Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P16104 (H2AX)
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Human Gene/Protein
HIST3H2BB 13.0
X-ray radiation resistance associated 1 13.0
KIAA0638 13.0
C20orf135 13.0
Histone H2B type 1-K 13.0
H2BFM 13.0
zinc finger protein 12 13.0
H2AX 13.0
phosphoinositide-3-kinase adaptor protein 1 13.0
QSCN6 13.0
Histone H2A type 1 13.0
nucleolar localized protein 13.0
MARP3 13.0
Tripartite motif-containing protein 29 13.0
RGPD6 12.0
GLB1L 12.0
CCDC99 12.0
CCDC84 12.0
Zinc finger protein 668 12.0
ZNF506 12.0
KRCC1 12.0
eyes absent 2 12.0
MDC1 11.6
mitogen-activated protein kinase kinase kinase 9 11.4
tumor suppressor p53-binding protein 1 11.4
testis-specific histone H2B 11.4
FIGNL1 11.4
galactosidase, beta 1 11.4
EBNA1BP2 11.4
RAD52 motif 1 11.4
C13orf34 11.4
histone H2A.2 11.4
H2A histone family member 11.4
NFBD1 11.4
KIAA0170 11.2
p53 binding protein 11.1
Histone H1.2 11.0
MAP17 protein 11.0
LL5A 11.0
TMEM24 11.0
sulfotransferase 1C2 11.0
Mediator of DNA damage checkpoint 1 11.0
Eyes absent 2 11.0
PP6R3 11.0
Kinase-related protein 11.0
zinc finger and SCAN domain containing 21 11.0
53BP1 10.9
zinc finger protein 2 10.7
DNAJC1 10.7
ATLD 10.7
BRCA2 and CDKN1A interacting protein 10.7
MIZF 10.7
NRBP2 10.7
ATP6V1D 10.7
PRTFDC1 10.7
SPSB3 10.7
nuclear receptor binding protein 2 10.7
RPA32 10.4
Hipk1 10.4
macroH2A2 10.4
ARP8 10.4
PPP4R2 10.4
histone H2A.1 10.4
PP6R2 10.4
CHK2 10.4
RNF8 10.4
CCDC98 10.2
Werner syndrome helicase 10.2
RNF168 10.2
Rev7p 10.2
TEX15 10.2
recombination repair protein 10.2
PCID2 10.2
PP6R1 10.2
ATR interacting protein 10.2
Tousled-like kinase 1 10.2
PLRG1 10.2
HIST1H2AL 10.2
BRIT1 10.1
ataxia telangiectasia mutated 10.1
DNA topoisomerase 2 10.1
meiotic recombination 11 10.0
Chk2 10.0
PYROXD1 10.0
TMEM79 10.0
DHP1 10.0
LL5beta 10.0
POLR2F 10.0
BTBD12 10.0
Relaxin 3 10.0
TREH 10.0
RNF26 10.0
STRN3 10.0
HIST1H2BK 10.0
H2A.X 9.9
NBS1 9.9
NEK4 9.9
FOXN5 9.8
Arp5 9.8
MEI1 9.8
M-LPH 9.8
ALG-4 9.8
HIST2H2BE 9.8
TSKS 9.8
Histone H2A 9.8
RPA2 9.8
ATM 9.7
HUS1 9.7
BRCC45 9.7
macroH2A1.2 9.7
kinase-related protein 9.7
cytochrome c, somatic 9.7
RAD54B 9.7
TNFAIP8L1 9.7
PDZK2 9.7
OTUB2 9.7
TOPBP1 9.6
CHK1 9.6
WIP1 9.6
SYCP1 9.6
p202 9.6
NADPH oxidase 1 9.6
FANCA protein 9.6
SMC1 9.6
MRE11 9.5
DNA-dependent protein kinase 9.5
TPD52L1 9.5
Monad 9.5
RPA4 9.5
DDX18 9.5
Microcephalin 9.5
TRAPPC4 9.5
ribonuclease H2 9.5
ubiquitin-specific protease 3 9.5
Chk1 9.5
CTIP 9.5
NHEJ1 9.5
PTIP 9.5
H2AZ 9.4
MADA 9.4
BRCA1-associated RING domain 1 9.4
X-ray repair cross-complementing protein 4 9.4
PNAS-4 9.4
PBL1 9.4
YAF2 9.4
ROGDI 9.4
ALKBH8 9.4
TSSK6 9.4
GNAI2 9.4
cell cycle checkpoint protein 9.4
USP3 9.3
H2A histone 9.3
histone H1.2 9.3
histone H2A 9.3
Wip1 9.3
P53-binding protein 9.3
Leucine-rich repeats and immunoglobulin-like domains protein 1 9.3
NUP133 9.3
ARCN1 9.3
STBP 9.3
DDA1 9.3
DEK gene 9.3
C1QTNF5 9.3
Rad51 9.2
SYCP3 9.2
SNM1A 9.2
histone family member 9.2
hPMC2 9.2
prostaglandin reductase 2 9.2
topoisomerase II beta 9.2
SYCE2 9.2
CENPB 9.2
budding uninhibited by benzimidazoles 1 9.2
Rad50 9.1
H2A.2 9.1
PP4C 9.1
Translin-associated factor X 9.1
XRCC4 protein 9.1
down-regulated in human cancers 9.1
ITM2A 9.1
DPYSL3 9.1
ZMYM3 9.1
protein phosphatase 6 9.1
hRad50 9.1
LIM domain containing 2 9.1
nibrin 9.1
RAD51 9.1
FANCB 9.0
Ku80 9.0
RAD50 9.0
RUVBL2 9.0
H2A.1 9.0
Ku70 9.0
CYP39A1 9.0
NSMCE2 9.0
SUV39H2 9.0
collagen, type I, alpha 1 9.0
KEPI 9.0
Bloom's syndrome protein 9.0
SESN1 9.0
MCM7 protein 8.9
p53-binding protein 8.9
CtIP 8.9
Ino80 8.9
Speckle-type POZ protein 8.9
MNSOD 8.9
TERF1 8.9
CGL-2 8.9
RAP80 8.9
COX7A 8.9
PRKAG1 8.9
MGR 8.9
ATMIN 8.9
UBC13 8.8
RNF20 8.8
TIP49 8.8
L3MBTL2 8.8
ITSN2 8.8
SUPT16H 8.8
VPS11 8.8
RDM1 8.8
TP53BP1 8.8
POLD4 8.8
NPRL2 8.8
MKNK2 8.7
ATR-interacting protein 8.7
RDH11 8.7
SDS22 8.7
EYA3 8.7
PDC2 8.7
FDXR 8.7
Nuclear receptor coactivator 6 8.7
INO80 8.7
RAD23B 8.7
STE20-like kinase 8.7
histone protein 8.7
KU70 8.7
Ku86 8.7
calcium binding and coiled-coil domain 2 8.7
TP53I3 8.7
nap1 8.7
p53R2 8.7
PPM1D 8.6
TIP60 8.6
Rvb2 8.6
HMT1 8.6
NDH II 8.6
SCML2 8.6
Guanine deaminase 8.6
H2A.Bbd 8.6
Poly(ADP-ribose) glycohydrolase 8.6
telomeric repeat binding factor 2 8.6
APC3 8.6
TRAIP 8.6
POLD3 8.6
RNF40 8.6
RBBP8 8.6
nuclear mitotic apparatus protein 1 8.5
PHAX 8.5
POLD2 8.5
EXOSC10 8.5
sodium-dependent organic anion transporter 8.5
ValRS 8.5
CIRBP 8.5
CDC25C 8.5
XRCC7 8.5
KAP1 8.5
SNF2H 8.5
PHD zinc finger 8.5
CUX2 8.5
REV3L 8.5
PUB 8.5
ATR 8.5
XRCC4 8.4
XRCC6 8.4
XLF 8.4
BRCC36 8.4
ATM protein 8.4
cell division cycle 25A 8.4
CEP152 8.4
MYP 8.4
EKI1 8.4
AMIGO2 8.4
SLC22A16 8.4
MCPH1 8.4
Williams syndrome transcription factor 8.4
BCL9L 8.3
XRCC5 8.3
Atg21 8.3
PPP6C 8.3
CBX5 8.3
HYOU1 8.3
PIK3AP1 8.3
CSAD 8.3
ETAA1 8.3
TopBP1 8.3
And-1 8.3
GLTSCR2 8.3
PIAS4 8.3
mH2A1 8.3
TRF2 8.3
MORC 8.3
SMC3 8.3
RPAP3 8.2
Btf 8.2
RING2 8.2
NOMO 8.2
TNRC9 8.2
GANP 8.2
synaptonemal complex protein 1 8.2
A-T 8.2
Mina53 8.2
TRIM29 8.2
CHEK1 8.2
MRE11A 8.2
DDB2 8.2
Nibrin 8.2
RPS25 8.2
ubiquinol-cytochrome c reductase complex 8.2
CARP-1 8.2
more...
Disease
RS-SCID 9.2
oral neoplasm 9.0
ATM 8.8
Mammary adenocarcinoma 8.7
MYP3 8.6
MCPH1 8.5
Senile osteoporosis 8.5
WT3 8.3
neck neoplasm 8.1
FHA 8.0
SCAN1 7.9
FANCN 7.9
FANCJ 7.8
La Crosse encephalitis 7.8
Mandibuloacral dysplasia 7.7
DMAT 7.6
recurrent SCLC 7.5
FA2 7.4
Seckel syndrome 7.2
FANCD1 7.2
XP-A 7.1
glue sniffing 7.1
FANCI 7.0
Precancerous lesions 7.0
XPE 7.0
radiation carcinogenesis 7.0
Cerebellar atrophy 6.9
XPF 6.9
roseola 6.8
testicular embryonal carcinoma 6.7
BMH 6.7
SCA17 6.7
PSN 6.7
ABC-DLBCL 6.6
environmental carcinogenesis 6.6
XPD 6.6
NBS 6.5
Mucolipidosis type IV 6.5
HP1 6.4
Taybi 6.4
Dental fluorosis 6.2
XPB 6.2
PBD 6.2
endocrine cancer 6.2
premature aging 6.1
trisomy 15 6.1
WRN 6.0
optic nerve glioma 6.0
CSB 6.0
CSB 5.9
progeria 5.9
metastatic cervical cancer 5.9
relapsed CLL 5.9
CREST 5.8
Fanconi 5.8
Silence 5.8
carcinoma of the tongue 5.6
Fibrosarcoma 5.6
BLM 5.5
Postoperative cognitive dysfunction 5.5
trichothiodystrophy 5.5
Testicular torsion 5.4
LCS 5.4
Cockayne syndrome 5.4
Chemoradiation 5.4
Middle cerebral artery occlusion 5.3
CDT 5.3
ATRX 5.2
Selenium deficiency 5.2
testicular atrophy 5.2
xeroderma pigmentosum 5.2
FRAXA 5.2
XPG 5.1
Shigella boydii 5.1
malignant meningioma 5.1
HNSCC 5.1
Spitz nevus 5.1
vaginal cancer 5.0
PML 4.9
MIN 4.9
MIN 4.9
Ovary 4.9
RSS 4.9
glioblastoma 4.8
BFR 4.8
tobacco abuse 4.8
BPP 4.8
CEP 4.8
HCC 4.8
neoplastic transformation 4.7
Desmoplastic small round cell tumor 4.7
hormone refractory prostate cancer 4.7
Rhabdomyosarcoma 4.7
Meningioma 4.6
Meningioma 4.6
CYLD 4.6
recurrent prostate cancer 4.6
Esophageal squamous cell carcinoma 4.6
Abdomen 4.6
refractory CLL 4.5
melanoma in situ 4.5
Severe sepsis 4.5
DSS 4.5
spindle cell sarcoma 4.5
HMR 4.5
Glioblastoma 4.5
Fallopian tube 4.5
HOS 4.4
SMC 4.4
MCF 4.3
CIN 4.3
dysplastic nevi 4.3
NLS 4.3
renal clear cell carcinoma 4.3
glioblastoma multiforme 4.3
FDH 4.3
T-cell acute lymphoblastic leukemia 4.3
DSS 4.2
acute monocytic leukemia 4.2
MRD 4.2
AGS 4.2
MTS 4.2
Ovary 4.1
non-small cell lung cancer 4.1
benign nevi 4.1
chancroid 4.1
EMT 4.1
immunotoxicity 4.1
LMS 4.0
LMS 4.0
colon cancer 4.0
carcinogenesis 4.0
SCID 4.0
Testes 4.0
pediatric brain tumor 4.0
HML 4.0
HGF 4.0
Leiomyosarcoma 4.0
western equine encephalomyelitis 4.0
TAS 4.0
glioma 4.0
retinoblastoma 3.9
tumorigenesis 3.9
premalignant condition 3.9
Osteosarcoma 3.9
Osteosarcoma 3.9
osteosarcoma 3.9
malignant mesothelioma 3.9
seborrheic keratosis 3.9
oligospermia 3.8
myeloid leukemia 3.8
tumor growth 3.8
oropharyngeal squamous cell carcinoma 3.8
esophageal cancer 3.8
Barrett's esophagus 3.8
ovarian cancer 3.8
cervical cancer 3.8
Cowden syndrome 3.8
Common variable immunodeficiency 3.7
mantle cell lymphoma 3.7
intestinal cancer 3.7
NMS 3.7
esophageal cancer 3.7
adult T-cell leukemia/lymphoma 3.7
chronic lymphocytic leukemia 3.7
pancreatic cancer 3.7
Thyroid cancer 3.7
genetic disorder 3.6
acute promyelocytic leukemia 3.6
Diffuse large B-cell lymphoma 3.6
OPA1 3.6
DDP 3.6
hand-foot syndrome 3.6
kernicterus 3.6
chemical carcinogenesis 3.6
oral cancer 3.5
stromal tumors 3.5
CEM 3.5
dyskeratosis congenita 3.5
MCL 3.5
fallopian tube 3.5
chronic lymphocytic leukemia 3.4
monocytic leukemia 3.4
Blocking 3.4
residual cancer 3.4
monoclonal gammopathy of undetermined significance 3.4
gastrointestinal cancer 3.4
B-cell lymphomas 3.4
Spinocerebellar ataxia 3.4
DLBCL 3.4
lung cancer 3.4
Recruitment 3.4
PMS 3.4
B-cell lymphoma 3.4
breast cancer 3.3
AIN 3.3
fibrosarcoma 3.3
Fanconi syndrome 3.3
Pineal 3.3
folate deficiency 3.3
blast crisis 3.3
adrenocortical carcinoma 3.2
Melanoma 3.2
colorectal cancer 3.2
prostate cancer 3.2
NS2 3.2
astrocytoma 3.2
Cholangiocarcinoma 3.2
MAR 3.2
Nasopharyngeal carcinoma 3.2
FBS 3.2
liver cancer 3.2
skin cancer 3.2
male infertility 3.2
B-cell chronic lymphocytic leukemia 3.2
hyperosmolality 3.2
NMS 3.2
MEC 3.2
hematologic malignancies 3.1
tumor progression 3.1
rectal prolapse 3.1
Sarcoma 3.1
Sarcoma 3.1
cancer 3.1
LMS 3.1
Ewing's sarcoma 3.1
parvovirus 3.1
Cholangiocarcinoma 3.0
myeloblastosis 3.0
Peutz-Jeghers syndrome 3.0
head and neck cancer 3.0
Li-Fraumeni syndrome 3.0
leukemogenesis 3.0
bladder cancer 3.0
Testis 3.0
Testis 3.0
NPC 3.0
papilloma 3.0
acute myeloid leukemia 3.0
bone cancer 3.0
Dermal 2.9
brain cancer 2.9
leukemia 2.9
GCE 2.9
pseudomembranous colitis 2.9
Williams syndrome 2.9
small cell lung cancer 2.9
tumor 2.9
solid tumor 2.9
adenocarcinoma 2.9
carcinoma of the pancreas 2.9
testicular cancer 2.9
proctitis 2.9
Neuroblastoma 2.9
Neuroblastoma 2.9
Wiskott-Aldrich syndrome 2.9
Condensation 2.9
lung carcinoma 2.8
Leukemia 2.8
osteoarthritis of the knee 2.8
fascioliasis 2.8
tumor initiation 2.8
medulloblastoma 2.8
tumor vasculature 2.8
acoustic neuroma 2.8
carcinoma of the esophagus 2.8
neuroblastoma 2.7
anaplastic astrocytoma 2.7
hepatocellular carcinoma 2.7
tubular necrosis 2.7
lichen sclerosus 2.7
MRT 2.7
Krabbe disease 2.7
Behcet's disease 2.7
renal ischemia 2.7
Hepatocellular carcinoma 2.7
megaloblastic anemia 2.7
ARC 2.7
epithelial ovarian cancer 2.7
lymphoblastic leukemia 2.7
FTC 2.7
metastatic renal cell carcinoma 2.6
human papilloma virus 2.6
human papilloma virus 2.6
BDE 2.6
telangiectasia 2.6
squamous cell carcinoma 2.6
leukoplakia 2.6
hairy cell leukemia 2.6
NOD 2.6
Merkel cell carcinoma 2.6
T-cell lymphomas 2.6
chronic myelomonocytic leukemia 2.6
enzyme deficiency 2.6
Adenocarcinoma 2.6
MMA 2.5
mesothelioma 2.5
CES 2.5
liver cancer 2.5
sarcoma 2.5
melanoma 2.5
carcinoma 2.5
neoplastic process 2.5
Clostridium difficile infection 2.5
TTP 2.5
myelodysplastic syndrome 2.4
MICA 2.4
lysosomal storage disease 2.4
cervical intraepithelial neoplasia 2.4
Huntington's disease 2.4
AAA 2.4
ABL 2.4
reflux esophagitis 2.4
gastrointestinal stromal tumor 2.4
rhabdomyosarcoma 2.4
gallbladder cancer 2.4
lymphangioleiomyomatosis 2.4
uveal melanoma 2.4
premature ovarian failure 2.4
chronic myeloid leukemia 2.4
more...
Symptom
Halo 4.1
skin damage 4.0
CSR 3.5
collapse 2.6
hyperoxia 2.6
ataxia 2.5
cerebellar ataxia 2.2
bradykinesia 1.8
exhaustion 1.6
starvation 0.7
hypothermia 0.5
overweight -0.1
respiratory distress -0.3
splenomegaly -0.3
thinning -0.5
diarrhea -0.5
erythema -0.7
anorexia -0.8
acidity -0.9
seizures -1.3
discomfort -1.5
nausea -1.5
cough -1.6
discomfort -1.6
vomiting -2.0
fatigue -2.7
pain -3.4
anesthesia -3.8
Drug
Irofulven 9.0
Tricyclazole 8.3
Adozelesin 8.2
Trabectedin 7.4
Epalrestat 7.4
Vorinostat 7.3
Crotonaldehyde 7.3
Sodium ascorbate 7.2
Tipifarnib 6.9
Ciglitazone 6.7
Truvada 6.6
Tolfenamic acid 6.6
7-Nitroindazole 6.5
Tirapazamine 6.5
Mizoribine 6.4
Etoposide 6.3
Mutagen 6.3
Neocarzinostatin 6.2
BLM 6.2
Sesamol 6.1
TFT 6.0
Hyperforin 5.9
Cidofovir 5.9
Areca 5.9
Saha 5.9
Clofarabine 5.9
Oxaliplatin 5.7
Myricetin 5.7
Panitumumab 5.6
PFT 5.6
Podophyllum 5.6
2-Methoxyestradiol 5.6
Dexrazoxane 5.6
Artesunate 5.6
Truvada 5.5
Gatifloxacin 5.5
Gemzar 5.4
ROS 5.4
Mitomycin-C 5.3
Tolvaptan 5.2
Entecavir 5.2
Entecavir 5.2
Cytidine 5.1
Ammonium chloride 5.1
Arsenic trioxide 5.0
Propidium 5.0
Dihydro 5.0
Levovist 4.9
Silica gel 4.8
Bortezomib 4.8
Taxotere 4.7
Erlotinib 4.4
CPT-11 4.4
Rosiglitazone 4.3
Irinotecan 4.3
Aminoguanidine 4.3
Emodin 4.1
Cetuximab 4.1
NVP 4.1
caffeine 4.0
balanced salt solution 4.0
Troglitazone 3.9
Emodin 3.8
Dasatinib 3.7
TTC 3.7
VCR 3.7
Kainic acid 3.6
ZnCl2 3.6
ZnCl2 3.6
ETS 3.6
Lovastatin 3.6
MRC 3.6
ADR 3.6
-deoxyadenosine 3.5
Everolimus 3.5
Sorafenib 3.4
Herceptin 3.4
Adriamycin 3.4
GEO 3.4
Zoledronic acid 3.3
Pravastatin 3.3
lysine 3.3
Docetaxel 3.2
DBS 3.2
Gastro 3.2
Reserpine 3.0
Check 3.0
PFA 3.0
DNase I 3.0
CTC 2.9
AraC 2.9
Glutathione 2.9
G418 2.9
DMAP 2.8
HCH 2.8
Imatinib 2.7
Vitamin B 2.7
Indomethacin 2.7
CTC 2.7
Nitric Oxide 2.6
AZT 2.6
Gleevec 2.5
MOF 2.4
AZT 2.4
VCR 2.4
TAC 2.3
Vitamin E 2.3
Parkin 2.1
Parkin 2.1
ascorbate 2.1
ACT 1.9
Paraffin 1.9
Estrogens 1.8
ZnO 1.8
Fragment 1.8
Silica 1.8
TAT 1.8
Albumin 1.8
Fraction 1.7
Forskolin 1.6
G-CSF 1.6
Fluorescein 1.6
Alanine 1.5
ALA 1.5
Rituximab 1.5
Heme 1.4
MAP 1.4
Taxol 1.3
CTX 1.3
Fluorescein 1.1
TiO2 1.1
p75 1.1
PCB 0.9
ENT 0.9
Gel 0.7
Angiotensin II 0.7
FAD 0.6
CAM 0.5
Monit 0.5
vitamin E 0.5
Bifidobacterium 0.5
PTH 0.2
NH3 0.2
EPA 0.2
NADH 0.1
ROC 0.1
EE2 0.1
THF -0.0
ampicillin -0.1
Ethanol -0.3
CSF -0.3
Leaf -0.4
lactose -1.0
Nephron -1.1
Dermatol -1.8
IL-2 -1.8
Cardiovasc -4.6
Enzyme
CYP39A1 8.8
PARP 7.2
RNase D 6.9
10-formyltetrahydrofolate dehydrogenase 6.9
CSAD 6.7
topoisomerase 6.4
topoisomerase 6.4
caspase-2 6.4
caspase-2 6.3
CYP7B1 6.0
nicotinamide mononucleotide adenylyltransferase 6.0
endodeoxyribonuclease 5.9
deoxyguanosine kinase 5.8
caspase-7 5.8
arachidonate 5-lipoxygenase 5.8
caspase-7 5.7
histone acetyltransferase 5.6
caspase-3 5.6
caspase-4 5.5
carboxypeptidase G2 5.5
valyl-tRNA synthetase 5.4
caspase-4 5.3
poly(ADP-ribose) glycohydrolase 5.3
endonuclease VII 5.3
DNA ligase 5.3
DNA ligase 5.3
glutathione synthetase 5.2
phosphatidylethanolamine N-methyltransferase 5.2
methylthioadenosine phosphorylase 5.1
STK11 5.1
guanase 5.1
caspase-8 5.1
GAR 5.0
cytosine deaminase 5.0
CEP 5.0
O-GlcNAc transferase 5.0
dihydroorotate dehydrogenase 5.0
protein phosphatase 2A 5.0
dihydroorotate dehydrogenase 5.0
polo-like kinase 1 5.0
cdc2 5.0
ubiquitin-protein ligase 4.9
caspase-9 4.9
pyruvate oxidase 4.9
pyruvate oxidase 4.9
isopeptidase 4.8
ribonucleotide reductase 4.8
PHD 4.8
ALDH 4.8
ribonucleotide reductase 4.8
Fpg protein 4.6
Lys4 4.5
deoxycytidine kinase 4.5
CEP 4.5
DNA methyltransferase 4.4
DCF 4.4
biotinidase 4.4
3'-exonuclease 4.3
HCS 4.3
hypoxanthine-guanine phosphoribosyltransferase 4.3
endonuclease 4.3
histone demethylase 4.1
caspase-6 4.1
phosphoinositide 3-kinase 4.1
cytidine deaminase 4.0
thioredoxin reductase 4.0
cathepsin S 4.0
caspase-6 4.0
asparagine synthetase 4.0
angiotensin-converting enzyme 2 4.0
NQO1 4.0
farnesyltransferase 4.0
HK2 3.9
micrococcal nuclease 3.8
prenyltransferase 3.8
calcineurin 3.8
CDH 3.8
1-hydroxylase 3.8
serine hydroxymethyltransferase 3.8
prenyltransferase 3.8
MTD 3.8
thymidylate synthase 3.8
HDR 3.7
xanthine dehydrogenase 3.7
prenyltransferase 3.7
factor C 3.7
porphobilinogen deaminase 3.7
polynucleotide kinase 3.6
DNA polymerase 3.6
adenine phosphoribosyltransferase 3.5
gamma-glutamylcysteine synthetase 3.5
protein kinase 3.5
deoxyribonuclease 3.5
MAT 3.4
farnesyltransferase 3.4
proteasome 3.4
AMPK 3.4
mitogen-activated protein kinase 3.3
methionine synthase 3.3
PST 3.3
PAT 3.3
phosphatidylinositol 3-kinase 3.3
MAT 3.2
KAT 3.2
peroxiredoxin 3.2
Pla 3.2
IMP dehydrogenase 3.2
methionine synthase 3.2
beta-galactosidase 3.1
MPP 3.1
TdT 3.1
PRE 3.1
cystathionine beta-synthase 3.1
GSK 3.1
MEK 3.0
nucleotidase 3.0
thymidine phosphorylase 3.0
cathepsin B 3.0
ECH 2.9
AMP-activated protein kinase 2.9
matrix metalloproteinase 9 2.9
flavin-containing monooxygenase 2.9
superoxide dismutase 2.9
PDK1 2.9
3-hydroxy-3-methylglutaryl-CoA reductase 2.9
GRK5 2.8
ERK 2.8
catalase 2.7
DNase 2.7
cathepsin D 2.6
demethylase 2.6
heme oxygenase 2.5
TPP 2.5
glyceraldehyde-3-phosphate dehydrogenase 2.5
glyceraldehyde-3-phosphate dehydrogenase 2.5
glucocerebrosidase 2.5
MAP 2.5
deoxyribonuclease 2.4
triphosphatase 2.4
apyrase 2.4
AMPK 2.4
glyceraldehyde-3-phosphate dehydrogenase 2.4
CPT 2.3
succinate dehydrogenase 2.3
alpha-galactosidase 2.3
CPT 2.2
aconitase 2.2
prostate-specific membrane antigen 2.2
luciferase 2.2
MEKK1 2.1
PAM 2.1
glyceraldehyde-3-phosphate dehydrogenase 2.1
thymidine kinase 2.1
RNA polymerase 2.1
adenylate kinase 2.1
glutathione peroxidase 2.0
CYP3A4 1.9
glyceraldehyde-3-phosphate dehydrogenase 1.9
CAD 1.9
focal adhesion kinase 1.9
MDR 1.9
CAD 1.9
complex I 1.9
ADH 1.9
NADPH oxidase 1.8
CAD 1.8
CPT 1.8
glutathione reductase 1.8
TAT 1.8
histidine kinase 1.8
NOS 1.7
lactate dehydrogenase 1.7
IKK 1.7
CDR 1.7
NADPH oxidase 1.7
SPC 1.6
asparaginase 1.6
APC 1.6
RNase H 1.6
firefly luciferase 1.5
glucokinase 1.5
ATPase 1.4
RNase 1.4
AST 1.4
caspase-1 1.4
transcriptase 1.4
glutathione S-transferase 1.3
granzyme B 1.3
MMP-3 1.2
CD13 1.2
collagenase 1.1
phosphodiesterase 1.1
glucose-6-phosphate dehydrogenase 1.1
proteinase K 1.0
RNase 1.0
xanthine oxidase 1.0
chitinase 0.9
cytochrome oxidase 0.9
P-glycoprotein 0.9
alanine aminotransferase 0.9
hyaluronidase 0.8
monoamine oxidase 0.6
aspartate aminotransferase 0.6
tissue plasminogen activator 0.5
protein kinase C 0.4
hyaluronidase 0.4
ornithine decarboxylase 0.4
ribonuclease 0.3
ribonuclease 0.3
urease 0.2
carbonic anhydrase 0.1
urease 0.1
reverse transcriptase 0.0
gamma-glutamyl transpeptidase -0.2
tyrosinase -0.2
alcohol dehydrogenase -0.2
CD10 -0.3
urokinase-type plasminogen activator -0.4
peroxidase -0.4
ACS -0.7
NO synthase -1.0
alkaline phosphatase -1.0
ACE -1.2
creatine kinase -1.2
adenylate cyclase -1.2
acetylcholinesterase -1.8
renin -2.1
trypsin -2.4
Compound
2-(4-chlorophenyl)benzo-1,4-quinone 12.4
Avenanthramide A 12.0
Eurycomalactone 11.4
Ara-HA 11.0
2'-Hydroxychalcone 11.0
Tebufenpyrad 9.8
Resmethrin 9.5
Quinalizarin 9.5
Microcephalin 9.5
Hedamycin 9.4
Aeroplysinin-1 9.2
Myosmine 9.1
Ovatodiolide 9.1
2,4-DMA 9.0
Angelicin 8.5
Butylidenephthalide 8.5
Saikosaponin A 8.5
Phosphoramide mustard 8.4
Myristicin 8.3
Rafoxanide 8.3
Solanine 8.3
MINA 8.2
Lanatoside C 8.2
1H-benzo[de]isoquinoline-1,3(2H)-dione 8.1
Solanine 8.1
Chloranil 8.0
Plastoquinone 7.9
MTIC 7.9
Fostriecin 7.8
Amentoflavone 7.6
Nitidine 7.6
4-methoxybenzaldehyde 7.6
4-methoxybenzaldehyde 7.6
4-methoxybenzaldehyde 7.5
4-methoxybenzaldehyde 7.5
4-methoxybenzaldehyde 7.5
beta-Lapachone 7.5
4-methoxybenzaldehyde 7.5
7H-dibenzo[c,g]carbazole 7.4
4-methoxybenzaldehyde 7.4
Diepoxybutane 7.4
1,2,4-benzotriazine 7.4
G 1 7.4
hydroxymethylbilane 7.3
4-methoxybenzaldehyde 7.3
Methyleugenol 7.3
4-methoxybenzaldehyde 7.3
Histone 7.2
Phenanthrenequinone 7.2
Anacardic acid 7.2
Juglone 7.1
Potassium bromate 7.0
Carnosol 7.0
10-Hydroxycamptothecin 7.0
Dihydromyricetin 6.9
8-hydroxyguanosine 6.9
HN2 6.9
XPA 6.9
1,2-dichloropropane 6.9
XPA 6.9
Nedaplatin 6.8
Camptothecin 6.8
Camptothecin 6.8
Camptothecin 6.8
Bufalin 6.7
hydrazinecarbothioamide 6.6
2-methylquinoline 6.6
Methacrylic acid 6.6
Azoxymethane 6.6
GRG 6.5
Propylparaben 6.5
Cepharanthine 6.5
Trifluorothymidine 6.5
2-methylquinoline 6.4
methyl methanesulfonate 6.4
DMAE 6.4
8-OHdG 6.4
Hyperoside 6.3
IBT 6.3
Neocarzinostatin 6.2
Calyculin A 6.2
DHM 6.2
Cyclopamine 6.2
PBD 6.2
2-butenal 6.2
TIF 6.2
Bisphenol S 6.1
ADP-ribose 6.1
Sesamol 6.1
Temozolomide 6.1
2-phenoxyethanol 6.1
dUDP 6.1
5-Aza-2'-deoxycytidine 6.1
Ribose 6.1
Microcystin-LR 6.1
Z-Gly 6.0
NOXA 6.0
Cidofovir 6.0
Tetrandrine 6.0
Tetrandrine 6.0
Tetrandrine 6.0
Tetrandrine 6.0
Oxymatrine 6.0
benzo[c]phenanthridine 6.0
3-chlorophenol 5.9
Topotecan 5.9
TFT 5.9
Hyperforin 5.9
Prodigiosin 5.9
Prodigiosin 5.9
UDMA 5.9
1,2,4-benzenetriol 5.8
Carcinogen 5.8
TFF 5.8
Methoxychlor 5.8
Cordycepin 5.8
Cordycepin 5.8
Cordycepin 5.7
Methylparaben 5.7
Carnosic acid 5.7
Honokiol 5.7
alpha-Naphthoflavone 5.7
alpha-Naphthoflavone 5.7
PCB 126 5.7
Phorbol-12-myristate-13-acetate 5.6
alpha-Naphthoflavone 5.6
Isoliquiritigenin 5.6
Triptolide 5.6
Sitosterol 5.6
2-Methoxyestradiol 5.6
Paeonol 5.6
[1,10]phenanthroline 5.6
PAR 5.6
Gatifloxacin 5.6
Withaferin A 5.5
Ginsenoside Rg1 5.5
8-quinolinol 5.5
BLM 5.4
Sanguinarine 5.4
Fucoxanthin 5.4
Topotecan 5.4
Sulforaphane 5.4
Dehydroascorbic acid 5.3
SHB 5.3
ICRF-187 5.3
Pyrogallol 5.3
10-formyltetrahydrofolate 5.3
Oridonin 5.3
Ochratoxin A 5.3
Serine 5.3
Tempol 5.3
VP-16 5.3
Tauroursodeoxycholic acid 5.3
Norethisterone 5.2
8-quinolinol 5.2
GAR 5.2
CDT 5.2
SN-38 5.2
Pyrrolizidine 5.2
Salinomycin 5.2
Luteolin 5.2
Plumbagin 5.2
DHF 5.1
Gemcitabine 5.1
Aphidicolin 5.1
Aphidicolin 5.1
MNNG 5.1
Gemcitabine 5.1
(-)-Epigallocatechin 5.1
Matrine 5.1
Matrine 5.1
Matrine 5.1
EBT 5.1
iodoform 5.1
DNA 5.1
Mesna 5.0
N-acetylcysteine 5.0
Uracil 5.0
1H-indazole 5.0
HBC 5.0
Geldanamycin 5.0
MIA 5.0
ADR 5.0
Shikonin 5.0
[1,10]phenanthroline 5.0
PALA 4.9
Epigallocatechin gallate 4.9
BNP 4.9
Emodin 4.9
Allyl isothiocyanate 4.9
5H-pyrido[4,3-b]indole 4.9
diacetate 4.9
Tocopherols 4.9
TCH 4.9
DAC 4.8
Bis-GMA 4.8
Hydroxyurea 4.8
Chlorambucil 4.8
serine 4.8
Cypermethrin 4.8
phthalazine 4.7
Psoralen 4.7
Adriamycin 4.7
3-aminobenzamide 4.7
Mitoxantrone 4.7
Hesperidin 4.7
DHC 4.7
DPI 4.6
Mitoxantrone 4.6
3-(dimethylamino)propyl 4.6
Sulindac 4.6
Hoechst 33342 4.6
Cyd 4.6
Sodium azide 4.6
Piperine 4.6
Bisphenol A 4.6
Bisphenol A 4.6
glutaryl-CoA 4.6
Valproic acid 4.6
dUTP 4.5
Thymoquinone 4.5
Ethidium bromide 4.5
BAF 4.5
Lovastatin 4.5
CoM 4.5
N-methylacetamide 4.5
DIM 4.5
Benzo[a]pyrene 4.5
Ruthenium 4.5
Ruthenium 4.5
Resveratrol 4.4
hydroquinone 4.4
Apigenin 4.4
CPT-11 4.4
HEMA 4.4
MTS 4.4
phenanthridine 4.4
HEI 4.4
phenanthridine 4.4
phenanthridine 4.4
oxetane 4.4
DEK 4.4
trifluoroacetic anhydride 4.4
MCE 4.4
Deltamethrin 4.4
Ellagic acid 4.4
Cu2O 4.4
Nonylphenol 4.3
8-MOP 4.3
pentadecanoic acid 4.3
DLA 4.3
Puerarin 4.3
XTT 4.3
pentadecanoic acid 4.3
Morin 4.2
MES 4.2
MES 4.2
PDQ 4.2
5-Azacytidine 4.2
Pyruvate kinase 4.2
CAN 4.2
nonanoic acid 4.2
Iodo 4.2
NBS 4.2
MMC 4.2
Fucoidan 4.2
MDA 4.1
Vanillin 4.1
2-chlorophenol 4.1
Celecoxib 4.1
Emodin 4.1
Baicalein 4.1
G11 4.1
2-chlorophenol 4.1
ATF 4.1
Thioredoxin 4.1
Lindane 4.1
dCTP 4.0
DDP 4.0
caffeine 4.0
MTT 4.0
Ara-C 3.9
m-AMSA 3.9
Ubiquitin 3.9
Anthocyanin 3.9
DETA 3.9
Chlorogenic acid 3.9
BCNU 3.8
Valproic acid 3.8
myricetin 3.8
CMK 3.8
Lutein 3.8
Pravastatin 3.8
Zearalenone 3.8
Deoxynivalenol 3.8
Isoform 3.8
DBD 3.7
Deoxyribonucleic acid 3.7
Arsenite 3.7
pyrene 3.7
Flavonoid 3.7
DSS 3.7
chalcone 3.7
TSC 3.7
2-(dimethylamino)ethyl 3.7
phosphoserine 3.7
2-(dimethylamino)ethyl 3.7
dUMP 3.6
Kainic acid 3.6
TET 3.6
TET 3.6
Kainic acid 3.6
CDH 3.6
MBT 3.6
SCC 3.6
DEN 3.6
triphenylphosphine 3.6
EPC 3.6
HSO 3.6
Acrolein 3.6
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