Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P15088 (mast cell)
14,925 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mast cell 14925
IgE 2601
cytokine 1076
Sep 978
Mol 615
IL-4 560
c-kit 538
chymase 509
stem cell factor 472
IL-6 453
substance P 387
tumor necrosis factor 362
IL-3 350
TNF 341
collagen 321
KIT 295
TNF-alpha 262
IL-13 257
gut 250
IL-5 243
tyrosine kinase 223
IL-8 219
beta II 208
lymphoid 192
IL-10 180
chemokine 172
albumin 168
p38 168
mast cell tryptase 166
cyclooxygenase 158
CD4 141
bradykinin 136
chymotrypsin 135
lipopolysaccharide 133
interleukin-4 131
CD117 128
myeloperoxidase 125
PGD2 124
serum albumin 121
5-hydroxytryptamine 120
ATP 116
granulocyte 116
erythroid 115
serine protease 114
IL-33 113
ERK 112
proteoglycan 111
CD34 109
IFN-gamma 108
polypeptide 108
esterase 108
interferon 105
MAPK 105
histidine decarboxylase 104
IFN 103
fibronectin 102
IL-1 99
interleukin-6 96
LAD2 94
nerve growth factor 92
LPS 92
mast cell growth factor 91
IL-2 90
calcitonin 89
SDS 89
5-lipoxygenase 88
phosphatase 87
receptor tyrosine kinase 84
peroxidase 83
insulin 82
JNK 81
IL-9 80
membrane-bound 80
CD25 80
AMP 78
GM-CSF 77
vascular endothelial growth factor 77
thymus 76
CD8 75
PI3K 73
more...
Disease
asthma 1208
anaphylaxis 943
mastocytosis 917
tumor 817
cancer 513
leukemia 408
atopic dermatitis 330
mastocytoma 307
urticaria 263
pruritus 257
allergic rhinitis 245
eosinophilia 219
Mastocytosis 147
food allergy 143
dermatitis 139
urticaria pigmentosa 137
cold 131
Systemic mastocytosis 127
pertussis 122
ischemia 113
lymphoma 108
arthritis 107
skin disease 105
rheumatoid arthritis 103
allergic conjunctivitis 99
LAD2 94
rhinitis 92
interstitial cystitis 92
mast cell leukemia 90
SDS 89
sarcoma 88
diabetes 86
atherosclerosis 86
psoriasis 85
worms 84
carcinoma 84
inflammatory bowel disease 83
chronic urticaria 83
acute myeloid leukemia 81
irritable bowel syndrome 79
tumor growth 76
bronchospasm 76
multiple sclerosis 75
metastases 74
melanoma 72
plaque 71
conjunctiva 66
colitis 65
multiple myeloma 65
Evans 63
SEM 61
conjunctivitis 60
infectious diseases 60
tumorigenesis 60
bacterial infection 55
chronic myeloid leukemia 54
myeloproliferative disorders 54
hypertension 53
peritonitis 53
adenocarcinoma 53
uterus 52
myocardial infarction 52
carcinogenesis 51
keratoconjunctivitis 50
anemia 50
squamous cell carcinoma 50
PAF 50
autoimmune disease 49
vasculitis 49
Brown 48
ulcerative colitis 48
depression 47
NAME 47
tumor progression 46
migraine 44
myelodysplastic syndrome 44
virus infection 44
Infection 44
osteoporosis 42
breast cancer 42
more...
Symptom
pain 239
diarrhea 137
Welt 99
erythema 69
anesthesia 66
flushing 64
headache 53
sneezing 52
abdominal pain 50
collapse 44
vomiting 41
cough 39
splenomegaly 31
hypothermia 30
dyspnea 28
rhinorrhea 27
nausea 27
HSA 27
pelvic pain 25
nasal congestion 23
acute stress 22
hepatosplenomegaly 21
fatigue 20
wheezing 20
syncope 19
analgesia 18
spasm 17
discomfort 16
discomfort 16
bladder pain 16
angina 16
chest pain 16
respiratory distress 15
hepatomegaly 13
seizures 13
urinary frequency 12
bone pain 11
Darier's sign 9
sleepiness 8
starvation 8
chronic cough 8
constipation 8
thinning 7
skin damage 7
Gastrointestinal symptoms 7
functional recovery 5
Ear swelling 5
cyanosis 5
bloating 5
pallor 5
weakness 5
arthralgia 5
lethargy 5
tachypnea 5
postnasal drip 5
hyperoxia 5
Ill 4
acute pain 4
shortness of breath 4
stridor 4
heartburn 4
anorexia 4
dry skin 4
photophobia 4
tremor 4
nausea and vomiting 4
rundown 3
back pain 3
cancer pain 3
microbial colonization 3
hyperesthesia 3
hoarseness 3
dysuria 3
catarrh 3
dizziness 3
exhaustion 3
presyncope 3
myalgia 3
chest tightness 3
vestibulitis 3
more...
Drug
Dermatol 520
Histamine 374
Asthma 185
CSF 115
IFN-gamma 106
lysine 94
IL-2 93
Allergen 54
Ketotifen 45
CTX 43
Asn 43
Indomethacin 31
Imatinib 30
ABC 27
MAP 26
ROS 26
Omalizumab 25
Cardiovasc 25
Gel 23
L-tyrosine 17
Tranilast 16
Nedocromil sodium 15
Atropine 15
Gleevec 15
Diphenhydramine 15
Theophylline 14
vitamin E 13
Ethanol 13
Bifidobacterium 12
Cimetidine 12
Cimetidine 12
ETA 11
p75 11
G-CSF 11
ICI 10
Fluorescein 10
Salbutamol 9
Pronase 9
Leaf 9
lactose 9
Tacrolimus 8
DNase I 7
Prednisolone 7
CCL 7
Olopatadine hydrochloride 7
Midostaurin 7
IL-11 7
niacin 6
Paraffin 6
Fluorescein 6
Captopril 6
Angiotensin II 6
Ouabain 6
citric acid 6
Loratadine 6
TAT 5
Aprotinin 5
Propofol 5
EE2 5
Lodoxamide tromethamine 5
CaCl2 5
CaCl2 5
ascorbate 5
MEA 5
Budesonide 5
Patanol 5
CaCl2 5
Phosphatidylserine 5
PTH 4
Miltefosine 4
Dasatinib 4
balanced salt solution 4
-deoxyadenosine 4
Methylene blue 4
Reserpine 4
Mutagen 4
Ranitidine 4
Berberine sulfate 4
caffeine 4
Activin 4
more...
Enzyme
trypsin 1226
tryptase 1140
carboxypeptidase A 957
chymase 498
ERK 474
mitogen-activated protein kinase 361
hexosaminidase 289
peroxidase 227
protein kinase C 181
chymotrypsin 155
plasmin 122
histidine decarboxylase 113
focal adhesion kinase 106
protein kinase 101
phospholipase A2 100
elastase 93
phospholipase C 91
collagenase 81
carboxypeptidase B 74
lipoxygenase 73
thrombin 71
superoxide dismutase 71
cathepsin G 61
caspase-1 51
reverse transcriptase 49
lactate dehydrogenase 48
hyaluronidase 46
caspase-3 46
phosphatidylinositol 3-kinase 44
thermolysin 44
renin 43
pepsin 42
CD10 41
adenylate cyclase 41
phosphodiesterase 41
luciferase 41
lipase 41
ATPase 40
ACE 40
leucine aminopeptidase 39
calcineurin 38
NO synthase 36
CD13 35
catalase 35
MEK 33
lysozyme 32
kallikrein 31
phosphoinositide 3-kinase 31
beta-glucuronidase 30
alkaline phosphatase 30
papain 28
hyaluronidase 27
neutrophil elastase 27
proteasome 26
chondroitinase 26
neuraminidase 26
xanthine oxidase 26
BAL 25
RNase 24
chondroitinase 23
MIP 23
MAP 22
RNase 22
heparinase 22
APC 21
NADPH oxidase 20
diamine oxidase 20
granzyme B 20
RNA polymerase 19
subtilisin 19
cathepsin D 18
phospholipase D 17
CPN 16
acetylcholinesterase 16
NADPH oxidase 16
IKK 15
alpha-amylase 15
carboxypeptidase Y 15
sulfatase 15
matrix metalloproteinase 9 15
more...
Compound
calcium 1211
Dec 1002
Clin 937
tyrosine 486
sodium 459
Histamine 374
TNF 341
water 336
DNA 303
serine 303
acetate 290
arginine 276
Phe 241
zinc 239
oxygen 235
sulfate 218
nitric oxide 185
lysine 173
phosphate 155
PGD2 138
His 138
leucine 137
alanine 136
LTC4 133
ethanol 124
ATP 117
cAMP 109
Gly 105
DNP 103
5-HT 101
Asp 97
NH2 93
SDS 93
threonine 87
AMP 84
glucose 82
PGE2 81
hydrogen 79
salt 79
methionine 72
cysteine 71
potassium 68
PMA 67
PMA 66
Disodium cromoglycate 66
Substance P 63
bromide 61
Ile 61
Heparin 55
Adenosine 55
Toluidine blue 53
cobalt 52
formaldehyde 51
methylhistamine 51
acetic acid 50
EDTA 49
EDTA 49
tryptophan 49
galactose 48
nitrogen 46
Cardiol 46
iron 43
tryptophan 43
CTX 43
tryptophan 42
PGE 42
tryptophan 42
aldehyde 41
ASA 40
copper 39
CPA 38
CPA 38
CPA 38
GTP 38
CPA 38
urea 38
formaldehyde 37
methanol 36
HCl 36
aldehyde 35
more...