Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P15088 (
mast cell
)
14,925
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mast cell
14925
IgE
2601
cytokine
1076
Sep
978
Mol
615
IL-4
560
c-kit
538
chymase
509
stem cell factor
472
IL-6
453
substance P
387
tumor necrosis factor
362
IL-3
350
TNF
341
collagen
321
KIT
295
TNF-alpha
262
IL-13
257
gut
250
IL-5
243
tyrosine kinase
223
IL-8
219
beta II
208
lymphoid
192
IL-10
180
chemokine
172
albumin
168
p38
168
mast cell tryptase
166
cyclooxygenase
158
CD4
141
bradykinin
136
chymotrypsin
135
lipopolysaccharide
133
interleukin-4
131
CD117
128
myeloperoxidase
125
PGD2
124
serum albumin
121
5-hydroxytryptamine
120
ATP
116
granulocyte
116
erythroid
115
serine protease
114
IL-33
113
ERK
112
proteoglycan
111
CD34
109
IFN-gamma
108
polypeptide
108
esterase
108
interferon
105
MAPK
105
histidine decarboxylase
104
IFN
103
fibronectin
102
IL-1
99
interleukin-6
96
LAD2
94
nerve growth factor
92
LPS
92
mast cell growth factor
91
IL-2
90
calcitonin
89
SDS
89
5-lipoxygenase
88
phosphatase
87
receptor tyrosine kinase
84
peroxidase
83
insulin
82
JNK
81
IL-9
80
membrane-bound
80
CD25
80
AMP
78
GM-CSF
77
vascular endothelial growth factor
77
thymus
76
CD8
75
PI3K
73
more...
Disease
asthma
1208
anaphylaxis
943
mastocytosis
917
tumor
817
cancer
513
leukemia
408
atopic dermatitis
330
mastocytoma
307
urticaria
263
pruritus
257
allergic rhinitis
245
eosinophilia
219
Mastocytosis
147
food allergy
143
dermatitis
139
urticaria pigmentosa
137
cold
131
Systemic mastocytosis
127
pertussis
122
ischemia
113
lymphoma
108
arthritis
107
skin disease
105
rheumatoid arthritis
103
allergic conjunctivitis
99
LAD2
94
rhinitis
92
interstitial cystitis
92
mast cell leukemia
90
SDS
89
sarcoma
88
diabetes
86
atherosclerosis
86
psoriasis
85
worms
84
carcinoma
84
inflammatory bowel disease
83
chronic urticaria
83
acute myeloid leukemia
81
irritable bowel syndrome
79
tumor growth
76
bronchospasm
76
multiple sclerosis
75
metastases
74
melanoma
72
plaque
71
conjunctiva
66
colitis
65
multiple myeloma
65
Evans
63
SEM
61
conjunctivitis
60
infectious diseases
60
tumorigenesis
60
bacterial infection
55
chronic myeloid leukemia
54
myeloproliferative disorders
54
hypertension
53
peritonitis
53
adenocarcinoma
53
uterus
52
myocardial infarction
52
carcinogenesis
51
keratoconjunctivitis
50
anemia
50
squamous cell carcinoma
50
PAF
50
autoimmune disease
49
vasculitis
49
Brown
48
ulcerative colitis
48
depression
47
NAME
47
tumor progression
46
migraine
44
myelodysplastic syndrome
44
virus infection
44
Infection
44
osteoporosis
42
breast cancer
42
more...
Symptom
pain
239
diarrhea
137
Welt
99
erythema
69
anesthesia
66
flushing
64
headache
53
sneezing
52
abdominal pain
50
collapse
44
vomiting
41
cough
39
splenomegaly
31
hypothermia
30
dyspnea
28
rhinorrhea
27
nausea
27
HSA
27
pelvic pain
25
nasal congestion
23
acute stress
22
hepatosplenomegaly
21
fatigue
20
wheezing
20
syncope
19
analgesia
18
spasm
17
discomfort
16
discomfort
16
bladder pain
16
angina
16
chest pain
16
respiratory distress
15
hepatomegaly
13
seizures
13
urinary frequency
12
bone pain
11
Darier's sign
9
sleepiness
8
starvation
8
chronic cough
8
constipation
8
thinning
7
skin damage
7
Gastrointestinal symptoms
7
functional recovery
5
Ear swelling
5
cyanosis
5
bloating
5
pallor
5
weakness
5
arthralgia
5
lethargy
5
tachypnea
5
postnasal drip
5
hyperoxia
5
Ill
4
acute pain
4
shortness of breath
4
stridor
4
heartburn
4
anorexia
4
dry skin
4
photophobia
4
tremor
4
nausea and vomiting
4
rundown
3
back pain
3
cancer pain
3
microbial colonization
3
hyperesthesia
3
hoarseness
3
dysuria
3
catarrh
3
dizziness
3
exhaustion
3
presyncope
3
myalgia
3
chest tightness
3
vestibulitis
3
more...
Drug
Dermatol
520
Histamine
374
Asthma
185
CSF
115
IFN-gamma
106
lysine
94
IL-2
93
Allergen
54
Ketotifen
45
CTX
43
Asn
43
Indomethacin
31
Imatinib
30
ABC
27
MAP
26
ROS
26
Omalizumab
25
Cardiovasc
25
Gel
23
L-tyrosine
17
Tranilast
16
Nedocromil sodium
15
Atropine
15
Gleevec
15
Diphenhydramine
15
Theophylline
14
vitamin E
13
Ethanol
13
Bifidobacterium
12
Cimetidine
12
Cimetidine
12
ETA
11
p75
11
G-CSF
11
ICI
10
Fluorescein
10
Salbutamol
9
Pronase
9
Leaf
9
lactose
9
Tacrolimus
8
DNase I
7
Prednisolone
7
CCL
7
Olopatadine hydrochloride
7
Midostaurin
7
IL-11
7
niacin
6
Paraffin
6
Fluorescein
6
Captopril
6
Angiotensin II
6
Ouabain
6
citric acid
6
Loratadine
6
TAT
5
Aprotinin
5
Propofol
5
EE2
5
Lodoxamide tromethamine
5
CaCl2
5
CaCl2
5
ascorbate
5
MEA
5
Budesonide
5
Patanol
5
CaCl2
5
Phosphatidylserine
5
PTH
4
Miltefosine
4
Dasatinib
4
balanced salt solution
4
-deoxyadenosine
4
Methylene blue
4
Reserpine
4
Mutagen
4
Ranitidine
4
Berberine sulfate
4
caffeine
4
Activin
4
more...
Enzyme
trypsin
1226
tryptase
1140
carboxypeptidase A
957
chymase
498
ERK
474
mitogen-activated protein kinase
361
hexosaminidase
289
peroxidase
227
protein kinase C
181
chymotrypsin
155
plasmin
122
histidine decarboxylase
113
focal adhesion kinase
106
protein kinase
101
phospholipase A2
100
elastase
93
phospholipase C
91
collagenase
81
carboxypeptidase B
74
lipoxygenase
73
thrombin
71
superoxide dismutase
71
cathepsin G
61
caspase-1
51
reverse transcriptase
49
lactate dehydrogenase
48
hyaluronidase
46
caspase-3
46
phosphatidylinositol 3-kinase
44
thermolysin
44
renin
43
pepsin
42
CD10
41
adenylate cyclase
41
phosphodiesterase
41
luciferase
41
lipase
41
ATPase
40
ACE
40
leucine aminopeptidase
39
calcineurin
38
NO synthase
36
CD13
35
catalase
35
MEK
33
lysozyme
32
kallikrein
31
phosphoinositide 3-kinase
31
beta-glucuronidase
30
alkaline phosphatase
30
papain
28
hyaluronidase
27
neutrophil elastase
27
proteasome
26
chondroitinase
26
neuraminidase
26
xanthine oxidase
26
BAL
25
RNase
24
chondroitinase
23
MIP
23
MAP
22
RNase
22
heparinase
22
APC
21
NADPH oxidase
20
diamine oxidase
20
granzyme B
20
RNA polymerase
19
subtilisin
19
cathepsin D
18
phospholipase D
17
CPN
16
acetylcholinesterase
16
NADPH oxidase
16
IKK
15
alpha-amylase
15
carboxypeptidase Y
15
sulfatase
15
matrix metalloproteinase 9
15
more...
Compound
calcium
1211
Dec
1002
Clin
937
tyrosine
486
sodium
459
Histamine
374
TNF
341
water
336
DNA
303
serine
303
acetate
290
arginine
276
Phe
241
zinc
239
oxygen
235
sulfate
218
nitric oxide
185
lysine
173
phosphate
155
PGD2
138
His
138
leucine
137
alanine
136
LTC4
133
ethanol
124
ATP
117
cAMP
109
Gly
105
DNP
103
5-HT
101
Asp
97
NH2
93
SDS
93
threonine
87
AMP
84
glucose
82
PGE2
81
hydrogen
79
salt
79
methionine
72
cysteine
71
potassium
68
PMA
67
PMA
66
Disodium cromoglycate
66
Substance P
63
bromide
61
Ile
61
Heparin
55
Adenosine
55
Toluidine blue
53
cobalt
52
formaldehyde
51
methylhistamine
51
acetic acid
50
EDTA
49
EDTA
49
tryptophan
49
galactose
48
nitrogen
46
Cardiol
46
iron
43
tryptophan
43
CTX
43
tryptophan
42
PGE
42
tryptophan
42
aldehyde
41
ASA
40
copper
39
CPA
38
CPA
38
CPA
38
GTP
38
CPA
38
urea
38
formaldehyde
37
methanol
36
HCl
36
aldehyde
35
more...