Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P15088 (
mast cell
)
14,925
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mast cell
14925
IgE
2601
cytokine
1076
Sep
978
Mol
615
IL-4
560
c-kit
538
chymase
509
stem cell factor
472
IL-6
453
substance P
387
tumor necrosis factor
362
IL-3
350
TNF
341
collagen
321
KIT
295
TNF-alpha
262
IL-13
257
gut
250
IL-5
243
tyrosine kinase
223
IL-8
219
beta II
208
lymphoid
192
IL-10
180
chemokine
172
albumin
168
p38
168
mast cell tryptase
166
cyclooxygenase
158
CD4
141
bradykinin
136
chymotrypsin
135
lipopolysaccharide
133
interleukin-4
131
CD117
128
myeloperoxidase
125
PGD2
124
serum albumin
121
5-hydroxytryptamine
120
more...
Disease
asthma
1208
anaphylaxis
943
mastocytosis
917
tumor
817
cancer
513
leukemia
408
atopic dermatitis
330
mastocytoma
307
urticaria
263
pruritus
257
allergic rhinitis
245
eosinophilia
219
Mastocytosis
147
food allergy
143
dermatitis
139
urticaria pigmentosa
137
cold
131
Systemic mastocytosis
127
pertussis
122
ischemia
113
lymphoma
108
arthritis
107
skin disease
105
rheumatoid arthritis
103
allergic conjunctivitis
99
LAD2
94
interstitial cystitis
92
rhinitis
92
mast cell leukemia
90
SDS
89
sarcoma
88
atherosclerosis
86
diabetes
86
psoriasis
85
worms
84
carcinoma
84
inflammatory bowel disease
83
chronic urticaria
83
acute myeloid leukemia
81
irritable bowel syndrome
79
more...
Symptom
pain
239
diarrhea
137
Welt
99
erythema
69
anesthesia
66
flushing
64
headache
53
sneezing
52
abdominal pain
50
collapse
44
vomiting
41
cough
39
splenomegaly
31
hypothermia
30
dyspnea
28
rhinorrhea
27
nausea
27
HSA
27
pelvic pain
25
nasal congestion
23
acute stress
22
hepatosplenomegaly
21
fatigue
20
wheezing
20
syncope
19
analgesia
18
spasm
17
discomfort
16
chest pain
16
angina
16
discomfort
16
bladder pain
16
respiratory distress
15
hepatomegaly
13
seizures
13
urinary frequency
12
bone pain
11
Darier's sign
9
sleepiness
8
starvation
8
more...
Drug
Dermatol
520
Histamine
374
Asthma
185
CSF
115
IFN-gamma
106
lysine
94
IL-2
93
Allergen
54
Ketotifen
45
CTX
43
Asn
43
Indomethacin
31
Imatinib
30
ABC
27
ROS
26
MAP
26
Cardiovasc
25
Omalizumab
25
Gel
23
L-tyrosine
17
Tranilast
16
Atropine
15
Nedocromil sodium
15
Diphenhydramine
15
Gleevec
15
Theophylline
14
Ethanol
13
vitamin E
13
Bifidobacterium
12
Cimetidine
12
Cimetidine
12
G-CSF
11
p75
11
ETA
11
ICI
10
Fluorescein
10
Pronase
9
Salbutamol
9
Leaf
9
lactose
9
more...
Enzyme
trypsin
1226
tryptase
1140
carboxypeptidase A
957
chymase
498
ERK
474
mitogen-activated protein kinase
361
hexosaminidase
289
peroxidase
227
protein kinase C
181
chymotrypsin
155
plasmin
122
histidine decarboxylase
113
focal adhesion kinase
106
protein kinase
101
phospholipase A2
100
elastase
93
phospholipase C
91
collagenase
81
carboxypeptidase B
74
lipoxygenase
73
thrombin
71
superoxide dismutase
71
cathepsin G
61
caspase-1
51
reverse transcriptase
49
lactate dehydrogenase
48
hyaluronidase
46
caspase-3
46
thermolysin
44
phosphatidylinositol 3-kinase
44
renin
43
pepsin
42
CD10
41
adenylate cyclase
41
luciferase
41
phosphodiesterase
41
lipase
41
ACE
40
ATPase
40
leucine aminopeptidase
39
more...
Compound
calcium
1211
Dec
1002
Clin
937
tyrosine
486
sodium
459
Histamine
374
TNF
341
water
336
DNA
303
serine
303
acetate
290
arginine
276
Phe
241
zinc
239
oxygen
235
sulfate
218
nitric oxide
185
lysine
173
phosphate
155
PGD2
138
His
138
leucine
137
alanine
136
LTC4
133
ethanol
124
ATP
117
cAMP
109
Gly
105
DNP
103
5-HT
101
Asp
97
SDS
93
NH2
93
threonine
87
AMP
84
glucose
82
PGE2
81
salt
79
hydrogen
79
methionine
72
more...