Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P15088 (mast cell)
14,925 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mast cell 14925
IgE 2601
cytokine 1076
Sep 978
Mol 615
IL-4 560
c-kit 538
chymase 509
stem cell factor 472
IL-6 453
substance P 387
tumor necrosis factor 362
IL-3 350
TNF 341
collagen 321
KIT 295
TNF-alpha 262
IL-13 257
gut 250
IL-5 243
tyrosine kinase 223
IL-8 219
beta II 208
lymphoid 192
IL-10 180
chemokine 172
albumin 168
p38 168
mast cell tryptase 166
cyclooxygenase 158
CD4 141
bradykinin 136
chymotrypsin 135
lipopolysaccharide 133
interleukin-4 131
CD117 128
myeloperoxidase 125
PGD2 124
serum albumin 121
5-hydroxytryptamine 120
more...
Disease
asthma 1208
anaphylaxis 943
mastocytosis 917
tumor 817
cancer 513
leukemia 408
atopic dermatitis 330
mastocytoma 307
urticaria 263
pruritus 257
allergic rhinitis 245
eosinophilia 219
Mastocytosis 147
food allergy 143
dermatitis 139
urticaria pigmentosa 137
cold 131
Systemic mastocytosis 127
pertussis 122
ischemia 113
lymphoma 108
arthritis 107
skin disease 105
rheumatoid arthritis 103
allergic conjunctivitis 99
LAD2 94
interstitial cystitis 92
rhinitis 92
mast cell leukemia 90
SDS 89
sarcoma 88
atherosclerosis 86
diabetes 86
psoriasis 85
worms 84
carcinoma 84
inflammatory bowel disease 83
chronic urticaria 83
acute myeloid leukemia 81
irritable bowel syndrome 79
more...
Symptom
pain 239
diarrhea 137
Welt 99
erythema 69
anesthesia 66
flushing 64
headache 53
sneezing 52
abdominal pain 50
collapse 44
vomiting 41
cough 39
splenomegaly 31
hypothermia 30
dyspnea 28
rhinorrhea 27
nausea 27
HSA 27
pelvic pain 25
nasal congestion 23
acute stress 22
hepatosplenomegaly 21
fatigue 20
wheezing 20
syncope 19
analgesia 18
spasm 17
discomfort 16
chest pain 16
angina 16
discomfort 16
bladder pain 16
respiratory distress 15
hepatomegaly 13
seizures 13
urinary frequency 12
bone pain 11
Darier's sign 9
sleepiness 8
starvation 8
more...
Drug
Dermatol 520
Histamine 374
Asthma 185
CSF 115
IFN-gamma 106
lysine 94
IL-2 93
Allergen 54
Ketotifen 45
CTX 43
Asn 43
Indomethacin 31
Imatinib 30
ABC 27
ROS 26
MAP 26
Cardiovasc 25
Omalizumab 25
Gel 23
L-tyrosine 17
Tranilast 16
Atropine 15
Nedocromil sodium 15
Diphenhydramine 15
Gleevec 15
Theophylline 14
Ethanol 13
vitamin E 13
Bifidobacterium 12
Cimetidine 12
Cimetidine 12
G-CSF 11
p75 11
ETA 11
ICI 10
Fluorescein 10
Pronase 9
Salbutamol 9
Leaf 9
lactose 9
more...
Enzyme
trypsin 1226
tryptase 1140
carboxypeptidase A 957
chymase 498
ERK 474
mitogen-activated protein kinase 361
hexosaminidase 289
peroxidase 227
protein kinase C 181
chymotrypsin 155
plasmin 122
histidine decarboxylase 113
focal adhesion kinase 106
protein kinase 101
phospholipase A2 100
elastase 93
phospholipase C 91
collagenase 81
carboxypeptidase B 74
lipoxygenase 73
thrombin 71
superoxide dismutase 71
cathepsin G 61
caspase-1 51
reverse transcriptase 49
lactate dehydrogenase 48
hyaluronidase 46
caspase-3 46
thermolysin 44
phosphatidylinositol 3-kinase 44
renin 43
pepsin 42
CD10 41
adenylate cyclase 41
luciferase 41
phosphodiesterase 41
lipase 41
ACE 40
ATPase 40
leucine aminopeptidase 39
more...
Compound
calcium 1211
Dec 1002
Clin 937
tyrosine 486
sodium 459
Histamine 374
TNF 341
water 336
DNA 303
serine 303
acetate 290
arginine 276
Phe 241
zinc 239
oxygen 235
sulfate 218
nitric oxide 185
lysine 173
phosphate 155
PGD2 138
His 138
leucine 137
alanine 136
LTC4 133
ethanol 124
ATP 117
cAMP 109
Gly 105
DNP 103
5-HT 101
Asp 97
SDS 93
NH2 93
threonine 87
AMP 84
glucose 82
PGE2 81
salt 79
hydrogen 79
methionine 72
more...