Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P17174 (aspartate aminotransferase)
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Human Gene/Protein
aspartate aminotransferase 14872
alanine aminotransferase 6953
alkaline phosphatase 3149
lactate dehydrogenase 2219
superoxide dismutase 1470
albumin 1383
creatine kinase 1183
catalase 1096
Sep 1063
GSH 979
glutathione peroxidase 884
tumor necrosis factor 639
hemoglobin 593
TNF 568
Mol 564
AST 544
insulin 514
glutamate dehydrogenase 386
gamma-glutamyltransferase 353
lipopolysaccharide 352
caspase-3 326
IL-6 293
prothrombin 282
cytokine 280
collagen 277
C-reactive protein 274
glutathione reductase 272
glutamate pyruvate transaminase 261
gamma-glutamyl transpeptidase 258
interleukin-6 237
serum albumin 228
malate dehydrogenase 218
amylase 216
myeloperoxidase 215
HDL 210
galactosamine 206
inducible nitric oxide synthase 185
glutathione S-transferase 184
GTG 180
interferon 174
acid phosphatase 170
Alanine aminotransferase 168
Bcl-2 147
ATP 147
SOD 137
tumor necrosis factor alpha 125
antioxidant enzyme 125
IL-10 122
ferritin 121
GGT 120
heme oxygenase-1 116
sorbitol dehydrogenase 114
cytochrome P450 112
lipase 110
microsomal 109
TLR4 108
erythroid 108
LPS 106
surface antigen 103
gut 102
acetylcholinesterase 102
IFN 102
SMA 101
p65 100
LDH 98
smooth muscle actin 97
glutamine synthetase 96
isocitrate dehydrogenase 94
fibrinogen 92
glucose-6-phosphate dehydrogenase 92
TNF-alpha 89
FIB 88
endoplasmic reticulum 88
serum protein 88
thromboplastin 88
Aspartate aminotransferase 86
Nrf2 86
transferrin 85
myoglobin 83
NADH 81
lysozyme 79
NAD 79
She 76
peroxisome proliferator-activated receptor 76
NMR 76
CYP2E1 75
citrate synthase 74
cyclooxygenase-2 72
ALP 71
CD4 71
adiponectin 70
gamma-glutamyltranspeptidase 68
pyruvate kinase 68
fatty acid synthase 67
ATPase 66
cytochrome P450 2E1 66
GPT 65
p53 65
cytochrome 64
glutaminase 63
peroxidase 61
phosphoenolpyruvate carboxykinase 61
CAT 61
leptin 60
hexokinase 60
thymus 60
carp 59
reductase 59
haptoglobin 58
alpha-fetoprotein 58
JNK 58
p38 58
Alkaline phosphatase 58
Pol 57
glucose-6-phosphatase 57
xanthine oxidase 56
cytochrome P-450 56
proliferating cell nuclear antigen 56
alcohol dehydrogenase 56
cytochrome c 55
AAT 55
nitric oxide synthase 55
interleukin 6 54
AMP-activated protein kinase 54
dimeric 54
NADPH 53
Rec 53
TAT 51
NADP 50
A-I 50
PPAR 50
alpha-smooth muscle actin 49
IL-8 47
HO-1 47
HSP70 47
phosphatase 47
caspase-9 47
Creatine kinase 47
esterase 46
kit 46
metallothionein 45
ceruloplasmin 44
GST 43
ROS 43
MAPK 42
polypeptide 42
Albumin 42
lymphoid 41
CD8 41
interleukin-10 40
ASAT 40
IL-1 39
GABA 38
matrix metalloproteinase 38
IL-2 38
mTOR 38
AMPK 38
PI3K 38
6-phosphogluconate dehydrogenase 37
CO2 36
more...
Disease
GSH 979
liver disease 535
cancer 496
cirrhosis 488
hepatitis 457
ischemia 447
liver fibrosis 445
fatty liver 429
diabetes 412
tumor 376
hepatocellular carcinoma 346
chronic hepatitis 310
hepatitis B 300
hepatitis C 294
obesity 258
cholestasis 210
anemia 170
sepsis 163
cold 162
myocardial infarction 160
hypertension 160
sepsis 155
thrombocytopenia 145
alcoholic fatty liver 135
viral hepatitis 128
depression 126
type 2 diabetes 125
hyperlipidemia 117
Nonalcoholic fatty liver 117
chronic liver disease 116
acute myocardial infarction 110
metabolic syndrome 109
hyperglycemia 104
liver cancer 88
HIV 88
acute hepatitis 87
virus infection 84
alcoholism 83
rash 81
Hepatotoxicity 80
hypercholesterolemia 75
carcinoma 72
dyslipidemia 71
cardiovascular disease 70
myopathy 68
pneumonia 66
primary biliary cirrhosis 66
hypoglycemia 65
immunodeficiency 62
liver cancer 62
hyperbilirubinemia 61
pruritus 61
atherosclerosis 60
infectious diseases 59
neutropenia 58
alcohol abuse 57
breast cancer 57
myocardial ischemia 57
leukopenia 57
hepatitis A 55
dehydration 52
stroke 50
tuberculosis 49
heart failure 49
portal hypertension 49
cholangitis 48
B-cell lymphoma 48
renal failure 47
iron overload 46
malnutrition 45
tumor growth 44
chronic active hepatitis 43
carcinogenesis 43
lymphoma 43
AIDS 43
proteinuria 42
viremia 42
dengue 42
encephalopathy 41
Acute liver failure 41
renal disease 41
ASAT 40
rheumatoid arthritis 39
acute pancreatitis 39
SEM 38
periodontitis 38
plaque 38
hepatic encephalopathy 37
cytomegalovirus 37
adenocarcinoma 37
West 36
acute renal failure 36
pancreatitis 35
gallstones 35
lymphopenia 35
coagulopathy 35
biliary obstruction 33
cardiomyopathy 33
malaria 31
sickle cell disease 31
lymphadenopathy 30
thalassemia 30
preeclampsia 30
eosinophilia 29
alcoholic hepatitis 29
Hepatocellular carcinoma 29
schistosomiasis 29
metastases 28
epilepsy 28
leukemia 28
obstructive jaundice 27
coma 27
lung cancer 27
primary sclerosing cholangitis 27
arthritis 27
heart disease 26
glucose intolerance 26
influenza 26
fits 26
Alcoholic liver disease 25
coronary artery disease 25
Kawasaki disease 25
hypothyroidism 25
Infection 25
peritonitis 25
pulmonary edema 25
disseminated intravascular coagulation 25
ketosis 25
Cirrhosis 24
Epstein 24
alcoholic cirrhosis 24
SARS 24
acute myeloid leukemia 23
leishmaniasis 23
metabolic disorder 23
myositis 22
ash 22
uterus 22
periodontal disease 22
hyperinsulinemia 22
prostate cancer 21
Alzheimer's disease 21
AIN 21
colorectal cancer 21
Hodgkin's disease 21
lipidosis 21
hyperthyroidism 21
HCC 20
epididymis 20
worms 20
Pineal 20
melanoma 19
cholecystitis 19
Evans 19
hemorrhagic fever 18
lactic acidosis 18
AAT2 18
lymphocytosis 18
hemochromatosis 18
Brown 18
more...
Symptom
diarrhea 174
fatigue 146
anorexia 131
pain 130
vomiting 114
anesthesia 109
nausea 108
hepatomegaly 98
abdominal pain 87
weakness 70
overweight 59
lethargy 57
myalgia 48
cough 48
splenomegaly 48
dyspnea 48
seizures 47
headache 44
hypothermia 36
starvation 31
chest pain 31
nausea and vomiting 27
chills 26
respiratory distress 26
hepatosplenomegaly 26
collapse 24
ataxia 24
erythema 23
arthralgia 23
Ill 21
hypoproteinemia 19
constipation 18
flushing 17
exhaustion 17
emaciation 15
asthenia 14
polyuria 13
insomnia 12
decreased appetite 12
dizziness 11
polydipsia 11
back pain 10
right upper quadrant pain 10
epigastric pain 10
angina 10
analgesia 9
incoordination 9
sore throat 8
acute stress 8
tremor 8
discomfort 8
sleepiness 8
discomfort 8
oliguria 8
tachypnea 7
acidity 7
cachexia 7
dark urine 7
shortness of breath 7
pallor 7
paresis 7
colic 7
agitation 6
hypotonia 6
hyperoxia 6
functional recovery 6
apathy 5
abdominal discomfort 5
skin irritation 5
periorbital edema 4
frequent urination 4
nasal discharge 4
acute pain 4
muscle stiffness 4
rigors 4
exertional dyspnea 4
bloating 4
low back pain 4
muscle rigidity 4
HSA 3
regurgitation 3
bradypnea 3
hypercapnia 3
hyperemesis gravidarum 3
bone pain 3
thinning 3
night sweats 3
Decreased activity 3
rales 3
nasal congestion 3
muscle cramps 3
menopausal symptoms 3
blurred vision 3
Spots 2
fever of unknown origin 2
ketonuria 2
generalized rash 2
Wind 2
prostration 2
hemoptysis 2
acute abdominal pain 2
hoarseness 2
hunger 2
hyperesthesia 2
vertigo 2
livedo 2
stigma 2
hangover 2
acute abdomen 2
myoclonus 2
spasm 2
lassitude 2
twitching 2
cyanosis 2
asterixis 2
rhinorrhea 2
intestinal bleeding 2
Murphy's sign 2
dysuria 2
Muscle soreness 2
jaundice of the skin 2
dry skin 2
excessive sweating 2
memory loss 2
flank pain 1
loin pain 1
tingling 1
loss of equilibrium 1
knee pain 1
blackout 1
impaired motor coordination 1
neck stiffness 1
spasticity 1
neuralgia 1
consciousness disturbance 1
shoulder pain 1
labored breathing 1
distraction 1
hypocapnia 1
eds 1
POA 1
stomach pain 1
abdominal cramps 1
No adverse effect 1
nocturnal cough 1
Depressive symptoms 1
tenesmus 1
numbness 1
adenitis 1
clubbing 1
Psychiatric symptoms 1
body pain 1
Stiffness 1
dysarthria 1
stridor 1
despair 1
dystonia 1
syncope 1
paresthesia 1
anosmia 1
more...
Drug
vitamin E 192
pyridoxal phosphate 174
ascorbate 157
lysine 111
NADH 80
Ethanol 70
Cardiovasc 51
Monit 46
ROS 43
Albumin 42
IL-2 39
Glutathione 38
Vitamin B 32
Vitamin E 31
ROC 31
Portal 30
caffeine 27
IFN-gamma 27
ALA 27
CSF 26
citric acid 26
CTX 23
Alanine 23
Dermatol 21
niacin 20
Bifidobacterium 19
Serum albumin 19
Asn 19
Leaf 17
lactose 16
MAP 14
ZnO 14
Glycyrrhiza 13
Gel 13
Pyridoxal 12
Monensin 11
CTX 11
CTX 11
EE2 11
Isoniazid 10
Nephron 10
ENT 10
Dial 9
Fructose 9
Heme 9
Pyridoxal phosphate 9
Ginseng 9
NH3 9
Acacia 9
Rutin 8
TAK 8
CCL 8
Nephron 8
Norplant 8
Prednisolone 8
L-tyrosine 7
Tacrolimus 7
Ringer's solution 7
PCB 7
Isotretinoin 6
TiO2 6
Vitamin A 6
ampicillin 6
Adriamycin 6
FAD 6
Spectrum 6
EPA 6
Retinoic acid 6
Kenyan 6
DMI 6
Emodin 5
Sesame oil 5
ABC 5
Simvastatin 5
TAC 5
Biopolymers 5
CoCl2 5
Emodin 5
AZT 5
CoCl2 5
Infliximab 5
ETA 5
Swertia 5
Infliximab 5
Fraction 4
Fipronil 4
DNase I 4
Tiopronin 4
OTC 4
Aloe 4
NBT 4
Olive oil 4
Histamine 4
Trimethoprim-sulfamethoxazole 4
Fluorescein 4
Doxycycline 4
ACT 4
Captopril 4
Sodium valproate 4
Indocyanine green 4
NAH 4
Swainsonine 4
Bosentan 4
Clofibrate 4
MOF 4
Bosentan 4
Rosiglitazone 4
Ketoconazole 4
Bevacizumab 3
Capsicum 3
Arsenic trioxide 3
Glycerol 3
Pravastatin 3
AZT 3
RFP 3
Limonene 3
Valsartan 3
Honey 3
Lead acetate 3
MgSO4 3
Sesamol 3
Diphenhydramine 3
TAT 3
NAG 3
Aprotinin 3
IL-11 3
CTC 3
Parkin 3
DPA 3
Dipyrone 3
Gastro 3
ADM 3
Bayer 3
Clofarabine 3
ZnCl2 3
SBT 3
p75 3
Entecavir 3
PTH 3
Mutagen 3
Lovastatin 3
Parkin 3
ZnCl2 3
Entecavir 3
Nitric Oxide 3
THA 3
TTC 3
Mirtazapine 3
Levonorgestrel 3
Miltefosine 3
Exenatide 3
Caspofungin 2
Omeprazole 2
Etoposide 2
G-CSF 2
Vena 2
Herceptin 2
Nimesulide 2
Galactose 2
Scopolamine 2
more...
Enzyme
aspartate aminotransferase 14774
alanine aminotransferase 8708
alkaline phosphatase 3151
lactate dehydrogenase 2402
superoxide dismutase 1541
creatine kinase 1436
catalase 1134
gamma-glutamyl transpeptidase 956
glutathione peroxidase 898
AST 543
glutamate dehydrogenase 399
glutamate dehydrogenase 399
glutamate dehydrogenase 399
peroxidase 276
glutathione reductase 276
caspase-3 256
malate dehydrogenase 247
glutathione S-transferase 233
acetylcholinesterase 224
acid phosphatase 170
mitogen-activated protein kinase 166
cholinesterase 160
lipase 117
sorbitol dehydrogenase 115
glucose-6-phosphate dehydrogenase 110
isocitrate dehydrogenase 105
glutamine synthetase 96
isocitrate dehydrogenase 96
phosphoenolpyruvate carboxykinase 89
thromboplastin 89
protein kinase 89
phosphoenolpyruvate carboxykinase 88
aldolase 86
phosphoenolpyruvate carboxykinase 86
AMP-activated protein kinase 85
ATPase 84
lysozyme 80
citrate synthase 78
pyruvate kinase 69
glutaminase 65
ERK 62
succinate dehydrogenase 61
hexokinase 60
alcohol dehydrogenase 58
glucose-6-phosphatase 58
xanthine oxidase 57
tyrosine aminotransferase 53
trypsin 52
collagenase 50
transpeptidase 48
ceruloplasmin 45
arginase 42
focal adhesion kinase 41
AMPK 41
caspase-9 39
acetyl-CoA carboxylase 39
AMPK 38
6-phosphogluconate dehydrogenase 37
6-phosphogluconate dehydrogenase 37
pyruvate carboxylase 35
alpha-amylase 34
heme oxygenase 34
aldehyde dehydrogenase 33
NQO1 33
phosphoglucose isomerase 33
alpha-ketoglutarate dehydrogenase 33
demethylase 33
luciferase 31
glutamate decarboxylase 31
phosphoenolpyruvate carboxylase 30
beta-glucuronidase 30
pyruvate dehydrogenase 30
phosphoglucomutase 29
aromatic amino acid aminotransferase 29
cytochrome oxidase 29
fumarase 29
NO synthase 28
leucine aminopeptidase 28
reverse transcriptase 28
ornithine transcarbamylase 27
lipoprotein lipase 27
delta-aminolevulinic acid dehydratase 27
thrombin 26
phosphofructokinase 26
complex I 26
aldehyde dehydrogenase 25
CPT 25
5'-nucleotidase 24
ornithine aminotransferase 24
glucokinase 23
aldehyde dehydrogenase 23
aldehyde dehydrogenase 23
aldehyde dehydrogenase 23
adenosine deaminase 22
diaphorase 22
phosphorylase 22
gamma-glutamylcysteine synthetase 21
CPR 21
aconitase 21
pyruvate dehydrogenase 21
GABA transaminase 21
glyceraldehyde-3-phosphate dehydrogenase 21
pyruvate dehydrogenase 21
ECH 20
glutamate synthase 20
glutamate synthase 20
lactic acid dehydrogenase 20
transketolase 20
caspase-8 20
glutamic dehydrogenase 19
ACE 19
adenosine deaminase 19
UDP-glucuronosyltransferase 19
glutamate synthase 18
monoamine oxidase 18
protein kinase C 18
phospholipase A2 18
glyceraldehyde-3-phosphate dehydrogenase 17
PARP 17
carboxylesterase 17
CYP3A4 17
ACS 17
beta-galactosidase 17
type III procollagen 16
glyceraldehyde-3-phosphate dehydrogenase 15
GSK 15
branched-chain aminotransferase 15
paraoxonase 15
asparagine synthetase 15
adenylate kinase 15
hexosaminidase 15
phosphatidylinositol 3-kinase 14
renin 14
APC 14
glyceraldehyde-3-phosphate dehydrogenase 14
serine hydroxymethyltransferase 14
caspase-1 14
fructose 1,6-bisphosphatase 13
NADPH oxidase 13
nucleotidase 13
glyceraldehyde-3-phosphate dehydrogenase 13
chymotrypsin 12
ATP synthase 12
thymidine kinase 12
NOS 12
RNase 12
CPT 12
NADPH oxidase 12
glycerol-3-phosphate dehydrogenase 12
MDH 12
CPT 12
glycerol-3-phosphate dehydrogenase 12
MDH 12
enolase 11
pepsin 11
lactic acid dehydrogenase 11
ornithine decarboxylase 11
AMP deaminase 11
lactic acid dehydrogenase 11
alpha-glucosidase 11
more...
Compound
glucose 1836
creatinine 1706
urea 1637
Clin 1052
GSH 1007
GSH 1007
Dec 1006
nitrogen 886
water 800
alanine 683
sodium 650
calcium 637
oxygen 617
phosphate 574
DNA 574
TNF 568
ethanol 535
glutamate 467
potassium 440
CCl4 390
nitric oxide 376
phosphorus 333
iron 269
2-oxoglutarate 242
ammonia 212
APAP 210
cysteine 189
hydrogen 181
zinc 171
acetate 170
glutamine 167
copper 162
lysine 151
ATP 147
arginine 146
MDA 140
methionine 140
selenium 130
cadmium 117
galactose 109
sulfate 108
hyaluronic acid 104
His 102
tyrosine 101
NAD 97
leucine 95
N-acetylcysteine 95
Phe 94
methanol 90
salt 87
Asp 86
ammonium 85
nitrate 83
CO2 81
NADH 80
NAD 79
Pac 75
Lactate 73
ALP 71
serine 66
NADP 66
Glutamate 65
GPT 65
GSSG 63
tryptophan 62
CAT 62
Silymarin 61
CAT 61
CAT 61
aflatoxin B1 60
PEG 60
tryptophan 60
tryptophan 59
tryptophan 59
DPPH 58
alcohol dehydrogenase 57
dUTP 56
aldehyde 55
NADPH 53
NH2 53
NADPH 53
mercury 52
alloxan 51
AAT 51
oxalacetate 50
PLP 49
Curcumin 48
ethyl acetate 48
aspartic acid 47
MTT 47
homocysteine 47
Insulin 47
ornithine 46
ornithine 46
ornithine 46
ornithine 46
ornithine 46
nicotinamide 45
gallic acid 45
threonine 43
CoA 43
8-OHdG 43
aniline 42
glutamic acid 42
Cardiol 42
silver 41
chloroform 41
Hematoxylin 40
ADP 40
H2O2 40
GABA 38
pyridine 38
Malondialdehyde 38
GABA 38
valine 38
manganese 38
proline 38
vitamin D 37
bromide 37
ADP 35
TCA 35
glycerol 35
AMP 35
ADP 35
Cholesterol 35
Vitamin E 34
Adriamycin 34
phenol 34
chromium 32
Melatonin 31
asparagine 30
Quercetin 30
ADR 30
Ile 30
DDP 29
Bilirubin 29
Hemoglobin 29
acetaldehyde 29
Lead 29
Gly 28
aldehyde 28
acetic acid 27
noradrenaline 27
aspartic acid 27
gamma-aminobutyric acid 27
DMSO 27
caffeine 27
HCl 26
isoleucine 26
Oil Red O 26
isoleucine 26
iodine 26
PEG 26
INH 25
adenosylmethionine 25
acetyl-CoA 25
Arsenic 25
CdCl2 24
cobalt 24
nickel 24
more...