammopathy 6.5
respiratory papillomas 6.4
Autoimmune liver disease 6.4
alcoholic fatty liver 6.3
FUSE 6.2
Nonalcoholic fatty liver 6.2
endophlebitis 6.2
Acute hepatitis E 6.1
Overlap syndrome 6.1
Reactive hemophagocytic syndrome 6.1
drug-induced hepatitis 6.1
more...
Symptom
jaundice of the skin 8.1
feeling sick 6.2
Murphy's sign 6.1
strangury 6.0
dark urine 5.7
frequent urination 5.6
hepatomegaly 5.2
hypoproteinemia 5.2
periorbital edema 5.1
bradypnea 5.0
right upper quadrant pain 5.0
emaciation 4.9
generalized rash 4.9
Muscle soreness 4.9
decreased appetite 4.5
lethargy 4.4
asterixis 4.4
anorexia 4.3
nocturnal cough 4.2
bigeminal 4.1
myalgia 4.0
loss of equilibrium 3.9
lassitude 3.9
chills 3.7
hepatosplenomegaly 3.7
Decreased activity 3.6
hangover 3.6
jaw pain 3.5
hyperemesis gravidarum 3.5
prostration 3.5
asthenia 3.5
impaired motor coordination 3.5
incoordination 3.4
polydipsia 3.4
rigors 3.4
splenomegaly 3.4
labored breathing 3.3
rales 3.3
nausea 3.3
Spots 3.2
oliguria 3.2
polyuria 3.2
hyperesthesia 3.0
body pain 3.0
muscle rigidity 3.0
ketonuria 3.0
vomiting 2.9
non-productive cough 2.9
excessive sweating 2.9
muscle cramps 2.8
muscle stiffness 2.8
arthralgia 2.8
No adverse effect 2.7
Psychiatric symptoms 2.7
loin pain 2.7
diarrhea 2.7
Physical findings 2.7
meningism 2.7
nasal discharge 2.7
epigastric pain 2.6
abdominal discomfort 2.6
sore throat 2.6
testicular pain 2.6
fatigue 2.6
nausea and vomiting 2.6
abdominal pain 2.6
pallor 2.6
tachypnea 2.6
Tenderness 2.5
flushing 2.5
nasal congestion 2.5
night sweats 2.4
intestinal bleeding 2.4
belching 2.4
bloating 2.4
livedo 2.3
skin irritation 2.3
overweight 2.3
loss of balance 2.2
colic 2.2
more...
Drug
Sulfopyruvate 9.7
Schisandra fruit 9.7
Somidobove 9.5
Gamma-Glutamylcysteine 9.5
Glibornuride 9.1
Erythromycin acistrate 8.7
Valerianae radix 8.3
Bidisomide 8.1
Propagermanium 8.1
Gemifloxacin mesylate 7.9
Dexamethasone palmitate 7.7
Monensin sodium 7.7
Cupric chloride 7.5
Sesame oil 7.3
Tocopherol acetate 7.3
pyridoxal phosphate 7.2
Zinga 7.2
Pyridoxal phosphate 7.1
Cupric sulfate 7.1
Citrus unshiu peel 7.0
Innohep 7.0
Tiopronin 7.0
Darapladib 6.7
Metreleptin 6.7
Pyridoxal 6.6
Mercurochrome 6.6
Cognex 6.5
Alendronate sodium 6.5
Tepoxalin 6.4
Uzel 6.4
Calciparine 6.4
Berberine chloride 6.3
Maduramicin 6.3
Pralatrexate 6.1
Manganese chloride 6.1
Menogaril 6.1
NAH 6.1
Tryptophane 6.1
Aescin 6.0
Questran 5.9
Lisdexamfetamine dimesylate 5.9
Histidinol 5.8
Sesamol 5.8
Bucillamine 5.8
Glucose-6-Phosphate 5.8
Vitamin B 5.8
Dipyrone 5.8
Peramivir 5.7
Estrumate 5.7
Swainsonine 5.7
Amlexanox 5.6
O-Acetylserine 5.6
Rocaltrol 5.6
Progabide 5.6
Clofarabine 5.5
Bosutinib 5.5
Zinc acetate 5.5
Swertia 5.5
Sivelestat 5.5
Benzofuran 5.5
1-Deoxynojirimycin 5.4
Rokitamycin 5.4
Lead acetate 5.3
Tulathromycin 5.3
Lenograstim 5.3
Aluminum chloride 5.3
Rompun 5.3
4-Hydroxytamoxifen 5.3
Parecoxib 5.3
Trapidil 5.2
Red ginseng 5.2
Coal tar 5.1
Dimethylformamide 5.1
Safflower 5.1
Nafcillin 5.1
Serum albumin 5.0
Kaletra 5.0
Cremophor RH40 4.9
Pyridoxamine 4.9
Abamectin 4.9
more...
Enzyme
aspartate-prephenate aminotransferase 11.1
glucose phosphomutase 11.1
aspartate aminotransferase 10.5
alanine aminotransferase 9.4
aromatic amino acid aminotransferase 9.4
CobD 9.3
succinyldiaminopimelate aminotransferase 9.1
D-amino acid aminotransferase 9.1
sulfopyruvate decarboxylase 8.7
histidinol phosphate aminotransferase 8.7
aspartate dehydrogenase 8.4
glutamine transaminase K 8.2
valine dehydrogenase 8.1
sorbitol dehydrogenase 7.8
gamma-glutamyl transpeptidase 7.8
pyruvate aldolase 7.7
2-oxoisovalerate dehydrogenase 7.7
ferric leghemoglobin reductase 7.7
guanosine deaminase 7.7
glutamate dehydrogenase 7.6
glutamate dehydrogenase 7.6
glutamate dehydrogenase 7.6
AST 7.6
EC 2.6.1.4 7.5
glutamic dehydrogenase 7.5
lactate dehydrogenase 7.5
transaminase C 7.4
pyridoxal oxidase 7.4
creatine kinase 7.3
EC 2.3.2.1 7.3
proprotein convertase 2 7.3
desulfinase 7.2
alkaline phosphatase 7.1
branched-chain aminotransferase 7.1
malate dehydrogenase 6.8
glutathione oxidase 6.7
collagen galactosyltransferase 6.7
alpha-aminoadipate aminotransferase 6.7
PrpD 6.6
guanase 6.5
arogenate dehydrogenase 6.5
glutathione peroxidase 6.4
tyrosine aminotransferase 6.4
threonine aldolase 6.4
glycine dehydrogenase 6.4
glycine dehydrogenase 6.4
EC 2.3.1.29 6.4
8-amino-7-oxononanoate synthase 6.3
4-nitrophenol hydroxylase 6.3
enzyme X 6.2
LGT 6.2
glutaminase 6.2
isocitrate dehydrogenase 6.2
tyrosine phenol-lyase 6.2
ornithine aminotransferase 6.1
transpeptidase 6.1
methylmalonate-semialdehyde dehydrogenase 6.1
phosphoserine aminotransferase 6.1
asparagine synthetase 6.0
delta-aminolevulinic acid dehydratase 6.0
glutathione reductase 6.0
selenocysteine lyase 5.9
dihydrolipoamide succinyltransferase 5.9
isocitrate dehydrogenase 5.9
octanol dehydrogenase 5.9
cysteine dioxygenase 5.8
threonine synthase 5.8
superoxide dismutase 5.8
lactic acid dehydrogenase 5.8
GABA transaminase 5.8
alpha-ketoglutarate dehydrogenase 5.8
glutamate synthase 5.8
fumarase 5.8
CSAD 5.8
6-phosphogluconate dehydrogenase 5.8
6-phosphogluconate dehydrogenase 5.8
alanine racemase 5.7
glutamate synthase 5.7
aldolase 5.7
glycine dehydrogenase 5.7
more...
Compound
2-amino-3-butenoic acid 11.1
(Benzamidooxy)acetic acid 11.1
Eremanthin 11.1
Perfluorosuccinate 11.1
Interferon gamma-1b 10.1
2-amino-4-methoxy-4-oxobutanoic acid 10.1
2-amino-4-methoxy-4-oxobutanoic acid 10.1
Coleonol 9.5
Diphenaldehyde 9.5
2-methylaspartic acid 9.5
Gostatin 9.5
Sequoyitol 9.5
Cupressuflavone 9.5
S-(2-aminoethyl)cysteine 9.3
S-(2-aminoethyl)cysteine 9.3
S-(2-aminoethyl)cysteine 9.3
Avenaciolide 9.1
4-methoxy-1-naphthaldehyde 9.1
Pachyman 9.1
Canaline 8.9
Fraxin 8.9
3-sulfopyruvate 8.9
3-chloroalanine 8.7
Robinin 8.7
Ophthalmic acid 8.7
Robinin 8.7
Sulfometuron methyl 8.7
C6H5NO3 8.7
3-phosphonoalanine 8.7
3-mercaptolactate-cysteine disulfide 8.7
3-chloroalanine 8.7
Pyridoxamine 5'-phosphate 8.6
4-methoxy-1-naphthaldehyde 8.5
Succinic acid monomethyl ester 8.5
arginine succinate 8.5
Pedunculagin 8.5
Taraxasterol 8.3
Lead nitrate 8.3
Columbin 8.3
Vicine 8.3
Dimethyl phosphate 8.3
(aminooxy)acetic acid 8.2
Citramalate 8.1
bicyclo[2.2.1]heptan-2-one 8.1
Cinobufotalin 8.1
Allyl methyl disulfide 8.1
Citramalate 8.1
Irisolidone 8.1
Tellimagrandin I 8.1
Dictamnine 8.0
Girinimbine 7.9
Trithion 7.9
alpha-Methyltryptophan 7.9
4-(diethylamino)benzaldehyde 7.9
1-phenyl-2-propen-1-one 7.9
Propagermanium 7.9
Karanjin 7.7
Diphenyl ditelluride 7.6
C5H9NO2 7.6
GDP-4-keto-6-deoxy-D-mannose 7.6
Diphenyl ditelluride 7.6
Fraxetin 7.6
Diphenyl diselenide 7.6
Prephenate 7.5
Yangonin 7.5
Chebulagic acid 7.5
Epoxiconazole 7.5
3-mercaptolactate 7.5
Chebulagic acid 7.5
CCl4 7.4
Lithospermic acid 7.4
Pyridoxine hydrochloride 7.4
Doxepin hydrochloride 7.4
D-Galactosamine 7.3
mercaptopyruvate 7.3
1H-indole-3-carbaldehyde 7.3
Diisodecyl phthalate 7.3
Yangonin 7.3
oxalacetate 7.2
PDAP 7.2
more...