Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UNIPROT:P10721 (c-kit)
6,575 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein c-kit 6575 stem cell factor 1127 CD34 821 tyrosine kinase 671 CD117 541 mast cell 538 Sep 447 cytokine 422 Mol 403 receptor tyrosine kinase 390 KIT 321 proto-oncogene 313 erythroid 302 lymphoid 290 IL-3 255 CD45 253 SCF 232 kit 225 mast cell growth factor 225 vimentin 218 tyrosine kinase receptor 210 platelet-derived growth factor receptor 196 desmin 165 IL-6 163 granulocyte 155 p53 147 erythropoietin 139 PDGFR 137 GM-CSF 135 smooth muscle actin 133 CD4 130 gut 123 granulocyte-macrophage colony-stimulating factor 114 vascular endothelial growth factor 113 macrophage colony-stimulating factor 111 CD31 110 thymus 107 VEGFR2 106 collagen 104 IgE 100 more...

Disease tumor 1148 cancer 826 gastrointestinal stromal tumor 381 stromal tumors 371 leukemia 298 acute myeloid leukemia 263 mastocytosis 212 chronic myeloid leukemia 178 melanoma 164 metastases 155 carcinoma 155 tumorigenesis 108 myocardial infarction 106 anemia 106 sarcoma 97 tumor growth 90 lymphoma 89 breast cancer 79 myelodysplastic syndrome 67 Leukemia 66 renal cell carcinoma 66 heart failure 65 mastocytoma 64 ABL 63 diabetes 59 adenocarcinoma 56 uterus 55 asthma 50 ischemia 48 leukemogenesis 47 ICC 47 ICC 47 SCID 46 myeloproliferative disorders 45 carcinogenesis 45 tumor progression 44 hepatocellular carcinoma 44 lung cancer 43 acute lymphoblastic leukemia 40 leiomyoma 38 more...

Symptom abdominal pain 53 diarrhea 32 constipation 31 fatigue 25 pain 21 splenomegaly 19 functional recovery 18 nausea 16 vomiting 15 anorexia 13 exhaustion 11 weakness 10 dyspnea 9 headache 9 HSA 9 Spotting 8 starvation 7 flushing 7 anesthesia 7 discomfort 6 discomfort 6 hepatosplenomegaly 6 syncope 6 back pain 6 collapse 5 thinning 5 dizziness 5 respiratory distress 5 pelvic pain 4 hepatomegaly 4 bone pain 4 lethargy 4 flank pain 3 Darier's sign 3 epigastric pain 3 acute abdominal pain 3 hyperoxia 3 cough 3 chest pain 3 abdominal discomfort 3 more...

Drug Imatinib 255 Gleevec 198 CSF 179 Dermatol 116 G-CSF 65 IL-2 40 IL-11 35 IFN-gamma 25 Sorafenib 22 p75 16 Cardiovasc 13 CAM 13 lysine 13 Dasatinib 13 Asn 11 CTX 11 ETS 10 caffeine 10 TEL 9 MAP 9 Leaf 9 Asthma 8 MDS 8 Gastro 8 Herceptin 8 ABC 7 Paraffin 6 Gel 6 Axitinib 6 Histamine 6 G418 5 EML 5 Bevacizumab 5 Erlotinib 4 Activin 4 Midostaurin 4 Monit 4 uPA 4 ROC 3 CTX 3 more...

Enzyme ERK 832 focal adhesion kinase 244 mitogen-activated protein kinase 159 tryptase 147 trypsin 123 protein kinase 76 protein kinase C 57 reverse transcriptase 56 chymase 55 CD10 46 peroxidase 46 AMPK 44 MEK 42 phosphatidylinositol 3-kinase 41 Thy1 40 alkaline phosphatase 37 caspase-3 35 CD13 34 tyrosinase 29 luciferase 22 plasmin 18 RNase 18 RNase 17 RNA polymerase 17 NOS 17 phospholipase C 17 TdT 16 APC 15 transcriptase 14 phosphoinositide 3-kinase 14 DCF 14 hexosaminidase 14 thyroid peroxidase 14 glutathione S-transferase 13 acetylcholinesterase 13 thrombin 13 proteasome 12 NO synthase 12 enolase 12 catalase 12 more...

Compound tyrosine 517 Dec 485 DNA 387 Clin 224 calcium 87 oxygen 81 ABL 63 TNF 62 BCR 61 retinoic acid 51 ATP 51 Asp 49 serine 46 glucose 45 nitric oxide 41 acetate 40 threonine 38 MEK 38 Cardiol 33 water 33 sodium 32 LTC4 27 methionine 27 lysine 26 arginine 26 Tyrosine 25 phosphate 24 MTT 23 Cbl 21 sulfate 20 Phe 20 Gly 19 iodine 17 His 17 formaldehyde 16 hydrogen 16 tryptophan 16 leucine 16 Hoechst 33342 15 zinc 15 more...

---