Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P16104 (H2AX)
 3,930 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
H2AX 0.999
53BP1 0.020
ATM 0.016
MDC1 0.012
histone 0.008
DNA-dependent protein kinase 0.006
Chk1 0.006
Chk2 0.006
ataxia telangiectasia mutated 0.005
CHK2 0.003
ATR 0.003
NBS1 0.003
Rad51 0.003
RAD51 0.002
p53 binding protein 0.002
histone H2A 0.002
CHK1 0.002
RNF8 0.002
p53 0.002
H2A histone family member 0.002
MRE11 0.001
NFBD1 0.001
H2A.X 0.001
BRCA1 0.001
Ku70 0.001
A-T 0.001
PARP 0.001
Rad50 0.001
RNF168 0.001
Ku80 0.001
RPA32 0.001
p21 0.001
RAD50 0.001
NADPH oxidase 1 0.001
RPA2 0.000
H2A 0.000
PARP-1 0.000
histone protein 0.000
p202 0.000
caspase-3 0.000
SMC1 0.000
tumor suppressor p53-binding protein 1 0.000
H2AZ 0.000
X-ray radiation resistance associated 1 0.000
KIAA0638 0.000
Tripartite motif-containing protein 29 0.000
Histone H2B type 1-K 0.000
nucleolar localized protein 0.000
H2BFM 0.000
C20orf135 0.000
HIST3H2BB 0.000
Histone H2A type 1 0.000
QSCN6 0.000
phosphoinositide-3-kinase adaptor protein 1 0.000
MARP3 0.000
zinc finger protein 12 0.000
CtIP 0.000
SYCP3 0.000
Wip1 0.000
FANCD2 0.000
Histone H2A 0.000
RPA 0.000
BRIT1 0.000
PARP1 0.000
KIAA0170 0.000
RGPD6 0.000
ZNF506 0.000
CCDC84 0.000
GLB1L 0.000
eyes absent 2 0.000
CCDC99 0.000
Zinc finger protein 668 0.000
KRCC1 0.000
XRCC4 0.000
TRF2 0.000
PP6R3 0.000
CCDC98 0.000
Werner syndrome helicase 0.000
topoisomerase I 0.000
macroH2A1.2 0.000
Ku86 0.000
galactosidase, beta 1 0.000
C13orf34 0.000
FIGNL1 0.000
mitogen-activated protein kinase kinase kinase 9 0.000
testis-specific histone H2B 0.000
RAD52 motif 1 0.000
EBNA1BP2 0.000
histone H2A.2 0.000
poly(ADP-ribose) polymerase 0.000
DNA repair protein 0.000
TOPBP1 0.000
PTIP 0.000
WIP1 0.000
SYCP1 0.000
meiotic recombination 11 0.000
PUMA 0.000
INO80 0.000
ATM protein 0.000
histone H3 0.000
recombination repair protein 0.000
TMEM24 0.000
Kinase-related protein 0.000
zinc finger and SCAN domain containing 21 0.000
Eyes absent 2 0.000
sulfotransferase 1C2 0.000
Mediator of DNA damage checkpoint 1 0.000
MAP17 protein 0.000
Histone H1.2 0.000
LL5A 0.000
PP6R2 0.000
macroH2A2 0.000
H2A histone 0.000
HUS1 0.000
kinase-related protein 0.000
RAD54B 0.000
ATLD 0.000
BRCA2 and CDKN1A interacting protein 0.000
nuclear receptor binding protein 2 0.000
PRTFDC1 0.000
SPSB3 0.000
zinc finger protein 2 0.000
MIZF 0.000
ATP6V1D 0.000
DNAJC1 0.000
NRBP2 0.000
cell cycle checkpoint protein 0.000
TEX15 0.000
UBC13 0.000
Microcephalin 0.000
TIP60 0.000
DNA topoisomerase 2 0.000
ROS 0.000
PPP4R2 0.000
Hipk1 0.000
ARP8 0.000
topoisomerase II beta 0.000
histone H2A.1 0.000
CDC25C 0.000
PPM1D 0.000
KAP1 0.000
CDKN1A 0.000
PP4C 0.000
NEK4 0.000
RAP80 0.000
DNA ligase IV 0.000
nibrin 0.000
KU70 0.000
Arp5 0.000
PLRG1 0.000
PP6R1 0.000
Rev7p 0.000
ATR interacting protein 0.000
Tousled-like kinase 1 0.000
PCID2 0.000
HIST1H2AL 0.000
TopBP1 0.000
XLF 0.000
BRCC45 0.000
Ino80 0.000
more...
Disease
ATM 0.010
cancer 0.000
tumor 0.000
FHA 0.000
MCPH1 0.000
carcinogenesis 0.000
breast cancer 0.000
NBS 0.000
RS-SCID 0.000
glioblastoma 0.000
oral neoplasm 0.000
Fanconi 0.000
tumorigenesis 0.000
MCF 0.000
premature aging 0.000
Mammary adenocarcinoma 0.000
tumor growth 0.000
FANCJ 0.000
MYP3 0.000
Senile osteoporosis 0.000
WRN 0.000
WT3 0.000
XPF 0.000
XPD 0.000
neck neoplasm 0.000
HP1 0.000
colon cancer 0.000
lung cancer 0.000
glioma 0.000
Seckel syndrome 0.000
SCAN1 0.000
FANCN 0.000
FA2 0.000
BLM 0.000
non-small cell lung cancer 0.000
La Crosse encephalitis 0.000
Mandibuloacral dysplasia 0.000
radiation carcinogenesis 0.000
XP-A 0.000
DMAT 0.000
recurrent SCLC 0.000
FANCI 0.000
leukemia 0.000
prostate cancer 0.000
ovarian cancer 0.000
FANCD1 0.000
progeria 0.000
colorectal cancer 0.000
carcinoma 0.000
PML 0.000
xeroderma pigmentosum 0.000
glue sniffing 0.000
cervical cancer 0.000
Precancerous lesions 0.000
XPE 0.000
adenocarcinoma 0.000
neoplastic transformation 0.000
osteosarcoma 0.000
glioblastoma multiforme 0.000
Cerebellar atrophy 0.000
PSN 0.000
roseola 0.000
pancreatic cancer 0.000
testicular embryonal carcinoma 0.000
CREST 0.000
SCA17 0.000
BMH 0.000
tumor progression 0.000
hepatocellular carcinoma 0.000
XPB 0.000
PBD 0.000
SCID 0.000
CSB 0.000
ABC-DLBCL 0.000
CSB 0.000
environmental carcinogenesis 0.000
retinoblastoma 0.000
Mucolipidosis type IV 0.000
Cockayne syndrome 0.000
HCC 0.000
Taybi 0.000
Dental fluorosis 0.000
acute myeloid leukemia 0.000
endocrine cancer 0.000
melanoma 0.000
trisomy 15 0.000
optic nerve glioma 0.000
Silence 0.000
chronic lymphocytic leukemia 0.000
B-cell lymphoma 0.000
relapsed CLL 0.000
metastatic cervical cancer 0.000
testicular atrophy 0.000
chronic lymphocytic leukemia 0.000
Glioblastoma 0.000
esophageal cancer 0.000
squamous cell carcinoma 0.000
esophageal cancer 0.000
genetic disorder 0.000
trichothiodystrophy 0.000
ATRX 0.000
carcinoma of the tongue 0.000
lymphoma 0.000
Fibrosarcoma 0.000
Ovary 0.000
HNSCC 0.000
Postoperative cognitive dysfunction 0.000
acute promyelocytic leukemia 0.000
CDT 0.000
liver cancer 0.000
Testicular torsion 0.000
neuroblastoma 0.000
LCS 0.000
lung carcinoma 0.000
Chemoradiation 0.000
T-cell acute lymphoblastic leukemia 0.000
XPG 0.000
Middle cerebral artery occlusion 0.000
Barrett's esophagus 0.000
Blocking 0.000
Esophageal squamous cell carcinoma 0.000
anemia 0.000
MTS 0.000
CEP 0.000
skin cancer 0.000
Selenium deficiency 0.000
bladder cancer 0.000
DSS 0.000
FRAXA 0.000
EMT 0.000
Shigella boydii 0.000
malignant meningioma 0.000
Rhabdomyosarcoma 0.000
Spitz nevus 0.000
AGS 0.000
myeloid leukemia 0.000
vaginal cancer 0.000
GSH 0.000
DDP 0.000
MIN 0.000
MIN 0.000
oral cancer 0.000
DSS 0.000
HOS 0.000
RSS 0.000
SMC 0.000
HGF 0.000
sarcoma 0.000
BFR 0.000
tobacco abuse 0.000
mantle cell lymphoma 0.000
BPP 0.000
fibrosarcoma 0.000
Ovary 0.000
CIN 0.000
Leukemia 0.000
Melanoma 0.000
immunotoxicity 0.000
malignant mesothelioma 0.000
Desmoplastic small round cell tumor 0.000
more...
Symptom
collapse 0.000
skin damage 0.000
ataxia 0.000
Halo 0.000
CSR 0.000
hyperoxia 0.000
exhaustion 0.000
cerebellar ataxia 0.000
bradykinesia 0.000
starvation 0.000
hypothermia 0.000
diarrhea 0.000
overweight 0.000
respiratory distress 0.000
splenomegaly 0.000
thinning 0.000
seizures 0.000
erythema 0.000
anorexia 0.000
acidity 0.000
discomfort 0.000
nausea 0.000
cough 0.000
discomfort 0.000
vomiting 0.000
fatigue 0.000
pain 0.000
anesthesia 0.000
Drug
Mutagen 0.000
ROS 0.000
Irofulven 0.000
Vorinostat 0.000
Tricyclazole 0.000
Adozelesin 0.000
Etoposide 0.000
BLM 0.000
Trabectedin 0.000
caffeine 0.000
lysine 0.000
Epalrestat 0.000
Crotonaldehyde 0.000
Sodium ascorbate 0.000
Tipifarnib 0.000
Oxaliplatin 0.000
Ciglitazone 0.000
Truvada 0.000
Tolfenamic acid 0.000
7-Nitroindazole 0.000
Tirapazamine 0.000
Mizoribine 0.000
Neocarzinostatin 0.000
TFT 0.000
Sesamol 0.000
Cidofovir 0.000
Areca 0.000
PFT 0.000
Hyperforin 0.000
Saha 0.000
Myricetin 0.000
Clofarabine 0.000
Arsenic trioxide 0.000
Artesunate 0.000
Panitumumab 0.000
Bortezomib 0.000
Podophyllum 0.000
2-Methoxyestradiol 0.000
Dexrazoxane 0.000
Truvada 0.000
Gatifloxacin 0.000
Gemzar 0.000
Mitomycin-C 0.000
CPT-11 0.000
Tolvaptan 0.000
Entecavir 0.000
Entecavir 0.000
Dihydro 0.000
Cytidine 0.000
Ammonium chloride 0.000
Propidium 0.000
Levovist 0.000
Taxotere 0.000
Silica gel 0.000
Erlotinib 0.000
Rosiglitazone 0.000
Irinotecan 0.000
Adriamycin 0.000
MRC 0.000
balanced salt solution 0.000
DNase I 0.000
ETS 0.000
Cetuximab 0.000
Aminoguanidine 0.000
NVP 0.000
TTC 0.000
Emodin 0.000
ADR 0.000
-deoxyadenosine 0.000
Troglitazone 0.000
ascorbate 0.000
Herceptin 0.000
Emodin 0.000
ZnCl2 0.000
ZnCl2 0.000
Lovastatin 0.000
Glutathione 0.000
Dasatinib 0.000
VCR 0.000
Kainic acid 0.000
Sorafenib 0.000
Everolimus 0.000
GEO 0.000
Indomethacin 0.000
Docetaxel 0.000
Zoledronic acid 0.000
Pravastatin 0.000
HCH 0.000
DBS 0.000
Check 0.000
Gastro 0.000
Reserpine 0.000
G418 0.000
PFA 0.000
CTC 0.000
AraC 0.000
Imatinib 0.000
ZnO 0.000
DMAP 0.000
Nitric Oxide 0.000
AZT 0.000
Vitamin B 0.000
CTC 0.000
MOF 0.000
AZT 0.000
Gleevec 0.000
Vitamin E 0.000
VCR 0.000
TAC 0.000
MAP 0.000
Parkin 0.000
Parkin 0.000
Albumin 0.000
ACT 0.000
Paraffin 0.000
Estrogens 0.000
Fragment 0.000
G-CSF 0.000
Silica 0.000
TAT 0.000
CTX 0.000
Fraction 0.000
Forskolin 0.000
Fluorescein 0.000
Alanine 0.000
ALA 0.000
TiO2 0.000
Monit 0.000
Rituximab 0.000
Heme 0.000
Taxol 0.000
Gel 0.000
Fluorescein 0.000
ENT 0.000
p75 0.000
PCB 0.000
vitamin E 0.000
Angiotensin II 0.000
NADH 0.000
FAD 0.000
CAM 0.000
Bifidobacterium 0.000
PTH 0.000
NH3 0.000
EPA 0.000
ampicillin 0.000
CSF 0.000
ROC 0.000
EE2 0.000
THF 0.000
Leaf 0.000
Ethanol 0.000
Dermatol 0.000
lactose 0.000
Nephron 0.000
IL-2 0.000
Cardiovasc 0.000
Enzyme
PARP 0.001
caspase-3 0.000
topoisomerase 0.000
topoisomerase 0.000
CYP39A1 0.000
protein kinase 0.000
mitogen-activated protein kinase 0.000
caspase-8 0.000
cdc2 0.000
caspase-9 0.000
endonuclease 0.000
histone acetyltransferase 0.000
caspase-2 0.000
caspase-2 0.000
ERK 0.000
DNA ligase 0.000
DNA ligase 0.000
RNase D 0.000
10-formyltetrahydrofolate dehydrogenase 0.000
calcineurin 0.000
protein phosphatase 2A 0.000
caspase-7 0.000
caspase-7 0.000
proteasome 0.000
CSAD 0.000
superoxide dismutase 0.000
ribonucleotide reductase 0.000
ribonucleotide reductase 0.000
DNA polymerase 0.000
DNA methyltransferase 0.000
catalase 0.000
polo-like kinase 1 0.000
CYP7B1 0.000
nicotinamide mononucleotide adenylyltransferase 0.000
endodeoxyribonuclease 0.000
phosphoinositide 3-kinase 0.000
deoxyguanosine kinase 0.000
NQO1 0.000
arachidonate 5-lipoxygenase 0.000
caspase-4 0.000
glutathione synthetase 0.000
caspase-4 0.000
carboxypeptidase G2 0.000
cytosine deaminase 0.000
CEP 0.000
valyl-tRNA synthetase 0.000
ubiquitin-protein ligase 0.000
MEK 0.000
beta-galactosidase 0.000
hypoxanthine-guanine phosphoribosyltransferase 0.000
STK11 0.000
poly(ADP-ribose) glycohydrolase 0.000
endonuclease VII 0.000
PHD 0.000
DCF 0.000
O-GlcNAc transferase 0.000
dihydroorotate dehydrogenase 0.000
ALDH 0.000
dihydroorotate dehydrogenase 0.000
phosphatidylinositol 3-kinase 0.000
phosphatidylethanolamine N-methyltransferase 0.000
methylthioadenosine phosphorylase 0.000
guanase 0.000
GAR 0.000
isopeptidase 0.000
pyruvate oxidase 0.000
pyruvate oxidase 0.000
thioredoxin reductase 0.000
CEP 0.000
thymidylate synthase 0.000
AMP-activated protein kinase 0.000
AMPK 0.000
micrococcal nuclease 0.000
deoxycytidine kinase 0.000
luciferase 0.000
Fpg protein 0.000
Lys4 0.000
RNA polymerase 0.000
biotinidase 0.000
focal adhesion kinase 0.000
3'-exonuclease 0.000
HCS 0.000
histone demethylase 0.000
GSK 0.000
cytidine deaminase 0.000
angiotensin-converting enzyme 2 0.000
farnesyltransferase 0.000
caspase-6 0.000
ATPase 0.000
cathepsin S 0.000
caspase-6 0.000
asparagine synthetase 0.000
xanthine dehydrogenase 0.000
HK2 0.000
prenyltransferase 0.000
CDH 0.000
1-hydroxylase 0.000
serine hydroxymethyltransferase 0.000
prenyltransferase 0.000
MTD 0.000
HDR 0.000
glutathione peroxidase 0.000
AMPK 0.000
prenyltransferase 0.000
DNase 0.000
gamma-glutamylcysteine synthetase 0.000
factor C 0.000
porphobilinogen deaminase 0.000
deoxyribonuclease 0.000
peroxiredoxin 0.000
MAT 0.000
cathepsin B 0.000
farnesyltransferase 0.000
polynucleotide kinase 0.000
lactate dehydrogenase 0.000
adenine phosphoribosyltransferase 0.000
MAT 0.000
MAP 0.000
methionine synthase 0.000
MPP 0.000
PST 0.000
TdT 0.000
PAT 0.000
PRE 0.000
KAT 0.000
demethylase 0.000
succinate dehydrogenase 0.000
Pla 0.000
IMP dehydrogenase 0.000
methionine synthase 0.000
cystathionine beta-synthase 0.000
matrix metalloproteinase 9 0.000
PDK1 0.000
nucleotidase 0.000
cathepsin D 0.000
thymidine phosphorylase 0.000
heme oxygenase 0.000
ECH 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
flavin-containing monooxygenase 0.000
3-hydroxy-3-methylglutaryl-CoA reductase 0.000
GRK5 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
thymidine kinase 0.000
NADPH oxidase 0.000
APC 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glutathione S-transferase 0.000
CPT 0.000
complex I 0.000
TPP 0.000
RNase 0.000
glucocerebrosidase 0.000
glutathione reductase 0.000
deoxyribonuclease 0.000
triphosphatase 0.000
apyrase 0.000
CPT 0.000
CYP3A4 0.000
more...
Compound
DNA 0.004
2-(4-chlorophenyl)benzo-1,4-quinone 0.000
Histone 0.000
Avenanthramide A 0.000
Eurycomalactone 0.000
serine 0.000
Ara-HA 0.000
2'-Hydroxychalcone 0.000
Microcephalin 0.000
ADP-ribose 0.000
Tebufenpyrad 0.000
8-OHdG 0.000
oxygen 0.000
Quinalizarin 0.000
Resmethrin 0.000
Hedamycin 0.000
methyl methanesulfonate 0.000
XPA 0.000
XPA 0.000
Aeroplysinin-1 0.000
Myosmine 0.000
Ovatodiolide 0.000
2,4-DMA 0.000
Angelicin 0.000
N-acetylcysteine 0.000
Butylidenephthalide 0.000
Saikosaponin A 0.000
Phosphoramide mustard 0.000
Rafoxanide 0.000
Myristicin 0.000
G 1 0.000
Solanine 0.000
MINA 0.000
Lanatoside C 0.000
Camptothecin 0.000
Camptothecin 0.000
Camptothecin 0.000
1H-benzo[de]isoquinoline-1,3(2H)-dione 0.000
Solanine 0.000
MTT 0.000
Chloranil 0.000
HN2 0.000
MDA 0.000
Plastoquinone 0.000
MTIC 0.000
Amentoflavone 0.000
Fostriecin 0.000
4-methoxybenzaldehyde 0.000
4-methoxybenzaldehyde 0.000
4-methoxybenzaldehyde 0.000
4-methoxybenzaldehyde 0.000
ADR 0.000
PAR 0.000
4-methoxybenzaldehyde 0.000
4-methoxybenzaldehyde 0.000
Adriamycin 0.000
BLM 0.000
diacetate 0.000
4-methoxybenzaldehyde 0.000
1,2,4-benzotriazine 0.000
Nitidine 0.000
caffeine 0.000
4-methoxybenzaldehyde 0.000
Serine 0.000
beta-Lapachone 0.000
4-methoxybenzaldehyde 0.000
7H-dibenzo[c,g]carbazole 0.000
VP-16 0.000
8-hydroxyguanosine 0.000
Diepoxybutane 0.000
Temozolomide 0.000
hydroxymethylbilane 0.000
Juglone 0.000
Methyleugenol 0.000
lysine 0.000
Phenanthrenequinone 0.000
dUTP 0.000
Anacardic acid 0.000
Dihydromyricetin 0.000
1,2-dichloropropane 0.000
threonine 0.000
Potassium bromate 0.000
5-Aza-2'-deoxycytidine 0.000
Carnosol 0.000
10-Hydroxycamptothecin 0.000
Bufalin 0.000
H2O2 0.000
pyrene 0.000
Nedaplatin 0.000
cysteine 0.000
ADP 0.000
ADP 0.000
ADP 0.000
hydrazinecarbothioamide 0.000
2-methylquinoline 0.000
PBD 0.000
Methacrylic acid 0.000
Azoxymethane 0.000
GRG 0.000
Ribose 0.000
Microcystin-LR 0.000
Propylparaben 0.000
MIA 0.000
Cepharanthine 0.000
NOXA 0.000
Trifluorothymidine 0.000
Calyculin A 0.000
2-methylquinoline 0.000
DMAE 0.000
hydroquinone 0.000
Topotecan 0.000
Gemcitabine 0.000
TIF 0.000
Hyperoside 0.000
Gemcitabine 0.000
Resveratrol 0.000
IBT 0.000
Neocarzinostatin 0.000
Cidofovir 0.000
Tetrandrine 0.000
Tetrandrine 0.000
Tetrandrine 0.000
iodine 0.000
Tetrandrine 0.000
Cyclopamine 0.000
DHM 0.000
Ochratoxin A 0.000
TNF 0.000
2-butenal 0.000
BNP 0.000
Bisphenol S 0.000
Sesamol 0.000
DDP 0.000
2-phenoxyethanol 0.000
TFT 0.000
dUDP 0.000
Dec 0.000
Sulforaphane 0.000
SN-38 0.000
Z-Gly 0.000
Triptolide 0.000
Carcinogen 0.000
Oxymatrine 0.000
benzo[c]phenanthridine 0.000
3-chlorophenol 0.000
Cordycepin 0.000
Cordycepin 0.000
Cordycepin 0.000
Hyperforin 0.000
Prodigiosin 0.000
Prodigiosin 0.000
Honokiol 0.000
UDMA 0.000
PCB 126 0.000
Topotecan 0.000
Hoechst 33342 0.000
1,2,4-benzenetriol 0.000
TFF 0.000
Bisphenol A 0.000
Bisphenol A 0.000
more...