Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P10636 (
tau protein
)
5,110
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tau protein
5110
amyloid precursor protein
545
Mol
436
Sep
290
axonal
281
ubiquitin
196
amyloid beta
186
GSK
176
APP
146
microtubule-associated protein
144
threonine
115
prion
106
synuclein
102
apolipoprotein E
101
CSF
100
progranulin
99
phosphatase
96
GRN
94
14-3-3
87
insulin
86
alpha-synuclein
79
APOE
75
C9orf72
73
SNCA
73
caspase-3
73
microtubule associated protein
72
TDP-43
70
CA1
68
TAU
67
PSEN1
60
proteasome
60
FTD
59
calpain
59
glial fibrillary acidic protein
58
MRI
57
ATP
57
Glycogen synthase
51
SDS
51
cyclin-dependent kinase 5
50
prion protein
49
acetylcholinesterase
49
LRRK2
48
endoplasmic reticulum
47
p25
46
PS1
44
NMR
44
alkaline phosphatase
44
p35
44
VCP
43
amyloid protein
43
MAP2
42
ACS
41
BACE1
40
FUS
40
fused
38
CA3
37
PSEN2
37
TARDBP
36
synaptophysin
35
protein phosphatase
34
brain-derived neurotrophic factor
34
glucocerebrosidase
33
glycogen synthase kinase 3
33
MAPK
33
p38
33
nerve growth factor
33
phosphorylating
32
olfactory
31
GSK3
31
with Parkinsonism
31
mTOR
31
14-3-3 protein
30
precursor protein
30
polypeptide
29
PrP
29
PI3K
28
cytokine
28
CHMP2B
28
TNF
28
p62
27
more...
Disease
Alzheimer's disease
3360
dementia
1203
progressive supranuclear palsy
321
Parkinson's disease
321
parkinsonism
295
cognitive impairment
292
neuroblastoma
157
amyotrophic lateral sclerosis
128
plaque
128
Pick's disease
124
Tauopathies
102
Frontotemporal dementia
89
diabetes
77
memory impairment
76
Creutzfeldt-Jakob disease
71
encephalopathy
70
aphasia
65
cancer
64
SDS
51
brain atrophy
49
motor neuron disease
44
tumor
42
Down syndrome
42
Huntington's disease
41
FUS
40
depression
39
ischemia
39
stroke
36
FTLD
33
Dementia with Lewy bodies
33
vascular disease
32
type 2 diabetes
27
amyloidosis
27
sarcoma
26
cerebral ischemia
25
multiple sclerosis
23
apraxia
23
breast cancer
22
senile dementia
21
cold
21
epilepsy
21
Corticobasal degeneration
20
neurological disease
19
obesity
18
cognitive deficit
18
disinhibition
17
PSP
14
amnesia
14
hyperglycemia
14
Bielschowsky
13
cardiovascular disease
13
pheochromocytoma
13
movement disorder
13
atherosclerosis
13
muscular atrophy
12
PARK2
12
psychosis
11
hypertension
11
myopathy
11
Gerstmann
11
schizophrenia
11
hydrocephalus
10
GSH
10
IBM
10
hyperhomocysteinemia
9
CJD
9
glaucoma
9
PDC
9
brain disorder
8
presenile dementia
8
herpes simplex
8
degenerative disease
8
tumorigenesis
8
hyperinsulinemia
8
virus infection
7
fits
7
tumor growth
7
mutism
7
varices
7
major depressive disorder
7
more...
Symptom
memory loss
68
seizures
32
myoclonus
26
dystonia
19
hypothermia
18
tremor
18
anesthesia
14
apathy
13
bradykinesia
13
ataxia
12
collapse
10
weakness
9
cerebellar ataxia
9
pain
7
starvation
7
dysarthria
6
hypotonia
6
insomnia
5
forgetfulness
4
personality change
4
ophthalmoplegia
4
thinning
4
fatigue
4
lethargy
3
dizziness
3
acidity
3
fasciculation
3
functional recovery
2
chorea
2
paraparesis
2
agitation
2
hypercapnia
2
vertigo
2
acute stress
2
motor symptom
2
dyspnea
2
headache
2
visual hallucination
2
discomfort
1
nasal discharge
1
anorexia
1
metamorphopsia
1
prostration
1
discomfort
1
stridor
1
HSA
1
spasticity
1
respiratory distress
1
blurred vision
1
ACHE
1
anosmia
1
ataxic gait
1
Behavioral symptoms
1
shortness of breath
1
menopausal symptoms
1
Decreased activity
1
abnormal gait
1
diarrhea
1
Involuntary Movement
1
analgesia
1
catatonia
1
rundown
1
paresis
1
Spots
1
stigma
1
consciousness disturbance
1
tonic-clonic seizure
1
amimia
1
Drug
CSF
100
lysine
52
MAP
22
ROS
12
vitamin E
10
Parkin
9
Parkin
9
Taxol
8
Frontal
8
ROC
8
Methylene blue
6
Leaf
6
Biopolymers
5
Monit
4
caffeine
4
Gel
4
PPA
4
ascorbate
4
FAD
4
Immune globulin
3
Glucagon
3
Ginseng
3
Pronase
3
DM1
3
p75
3
DNase I
3
GEO
3
Spectrum
2
L-tyrosine
2
CTX
2
MDS
2
ABC
2
Spectrum
2
Donepezil
2
CTX
2
Simvastatin
2
NAG
2
IL-1ra
2
Paraffin
2
CTX
2
Liraglutide
1
DFP
1
Tolfenamic acid
1
Tibolone
1
Artemether
1
Aluminum chloride
1
Tramiprosate
1
CaCl2
1
CaCl2
1
Phosphatidylserine
1
K-252a
1
Bexarotene
1
Asn
1
Histamine
1
Itraconazole
1
Lovastatin
1
Glide
1
Kainic acid
1
Vitamin K
1
Kenyan
1
CTA
1
AraC
1
CaCl2
1
ADM
1
Alsterpaullone
1
Ouabain
1
Salbutamol
1
Check
1
RFP
1
Vitamin B12
1
DHT
1
CTC
1
Glutathione
1
DPA
1
NADH
1
citric acid
1
balanced salt solution
1
Hymenialdisine
1
PFA
1
Sodium nitroprusside
1
more...
Enzyme
protein kinase
318
GSK
243
mitogen-activated protein kinase
123
calcineurin
96
acetylcholinesterase
67
caspase-3
61
proteasome
60
cdc2
57
protein phosphatase 2A
47
alkaline phosphatase
44
ACS
41
ERK
41
protein kinase C
32
CaMKII
28
cholinesterase
28
superoxide dismutase
26
AMPK
21
MAP
21
kinesin
20
choline acetyltransferase
17
enolase
16
IKK
16
focal adhesion kinase
15
peroxidase
14
lactate dehydrogenase
14
catalase
13
ATPase
12
luciferase
12
AMP-activated protein kinase
12
tyrosine hydroxylase
12
beta-secretase
11
MEK
11
phosphatidylinositol 3-kinase
11
complex I
11
cathepsin D
10
CD10
10
transglutaminase
9
ACE
8
RNA polymerase
8
trypsin
8
caspase-9
7
pyruvate dehydrogenase
7
proteinase K
7
pyruvate dehydrogenase
7
monoamine oxidase
7
pyruvate dehydrogenase
7
phosphodiesterase
7
reverse transcriptase
6
isopeptidase
6
Thy1
6
peptidyl-prolyl cis-trans isomerase
6
glutathione S-transferase
6
glyceraldehyde-3-phosphate dehydrogenase
6
glyceraldehyde-3-phosphate dehydrogenase
6
CDR
6
AMPK
6
phosphoinositide 3-kinase
5
glutathione peroxidase
5
thrombin
5
glyceraldehyde-3-phosphate dehydrogenase
5
chymotrypsin
5
P-glycoprotein
5
cathepsin B
5
glyceraldehyde-3-phosphate dehydrogenase
5
glyceraldehyde-3-phosphate dehydrogenase
5
insulin-degrading enzyme
4
NOS
4
mu-calpain
4
subtilisin
4
PARP
4
gamma-glutamyl transpeptidase
4
transcriptase
4
NQO1
4
NO synthase
4
AGT
4
caspase-2
3
NADPH-diaphorase
3
cytochrome oxidase
3
DAT
3
phosphorylase kinase
3
more...
Compound
Dec
314
threonine
192
calcium
167
serine
154
DNA
154
water
141
oxygen
97
glucose
92
Clin
92
proline
86
glutamate
82
tyrosine
81
phosphate
71
lysine
65
silver
59
ATP
57
Neuronal
52
Glycogen synthase
51
SDS
51
sodium
43
sulfate
42
ACS
41
ACS
41
hydrogen
40
iron
39
alanine
32
zinc
29
TNF
28
cysteine
27
copper
25
nitric oxide
24
cAMP
24
arginine
23
aluminum
23
MAP
22
GlcNAc
22
retinoic acid
22
acetate
21
TDP
21
Asp
20
NMDA
19
homocysteine
17
Ubiquitin
16
MTT
16
AMP
16
Congo red
16
leucine
15
formic acid
14
formic acid
14
formic acid
14
formic acid
14
formic acid
14
formic acid
14
formic acid
14
salt
14
glutamine
14
formic acid
14
PSP
14
formic acid
14
COS
14
formic acid
14
methionine
13
nitrogen
12
His
12
Insulin
12
galactose
12
Lithium
12
phosphoserine
12
GSH
11
potassium
11
GSH
11
tryptophan
10
selenium
10
manganese
10
valine
10
formaldehyde
10
tryptophan
10
CHIP
10
tryptophan
9
urea
9
more...