Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10721 (c-kit)
 6,575 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
c-kit 12.2
Mast cell growth factor 11.7
alpha-methyl-acyl-CoA racemase 11.2
HBEX2 11.2
Src-like-adaptor 11.2
H2B-GL105 11.2
exosome component 10 11.2
TFG-NR4A3 fusion 11.2
stem cell factor, SCF 11.2
zinc finger protein 16 11.2
ELKL motif kinase 11.2
H-RAS protein 11.2
Receptor protein tyrosine kinase 11.2
kit-ligand 10.7
stem cell tyrosine kinase 1 10.7
MITF-C 10.7
casein kinase-1 binding protein 10.7
EDRF1 10.7
apoptosis repressor with CARD domain 10.7
mast cell growth factor 10.5
stem cell factor 10.4
hematopoietic stem cell antigen 10.2
ZNF16 10.2
G protein-coupled receptor 125 10.2
FLT2 10.2
ABCC10 protein 10.2
KIT protein 10.2
stem cell growth factor 10.0
HSD17 9.9
GAGE-7 9.9
CD117 9.8
inhibin, alpha 9.7
chromobox homolog 8 9.7
HZF1 9.7
NAK-associated protein 1 9.7
PRDM7 9.7
fms-related tyrosine kinase 3 9.6
SR-1 9.5
MAGEB4 9.4
SAMD14 9.4
HMG20B 9.4
GDF-3 9.4
CRIP2 9.2
PH domain and leucine rich repeat protein phosphatase 9.2
YBX1 protein 9.2
STK-1 9.2
Spred-3 9.2
transcription factor Pax-5 9.2
MGF 9.1
POU domain class 5 transcription factor 1 9.1
ORP10 9.1
claudin 8 9.1
EPC-like 9.1
BRDG1 9.1
neurobeachin-like 2 9.1
CALM/AF10 fusion 9.1
TPSB2 9.1
STK1 9.0
platelet-derived growth factor receptor 8.9
POPDC2 8.9
Tyrosinase-related protein-2 8.9
MRD2 8.9
GIST 8.9
platelet-derived growth factor receptor alpha 8.9
placental-like alkaline phosphatase 8.9
CD150 8.9
MPP3 8.8
tyrosine kinase receptor 8.8
PDGFR 8.8
Flt3 ligand 8.8
Spred-1 8.8
microphtalmia-associated transcription factor 8.8
TAF4B 8.8
RNA-binding motif protein 15 8.8
SPINLW1 8.8
edg-2 8.8
ORP4 8.8
podocalyxin-like protein 8.7
Sal-like protein 4 8.7
MEK kinase 2 8.7
more...
Disease
Postmenopausal disorders 12.2
Reactive mastocytosis 12.2
Thymic epithelial neoplasm 11.2
adult brainstem glioma 11.2
Diabetic gastroenteropathy 11.2
Gastrointestinal stromal sarcoma 10.9
Spindle cell melanoma 10.8
Familial mastocytosis 10.7
Cutaneous mastocytosis 10.5
SM-AHNMD 10.4
Telangiectasia macularis eruptiva perstans 10.4
LFSS 10.2
HPC3 10.2
mast cell leukemia 9.7
untreated adult AML 9.7
Diffuse cutaneous mastocytosis 9.5
type B thymoma 9.4
CMML-2 9.4
CSPC 9.4
ECA3 9.2
gastrointestinal stromal tumor 9.2
Mastocytosis 9.2
stromal tumors 9.0
CNS germinoma 9.0
megasigmoid 8.9
mastocytosis 8.9
Adenoid basal carcinoma 8.8
Systemic mastocytosis 8.7
skin pigmentation disorder 8.5
Inflammatory fibroid polyp 8.5
Acute basophilic leukemia 8.4
childhood ependymoma 8.4
CIIP 8.4
trisomy 12q 8.3
neoplasm of uncertain malignant potential 8.3
urticaria pigmentosa 8.3
Vitiligo vulgaris 8.2
Undifferentiated sarcoma 8.2
Plexiform schwannoma 8.2
Infantile malignant osteopetrosis 8.1
Total colonic aganglionosis 8.1
Malignant granular cell tumor 7.9
Staphylococcus aureus abscess 7.9
CASTLE 7.9
refractory testicular cancer 7.8
PBT 7.6
Mesenteric fibromatosis 7.5
mastocytoma 7.5
Bile duct cancer 7.4
Leukemia stem cell 7.4
Mesoblastic nephroma 7.4
CASTLE 7.4
Chloroma 7.3
Gastric lymphoma 7.3
Landau-Kleffner syndrome 7.3
congenital anemia 7.2
hepatocholangiocarcinoma 7.2
plexiform schwannoma 7.1
FPD/AML 7.1
gallbladder empyema 7.1
Gastrointestinal Tumor 7.1
Spermatocytic seminoma 7.1
Riehl's melanosis 7.0
invasive lobular breast carcinoma 7.0
Adenomyoepithelioma 6.9
cHL 6.9
Adenomyoepithelioma 6.9
chronic eosinophilic leukemia 6.9
macrocytic anemia 6.9
Metastatic malignant melanoma 6.8
Diabetic gastroparesis 6.8
epithelial thymoma 6.8
thymic carcinoma 6.8
ICC 6.6
preneoplastic state 6.6
MDS/MPD 6.6
ICC 6.6
poliosis 6.6
congenital hypoplastic anemia 6.5
muscle neoplasm 6.5
more...
Symptom
Spotting 8.8
Darier's sign 8.2
female puberty 5.3
periorbital edema 5.3
dyschezia 4.4
anal pain 4.3
tenesmus 4.3
male subfertility 4.2
constipation 3.9
HSA 3.9
abdominal fullness 3.6
stomach pain 3.3
lightheadedness 3.2
splenomegaly 3.2
urinary frequency 3.1
abdominal discomfort 3.1
decreased appetite 3.0
abdominal pain 3.0
chronic constipation 2.9
acute abdominal pain 2.9
leg edema 2.8
flank pain 2.7
hepatosplenomegaly 2.7
functional recovery 2.7
bone pain 2.6
intestinal bleeding 2.6
consciousness disturbance 2.6
bloating 2.5
hip pain 2.4
flushing 2.4
DNA marker 2.4
pelvic pain 2.3
emaciation 2.2
anorexia 2.2
skin irritation 2.2
epigastric pain 2.1
dysuria 2.0
exhaustion 2.0
asthenia 1.9
nasal discharge 1.8
lethargy 1.8
hepatomegaly 1.7
nausea 1.7
hoarseness 1.7
acute abdomen 1.7
syncope 1.7
colic 1.6
hyperoxia 1.5
diarrhea 1.4
dizziness 1.3
back pain 1.3
fatigue 1.2
fever of unknown origin 1.2
vomiting 1.2
tense 1.2
polydipsia 1.1
thinning 1.1
numbness 0.9
dry eye 0.9
shoulder pain 0.8
polyuria 0.7
dyspnea 0.6
ophthalmoplegia 0.5
starvation 0.4
cerebellar ataxia 0.4
memory loss 0.4
discomfort 0.4
cyanosis 0.4
weakness 0.4
respiratory distress 0.3
acute pain 0.3
discomfort 0.2
chills 0.2
acute stress 0.1
nausea and vomiting 0.0
paresthesia -0.0
shortness of breath -0.1
collapse -0.2
chest pain -0.2
headache -0.4
more...
Drug
Tandutinib 10.4
Gleevec 9.4
Imatinib 9.0
Hymenialdisine 8.9
Lestaurtinib 8.5
Vatalanib 8.3
Midostaurin 8.3
Motesanib 7.8
Bisacodyl 7.8
Axitinib 7.8
IL-11 7.2
EML 7.1
Dasatinib 6.7
Nexavar 6.5
Beraprost 6.5
Zaditen 6.4
Methylcellulose 6.4
Beraprost sodium 6.2
Sorafenib 6.1
Sunitinib malate 6.1
G-CSF 5.9
TEL 5.8
Tarceva 5.5
Gastro 5.4
Ipilimumab 5.2
Trabectedin 5.1
Rosuvastatin 5.0
Sonazoid 4.9
anti-CD33 4.8
Peridex 4.8
CSF 4.8
Erlotinib 4.7
SMP 4.7
Lupron 4.6
Tranilast 4.6
Olmesartan 4.5
NOV 4.5
LCM 4.5
LCM 4.5
Giardiasis 4.4
Miltefosine 4.3
KGF 4.3
p75 4.3
AIC 4.2
ETS 4.2
MDS 4.1
Herceptin 4.1
Ketotifen 4.1
Mirtazapine 4.0
Cetuximab 3.9
PDL 3.9
Codeine 3.8
Bevacizumab 3.8
Paraffin 3.7
Codeine 3.7
Retinoic Acid 3.7
CTT 3.6
MDM 3.5
Aminoguanidine 3.5
Activin 3.5
G418 3.4
CAM 3.4
Fludarabine 3.4
Emodin 3.4
MTC 3.3
uPA 3.2
TAC 3.2
Emodin 3.1
Gefitinib 3.0
Taxotere 3.0
CoCl2 3.0
CoCl2 3.0
Glide 2.9
Lenalidomide 2.9
Itraconazole 2.9
Isotretinoin 2.9
IL-2 2.7
Bortezomib 2.7
TAT 2.6
Pravastatin 2.6
more...
Enzyme
tryptase 8.0
chymase 7.6
Thy1 7.3
alpha-methylacyl-CoA racemase 7.0
LTC4 synthase 6.3
CD13 5.5
ERK 5.4
TdT 5.4
glycoprotease 5.3
DCF 5.1
AMPK 5.1
histidine decarboxylase 5.0
carboxypeptidase A 4.9
caspase-10 4.8
focal adhesion kinase 4.7
caspase-10 4.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.6
CD10 4.5
thyroid peroxidase 4.4
exonuclease I 4.4
inositol 3-kinase 4.4
caspase-6 4.3
iduronate-2-sulfatase 4.3
TSA 4.3
cytosine deaminase 4.3
caspase-6 4.3
hexosaminidase 4.3
tyrosine aminotransferase 4.2
cathepsin K 4.2
TACE 4.2
phosphatidylinositol 3-kinase 4.2
biliverdin reductase 4.1
fumarylacetoacetate hydrolase 4.1
HPI 4.0
enolase 4.0
Rex 4.0
tyrosinase 4.0
granzyme B 3.9
acrosin 3.8
trypsin 3.8
SMP 3.8
TOR 3.7
CEP 3.7
legumain 3.6
GLO 3.6
chymopapain 3.6
HCS 3.6
dipeptidyl peptidase IV 3.5
phosphoinositide 3-kinase 3.5
NOS 3.5
chymopapain 3.5
tryptophan 2,3-dioxygenase 3.5
MEK 3.5
choline kinase 3.5
PDK1 3.4
p100 3.4
SCP 3.4
AMP-activated kinase 3.4
STK11 3.4
uroporphyrinogen decarboxylase 3.4
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
plasmin 3.3
PTPase 3.3
TGT 3.2
farnesyltransferase 3.2
CNPase 3.2
phosphoglycerate kinase 3.2
matrix metalloproteinase 9 3.1
CEP 3.1
reverse transcriptase 3.1
CDH 3.1
aldehyde dehydrogenase 3.1
aldehyde dehydrogenase 3.0
MTD 3.0
mitogen-activated protein kinase 3.0
NAT 2.9
neutral sphingomyelinase 2.9
transcriptase 2.8
more...
Compound
Nevadensin 9.9
W37 8.7
2,4-pyrimidinediamine 8.5
Neomycin sulfate 8.0
Neomycin sulfate 7.8
Hymenialdisine 7.6
ONB 7.4
2,4-dihydroxybenzaldehyde 7.3
Nickel sulfate 7.2
Janus Green B 7.2
2,4-dihydroxybenzaldehyde 7.2
2,4-dihydroxybenzaldehyde 7.2
TKB 6.8
Theaflavin 6.8
Allethrin 6.7
Aloin 6.7
Oxindole 6.7
Ginsenoside Re 6.5
dUDP 6.4
DMP 6.3
Aloin 6.3
DMP 6.3
DX-52-1 6.3
DMP 6.3
CD 3 6.2
Geniposide 6.0
Temsirolimus 5.9
CMK 5.9
Cromolyn 5.9
A 99 5.8
Cbl 5.8
Toluidine blue 5.8
TEL 5.8
Deoxyspergualin 5.7
Guanidinoacetic acid 5.7
Homoharringtonine 5.7
ABL 5.7
ED 20 5.7
Latrunculin B 5.6
GC-1 5.5
LTC4 5.5
BCR 5.5
Oil Red 5.5
HPC 5.5
Reticulin 5.5
NIX 5.5
DHM 5.4
3-methylpyridine 5.4
HPC 5.4
SDZ PSC 833 5.4
Polybrene 5.4
HMBA 5.3
NFS 5.3
S-allylcysteine 5.2
A 150 5.2
Evodiamine 5.2
Rhodamine 123 5.1
VLA 5.1
HPP 5.1
Evodiamine 5.1
Florid 5.1
2-hydroxybenzaldehyde 5.0
Esculetin 5.0
Benzidine 5.0
SHS 5.0
phthalazine 5.0
Hoechst 33342 5.0
Tyrosine 5.0
DMP 4.9
HMBA 4.9
Wortmannin 4.9
methoxyacetic acid 4.8
DAPT 4.8
Nobiletin 4.7
Hematoxylin 4.7
tyrosine 4.7
BAL 4.6
Sudan IV 4.6
K19 4.6
MGA 4.6
more...