Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10721 (c-kit)
 6,575 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
c-kit 12.2
Mast cell growth factor 11.7
TFG-NR4A3 fusion 11.2
exosome component 10 11.2
H-RAS protein 11.2
Receptor protein tyrosine kinase 11.2
stem cell factor, SCF 11.2
HBEX2 11.2
alpha-methyl-acyl-CoA racemase 11.2
H2B-GL105 11.2
ELKL motif kinase 11.2
Src-like-adaptor 11.2
zinc finger protein 16 11.2
kit-ligand 10.7
apoptosis repressor with CARD domain 10.7
casein kinase-1 binding protein 10.7
EDRF1 10.7
MITF-C 10.7
stem cell tyrosine kinase 1 10.7
mast cell growth factor 10.5
stem cell factor 10.4
ZNF16 10.2
G protein-coupled receptor 125 10.2
ABCC10 protein 10.2
FLT2 10.2
hematopoietic stem cell antigen 10.2
KIT protein 10.2
stem cell growth factor 10.0
GAGE-7 9.9
HSD17 9.9
CD117 9.8
inhibin, alpha 9.7
chromobox homolog 8 9.7
NAK-associated protein 1 9.7
PRDM7 9.7
HZF1 9.7
fms-related tyrosine kinase 3 9.6
SR-1 9.5
GDF-3 9.4
HMG20B 9.4
MAGEB4 9.4
SAMD14 9.4
transcription factor Pax-5 9.2
STK-1 9.2
PH domain and leucine rich repeat protein phosphatase 9.2
Spred-3 9.2
CRIP2 9.2
YBX1 protein 9.2
MGF 9.1
neurobeachin-like 2 9.1
claudin 8 9.1
TPSB2 9.1
ORP10 9.1
CALM/AF10 fusion 9.1
POU domain class 5 transcription factor 1 9.1
BRDG1 9.1
EPC-like 9.1
STK1 9.0
platelet-derived growth factor receptor 8.9
Tyrosinase-related protein-2 8.9
POPDC2 8.9
MRD2 8.9
GIST 8.9
platelet-derived growth factor receptor alpha 8.9
placental-like alkaline phosphatase 8.9
CD150 8.9
MPP3 8.8
tyrosine kinase receptor 8.8
PDGFR 8.8
Flt3 ligand 8.8
ORP4 8.8
TAF4B 8.8
RNA-binding motif protein 15 8.8
SPINLW1 8.8
Spred-1 8.8
microphtalmia-associated transcription factor 8.8
edg-2 8.8
podocalyxin-like protein 8.7
Sal-like protein 4 8.7
focal adhesion kinase 1 8.7
MEK kinase 2 8.7
BCR/ABL fusion protein 8.6
KIT 8.6
IL17RC 8.5
eppin 8.5
Spred-2 8.5
RDC-1 8.5
Grap 8.5
KITLG 8.5
flt 8.4
RNF41 8.4
MIHC 8.4
Annexin A8 8.4
PSF3 8.4
SLD5 8.4
CD34 molecule 8.4
FcERI 8.4
bone marrow stromal cell antigen 1 8.4
tal-1 8.4
dedicator of cytokinesis 2 8.4
ACK 8.4
TYRP2 8.4
H-PGDS 8.3
POPDC1 8.3
PDGFRA 8.3
P145 8.3
SCF 8.3
mast cell tryptase 8.3
PSG5 8.2
CLP-1 8.2
STRA8 8.2
Interleukin-25 8.2
MLCK protein 8.2
tesmin 8.2
transmembrane protein 16A 8.2
mast cell protease II 8.2
MOK 8.2
Fms-related tyrosine kinase 3 8.2
endoglycan 8.2
Spi-B 8.1
CD34 antigen 8.1
PGLYRP 8.1
SERPINB6 8.1
GJC1 8.1
cell death activator 8.1
RAB5B 8.1
CD48 8.0
VASA 8.0
CD130 8.0
TLS-ERG 8.0
HIG2 8.0
CPA3 8.0
Int3 8.0
GATA-2 8.0
PSF2 7.9
defender against cell death 1 7.9
Lysocardiolipin acyltransferase 7.9
Mp1 7.9
FLT3L 7.9
leukocyte tyrosine kinase 7.9
CD34 7.9
CD41 7.9
SCP3 7.9
Endomucin 7.8
ETV2 7.8
PLAP 7.8
AFAR 7.8
Prostaglandin D2 synthase 7.8
p56lck 7.8
Enh 7.8
SPINK2 7.8
OPLA 7.8
Interleukin-3 7.8
Receptor tyrosine kinase 7.8
Hepatocyte growth factor receptor 7.7
HDC protein 7.7
TPL-2 7.7
PSF1 7.7
F11R 7.7
PDS5 7.7
more...
Disease
Reactive mastocytosis 12.2
Postmenopausal disorders 12.2
adult brainstem glioma 11.2
Thymic epithelial neoplasm 11.2
Diabetic gastroenteropathy 11.2
Gastrointestinal stromal sarcoma 10.9
Spindle cell melanoma 10.8
Familial mastocytosis 10.7
Cutaneous mastocytosis 10.5
SM-AHNMD 10.4
Telangiectasia macularis eruptiva perstans 10.4
LFSS 10.2
HPC3 10.2
mast cell leukemia 9.7
untreated adult AML 9.7
Diffuse cutaneous mastocytosis 9.5
type B thymoma 9.4
CSPC 9.4
CMML-2 9.4
ECA3 9.2
gastrointestinal stromal tumor 9.2
Mastocytosis 9.2
stromal tumors 9.0
CNS germinoma 9.0
megasigmoid 8.9
mastocytosis 8.9
Adenoid basal carcinoma 8.8
Systemic mastocytosis 8.7
skin pigmentation disorder 8.5
Inflammatory fibroid polyp 8.5
Acute basophilic leukemia 8.4
CIIP 8.4
childhood ependymoma 8.4
trisomy 12q 8.3
neoplasm of uncertain malignant potential 8.3
urticaria pigmentosa 8.3
Undifferentiated sarcoma 8.2
Vitiligo vulgaris 8.2
Plexiform schwannoma 8.2
Infantile malignant osteopetrosis 8.1
Total colonic aganglionosis 8.1
Malignant granular cell tumor 7.9
Staphylococcus aureus abscess 7.9
CASTLE 7.9
refractory testicular cancer 7.8
PBT 7.6
Mesenteric fibromatosis 7.5
mastocytoma 7.5
Bile duct cancer 7.4
Leukemia stem cell 7.4
Mesoblastic nephroma 7.4
CASTLE 7.4
Chloroma 7.3
Gastric lymphoma 7.3
Landau-Kleffner syndrome 7.3
congenital anemia 7.2
hepatocholangiocarcinoma 7.2
plexiform schwannoma 7.1
gallbladder empyema 7.1
FPD/AML 7.1
Gastrointestinal Tumor 7.1
Spermatocytic seminoma 7.1
invasive lobular breast carcinoma 7.0
Riehl's melanosis 7.0
cHL 6.9
Adenomyoepithelioma 6.9
Adenomyoepithelioma 6.9
chronic eosinophilic leukemia 6.9
macrocytic anemia 6.9
Metastatic malignant melanoma 6.8
Diabetic gastroparesis 6.8
epithelial thymoma 6.8
thymic carcinoma 6.8
ICC 6.6
preneoplastic state 6.6
MDS/MPD 6.6
ICC 6.6
poliosis 6.6
congenital hypoplastic anemia 6.5
benign ovarian cyst 6.5
muscle neoplasm 6.5
Adenoid cystic carcinoma 6.5
Mooren's ulcer 6.5
FDC 6.5
Hunner 6.5
small cell carcinoma of the cervix 6.5
HPP 6.4
Eosinophilic cystitis 6.4
Hemangioblastoma 6.4
Intestinal pseudo-obstruction 6.4
TGCT 6.4
HPP 6.4
dysgerminoma 6.3
uterine neoplasm 6.3
ovarian sarcoma 6.3
HPC1 6.2
Lipomatous hypertrophy 6.2
Dedifferentiated liposarcoma 6.2
Myxoid liposarcoma 6.2
LAD2 6.2
Renal interstitial fibrosis 6.1
Pseudolymphoma 6.1
bone marrow disorder 6.1
ABL 6.1
Lymphocytic infiltration 6.0
Mixed cellularity 6.0
Sclerosing mesenteritis 6.0
Testes 6.0
seminoma 5.9
fibromyxoma 5.9
chronic myelomonocytic leukemia 5.9
FAB M2 5.9
Undifferentiated carcinoma 5.9
hand-foot syndrome 5.9
EVR 5.8
FAB M1 5.8
leukoderma 5.8
compound nevus 5.8
AA1 5.8
germinoma 5.8
leukemogenesis 5.8
blepharophimosis-ptosis-epicanthus inversus syndrome 5.8
iris melanoma 5.8
PEComa 5.8
rectal polyp 5.7
dermatofibrosarcoma protuberans 5.7
megakaryocytic leukemia 5.7
Atypical fibroxanthoma 5.7
spindle cell thymoma 5.6
PNET 5.6
somatostatinoma 5.6
testicular dysfunction 5.6
SACS 5.6
Primary leiomyosarcoma 5.6
pediatric AML 5.6
acute undifferentiated leukemia 5.5
plexiform neurofibroma 5.5
intradermal nevus 5.5
Escherichia coli bacteremia 5.5
chronic myeloid leukemia 5.5
adult AML 5.5
endocrine neoplasm 5.4
myeloproliferative disorders 5.4
Endometrium 5.4
chloroma 5.4
Endometrium 5.4
pediatric medulloblastoma 5.4
WS1 5.4
Cardiac myxoma 5.4
AML progression 5.4
HPC 5.4
Giardia infections 5.4
hypermethioninemia 5.4
Waardenburg syndrome 5.3
PNET 5.3
phyllodes tumor 5.3
HRD 5.3
adenocarcinoma of the gallbladder 5.3
Cornelia de Lange 5.3
Carcinosarcoma 5.3
more...
Symptom
Spotting 8.8
Darier's sign 8.2
female puberty 5.3
periorbital edema 5.3
dyschezia 4.4
tenesmus 4.3
anal pain 4.3
male subfertility 4.2
constipation 3.9
HSA 3.9
abdominal fullness 3.6
stomach pain 3.3
lightheadedness 3.2
splenomegaly 3.2
urinary frequency 3.1
abdominal discomfort 3.1
decreased appetite 3.0
abdominal pain 3.0
chronic constipation 2.9
acute abdominal pain 2.9
leg edema 2.8
flank pain 2.7
hepatosplenomegaly 2.7
functional recovery 2.7
bone pain 2.6
intestinal bleeding 2.6
consciousness disturbance 2.6
bloating 2.5
hip pain 2.4
flushing 2.4
DNA marker 2.4
pelvic pain 2.3
emaciation 2.2
anorexia 2.2
skin irritation 2.2
epigastric pain 2.1
dysuria 2.0
exhaustion 2.0
asthenia 1.9
nasal discharge 1.8
lethargy 1.8
hepatomegaly 1.7
nausea 1.7
hoarseness 1.7
acute abdomen 1.7
syncope 1.7
colic 1.6
hyperoxia 1.5
diarrhea 1.4
dizziness 1.3
back pain 1.3
fatigue 1.2
fever of unknown origin 1.2
vomiting 1.2
tense 1.2
polydipsia 1.1
thinning 1.1
numbness 0.9
dry eye 0.9
shoulder pain 0.8
polyuria 0.7
dyspnea 0.6
ophthalmoplegia 0.5
starvation 0.4
cerebellar ataxia 0.4
memory loss 0.4
discomfort 0.4
cyanosis 0.4
weakness 0.4
respiratory distress 0.3
acute pain 0.3
discomfort 0.2
chills 0.2
acute stress 0.1
nausea and vomiting 0.0
paresthesia -0.0
shortness of breath -0.1
collapse -0.2
chest pain -0.2
headache -0.4
myalgia -0.4
ataxia -0.7
cough -0.7
Welt -0.7
regurgitation -0.8
low back pain -1.0
pain -1.4
sleepiness -1.4
erythema -1.4
acidity -1.6
anesthesia -1.7
seizures -2.5
Drug
Tandutinib 10.4
Gleevec 9.4
Imatinib 9.0
Hymenialdisine 8.9
Lestaurtinib 8.5
Vatalanib 8.3
Midostaurin 8.3
Motesanib 7.8
Bisacodyl 7.8
Axitinib 7.8
IL-11 7.2
EML 7.1
Dasatinib 6.7
Nexavar 6.5
Beraprost 6.5
Zaditen 6.4
Methylcellulose 6.4
Beraprost sodium 6.2
Sorafenib 6.1
Sunitinib malate 6.1
G-CSF 5.9
TEL 5.8
Tarceva 5.5
Gastro 5.4
Ipilimumab 5.2
Trabectedin 5.1
Rosuvastatin 5.0
Sonazoid 4.9
anti-CD33 4.8
Peridex 4.8
CSF 4.8
Erlotinib 4.7
SMP 4.7
Lupron 4.6
Tranilast 4.6
Olmesartan 4.5
NOV 4.5
LCM 4.5
LCM 4.5
Giardiasis 4.4
Miltefosine 4.3
KGF 4.3
p75 4.3
AIC 4.2
ETS 4.2
MDS 4.1
Herceptin 4.1
Ketotifen 4.1
Mirtazapine 4.0
Cetuximab 3.9
PDL 3.9
Codeine 3.8
Bevacizumab 3.8
Paraffin 3.7
Codeine 3.7
Retinoic Acid 3.7
CTT 3.6
MDM 3.5
Aminoguanidine 3.5
Activin 3.5
G418 3.4
CAM 3.4
Fludarabine 3.4
Emodin 3.4
MTC 3.3
uPA 3.2
TAC 3.2
Emodin 3.1
Gefitinib 3.0
Taxotere 3.0
CoCl2 3.0
CoCl2 3.0
Glide 2.9
Lenalidomide 2.9
Itraconazole 2.9
Isotretinoin 2.9
IL-2 2.7
Bortezomib 2.7
TAT 2.6
Pravastatin 2.6
Irinotecan 2.6
Simvastatin 2.5
PTC 2.5
CTX 2.4
Histamine 2.4
Fructose 2.3
NVP 2.3
Sodium nitroprusside 2.3
TAK 2.3
Reserpine 2.3
Prednisone 2.3
CTC 2.2
Asn 2.2
Doxycycline 2.2
Atropine 2.1
DMAP 2.1
Etoposide 2.1
IFN-gamma 2.1
Phentolamine 2.0
RFP 2.0
ABC 1.9
Methylene blue 1.9
CTC 1.9
CCL 1.9
Portal 1.8
CTA 1.8
Prednisolone 1.7
balanced salt solution 1.7
Allergen 1.6
Adriamycin 1.6
DM1 1.6
Ranitidine 1.6
Taxol 1.6
Angiotensin II 1.5
Retinoic acid 1.5
MAP 1.5
Norplant 1.5
Docetaxel 1.5
TTC 1.4
Fluorescein 1.4
CTX 1.4
CPT-11 1.4
CTX 1.3
-deoxyadenosine 1.2
caffeine 1.2
Dermatol 1.1
Captopril 1.1
Fragment 1.1
Albumin 1.0
Leaf 1.0
Gel 1.0
Fraction 0.9
ROC 0.9
Nitric Oxide 0.9
HCG 0.9
ICI 0.8
DNase I 0.8
ETA 0.8
Alanine 0.8
Mutagen 0.7
IFN-beta 0.7
Heme 0.6
Asthma 0.6
PTH 0.5
PCB 0.2
lysine 0.1
Ethanol -0.0
ROS -0.4
EE2 -0.7
ENT -0.8
Monit -0.9
nitroglycerin -0.9
Nephron -0.9
ascorbate -1.3
ZnO -1.5
Cardiovasc -1.7
lactose -1.8
NADH -2.2
Enzyme
tryptase 8.0
chymase 7.6
Thy1 7.3
alpha-methylacyl-CoA racemase 7.0
LTC4 synthase 6.3
CD13 5.5
ERK 5.4
TdT 5.4
glycoprotease 5.3
DCF 5.1
AMPK 5.1
histidine decarboxylase 5.0
carboxypeptidase A 4.9
caspase-10 4.8
focal adhesion kinase 4.7
caspase-10 4.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.6
CD10 4.5
thyroid peroxidase 4.4
exonuclease I 4.4
inositol 3-kinase 4.4
caspase-6 4.3
iduronate-2-sulfatase 4.3
TSA 4.3
cytosine deaminase 4.3
caspase-6 4.3
hexosaminidase 4.3
tyrosine aminotransferase 4.2
cathepsin K 4.2
TACE 4.2
phosphatidylinositol 3-kinase 4.2
biliverdin reductase 4.1
fumarylacetoacetate hydrolase 4.1
HPI 4.0
enolase 4.0
Rex 4.0
tyrosinase 4.0
granzyme B 3.9
acrosin 3.8
trypsin 3.8
SMP 3.8
TOR 3.7
CEP 3.7
legumain 3.6
GLO 3.6
chymopapain 3.6
HCS 3.6
dipeptidyl peptidase IV 3.5
phosphoinositide 3-kinase 3.5
NOS 3.5
chymopapain 3.5
tryptophan 2,3-dioxygenase 3.5
MEK 3.5
choline kinase 3.5
PDK1 3.4
p100 3.4
SCP 3.4
AMP-activated kinase 3.4
STK11 3.4
uroporphyrinogen decarboxylase 3.4
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
plasmin 3.3
PTPase 3.3
TGT 3.2
farnesyltransferase 3.2
CNPase 3.2
phosphoglycerate kinase 3.2
matrix metalloproteinase 9 3.1
CEP 3.1
reverse transcriptase 3.1
CDH 3.1
aldehyde dehydrogenase 3.1
aldehyde dehydrogenase 3.0
MTD 3.0
mitogen-activated protein kinase 3.0
NAT 2.9
neutral sphingomyelinase 2.9
transcriptase 2.8
argininosuccinate synthetase 2.8
adenine phosphoribosyltransferase 2.8
GCA 2.8
deoxycytidine kinase 2.8
indoleamine 2,3-dioxygenase 2.8
farnesyltransferase 2.7
SST 2.7
caspase-2 2.6
microsomal epoxide hydrolase 2.6
TAT 2.6
caspase-2 2.6
MIP 2.6
MAP 2.6
BAT 2.5
DTA 2.5
GSK 2.5
TSP-1 2.5
protein kinase C 2.5
tryptophan hydroxylase 2.5
BMT 2.5
Pla 2.4
RNase 2.4
3beta-hydroxysteroid dehydrogenase 2.4
GAS 2.3
BAL 2.3
caspase-3 2.2
succinate dehydrogenase 2.2
angiotensin-converting enzyme 2 2.2
RNase 2.2
protein kinase 2.2
phospholipase C 2.2
APC 2.2
MDR 2.1
P-glycoprotein 2.1
GRK5 2.1
thioredoxin reductase 2.0
RNase T1 2.0
PARP 2.0
DNA methyltransferase 2.0
CPS 1.9
choline acetyltransferase 1.9
heparinase 1.9
alkaline phosphatase 1.9
NADPH-diaphorase 1.9
NO synthase 1.9
myosin light chain kinase 1.8
caspase-8 1.8
cdc2 1.8
firefly luciferase 1.8
heme oxygenase 1.8
MMP 1.8
peroxidase 1.8
gamma-glutamylcysteine synthetase 1.8
beta-galactosidase 1.7
DAT 1.7
AST 1.7
glucose-6-phosphatase 1.7
isocitrate dehydrogenase 1.6
CYP3A4 1.6
PAL 1.6
tyrosine hydroxylase 1.6
ribonuclease 1.6
ribonuclease 1.5
guanylate cyclase 1.5
phosphoglucose isomerase 1.5
isocitrate dehydrogenase 1.5
HSD 1.5
luciferase 1.5
glutathione S-transferase 1.5
urokinase-type plasminogen activator 1.4
cathepsin G 1.4
prolyl hydroxylase 1.4
elastase 1.4
endoglycosidase H 1.4
topoisomerase 1.4
prostaglandin synthetase 1.4
MEKK1 1.4
carbonic anhydrase 1.4
MPP 1.4
caspase-9 1.4
more...
Compound
Nevadensin 9.9
W37 8.7
2,4-pyrimidinediamine 8.5
Neomycin sulfate 8.0
Neomycin sulfate 7.8
Hymenialdisine 7.6
ONB 7.4
2,4-dihydroxybenzaldehyde 7.3
2,4-dihydroxybenzaldehyde 7.2
Janus Green B 7.2
Nickel sulfate 7.2
2,4-dihydroxybenzaldehyde 7.2
TKB 6.8
Theaflavin 6.8
Allethrin 6.7
Aloin 6.7
Oxindole 6.7
Ginsenoside Re 6.5
dUDP 6.4
DMP 6.3
Aloin 6.3
DMP 6.3
DX-52-1 6.3
DMP 6.3
CD 3 6.2
Geniposide 6.0
Temsirolimus 5.9
CMK 5.9
Cromolyn 5.9
A 99 5.8
Cbl 5.8
Toluidine blue 5.8
TEL 5.8
Deoxyspergualin 5.7
Guanidinoacetic acid 5.7
Homoharringtonine 5.7
ABL 5.7
ED 20 5.7
Latrunculin B 5.6
GC-1 5.5
LTC4 5.5
BCR 5.5
Oil Red 5.5
HPC 5.5
Reticulin 5.5
NIX 5.5
3-methylpyridine 5.4
DHM 5.4
HPC 5.4
SDZ PSC 833 5.4
Polybrene 5.4
HMBA 5.3
NFS 5.3
S-allylcysteine 5.2
A 150 5.2
Evodiamine 5.2
Rhodamine 123 5.1
VLA 5.1
HPP 5.1
Florid 5.1
Evodiamine 5.1
2-hydroxybenzaldehyde 5.0
Esculetin 5.0
Benzidine 5.0
SHS 5.0
phthalazine 5.0
Hoechst 33342 5.0
Tyrosine 5.0
DMP 4.9
HMBA 4.9
Wortmannin 4.9
methoxyacetic acid 4.8
DAPT 4.8
Nobiletin 4.7
Hematoxylin 4.7
tyrosine 4.7
BAL 4.6
Sudan IV 4.6
K19 4.6
MGA 4.6
tris(2-chloroethyl) phosphate 4.6
MK-329 4.6
Magnolol 4.5
Glycyrrhetinic acid 4.5
Cyclopiazonic acid 4.5
Melanin 4.5
DPM 4.5
EPC 4.4
Ara-C 4.4
Chelerythrine 4.4
Chelerythrine 4.4
Ara-C 4.4
PGD2 4.3
Guanine 4.3
BUdR 4.3
Nitro-L-arginine 4.3
Busulfan 4.3
Geldanamycin 4.3
Mirtazapine 4.2
Lithium chloride 4.2
SAN 4.2
TACE 4.2
BON 4.1
AF-2 4.1
SN-38 4.1
A 71 4.1
Malate 4.1
LY 294002 4.1
ITC 4.1
MPB 4.1
Letrozole 4.0
Protamine 4.0
Chrysin 4.0
Loperamide 4.0
Ursodeoxycholic acid 4.0
CPA 4.0
Psoralen 4.0
Fluo-3 3.9
Ach 3.9
Vimentin 3.9
TIB 3.9
8-Br-cGMP 3.9
CPA 3.9
MEK 3.8
Codeine 3.8
CPA 3.8
Trypan Blue 3.8
DHB 3.8
quinazoline 3.7
quinazoline 3.7
Permethrin 3.7
HEI 3.7
Poly I 3.7
PAE 3.6
ENU 3.6
Calcein 3.6
Piroxicam 3.6
CPA 3.6
Bisulfite 3.5
Genistein 3.5
TGT 3.5
GAP 3.5
Fumarate 3.5
APS 3.5
Morin 3.5
AAF 3.5
5-Azacytidine 3.5
Dibutyryl cyclic AMP 3.5
Dibutyryl cyclic AMP 3.5
HCP 3.5
DPG 3.4
Fucoidan 3.4
Diazoxide 3.4
Malachite Green 3.4
BIC 3.4
retinoic acid 3.3
Emodin 3.3
Naringin 3.3
2-furaldehyde 3.3
Eosin 3.3
more...