Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P10721 (c-kit)
6,575 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein c-kit 6575 stem cell factor 1127 CD34 821 tyrosine kinase 671 CD117 541 mast cell 538 Sep 447 cytokine 422 Mol 403 receptor tyrosine kinase 390 KIT 321 proto-oncogene 313 erythroid 302 lymphoid 290 IL-3 255 CD45 253 SCF 232 mast cell growth factor 225 kit 225 vimentin 218 tyrosine kinase receptor 210 platelet-derived growth factor receptor 196 desmin 165 IL-6 163 granulocyte 155 p53 147 erythropoietin 139 PDGFR 137 GM-CSF 135 smooth muscle actin 133 CD4 130 gut 123 granulocyte-macrophage colony-stimulating factor 114 vascular endothelial growth factor 113 macrophage colony-stimulating factor 111 CD31 110 thymus 107 VEGFR2 106 collagen 104 IgE 100 VEGF 98 PDGF 97 IL-7 96 platelet-derived growth factor 95 Ki-67 92 Thy-1 90 CD44 90 IL-4 89 CD8 86 c-fms 84 S100 83 CSF 82 granulocyte colony-stimulating factor 81 SMA 80 CXCR4 79 PDGFRA 78 epidermal growth factor receptor 78 p56lck 78 CD11b 77 granulocyte-macrophage 76 thrombopoietin 75 EGFR 75 FLT3 73 insulin 72 megakaryocyte 72 CD133 72 cytokeratin 71 membrane-bound 71 CD25 71 vascular endothelial growth factor receptor 69 G-CSF 65 Bcl-2 65 BRAF 64 bcl-2 64 ABL 63 AKT 63 TNF 62 BCR 61 alpha-smooth muscle actin 58 hematopoietic stem and progenitor cells 57 more...

Disease tumor 1148 cancer 826 gastrointestinal stromal tumor 381 stromal tumors 371 leukemia 298 acute myeloid leukemia 263 mastocytosis 212 chronic myeloid leukemia 178 melanoma 164 carcinoma 155 metastases 155 tumorigenesis 108 myocardial infarction 106 anemia 106 sarcoma 97 tumor growth 90 lymphoma 89 breast cancer 79 myelodysplastic syndrome 67 Leukemia 66 renal cell carcinoma 66 heart failure 65 mastocytoma 64 ABL 63 diabetes 59 adenocarcinoma 56 uterus 55 asthma 50 ischemia 48 ICC 47 ICC 47 leukemogenesis 47 SCID 46 carcinogenesis 45 myeloproliferative disorders 45 hepatocellular carcinoma 44 tumor progression 44 lung cancer 43 acute lymphoblastic leukemia 40 leiomyoma 38 Mastocytosis 37 hypertension 37 leiomyosarcoma 37 seminoma 37 primary tumor 36 Melanoma 34 metastatic melanoma 34 acute leukemia 33 liver metastases 32 small cell lung cancer 31 myeloid leukemia 30 colorectal cancer 30 mast cell leukemia 29 tumor angiogenesis 29 neuroblastoma 29 squamous cell carcinoma 29 multiple myeloma 28 schwannoma 26 lung carcinoma 26 WT1 26 neurofibromatosis type 1 25 hematologic malignancies 25 solid tumor 25 ovarian cancer 25 infertility 24 glioma 23 urticaria pigmentosa 23 erythroleukemia 23 eosinophilia 23 NOD 23 non-small cell lung cancer 23 glioblastoma 22 prostate cancer 22 thrombocytopenia 22 gastric cancer 22 Systemic mastocytosis 21 myelosuppression 21 PBT 21 anaphylaxis 21 rare disease 20 more...

Symptom abdominal pain 53 diarrhea 32 constipation 31 fatigue 25 pain 21 splenomegaly 19 functional recovery 18 nausea 16 vomiting 15 anorexia 13 exhaustion 11 weakness 10 dyspnea 9 HSA 9 headache 9 Spotting 8 flushing 7 starvation 7 anesthesia 7 discomfort 6 hepatosplenomegaly 6 discomfort 6 back pain 6 syncope 6 dizziness 5 collapse 5 thinning 5 respiratory distress 5 hepatomegaly 4 pelvic pain 4 bone pain 4 lethargy 4 acute abdominal pain 3 Darier's sign 3 chest pain 3 abdominal discomfort 3 epigastric pain 3 seizures 3 cough 3 flank pain 3 hyperoxia 3 skin irritation 2 decreased appetite 2 dysuria 2 hip pain 2 asthenia 2 colic 2 ataxia 2 nausea and vomiting 2 numbness 2 chronic constipation 2 Welt 2 acute abdomen 2 periorbital edema 2 hoarseness 2 bloating 2 tenesmus 2 urinary frequency 2 dry eye 1 shortness of breath 1 DNA marker 1 acute stress 1 sleepiness 1 acidity 1 cerebellar ataxia 1 female puberty 1 dyschezia 1 regurgitation 1 memory loss 1 tense 1 acute pain 1 paresthesia 1 emaciation 1 chills 1 lightheadedness 1 polydipsia 1 myalgia 1 leg edema 1 abdominal fullness 1 ophthalmoplegia 1 more...

Drug Imatinib 255 Gleevec 198 CSF 179 Dermatol 116 G-CSF 65 IL-2 40 IL-11 35 IFN-gamma 25 Sorafenib 22 p75 16 Cardiovasc 13 CAM 13 Dasatinib 13 lysine 13 Asn 11 CTX 11 caffeine 10 ETS 10 TEL 9 MAP 9 Leaf 9 Asthma 8 MDS 8 Gastro 8 Herceptin 8 ABC 7 Histamine 6 Axitinib 6 Paraffin 6 Gel 6 G418 5 Bevacizumab 5 EML 5 Activin 4 uPA 4 Midostaurin 4 Monit 4 Erlotinib 4 ROC 3 TAC 3 ROS 3 Cetuximab 3 Atropine 3 Rosuvastatin 3 CTX 3 Portal 3 Bisacodyl 3 DNase I 3 TAT 3 CTX 3 Adriamycin 3 Ipilimumab 3 Angiotensin II 3 Vatalanib 3 Itraconazole 3 Retinoic acid 2 Taxol 2 PTH 2 ICI 2 Tandutinib 2 Nephron 2 Methylcellulose 2 LCM 2 KGF 2 PTC 2 Tarceva 2 AIC 2 Simvastatin 2 Ethanol 2 Sunitinib malate 2 Fructose 2 PDL 2 Gefitinib 2 Albumin 2 LCM 2 Nexavar 2 Mutagen 2 Fluorescein 2 ascorbate 2 SMP 2 more...

Enzyme ERK 832 focal adhesion kinase 244 mitogen-activated protein kinase 159 tryptase 147 trypsin 123 protein kinase 76 protein kinase C 57 reverse transcriptase 56 chymase 55 peroxidase 46 CD10 46 AMPK 44 MEK 42 phosphatidylinositol 3-kinase 41 Thy1 40 alkaline phosphatase 37 caspase-3 35 CD13 34 tyrosinase 29 luciferase 22 RNase 18 plasmin 18 phospholipase C 17 RNA polymerase 17 RNase 17 NOS 17 TdT 16 APC 15 transcriptase 14 phosphoinositide 3-kinase 14 thyroid peroxidase 14 hexosaminidase 14 DCF 14 acetylcholinesterase 13 thrombin 13 glutathione S-transferase 13 NO synthase 12 proteasome 12 catalase 12 enolase 12 P-glycoprotein 12 PARP 11 aldehyde dehydrogenase 11 beta-galactosidase 10 histidine decarboxylase 10 ACS 10 ATPase 10 granzyme B 10 aldehyde dehydrogenase 9 tyrosine hydroxylase 9 collagenase 9 MAP 9 aldehyde dehydrogenase 9 aldehyde dehydrogenase 9 aldehyde dehydrogenase 9 GSK 8 succinate dehydrogenase 8 lactate dehydrogenase 8 superoxide dismutase 8 cathepsin K 7 aspartate aminotransferase 7 renin 7 adenylate cyclase 6 MIP 6 lysozyme 6 cdc2 6 carboxypeptidase A 6 NADPH oxidase 6 phospholipase A2 6 urokinase-type plasminogen activator 6 tissue plasminogen activator 6 PDK1 5 caspase-8 5 topoisomerase 5 tyrosine aminotransferase 5 TSA 5 calcineurin 5 topoisomerase 5 choline acetyltransferase 5 elastase 5 more...

Compound tyrosine 517 Dec 485 DNA 387 Clin 224 calcium 87 oxygen 81 ABL 63 TNF 62 BCR 61 retinoic acid 51 ATP 51 Asp 49 serine 46 glucose 45 nitric oxide 41 acetate 40 threonine 38 MEK 38 Cardiol 33 water 33 sodium 32 methionine 27 LTC4 27 lysine 26 arginine 26 Tyrosine 25 phosphate 24 MTT 23 Cbl 21 Phe 20 sulfate 20 Gly 19 iodine 17 His 17 formaldehyde 16 tryptophan 16 hydrogen 16 leucine 16 zinc 15 Hoechst 33342 15 urea 15 BAL 14 aspartic acid 14 CAM 14 potassium 14 cAMP 14 silver 14 Hematoxylin 14 aspartic acid 13 COS 13 aspartic acid 13 aspartic acid 13 DMP 12 DMP 12 DMP 12 alanine 12 cysteine 12 DMP 12 dUTP 11 CTX 11 bromide 11 HPP 10 pyrimidine 10 pyrimidine 10 caffeine 10 ACS 10 ACS 10 valine 9 Ara-C 9 PMA 9 MAP 9 iron 9 acridine 9 TEL 9 barium 8 PGD2 8 DMSO 8 salt 8 A 71 8 ethanol 8 more...

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