Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P15088 (mast cell)
14,925 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Abundant degranulating mast cells were observed during an ultrastructural study of jejunal biopsy from an untreated patient with Whipple's disease. Some of these cells were observed in intimate contact with macrophages containing bacteria in various stages of disintegration. Thereafter bacilli were often seen within the cytoplasm of mast cells, enclosed within vacuoles. These findings are suggestive of a cooperation between mast cell and macrophage in the defence of the organism against Whipple's bacillus.
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PMID:Mast cells in Whipple's disease. 618 84