Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P14784 (IL-2 receptor)
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Human Gene/Protein
IL-2 receptor 13.0
90KD 12.0
SMAD 5 10.7
Tcr-alpha 10.7
CD132 10.7
NKTR 10.5
JAK3 protein 10.4
Interleukin-21 receptor 10.4
LC-PTP 10.3
IL2RB 10.1
aldesleukin 10.1
Interleukin 15 10.0
GPIA 10.0
25KD 9.8
YSA1 9.8
CD130 9.8
ILT5 9.7
BCL2-antagonist of cell death 9.7
IL15RA 9.7
CD125 9.7
CFIM 9.7
Interleukin 9 9.6
IL-2 protein 9.6
Jak3 9.6
Interleukin 2 9.6
KBF1 9.6
p55 9.6
induced upon T-cell activation 9.6
TARS 9.6
interleukin 2 receptor 9.5
CD53 antigen 9.4
ADP-ribosylation factor 3 9.4
CDC28 protein kinase regulatory subunit 1B 9.4
KAT3 9.3
IL-9R 9.3
5C5 9.3
p64 9.3
LY9 9.2
Interleukin-9 9.1
Rheb2 9.1
ATP binding cassette transporter 1 9.1
CD124 9.1
eomesodermin 9.0
pp21 9.0
interleukin 2 9.0
NRE-binding protein 8.9
anaphylatoxin C3a receptor 8.9
interleukin-2 8.9
IL2R 8.9
IL2RA 8.9
CD25 8.9
gamma chain 8.9
T-cell growth factor 8.8
p58.1 8.8
JAML 8.8
major histocompatibility class II antigen 8.8
IL-15 8.7
CIS1 8.7
DQw3.2 8.7
CaBP2 8.6
CD2BP2 8.6
HIV-EP1 8.6
coxsackie virus and adenovirus receptor 8.6
ltk 8.6
IL12R 8.6
IL-2 8.6
T cell growth factor 8.6
IL2RG 8.6
effector cell protease receptor-1 8.6
Interleukin-15 8.5
MTX2 8.5
T cell receptor gamma chain 8.4
CD69 antigen 8.4
FRA2 8.4
FIST 8.4
lymphocyte chemoattractant factor 8.4
CD8 antigen 8.3
Signal transducer and activator of transcription 4 8.3
alphaEbeta7 integrin 8.3
clone 18 8.3
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Disease
Decreased immune responsiveness 12.0
relapsed cutaneous T-cell lymphoma 11.4
Loffler's endocarditis 10.2
Lobular panniculitis 10.0
Melancholic depression 9.8
LFA-1 deficiency 9.7
X-linked severe combined immunodeficiency 9.6
Diffuse cutaneous leishmaniasis 9.5
cheilosis 8.6
metaphyseal dysostosis 8.5
Minimal change nephrotic syndrome 8.3
anal abscess 7.8
Chronic pyelonephritis 7.7
nodal marginal zone B-cell lymphoma 7.7
Subacute cutaneous lupus erythematosus 7.5
Drug-induced hypersensitivity syndrome 7.5
sclerokeratitis 7.5
inflamed eye 7.3
Systemic juvenile idiopathic arthritis 7.3
LGL leukemia 7.3
T cell neoplasms 7.2
T/NK-cell lymphoma 7.2
B-cell prolymphocytic leukemia 7.1
HTLV-I 7.1
adult T-cell leukemia/lymphoma 7.1
Colorectal adenocarcinoma 7.1
PHA 6.9
Chronic beryllium disease 6.9
Gram-positive bacteremia 6.9
EL4 6.9
Tubulointerstitial nephritis 6.5
BK virus nephropathy 6.5
prolymphocytic leukemia 6.5
angioendotheliomatosis 6.4
Stewart-Treves syndrome 6.4
cutaneous T-cell lymphoma 6.3
Sonne 6.2
loiasis 6.2
T-cell deficiency 6.2
Macrophage activation syndrome 6.0
hemophagocytic lymphohistiocytosis 6.0
radiation leukemia 5.9
Epidermolysis bullosa acquisita 5.9
Histiocytic necrotizing lymphadenitis 5.9
BCG infection 5.9
diphtheria 5.8
Lymphocytic infiltration 5.8
autoimmune lymphoproliferative syndrome 5.8
SCID 5.8
retroviral disease 5.7
adrenalitis 5.7
atypical mycobacterial infection 5.7
Aeromonas hydrophila infection 5.7
chronic eosinophilic leukemia 5.7
metastatic renal cell carcinoma 5.7
Pneumocystis jiroveci pneumonia 5.7
lymphocytosis 5.6
NOD 5.6
HAM 5.6
stage III melanoma 5.6
Dengue hemorrhagic fever 5.6
DHD 5.6
Pulmonary thromboembolism 5.6
FDC 5.6
Shwartzman reaction 5.6
DHD 5.6
Minimal change disease 5.6
lymphopenia 5.5
ADCC 5.5
congenital immunodeficiency 5.5
hairy cell leukemia 5.4
oophoritis 5.4
nasal allergy 5.4
interstitial keratitis 5.4
eosinopenia 5.3
Acute graft-versus-host disease 5.3
acute undifferentiated leukemia 5.3
HTX 5.3
thalassemia minor 5.2
immune deficiency 5.2
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Symptom
Opisthotonus 9.3
Flaccid paralysis 8.8
BHS 6.3
rigors 5.9
abdominal fullness 4.3
chills 4.1
dysesthesia 4.1
Decreased activity 4.0
adenitis 3.9
presyncope 3.8
neck stiffness 3.8
hepatosplenomegaly 3.7
limb pain 3.6
leg edema 3.6
paraparesis 3.6
splenomegaly 3.6
chest tightness 3.4
productive cough 2.9
abnormal gait 2.9
hypoproteinemia 2.9
decreased appetite 2.8
night sweats 2.8
asthenia 2.6
exertional dyspnea 2.3
exhaustion 2.3
neuralgia 2.2
cachexia 2.1
dysarthria 2.1
Depressive symptoms 2.1
fever of unknown origin 2.0
myalgia 1.9
nausea 1.8
wheezing 1.8
Ill 1.6
vomiting 1.5
hoarseness 1.5
bone pain 1.4
nausea and vomiting 1.4
erythema 1.3
epigastric pain 1.3
anorexia 1.3
arthralgia 1.2
neck pain 1.1
functional recovery 0.9
dyspnea 0.8
paresthesia 0.7
fatigue 0.7
numbness 0.7
lethargy 0.5
back pain 0.4
respiratory distress 0.3
headache 0.2
vertigo 0.2
cough 0.1
diarrhea 0.0
starvation -0.0
syncope -0.2
weakness -0.2
insomnia -0.4
agitation -0.5
sleepiness -0.6
ataxia -0.9
hypothermia -1.1
tremor -1.2
angina -1.4
seizures -1.7
anesthesia -1.7
collapse -1.8
abdominal pain -1.9
pain -2.2
Drug
Daclizumab 10.6
Amiprilose hydrochloride 10.4
Ontak 10.3
Ontak 10.3
Proleukin 9.9
Sizofiran 9.5
Loxoribine 9.4
Enisoprost 9.4
Cellcept 9.0
Azelastine hydrochloride 9.0
Cellcept 9.0
7,8-Dihydroneopterin 9.0
Basiliximab 8.8
Basiliximab 8.8
Glatiramer Acetate 8.8
IL-2 8.6
Mononine 8.4
Miocamycin 8.3
p75 7.7
Thymopentin 7.6
Leukine 7.6
LVFX 7.1
PAPM/BP 7.1
Swainsonine 6.6
TAC 6.5
Mizoribine 6.4
Novantrone 6.4
Isoprinosine 6.2
Belatacept 6.2
Anakinra 6.0
IFN-gamma 5.9
Interferon beta 5.8
Campath 5.8
Campath 5.8
Copaxone 5.7
anti-CD33 5.6
Tetanus toxoid 5.6
Bexarotene 5.6
Gastro 5.2
IL-1ra 5.2
Emodin 5.1
ID2 4.9
Bestatin 4.8
Pregnenolone 4.8
Emodin 4.8
Abciximab 4.8
Auranofin 4.6
Artesunate 4.6
Mycophenolic acid 4.6
Eculizumab 4.6
TRM 4.5
Ganciclovir 4.5
MDM 4.3
Tocilizumab 4.3
LCM 4.2
LCM 4.2
Trifluoperazine 4.2
Methylprednisolone 4.2
IFN-beta 4.0
Leucovorin 4.0
Dihydro 4.0
Neoral 4.0
Imiquimod 4.0
Adalimumab 4.0
CSF 3.9
Tacrolimus 3.9
IL-11 3.9
Tuberculin 3.8
G-CSF 3.7
Lovastatin 3.6
Phosphatidylserine 3.6
MRC 3.6
Adenosine deaminase 3.6
Prednisolone 3.5
G418 3.5
CIA 3.4
Zoledronic acid 3.4
PTC 3.2
Rituximab 3.1
Sodium nitroprusside 3.1
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Enzyme
DHAD 7.0
histone-lysine N-methyltransferase 7.0
Der p 1 6.2
SRR 5.9
granzyme B 5.9
prostasin 5.8
Thy1 5.8
deoxyhypusine synthase 5.7
TSP-1 5.6
ADP-ribosyltransferase 5.6
ADP-ribosyltransferase 5.6
glucosidase II 5.5
mannosidase II 5.4
lysophosphatidylcholine acyltransferase 5.0
p80 4.9
BMT 4.6
propionyl-CoA carboxylase 4.6
propionyl-CoA carboxylase 4.6
cathepsin H 4.5
galactose oxidase 4.3
factor D 4.2
p100 4.2
ricin 4.2
indoleamine 2,3-dioxygenase 4.1
HMG-CoA synthase 4.1
dipeptidyl peptidase IV 3.9
MTD 3.8
factor C 3.7
CD10 3.7
protein kinase C 3.6
type III procollagen 3.6
CD13 3.5
calcineurin 3.5
focal adhesion kinase 3.5
phosphatidylinositol 3-kinase 3.4
prolyl endopeptidase 3.4
PRA 3.3
arginine deiminase 3.3
sialidase 3.2
BMA 3.2
IMP dehydrogenase 3.2
endoglycosidase H 3.2
Rex 3.2
TdT 3.1
diacylglycerol kinase 3.1
BAL 3.1
carboxylesterase 3.1
PTPase 3.0
chloramphenicol acetyltransferase 3.0
angiotensin-converting enzyme 2 3.0
S1 nuclease 2.8
MIP 2.8
reverse transcriptase 2.7
chymase 2.6
LPL 2.6
cdc2 2.6
tryptase 2.6
alpha-mannosidase 2.5
triphosphatase 2.4
thyroid peroxidase 2.4
MEK 2.3
caspase-8 2.3
adenosine deaminase 2.3
adenosine deaminase 2.3
tryptophan hydroxylase 2.2
phospholipase D 2.1
PRE 2.1
dihydrofolate reductase 2.1
DCF 2.1
CaMKII 2.0
APC 2.0
phospholipase C 2.0
neuraminidase 2.0
HIV-1 protease 2.0
ornithine decarboxylase 2.0
lactase 2.0
glutamate decarboxylase 1.9
phosphoglycerate kinase 1.9
PDK1 1.9
PARP 1.9
more...
Compound
Interleukin-2 9.6
AS-101 9.2
Tubulozole 8.7
Rufloxacin 8.1
Homotaurine 7.6
[6]-Gingerol 7.4
neopterin 7.3
6R-BH4 7.0
Castanospermine 6.7
BAF 6.7
D-Galactosamine 6.7
Cilag 6.6
Deoxyspergualin 6.5
Swainsonine 6.4
T11 6.4
B 5 6.3
NKT 6.2
Diethylcarbamazine 6.2
Mycophenolate mofetil 6.1
Thiorphan 6.1
Exotoxin 6.0
1-cyclohexene 6.0
INN 6.0
CD 3 5.9
AY9944 5.9
VLA 5.9
C10H8N2 5.9
Esculetin 5.8
DAB 5.8
6-Gingerol 5.8
Solu-Medrol 5.8
DBB 5.8
DCL 5.7
Leflunomide 5.7
Phorbol-12-myristate-13-acetate 5.7
Paraformaldehyde 5.7
Bestatin 5.6
2-cyclopenten-1-one 5.5
Roxithromycin 5.4
Cyclosporine 5.4
Paraformaldehyde 5.3
PMA 5.3
F23 5.3
Herbimycin 5.2
Iodo 5.2
PPD 5.2
FK506 5.2
Deoxycoformycin 5.2
4-chlorobenzyl 5.2
1,1,2-trichloroethane 5.2
BBM 5.1
PPD 5.1
Emodin 5.1
EBT 5.1
Geldanamycin 5.0
Phorbol 5.0
MIBK 5.0
Beryllium 5.0
2-methylpiperazine 5.0
Vitamin D3 5.0
Cyanogen bromide 4.9
HMS 4.8
Vitamin D3 4.8
Pregnenolone 4.8
Levofloxacin 4.8
AIB 4.8
NPR 4.8
Rapamycin 4.7
PGA1 4.7
IDC 4.7
DDA 4.7
PMA 4.7
DDA 4.7
DDA 4.7
Piperine 4.6
Biotin 4.6
CsF 4.6
Puromycin 4.6
M 2 4.5
Nitroprusside 4.5
more...