Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P17174 (
aspartate aminotransferase
)
14,872
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The incidence of hepatitis B and C virus and cytomegalovirus infection is high in patients with the
antiphospholipid syndrome
(
APS
). The specific features of virus infection in
APS
patients are determined by the activity of
APS
. During clinically manifest stage, the activities of aminotransferases, lactate dehydrogenase (LDH), and alkaline phosphatase increase, while during remission only
aspartate aminotransferase
and LDH levels remain high, for this latter enzyme high activities of isoenzymes LDH5 and LDH4 being recorded. These data indicate that the pathological process in
APS
involves not only the liver, but the sinusoidal endothelium as well. This seems to account for some other clinical and laboratory manifestations of
APS
, such as increased level of circulating immune complexes, dysfunction of physiological anticoagulants, etc.
...
PMID:[Biochemical characteristics of liver involvement in patients with antiphospholipid syndrome]. 1120 57
