Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P10636 (
tau protein
)
5,110
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tau protein
5110
amyloid precursor protein
545
Mol
436
Sep
290
axonal
281
ubiquitin
196
amyloid beta
186
GSK
176
APP
146
microtubule-associated protein
144
threonine
115
prion
106
synuclein
102
apolipoprotein E
101
CSF
100
progranulin
99
phosphatase
96
GRN
94
14-3-3
87
insulin
86
alpha-synuclein
79
APOE
75
C9orf72
73
SNCA
73
caspase-3
73
microtubule associated protein
72
TDP-43
70
CA1
68
TAU
67
proteasome
60
PSEN1
60
FTD
59
calpain
59
glial fibrillary acidic protein
58
ATP
57
MRI
57
Glycogen synthase
51
SDS
51
cyclin-dependent kinase 5
50
prion protein
49
more...
Disease
Alzheimer's disease
3360
dementia
1203
progressive supranuclear palsy
321
Parkinson's disease
321
parkinsonism
295
cognitive impairment
292
neuroblastoma
157
amyotrophic lateral sclerosis
128
plaque
128
Pick's disease
124
Tauopathies
102
Frontotemporal dementia
89
diabetes
77
memory impairment
76
Creutzfeldt-Jakob disease
71
encephalopathy
70
aphasia
65
cancer
64
SDS
51
brain atrophy
49
motor neuron disease
44
tumor
42
Down syndrome
42
Huntington's disease
41
FUS
40
depression
39
ischemia
39
stroke
36
FTLD
33
Dementia with Lewy bodies
33
vascular disease
32
amyloidosis
27
type 2 diabetes
27
sarcoma
26
cerebral ischemia
25
multiple sclerosis
23
apraxia
23
breast cancer
22
senile dementia
21
cold
21
more...
Symptom
memory loss
68
seizures
32
myoclonus
26
dystonia
19
tremor
18
hypothermia
18
anesthesia
14
bradykinesia
13
apathy
13
ataxia
12
collapse
10
weakness
9
cerebellar ataxia
9
pain
7
starvation
7
hypotonia
6
dysarthria
6
insomnia
5
fatigue
4
personality change
4
thinning
4
forgetfulness
4
ophthalmoplegia
4
fasciculation
3
dizziness
3
lethargy
3
acidity
3
functional recovery
2
chorea
2
acute stress
2
dyspnea
2
hypercapnia
2
agitation
2
vertigo
2
paraparesis
2
motor symptom
2
headache
2
visual hallucination
2
discomfort
1
anorexia
1
more...
Drug
CSF
100
lysine
52
MAP
22
ROS
12
vitamin E
10
Parkin
9
Parkin
9
Frontal
8
ROC
8
Taxol
8
Methylene blue
6
Leaf
6
Biopolymers
5
FAD
4
ascorbate
4
Gel
4
caffeine
4
Monit
4
PPA
4
p75
3
Immune globulin
3
Glucagon
3
DNase I
3
DM1
3
Pronase
3
Ginseng
3
GEO
3
CTX
2
Donepezil
2
NAG
2
Simvastatin
2
CTX
2
Paraffin
2
IL-1ra
2
Spectrum
2
MDS
2
ABC
2
CTX
2
L-tyrosine
2
Spectrum
2
more...
Enzyme
protein kinase
318
GSK
243
mitogen-activated protein kinase
123
calcineurin
96
acetylcholinesterase
67
caspase-3
61
proteasome
60
cdc2
57
protein phosphatase 2A
47
alkaline phosphatase
44
ERK
41
ACS
41
protein kinase C
32
cholinesterase
28
CaMKII
28
superoxide dismutase
26
AMPK
21
MAP
21
kinesin
20
choline acetyltransferase
17
IKK
16
enolase
16
focal adhesion kinase
15
peroxidase
14
lactate dehydrogenase
14
catalase
13
ATPase
12
AMP-activated protein kinase
12
luciferase
12
tyrosine hydroxylase
12
MEK
11
phosphatidylinositol 3-kinase
11
beta-secretase
11
complex I
11
cathepsin D
10
CD10
10
transglutaminase
9
RNA polymerase
8
ACE
8
trypsin
8
more...
Compound
Dec
314
threonine
192
calcium
167
serine
154
DNA
154
water
141
oxygen
97
Clin
92
glucose
92
proline
86
glutamate
82
tyrosine
81
phosphate
71
lysine
65
silver
59
ATP
57
Neuronal
52
SDS
51
Glycogen synthase
51
sodium
43
sulfate
42
ACS
41
ACS
41
hydrogen
40
iron
39
alanine
32
zinc
29
TNF
28
cysteine
27
copper
25
nitric oxide
24
cAMP
24
aluminum
23
arginine
23
GlcNAc
22
retinoic acid
22
MAP
22
acetate
21
TDP
21
Asp
20
more...