Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10721 (c-kit)
 6,575 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
c-kit 6575
stem cell factor 1127
CD34 821
tyrosine kinase 671
CD117 541
mast cell 538
Sep 447
cytokine 422
Mol 403
receptor tyrosine kinase 390
KIT 321
proto-oncogene 313
erythroid 302
lymphoid 290
IL-3 255
CD45 253
SCF 232
mast cell growth factor 225
kit 225
vimentin 218
more...
Disease
tumor 1148
cancer 826
gastrointestinal stromal tumor 381
stromal tumors 371
leukemia 298
acute myeloid leukemia 263
mastocytosis 212
chronic myeloid leukemia 178
melanoma 164
metastases 155
carcinoma 155
tumorigenesis 108
myocardial infarction 106
anemia 106
sarcoma 97
tumor growth 90
lymphoma 89
breast cancer 79
myelodysplastic syndrome 67
renal cell carcinoma 66
more...
Symptom
abdominal pain 53
diarrhea 32
constipation 31
fatigue 25
pain 21
splenomegaly 19
functional recovery 18
nausea 16
vomiting 15
anorexia 13
exhaustion 11
weakness 10
headache 9
dyspnea 9
HSA 9
Spotting 8
flushing 7
starvation 7
anesthesia 7
discomfort 6
more...
Drug
Imatinib 255
Gleevec 198
CSF 179
Dermatol 116
G-CSF 65
IL-2 40
IL-11 35
IFN-gamma 25
Sorafenib 22
p75 16
lysine 13
Cardiovasc 13
CAM 13
Dasatinib 13
CTX 11
Asn 11
caffeine 10
ETS 10
TEL 9
MAP 9
more...
Enzyme
ERK 832
focal adhesion kinase 244
mitogen-activated protein kinase 159
tryptase 147
trypsin 123
protein kinase 76
protein kinase C 57
reverse transcriptase 56
chymase 55
peroxidase 46
CD10 46
AMPK 44
MEK 42
phosphatidylinositol 3-kinase 41
Thy1 40
alkaline phosphatase 37
caspase-3 35
CD13 34
tyrosinase 29
luciferase 22
more...
Compound
tyrosine 517
Dec 485
DNA 387
Clin 224
calcium 87
oxygen 81
ABL 63
TNF 62
BCR 61
ATP 51
retinoic acid 51
Asp 49
serine 46
glucose 45
nitric oxide 41
acetate 40
MEK 38
threonine 38
Cardiol 33
water 33
more...