Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P16104 (H2AX)
 3,930 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
H2AX 3930
histone 1173
p53 711
ATM 606
Mol 448
53BP1 322
ATR 284
caspase-3 275
DNA-dependent protein kinase 262
Chk1 262
Sep 245
p21 233
PARP 209
BRCA1 209
Chk2 179
ataxia telangiectasia mutated 143
Rad51 134
RAD51 130
A-T 126
MDC1 123
more...
Disease
cancer 1156
ATM 706
tumor 634
breast cancer 201
carcinogenesis 130
tumorigenesis 108
carcinoma 104
tumor growth 102
lung cancer 92
leukemia 88
MCF 71
prostate cancer 69
glioblastoma 64
adenocarcinoma 63
colorectal cancer 62
glioma 59
hepatocellular carcinoma 58
colon cancer 58
melanoma 48
non-small cell lung cancer 48
more...
Symptom
collapse 22
ataxia 11
starvation 5
diarrhea 5
exhaustion 5
seizures 4
hyperoxia 4
overweight 3
hypothermia 3
pain 3
skin damage 3
respiratory distress 2
cerebellar ataxia 2
cough 1
discomfort 1
nausea 1
anesthesia 1
anorexia 1
vomiting 1
CSR 1
more...
Drug
ROS 99
lysine 69
Mutagen 57
caffeine 43
ascorbate 12
BLM 12
Etoposide 11
Dermatol 9
DNase I 8
Vorinostat 7
ZnO 6
Monit 6
Adriamycin 6
Oxaliplatin 6
Indomethacin 5
Arsenic trioxide 5
MAP 5
CPT-11 5
Bortezomib 5
Glutathione 5
more...
Enzyme
PARP 255
caspase-3 208
mitogen-activated protein kinase 117
protein kinase 112
topoisomerase 103
topoisomerase 96
ERK 84
superoxide dismutase 53
catalase 45
endonuclease 44
proteasome 37
cdc2 32
calcineurin 30
caspase-8 29
caspase-9 28
DNA polymerase 25
ATPase 22
luciferase 21
focal adhesion kinase 20
RNA polymerase 18
more...
Compound
DNA 3417
oxygen 355
Dec 265
serine 227
Histone 91
lysine 77
hydrogen 65
cysteine 62
MTT 62
ATP 58
MDA 53
threonine 52
ADP-ribose 51
ADP 45
water 45
TNF 45
N-acetylcysteine 44
caffeine 43
ADP 42
ADP 42
more...