Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P11021 (BiP)
 2,049 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
BiP 2049
endoplasmic reticulum 1357
GRP78 517
CHOP 263
Mol 262
PERK 163
ATP 158
calnexin 132
Sep 130
ATPase 121
calreticulin 118
ATF6 117
caspase-3 112
glucose-regulated protein 96
GRP94 95
C/EBP homologous protein 88
proteasome 87
glycoprotein 87
protein disulfide isomerase 87
IRE1 86
HSP70 82
ATF4 81
polypeptide 72
XBP1 72
heat shock protein 59
insulin 57
PDI 55
XBP-1 51
JNK 51
ER protein 51
membrane protein 48
Bcl-2 47
CCAAT/enhancer-binding protein homologous protein 47
heavy chain 46
ubiquitin 42
ADP 42
hsp70 42
HSPA5 40
endoplasmic reticulum chaperone 40
p53 39
PKR 38
LC3 37
fused 33
activating transcription factor 6 33
mTOR 32
secretory protein 32
cytokine 32
transmembrane protein 31
cytochrome c 31
DnaJ 29
membrane-bound 29
caspase-9 28
p62 27
collagen 26
ERp72 26
p38 25
microsomal 25
Hsp40 25
lectin 24
SDS 24
ERdj3 23
ERp57 23
IgG3 22
EBP 22
PARP 22
ROS 21
HDEL 21
X-box binding protein 1 21
ATF 20
78 kDa 20
MAPK 20
activating transcription factor 4 19
proteasome inhibitor 19
TNF 19
GADD34 19
tumor necrosis factor 18
SIL1 18
GRP 18
thyroglobulin 17
endoplasmin 17
p21 17
IL-6 16
envelope protein 15
Nrf2 15
PI3K 15
GSH 15
LPS 15
ERK1 14
Calreticulin 14
caspase-8 14
eukaryotic translation initiation factor 14
disulfide isomerase 14
Hsp90 14
IRE 14
glucosyltransferase 14
annexin V 14
c-Jun 13
serine protease 13
Beclin-1 13
precursor protein 13
caspase 12 13
cytochrome 13
GTP 13
Calnexin 13
MDG-1 13
PDB 12
erythroid 12
integral membrane protein 12
mda-7 12
oxidoreductase 12
Bak 12
HSP 12
initiation factor 2 12
ERdj5 12
EDEM 12
ATG5 12
lipopolysaccharide 12
AKT 12
dimeric 12
vimentin 12
threonine 12
TOF 12
AMPK 11
reductase 11
calpain 11
prion 11
ATF3 10
poly(ADP-ribose) polymerase 10
thioredoxin 10
IL-24 10
amyloid precursor protein 10
BAX 10
calmodulin 10
HEK 10
axonal 10
ERN1 9
prion protein 9
androgen receptor 9
epidermal growth factor 9
signal recognition particle 9
interferon 9
P58 9
ERK 9
estrogen receptor 9
mitogen-activated protein 9
p97 9
AMP 9
cyclin D1 9
transthyretin 9
glutathione S-transferase 8
HSC70 8
ERp29 8
RNase 8
proinsulin 8
UTR 8
superoxide dismutase 8
amylase 8
p58 8
AAA 8
SOD 8
more...
Disease
cancer 154
tumor 109
diabetes 44
Alzheimer's disease 42
hepatocellular carcinoma 31
Shiga 25
tumor growth 24
SDS 24
obesity 23
neuroblastoma 22
multiple myeloma 21
melanoma 21
ischemia 21
Parkinson's disease 20
carcinoma 19
leukemia 18
prostate cancer 16
influenza 16
hepatitis C 16
infectious diseases 16
GSH 15
tumorigenesis 15
cold 14
breast cancer 14
cholera 14
type 2 diabetes 14
fatty liver 14
tumor progression 13
HSP 12
carcinogenesis 11
Infection 11
amyotrophic lateral sclerosis 11
HIV 11
cytomegalovirus 10
rheumatoid arthritis 10
virus infection 10
hyperglycemia 10
lymphoma 9
retinitis pigmentosa 9
arthritis 9
lung cancer 8
stroke 8
pancreatic cancer 8
abdominal aortic aneurysm 8
glioblastoma multiforme 8
dengue 8
stomatitis 8
AAA 8
Legionella 8
adenocarcinoma 8
Melanoma 8
colorectal cancer 7
atherosclerosis 7
dehydration 7
epilepsy 7
glioblastoma 7
liver disease 7
Huntington's disease 6
HLA-B27 6
hypertension 6
dysplasia 6
myopathy 6
B-cell lymphoma 6
osteoarthritis 6
glioma 6
AIDS 6
mammary tumor 6
hepatitis B 5
insulinoma 5
hemolytic uremic syndrome 5
liver cancer 5
diabetic nephropathy 5
type 1 diabetes 5
bacterial infection 5
immunodeficiency 5
acute pancreatitis 5
amyloidosis 5
plaque 5
osteogenesis imperfecta 5
squamous cell carcinoma 5
cognitive impairment 5
MCF 5
glucose intolerance 5
diabetes insipidus 5
colon cancer 5
non-small cell lung cancer 5
polyneuropathy 5
malaria 5
INS 4
dementia 4
neurological disease 4
colitis 4
rabies 4
brain tumor 4
hyperhomocysteinemia 4
Blocking 4
autoimmune disease 4
osteoporosis 4
myeloid leukemia 4
goiter 4
cataract 4
ovarian cancer 4
cervical cancer 4
fibrosarcoma 4
Gaucher disease 4
schizophrenia 4
cirrhosis 4
gastric cancer 4
cerebral ischemia 4
liver cancer 4
Ovary 3
FAS 3
retinoblastoma 3
metastases 3
asthma 3
Ovary 3
neuropathy 3
ankylosing spondylitis 3
Haemophilia 3
thymoma 3
Mycobacterium 3
mental retardation 3
herpes simplex 3
infertility 3
worms 3
renal disease 3
TEM 3
pancreatitis 3
osteosarcoma 3
chronic lymphocytic leukemia 3
TEM 3
renal ischemia 3
myocardial infarction 3
Charcot-Marie-Tooth disease 3
proteinuria 3
blindness 3
sepsis 3
mental retardation 3
cardiovascular disease 3
depression 3
polycystic kidney 3
arteriosclerosis 3
bipolar disorder 3
malnutrition 3
sepsis 3
leishmaniasis 3
neutropenia 3
parkinsonism 2
respiratory failure 2
tuberculosis 2
Age-related macular degeneration 2
lung disease 2
chronic obstructive pulmonary disease 2
renal failure 2
systemic lupus erythematosus 2
SCID 2
Wolcott-Rallison syndrome 2
memory impairment 2
peripheral neuropathy 2
chronic lymphocytic leukemia 2
more...
Symptom
starvation 27
ataxia 7
diarrhea 4
cerebellar ataxia 4
weakness 3
collapse 3
pain 3
polyuria 3
hyperoxia 3
seizures 2
dystonia 1
dizziness 1
Scratch 1
cachexia 1
anorexia 1
acute stress 1
polydipsia 1
neck pain 1
abnormal gait 1
exhaustion 1
tremor 1
flushing 1
thinning 1
Drug
ROS 21
lysine 14
Bortezomib 7
Dermatol 7
Leaf 4
ABC 4
Vitamin A 3
Parkin 3
Parkin 3
3-Methyladenine 3
MAP 3
PE2 3
Asn 3
IFN-gamma 3
RFP 3
Thyroglobulin 2
uPA 2
ascorbate 2
CTA 2
Gel 2
Pronase 2
NADH 2
Glutathione 2
MRC 2
Biopolymers 2
Propofol 2
NOV 1
ZnO 1
Lacidipine 1
Thioridazine 1
Celebrex 1
Troglitazone 1
citric acid 1
Doyle 1
LCM 1
Lacidipine 1
lactose 1
Nitric Oxide 1
CPT-11 1
CoCl2 1
TiO2 1
Viagra 1
CoCl2 1
PFT 1
HCH 1
Erlotinib 1
Sorafenib 1
DEL 1
beta-Galactosidase 1
CER 1
Viagra 1
ISP 1
Gelatin 1
Epigallocatechin 1
ICI 1
FAD 1
ENT 1
Monit 1
Retinoic acid 1
nitroglycerin 1
Portal 1
Raloxifene 1
Fraction 1
Photofrin 1
MT6 1
TTC 1
G418 1
balanced salt solution 1
ATV 1
Ethanol 1
Asthma 1
LCM 1
Capsicum 1
Ranitidine 1
Enzyme
ATPase 123
proteasome 87
caspase-3 86
mitogen-activated protein kinase 85
protein kinase 71
PARP 25
caspase-9 22
ERK 21
caspase-4 19
carboxypeptidase Y 18
AMP-activated protein kinase 15
caspase-4 15
RNase 14
glutathione S-transferase 14
superoxide dismutase 14
endoglycosidase H 13
RNase 13
luciferase 12
AMPK 11
AMPK 11
caspase-8 11
trypsin 11
MEK 10
peptidyl-prolyl cis-trans isomerase 8
focal adhesion kinase 8
catalase 8
alkaline phosphatase 8
beta-galactosidase 7
endonuclease 7
invertase 7
chaperonin 7
neuraminidase 7
alpha-glucosidase 6
enolase 6
ribonuclease 6
chymotrypsin 6
caspase-7 6
ribonuclease 6
cathepsin D 6
acid phosphatase 6
glucosidase II 6
protein disulfide-isomerase 6
furin 6
caspase-7 6
protein kinase C 5
lactate dehydrogenase 5
phospholipase C 5
ricin 5
calcineurin 5
monoamine oxidase 5
NO synthase 5
glyceraldehyde-3-phosphate dehydrogenase 5
cathepsin B 4
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
thrombin 4
glucocerebrosidase 4
phosphatidylinositol 3-kinase 4
aspartate aminotransferase 4
proteinase K 4
peroxidase 4
alpha-amylase 4
glyceraldehyde-3-phosphate dehydrogenase 4
beta-lactamase 4
beta-glucuronidase 4
glutathione peroxidase 4
peroxiredoxin 4
MMP 4
glyceraldehyde-3-phosphate dehydrogenase 4
lysozyme 4
tyrosinase 4
chitinase 4
glutamate dehydrogenase 3
MAP 3
neutrophil elastase 3
glutamate dehydrogenase 3
CaMKII 3
caspase-1 3
lipase 3
cruzipain 3
methylenetetrahydrofolate dehydrogenase 3
aequorin 3
topoisomerase 3
kinesin 3
proprotein convertase 3
ACS 3
subtilisin 3
topoisomerase 3
glutamate dehydrogenase 3
creatine kinase 3
NQO1 3
chloramphenicol acetyltransferase 3
carboxypeptidase S 3
methylenetetrahydrofolate dehydrogenase 3
acetyl-CoA carboxylase 3
cellulase 3
cyclohydrolase 3
ATP synthase 3
IKK 3
aldehyde dehydrogenase 2
lipoprotein lipase 2
aldehyde dehydrogenase 2
cytochrome oxidase 2
aldehyde dehydrogenase 2
sialyltransferase 2
mannosidase I 2
reverse transcriptase 2
sialyltransferase 2
sulfhydryl oxidase 2
CD10 2
pyruvate kinase 2
aggrecanase-1 2
carboxylesterase 2
beta-glucosidase 2
RNase T1 2
GDPase 2
6-phosphogluconate dehydrogenase 2
beta-1,3-glucanase 2
thromboplastin 2
firefly luciferase 2
heme oxygenase 2
6-phosphogluconate dehydrogenase 2
alanine aminotransferase 2
malate dehydrogenase 2
ubiquitin-protein ligase 2
tissue plasminogen activator 2
NADPH oxidase 2
phosphoinositide 3-kinase 2
Omi/HtrA2 2
urokinase-type plasminogen activator 2
carbonic anhydrase 2
prolyl hydroxylase 2
NADPH oxidase 2
p80 2
SPT 2
beta-1,3-glucanase 2
thyroid peroxidase 2
factor C 2
beta-glucosidase 2
alpha-mannosidase 2
alcohol dehydrogenase 2
transaldolase 2
SPC 2
sialyltransferase 2
thioredoxin reductase 2
collagenase 2
succinate dehydrogenase 2
caspase-6 2
aldehyde dehydrogenase 2
dihydrofolate reductase 2
ADPase 2
caspase-6 2
apyrase 2
aldehyde dehydrogenase 2
PHD 1
hydrogenase 1
elastase 1
PKG 1
cathepsin L 1
TdT 1
more...
Compound
ATP 158
Dec 149
calcium 145
glucose 123
DNA 117
oxygen 78
cysteine 49
ADP 44
ADP 42
ADP 42
water 28
COS 26
lysine 25
SDS 24
arginine 23
threonine 21
ATF 20
TNF 19
galactose 19
tyrosine 19
His 18
GSH 17
GSH 17
sodium 17
serine 17
leucine 16
Tunicamycin 15
alanine 15
Clin 15
phosphate 15
methionine 14
UDP-glucose 13
salt 13
nitric oxide 13
sulfate 13
GTP 13
palmitic acid 12
TOF 12
N-acetylcysteine 12
hydrogen 11
MTT 11
GSSG 11
cAMP 11
Tauroursodeoxycholic acid 10
homocysteine 10
cadmium 9
zinc 9
NH2 9
tryptophan 9
dUTP 9
iron 9
urea 9
ethanol 9
DTT 9
glutamate 9
AMP 9
DTT 9
AAA 8
tryptophan 8
palmitic acid 8
tryptophan 8
copper 8
tryptophan 8
MDA 8
Phe 8
Brefeldin A 7
acetate 7
Brefeldin A 7
Asp 7
ADP-ribose 6
Thapsigargin 6
glycerol 6
H2O2 6
asparagine 6
proline 6
glutamine 6
Gly 5
phenol 5
nitrogen 5
GABA 5
bromide 5
Methamphetamine 5
boron 5
BIP 5
Inositol 5
MEK 5
silver 5
manganese 5
GABA 5
Sucrose 5
ammonium 5
BCR 5
iodine 4
GlcNAc 4
ACS 4
THP 4
2-mercaptoethanol 4
Triton X-100 4
FK506 4
DMSO 4
DDP 4
PEG 4
butyric acid 4
THP 4
2-cyclopenten-1-one 3
CoA 3
NADPH 3
retinol 3
aldehyde 3
NAD 3
UDP 3
Melatonin 3
ACS 3
Epigallocatechin gallate 3
TEM 3
acridine 3
Vitamin A 3
Estrogen 3
Cardiol 3
Neuronal 3
butyric acid 3
Substance P 3
CdCl2 3
Rapamycin 3
pyrene 3
NAD 3
Austin 3
Mg2+ 3
valine 3
EDTA 3
retinoic acid 3
Geldanamycin 3
Panam 3
EDTA 3
glutamic acid 3
MAP 3
butyric acid 3
CHAPS 3
BAP 3
3-Methyladenine 3
aldehyde 3
NADPH 3
Cereb 3
Collagen 3
Pac 2
CCl4 2
TAP 2
hexose 2
Adenine 2
NADH 2
Fluo-3 2
Sodium 2
Anacardic acid 2
methyl methanesulfonate 2
GM1 2
Propofol 2
nitrate 2
hydroquinone 2
Ile 2
Pectin 2
more...