Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P17174 (aspartate aminotransferase)
 14,872 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Blood samples were collected from v. jugularis in five-day intervals from parturition to postpartum day 45 in the rearing conditions of a dairy cow production herd, consisting of 10 groups with 10 pluriparous cows each (crossbreds of Bohemian Pied cattle with Holstein-Friesian cattle). In blood serum the following activities were determined photometrically: aspartate aminotransferase--AST (0.36-0.47 mukat.l-1), gamma-glutamyl transferase--GMT (0.50-0.83 mukat.l-1) and lactate dehydrogenase--LD (7.22-9.10 mukat.l-1); their average values were at an almost constant level. Only did AST and GMT values decrease slightly from day 25 after parturition. The glucose average content on the day of parturition (4.07 mmol.l-1) steeply decreased to postpartum day 5 (2.79 mmol.l-1), and later on, it increased irregularly. The average values of total protein (66.7-73.2 g per 1) slightly increased from postpartum day 20. The values of urea (2.33-2.37 mmol.l-1) and bilirubin (3.49-5.15 mmol.l-1) did not show any larger changes in dependence on the time elapsing from parturition. The average content of creatinine (124-162 mmol.l-1) increased irregularly from postpartum day 15 and then it decreased. Cholesterol concentrations were gradually increasing from 2.58 mmol.l-1 on the day of parturition to 4.99 mmol.l-1 on day 45 after parturition. The average contents of calcium (2.20-2.66 mmol.l-1) and phosphorus (1.75-2.27 mmol.l-1) were irregularly increasing until day 20 after parturition. Also the average content of magnesium (0.86-1.15 mmol.l-1) rose from day 25 after parturition.
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PMID:[Biochemical changes in the peripheral blood in cows 45 days after parturition]. 168 73

Over the period of two years, the blood serum of dairy cows from three localities was examined repeatedly for the activities of aspartate aminotransferase (EC 2.6.1.1) (AST), alanine aminotransferase (EC 2.6.1.2) (ALT) and gammaglutamyltransferase (EC 2.3.2.1) (GMT). First examinations were performed two to four weeks before the expected term of delivery, the repeated examinations between the sixth and eighth week after delivery. The results obtained were used to calculate AST/ALT and GMT/ALT indexes in the studied group of animals (n = 12). As found out, the decrease in these indexes or the equality of values from the sixth to the eighth week after delivery, as compared with the period of two to four weeks prior to delivery, were connected with the clinically detectable disturbances of puerperium, i. e. inflammable discharge from the reproductive organs of dairy cows; this was observed even in the cases when the enzymatic activity was within the references standards.
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PMID:[Development of aspartate aminotransferase, alanine and gamma-glutamyltransferase in the blood serum of dairy cows during the last month of pregnancy and the puerperium in relation to liver function]. 613 81