Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P11021 (BiP)
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Human Gene/Protein
C10orf2 protein 13.9
atlastin 3 13.9
BiP 13.9
hemoglobin alpha-2 13.9
SDF2-like protein 1 13.9
FK506-binding protein 23 13.9
DNAJC12 protein 13.9
alpha-1,4-N-acetylglucosaminyltransferase 13.9
Stromal cell-derived factor 2-like 1 13.9
MTJ1 13.1
deubiquitinating enzyme 1 12.9
mitochondrial ubiquitin ligase activator of NFKB 1 12.9
ERdj3 12.7
FKBP23 12.7
ERdj5 12.5
SDF2L1 12.5
SIL1 12.5
dnaK-type molecular chaperone 12.3
histone H2B.1 12.3
skeletal muscle and kidney enriched inositol phosphatase 12.3
Membrane metallo-endopeptidase 12.3
MME protein 12.3
Calcium-binding protein 3 12.3
vitrin 12.3
cytochrome b5 reductase-like 12.3
JPDI 12.3
STCH 12.1
DNAJC10 11.9
glucose-regulated protein, 78kDa 11.9
eIF-2-alpha 11.9
ERp72 11.8
HYPE 11.8
SEC61A1 11.8
endoplasmic reticulum chaperone 11.7
EDEM 11.7
Death-associated protein 1 11.6
HSPA5 protein 11.6
HSPA13 11.6
LMO-4 11.6
ZNF611 11.6
protein disulfide isomerase-related protein 11.6
ERP1 11.6
SLC35B1 11.6
GRP78 11.6
HSPA5 11.5
MDG-1 11.5
NCB5OR 11.5
RAMP4 11.3
26S protease regulatory subunit 7 11.3
B/K protein 11.3
DnaJ-like protein 11.3
GRP94 11.3
EDJ 11.2
SEC12 11.1
lymphoma proprotein convertase 11.1
UGGT 11.1
PDILT 11.1
calcium activated nucleotidase 1 11.1
PRKR-like endoplasmic reticulum kinase 11.1
eukaryotic translation initiation factor 2A 11.0
endoplasmin 11.0
SEC63 10.9
SEC61 10.9
Flotillin 1 10.9
IRE2 10.9
OSBPL9 10.9
tubulin, beta 10.9
Derlin-3 10.9
arginyltransferase 1 10.9
ribonuclease/angiogenin inhibitor 1 10.9
teratocarcinoma-derived growth factor 10.9
ATF6 10.9
Tisp40 10.8
Ubc6p 10.8
Grp170 10.8
XBP-1 10.8
JEM-1 10.8
CEBPA protein 10.8
RESP18 10.8
EDEM1 10.7
more...
Disease
RP17 10.8
Picornavirus infection 10.5
EDM1 9.4
Wolcott-Rallison syndrome 9.1
QPD 8.9
CRD1 8.5
Cyclic neutropenia 8.3
Hereditary tyrosinemia type I 8.1
Retinal damage 8.1
Pseudoachondroplasia 8.0
Colorectal adenocarcinoma 8.0
Vernet 7.9
Infection induced 7.8
ARP1 7.8
FIH 7.7
megalocytosis 7.5
hereditary sensory neuropathy 7.1
HRD 7.0
myelinopathy 7.0
familial Alzheimer disease 7.0
hypopharyngeal squamous cell carcinoma 7.0
PARK7 6.9
Neurodegenerative Disorders 6.8
Bateman 6.7
Central diabetes insipidus 6.7
GALT 6.6
XFS 6.4
Wolfram syndrome 6.3
Shiga 6.3
Burnett 6.2
HSP 6.2
gangliosidosis 6.1
severe congenital neutropenia 6.1
Acute infection 6.1
torsion dystonia 6.0
GS1 5.8
AAT deficiency 5.7
AOS 5.7
Silence 5.7
Pelizaeus-Merzbacher disease 5.7
hormone refractory prostate cancer 5.6
XPB 5.6
FHF 5.5
juvenile myoclonic epilepsy 5.5
LQT1 5.4
INS 5.4
Primary open-angle glaucoma 5.4
Ovary 5.4
AAA 5.4
MSS 5.4
APOB 5.4
HLA-B27 5.3
mannosidosis 5.3
PNET 5.3
Renal fibrosis 5.3
MODY 5.2
DYT1 5.1
CP1 5.1
Primary effusion lymphoma 5.0
pediatric brain tumor 4.9
PCD 4.9
chondrodysplasia 4.9
osteogenesis imperfecta 4.8
NCR 4.8
SCD 4.8
retinitis pigmentosa 4.8
PMT 4.7
Common variable immunodeficiency 4.7
recurrent ovarian cancer 4.7
tyrosinemia 4.7
Ovary 4.7
SPS 4.6
hemolytic uremic syndrome 4.5
Borna disease 4.5
hypergammaglobulinemia 4.5
kernicterus 4.5
WSN 4.5
WSN 4.5
Dystonia 4.5
cutis laxa 4.5
more...
Symptom
Scratch 5.3
cerebellar ataxia 4.1
starvation 4.1
polyuria 3.9
abnormal gait 3.8
hyperoxia 3.2
polydipsia 2.8
ataxia 2.8
neck pain 2.0
acute stress 1.8
cachexia 1.5
flushing 1.3
dystonia 0.9
collapse 0.7
dizziness 0.7
thinning 0.5
weakness 0.3
exhaustion 0.2
anorexia 0.2
diarrhea 0.1
tremor -0.2
seizures -1.4
pain -2.5
Drug
MT6 8.6
3-Methyladenine 8.1
PE2 7.7
Lacidipine 7.2
Celebrex 7.0
Lacidipine 6.9
NOV 6.2
Bortezomib 6.2
Thioridazine 6.0
Thyroglobulin 6.0
CER 5.8
DEL 5.5
ATV 5.4
Doyle 5.3
RFP 5.3
beta-Galactosidase 5.2
LCM 5.1
LCM 5.1
Epigallocatechin 5.1
Viagra 5.0
ISP 5.0
PFT 5.0
Troglitazone 4.9
Viagra 4.7
Parkin 4.6
Parkin 4.6
Pronase 4.6
CTA 4.5
Raloxifene 4.4
Erlotinib 4.4
ROS 4.1
Photofrin 4.1
Vitamin A 3.9
uPA 3.9
Propofol 3.9
CoCl2 3.6
CoCl2 3.6
Sorafenib 3.4
balanced salt solution 3.3
Ranitidine 3.3
MRC 3.2
Gelatin 3.2
TTC 3.1
CPT-11 3.0
ABC 2.8
G418 2.8
Capsicum 2.8
Fraction 2.6
Nitric Oxide 2.6
Glutathione 2.5
Retinoic acid 2.2
HCH 2.2
Asn 2.0
lysine 1.9
Portal 1.9
Biopolymers 1.9
MAP 1.6
ICI 1.5
Leaf 1.5
FAD 1.5
Gel 1.1
ENT 0.9
nitroglycerin 0.8
IFN-gamma 0.7
Ethanol 0.7
citric acid 0.7
NADH 0.5
TiO2 0.5
ascorbate 0.4
ZnO 0.2
lactose -0.1
Asthma -0.7
Monit -1.2
Dermatol -1.3
Enzyme
proprotein convertase 4 12.9
GDPase 10.1
caspase-4 9.5
caspase-4 9.3
carboxypeptidase S 9.3
protein disulfide-isomerase 9.2
glucosidase II 9.0
aggrecanase-1 9.0
methylenetetrahydrofolate dehydrogenase 8.8
phosphoethanolamine N-methyltransferase 8.7
rubber transferase 8.5
arginyltransferase 8.3
methylenetetrahydrofolate dehydrogenase 8.3
carboxypeptidase Y 7.8
3-oxoacid CoA-transferase 7.3
peptidyl-prolyl cis-trans isomerase 7.3
mannosidase I 7.2
sulfhydryl oxidase 7.0
endoglycosidase H 6.8
cruzipain 6.8
cyclohydrolase 6.7
caspase-7 6.7
caspase-7 6.7
UDP-glucosyltransferase 6.6
Omi/HtrA2 6.5
GD3 synthase 6.4
triose-phosphate isomerase 6.4
valyl-tRNA synthetase 6.3
transaldolase 6.3
lactase-phlorizin hydrolase 6.2
GM3 synthase 6.2
glutaryl-CoA dehydrogenase 6.2
inositol 3-kinase 6.1
eEF2 kinase 6.0
caspase-6 6.0
spermidine/spermine N1-acetyltransferase 6.0
caspase-6 6.0
S-adenosyl-L-homocysteine hydrolase 5.8
ADPase 5.8
p80 5.8
GalT 5.8
fumarylacetoacetate hydrolase 5.8
leucyl-tRNA synthetase 5.7
H,K-ATPase 5.7
chaperonin 5.6
UDP-glucose dehydrogenase 5.6
factor C 5.6
proteasome 5.6
disulfide reductase 5.5
beta-1,3-glucanase 5.5
PNL 5.5
caspase-9 5.5
beta-1,3-glucanase 5.5
caspase-11 5.5
folylpolyglutamate synthetase 5.5
caspase-11 5.5
proprotein convertase 5.4
glucocerebrosidase 5.4
legumain 5.3
mannosidase II 5.3
PMT 5.3
ubiquitin-protein ligase 5.3
caspase-3 5.2
SPT 5.1
lactic acid dehydrogenase 5.1
lactic acid dehydrogenase 5.0
cutinase 5.0
aequorin 5.0
N-acetylglucosaminyltransferase 4.9
TGT 4.9
phosphoribulokinase 4.9
carbonyl reductase 4.9
ATPase 4.9
furin 4.9
HtrA 4.8
PARP 4.8
isopeptidase 4.8
AMPK 4.8
RNase T1 4.7
enolase 4.7
more...
Compound
Gaillardin 10.5
3-phenylpropanamide 9.8
Tauroursodeoxycholic acid 9.5
Solanine 9.2
Anacardic acid 9.1
2-ethoxy-2-oxoethyl 9.1
Avarol 9.1
Solanine 9.0
4-phenylbutanoic acid 8.8
PPBP 8.4
Helenalin 8.4
Tunicamycin 8.3
BIP 8.2
Granulin 8.1
3-Methyladenine 8.1
2-cyclopenten-1-one 8.0
PEK 7.8
Vinclozolin 7.8
Tuberin 7.7
Castanospermine 7.7
WMO 7.6
Ingenol 7.6
Geldanamycin 7.5
12-hydroperoxyeicosatetraenoic acid 7.5
Nelfinavir 7.4
Homoharringtonine 7.4
ATF 7.3
Foscan 7.3
Copper sulfate 7.2
p-Coumaric acid 7.1
dUDP 7.0
Brefeldin A 7.0
Brefeldin A 7.0
Exotoxin 6.9
Lithocholic acid 6.8
Biochanin A 6.8
Thapsigargin 6.8
Carnosic acid 6.6
Isoliquiritigenin 6.6
Monocrotaline 6.4
NOXA 6.4
Dansyl 6.4
Benzalkonium chloride 6.3
Filipin 6.3
Genipin 6.3
UDP-glucose 6.2
Cyclopiazonic acid 6.2
Pentazocine 6.2
Diallyl 6.2
DTT 6.1
12(S)-HETE 6.1
DTT 6.1
Pentazocine 6.0
pentanal 5.9
trimethyllysine 5.9
pentanal 5.9
2-heptanone 5.9
2-heptanone 5.8
Deoxycholic acid 5.8
6-aminohexanoic acid 5.8
6-aminohexanoic acid 5.8
Leupeptin 5.8
BAP 5.8
Trimethylamine N-oxide 5.8
Carcinogen 5.7
PGJ2 5.7
PGA2 5.7
BEP 5.7
Hemin 5.6
Hemin 5.6
Hemin 5.6
Hemin 5.6
Fluo-3 5.6
Inositol 5.6
Celastrol 5.6
ADMA 5.5
Methamphetamine 5.5
Methimazole 5.5
MME 5.5
Hemin 5.5
more...