Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P16104 (
H2AX
)
3,930
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
C20orf135
13.0
H2AX
13.0
H2BFM
13.0
QSCN6
13.0
phosphoinositide-3-kinase adaptor protein 1
13.0
HIST3H2BB
13.0
zinc finger protein 12
13.0
X-ray radiation resistance associated 1
13.0
Tripartite motif-containing protein 29
13.0
Histone H2A type 1
13.0
Histone H2B type 1-K
13.0
KIAA0638
13.0
MARP3
13.0
nucleolar localized protein
13.0
GLB1L
12.0
KRCC1
12.0
ZNF506
12.0
eyes absent 2
12.0
Zinc finger protein 668
12.0
CCDC84
12.0
RGPD6
12.0
CCDC99
12.0
MDC1
11.6
mitogen-activated protein kinase kinase kinase 9
11.4
testis-specific histone H2B
11.4
tumor suppressor p53-binding protein 1
11.4
FIGNL1
11.4
EBNA1BP2
11.4
histone H2A.2
11.4
RAD52 motif 1
11.4
galactosidase, beta 1
11.4
C13orf34
11.4
H2A histone family member
11.4
NFBD1
11.4
KIAA0170
11.2
p53 binding protein
11.1
Eyes absent 2
11.0
Mediator of DNA damage checkpoint 1
11.0
Kinase-related protein
11.0
TMEM24
11.0
zinc finger and SCAN domain containing 21
11.0
LL5A
11.0
PP6R3
11.0
sulfotransferase 1C2
11.0
MAP17 protein
11.0
Histone H1.2
11.0
53BP1
10.9
SPSB3
10.7
nuclear receptor binding protein 2
10.7
DNAJC1
10.7
MIZF
10.7
ATP6V1D
10.7
PRTFDC1
10.7
NRBP2
10.7
zinc finger protein 2
10.7
ATLD
10.7
BRCA2 and CDKN1A interacting protein
10.7
PP6R2
10.4
macroH2A2
10.4
PPP4R2
10.4
ARP8
10.4
Hipk1
10.4
histone H2A.1
10.4
RPA32
10.4
CHK2
10.4
RNF8
10.4
CCDC98
10.2
Werner syndrome helicase
10.2
RNF168
10.2
Rev7p
10.2
PLRG1
10.2
PCID2
10.2
recombination repair protein
10.2
TEX15
10.2
Tousled-like kinase 1
10.2
ATR interacting protein
10.2
HIST1H2AL
10.2
PP6R1
10.2
BRIT1
10.1
ataxia telangiectasia mutated
10.1
more...
Disease
RS-SCID
9.2
oral neoplasm
9.0
ATM
8.8
Mammary adenocarcinoma
8.7
MYP3
8.6
MCPH1
8.5
Senile osteoporosis
8.5
WT3
8.3
neck neoplasm
8.1
FHA
8.0
SCAN1
7.9
FANCN
7.9
FANCJ
7.8
La Crosse encephalitis
7.8
Mandibuloacral dysplasia
7.7
DMAT
7.6
recurrent SCLC
7.5
FA2
7.4
Seckel syndrome
7.2
FANCD1
7.2
XP-A
7.1
glue sniffing
7.1
FANCI
7.0
XPE
7.0
Precancerous lesions
7.0
radiation carcinogenesis
7.0
Cerebellar atrophy
6.9
XPF
6.9
roseola
6.8
testicular embryonal carcinoma
6.7
SCA17
6.7
BMH
6.7
PSN
6.7
ABC-DLBCL
6.6
environmental carcinogenesis
6.6
XPD
6.6
NBS
6.5
Mucolipidosis type IV
6.5
HP1
6.4
Taybi
6.4
Dental fluorosis
6.2
XPB
6.2
PBD
6.2
endocrine cancer
6.2
premature aging
6.1
trisomy 15
6.1
WRN
6.0
optic nerve glioma
6.0
CSB
6.0
CSB
5.9
progeria
5.9
relapsed CLL
5.9
metastatic cervical cancer
5.9
CREST
5.8
Fanconi
5.8
Silence
5.8
carcinoma of the tongue
5.6
Fibrosarcoma
5.6
BLM
5.5
Postoperative cognitive dysfunction
5.5
trichothiodystrophy
5.5
Testicular torsion
5.4
LCS
5.4
Cockayne syndrome
5.4
Chemoradiation
5.4
Middle cerebral artery occlusion
5.3
CDT
5.3
ATRX
5.2
Selenium deficiency
5.2
testicular atrophy
5.2
xeroderma pigmentosum
5.2
FRAXA
5.2
XPG
5.1
Shigella boydii
5.1
malignant meningioma
5.1
HNSCC
5.1
Spitz nevus
5.1
vaginal cancer
5.0
PML
4.9
MIN
4.9
more...
Symptom
Halo
4.1
skin damage
4.0
CSR
3.5
collapse
2.6
hyperoxia
2.6
ataxia
2.5
cerebellar ataxia
2.2
bradykinesia
1.8
exhaustion
1.6
starvation
0.7
hypothermia
0.5
overweight
-0.1
respiratory distress
-0.3
splenomegaly
-0.3
thinning
-0.5
diarrhea
-0.5
erythema
-0.7
anorexia
-0.8
acidity
-0.9
seizures
-1.3
discomfort
-1.5
nausea
-1.5
cough
-1.6
discomfort
-1.6
vomiting
-2.0
fatigue
-2.7
pain
-3.4
anesthesia
-3.8
Drug
Irofulven
9.0
Tricyclazole
8.3
Adozelesin
8.2
Trabectedin
7.4
Epalrestat
7.4
Vorinostat
7.3
Crotonaldehyde
7.3
Sodium ascorbate
7.2
Tipifarnib
6.9
Ciglitazone
6.7
Truvada
6.6
Tolfenamic acid
6.6
7-Nitroindazole
6.5
Tirapazamine
6.5
Mizoribine
6.4
Etoposide
6.3
Mutagen
6.3
Neocarzinostatin
6.2
BLM
6.2
Sesamol
6.1
TFT
6.0
Hyperforin
5.9
Cidofovir
5.9
Areca
5.9
Saha
5.9
Clofarabine
5.9
Oxaliplatin
5.7
Myricetin
5.7
PFT
5.6
Panitumumab
5.6
Podophyllum
5.6
2-Methoxyestradiol
5.6
Dexrazoxane
5.6
Artesunate
5.6
Truvada
5.5
Gatifloxacin
5.5
Gemzar
5.4
ROS
5.4
Mitomycin-C
5.3
Tolvaptan
5.2
Entecavir
5.2
Entecavir
5.2
Cytidine
5.1
Ammonium chloride
5.1
Arsenic trioxide
5.0
Propidium
5.0
Dihydro
5.0
Levovist
4.9
Silica gel
4.8
Bortezomib
4.8
Taxotere
4.7
Erlotinib
4.4
CPT-11
4.4
Rosiglitazone
4.3
Irinotecan
4.3
Aminoguanidine
4.3
Emodin
4.1
Cetuximab
4.1
NVP
4.1
caffeine
4.0
balanced salt solution
4.0
Troglitazone
3.9
Emodin
3.8
Dasatinib
3.7
TTC
3.7
VCR
3.7
Kainic acid
3.6
ZnCl2
3.6
ZnCl2
3.6
ETS
3.6
Lovastatin
3.6
MRC
3.6
ADR
3.6
-deoxyadenosine
3.5
Everolimus
3.5
Sorafenib
3.4
Herceptin
3.4
Adriamycin
3.4
GEO
3.4
Zoledronic acid
3.3
more...
Enzyme
CYP39A1
8.8
PARP
7.2
RNase D
6.9
10-formyltetrahydrofolate dehydrogenase
6.9
CSAD
6.7
topoisomerase
6.4
topoisomerase
6.4
caspase-2
6.4
caspase-2
6.3
CYP7B1
6.0
nicotinamide mononucleotide adenylyltransferase
6.0
endodeoxyribonuclease
5.9
deoxyguanosine kinase
5.8
caspase-7
5.8
arachidonate 5-lipoxygenase
5.8
caspase-7
5.7
histone acetyltransferase
5.6
caspase-3
5.6
caspase-4
5.5
carboxypeptidase G2
5.5
valyl-tRNA synthetase
5.4
caspase-4
5.3
poly(ADP-ribose) glycohydrolase
5.3
endonuclease VII
5.3
DNA ligase
5.3
DNA ligase
5.3
phosphatidylethanolamine N-methyltransferase
5.2
glutathione synthetase
5.2
methylthioadenosine phosphorylase
5.1
STK11
5.1
guanase
5.1
caspase-8
5.1
GAR
5.0
cytosine deaminase
5.0
CEP
5.0
O-GlcNAc transferase
5.0
dihydroorotate dehydrogenase
5.0
protein phosphatase 2A
5.0
dihydroorotate dehydrogenase
5.0
polo-like kinase 1
5.0
cdc2
5.0
ubiquitin-protein ligase
4.9
caspase-9
4.9
pyruvate oxidase
4.9
pyruvate oxidase
4.9
isopeptidase
4.8
ribonucleotide reductase
4.8
PHD
4.8
ALDH
4.8
ribonucleotide reductase
4.8
Fpg protein
4.6
Lys4
4.5
deoxycytidine kinase
4.5
CEP
4.5
DNA methyltransferase
4.4
DCF
4.4
biotinidase
4.4
3'-exonuclease
4.3
HCS
4.3
hypoxanthine-guanine phosphoribosyltransferase
4.3
endonuclease
4.3
histone demethylase
4.1
caspase-6
4.1
phosphoinositide 3-kinase
4.1
cytidine deaminase
4.0
thioredoxin reductase
4.0
cathepsin S
4.0
caspase-6
4.0
asparagine synthetase
4.0
angiotensin-converting enzyme 2
4.0
NQO1
4.0
farnesyltransferase
4.0
HK2
3.9
micrococcal nuclease
3.8
prenyltransferase
3.8
calcineurin
3.8
CDH
3.8
1-hydroxylase
3.8
serine hydroxymethyltransferase
3.8
MTD
3.8
more...
Compound
2-(4-chlorophenyl)benzo-1,4-quinone
12.4
Avenanthramide A
12.0
Eurycomalactone
11.4
Ara-HA
11.0
2'-Hydroxychalcone
11.0
Tebufenpyrad
9.8
Resmethrin
9.5
Quinalizarin
9.5
Microcephalin
9.5
Hedamycin
9.4
Aeroplysinin-1
9.2
Myosmine
9.1
Ovatodiolide
9.1
2,4-DMA
9.0
Butylidenephthalide
8.5
Angelicin
8.5
Saikosaponin A
8.5
Phosphoramide mustard
8.4
Myristicin
8.3
Rafoxanide
8.3
Solanine
8.3
MINA
8.2
Lanatoside C
8.2
Solanine
8.1
1H-benzo[de]isoquinoline-1,3(2H)-dione
8.1
Chloranil
8.0
Plastoquinone
7.9
MTIC
7.9
Fostriecin
7.8
Amentoflavone
7.6
4-methoxybenzaldehyde
7.6
4-methoxybenzaldehyde
7.6
Nitidine
7.6
4-methoxybenzaldehyde
7.5
4-methoxybenzaldehyde
7.5
4-methoxybenzaldehyde
7.5
4-methoxybenzaldehyde
7.5
beta-Lapachone
7.5
7H-dibenzo[c,g]carbazole
7.4
4-methoxybenzaldehyde
7.4
Diepoxybutane
7.4
1,2,4-benzotriazine
7.4
G 1
7.4
hydroxymethylbilane
7.3
4-methoxybenzaldehyde
7.3
Methyleugenol
7.3
4-methoxybenzaldehyde
7.3
Histone
7.2
Phenanthrenequinone
7.2
Anacardic acid
7.2
Juglone
7.1
Potassium bromate
7.0
Carnosol
7.0
10-Hydroxycamptothecin
7.0
Dihydromyricetin
6.9
8-hydroxyguanosine
6.9
HN2
6.9
XPA
6.9
1,2-dichloropropane
6.9
XPA
6.9
Nedaplatin
6.8
Camptothecin
6.8
Camptothecin
6.8
Camptothecin
6.8
Bufalin
6.7
hydrazinecarbothioamide
6.6
2-methylquinoline
6.6
Methacrylic acid
6.6
Azoxymethane
6.6
GRG
6.5
Propylparaben
6.5
Cepharanthine
6.5
Trifluorothymidine
6.5
2-methylquinoline
6.4
methyl methanesulfonate
6.4
DMAE
6.4
8-OHdG
6.4
Hyperoside
6.3
IBT
6.3
Neocarzinostatin
6.2
more...