Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P15088 (mast cell)
 14,925 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Generalized gingiva hyperplasia and multiple gingival masses were observed in an 8 year-old boxer dog. The masses were removed surgically. Three of them were biopsied. Microscopic examination was reported as fibrous gingival hyperplasia, fibrous epulis with osseous metaplasia, and mast cell tumor. Twenty-two months following surgery, moderate generalized gingival hyperplasia was present, with no clinical evidence of regrowth of the neoplasms.
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PMID:Simultaneous hyperplasia, metaplasia, and neoplasia in an 8 year-old boxer dog: a case report. 1196 30

Little is known about the physiological mechanisms related to low-intensity laser therapy (LILT), particularly in acute inflammation and subsequent wound healing. The objective of this study was to verify the effect of LILT on mast cell degranulation. Epulis fissuratum tissues from eight patients were used. One part of the lesion was irradiated with an AsGaAl laser (lambda = 670 nm, 8.0 J/cm(2), 5 mW, 4 min). The other part was not irradiated. Then, the specimens were immediately removed, fixed and examined by light microscopy. The number of mast cells was similar in laser-treated samples when compared with non-irradiated specimens. The degranulation indexes of the mast cells observed in the irradiated samples were significantly higher than those of controls (P < 0.05). LILT with the parameters used increased the number of degranulated mast cells in oral mucosa.
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PMID:Effect of low-intensity laser therapy on mast cell degranulation in human oral mucosa. 1808 8