Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P16104 (H2AX)
3,930 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein H2AX 3930 histone 1173 p53 711 ATM 606 Mol 448 53BP1 322 ATR 284 caspase-3 275 Chk1 262 DNA-dependent protein kinase 262 Sep 245 p21 233 BRCA1 209 PARP 209 Chk2 179 ataxia telangiectasia mutated 143 Rad51 134 RAD51 130 A-T 126 MDC1 123 ROS 99 Bcl-2 93 histone H2A 92 NBS1 88 histone H3 85 H2A 77 CHK2 74 Ku70 72 p38 68 PARP-1 68 CHK1 66 histone deacetylase 63 ubiquitin 62 poly(ADP-ribose) polymerase 60 phosphatase 59 proliferating cell nuclear antigen 58 ATP 58 telomeric 58 Rad50 57 MRE11 57 more...

Disease cancer 1156 ATM 706 tumor 634 breast cancer 201 carcinogenesis 130 tumorigenesis 108 carcinoma 104 tumor growth 102 lung cancer 92 leukemia 88 MCF 71 prostate cancer 69 glioblastoma 64 adenocarcinoma 63 colorectal cancer 62 glioma 59 colon cancer 58 hepatocellular carcinoma 58 melanoma 48 non-small cell lung cancer 48 ovarian cancer 47 tumor progression 44 lymphoma 40 cervical cancer 37 acute myeloid leukemia 34 squamous cell carcinoma 33 pancreatic cancer 32 anemia 30 osteosarcoma 30 Fanconi 28 GSH 23 neuroblastoma 23 glioblastoma multiforme 22 SCID 22 ischemia 22 B-cell lymphoma 21 NBS 21 lung carcinoma 21 retinoblastoma 21 premature aging 19 more...

Symptom collapse 22 ataxia 11 starvation 5 diarrhea 5 exhaustion 5 seizures 4 hyperoxia 4 overweight 3 hypothermia 3 pain 3 skin damage 3 respiratory distress 2 cerebellar ataxia 2 cough 1 discomfort 1 nausea 1 anesthesia 1 Halo 1 anorexia 1 bradykinesia 1 thinning 1 discomfort 1 acidity 1 splenomegaly 1 erythema 1 vomiting 1 CSR 1 fatigue 1

Drug ROS 99 lysine 69 Mutagen 57 caffeine 43 BLM 12 ascorbate 12 Etoposide 11 Dermatol 9 DNase I 8 Vorinostat 7 ZnO 6 Adriamycin 6 Monit 6 Oxaliplatin 6 Glutathione 5 Arsenic trioxide 5 MAP 5 MRC 5 CPT-11 5 Indomethacin 5 Bortezomib 5 ETS 4 NADH 3 TiO2 3 -deoxyadenosine 3 HCH 3 CSF 3 PFT 3 vitamin E 3 Trabectedin 3 CTX 3 Gel 3 TTC 3 ADR 3 Herceptin 3 balanced salt solution 3 Erlotinib 2 Docetaxel 2 Areca 2 TFT 2 more...

Enzyme PARP 255 caspase-3 208 mitogen-activated protein kinase 117 protein kinase 112 topoisomerase 103 topoisomerase 96 ERK 84 superoxide dismutase 53 catalase 45 endonuclease 44 proteasome 37 cdc2 32 calcineurin 30 caspase-8 29 caspase-9 28 DNA polymerase 25 ATPase 22 luciferase 21 focal adhesion kinase 20 MEK 18 RNA polymerase 18 beta-galactosidase 16 histone acetyltransferase 16 DNA ligase 13 DNA methyltransferase 13 phosphatidylinositol 3-kinase 13 DNA ligase 13 NQO1 12 protein phosphatase 2A 12 lactate dehydrogenase 12 AMP-activated protein kinase 12 phosphoinositide 3-kinase 12 glutathione peroxidase 11 ribonucleotide reductase 10 ribonucleotide reductase 10 caspase-2 8 protein kinase C 8 AMPK 8 caspase-2 8 AMPK 8 more...

Compound DNA 3417 oxygen 355 Dec 265 serine 227 Histone 91 lysine 77 hydrogen 65 MTT 62 cysteine 62 ATP 58 MDA 53 threonine 52 ADP-ribose 51 TNF 45 water 45 ADP 45 N-acetylcysteine 44 caffeine 43 ADP 42 ADP 42 iodine 41 H2O2 40 tyrosine 33 8-OHdG 33 sodium 33 iron 32 pyrene 32 Clin 29 GSH 28 GSH 28 Adriamycin 27 methyl methanesulfonate 25 ADR 24 calcium 23 diacetate 23 nitric oxide 22 NAD 22 dUTP 22 nitrogen 21 NAD 20 more...

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