Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P15088 (
mast cell
)
14,925
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This study examined levels of tryptase, a specific
mast cell
product, in synovial fluid. Samples of synovial fluid from eight patients with rheumatoid arthritis and ten with other arthritides were measured in solid-phase immunoradiometric assays. Elevated concentrations of tryptase were present in samples from three patients with rheumatoid arthritis, one with psoriasis, and one with
Reiter's syndrome
. The data support the theory that
mast cell
activation is involved in the pathogenesis in some inflammatory joint diseases, but activation does not appear to be disease specific.
...
PMID:Preliminary study of the tryptase levels in the synovial fluid of patients with inflammatory arthritis. 817 29
