Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10636 (tau protein)
 5,110 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tau protein 5110
amyloid precursor protein 545
Mol 436
Sep 290
axonal 281
ubiquitin 196
amyloid beta 186
GSK 176
APP 146
microtubule-associated protein 144
threonine 115
prion 106
synuclein 102
apolipoprotein E 101
CSF 100
progranulin 99
phosphatase 96
GRN 94
14-3-3 87
insulin 86
alpha-synuclein 79
APOE 75
SNCA 73
C9orf72 73
caspase-3 73
microtubule associated protein 72
TDP-43 70
CA1 68
TAU 67
proteasome 60
PSEN1 60
calpain 59
FTD 59
glial fibrillary acidic protein 58
ATP 57
MRI 57
Glycogen synthase 51
SDS 51
cyclin-dependent kinase 5 50
prion protein 49
acetylcholinesterase 49
LRRK2 48
endoplasmic reticulum 47
p25 46
NMR 44
p35 44
alkaline phosphatase 44
PS1 44
amyloid protein 43
VCP 43
MAP2 42
ACS 41
FUS 40
BACE1 40
fused 38
CA3 37
PSEN2 37
TARDBP 36
synaptophysin 35
brain-derived neurotrophic factor 34
protein phosphatase 34
glycogen synthase kinase 3 33
MAPK 33
nerve growth factor 33
glucocerebrosidase 33
p38 33
phosphorylating 32
GSK3 31
mTOR 31
with Parkinsonism 31
olfactory 31
14-3-3 protein 30
precursor protein 30
polypeptide 29
PrP 29
PI3K 28
TNF 28
cytokine 28
CHMP2B 28
p62 27
myelin basic protein 26
DNA-binding protein 25
PP2A 25
presenilin 1 25
NMDA receptor 25
protein kinase B 24
calmodulin 24
calcineurin 24
JNK 24
PDB 23
tumor necrosis factor 23
cyclin 23
MAP kinase 23
glycogen synthase kinase 3 beta 23
microtubule-associated protein 2 23
Hsp90 22
PRNP 22
CDK5 22
MAP 21
tyrosine kinase 21
ALS 21
Bcl-2 21
ERK1 21
TAR DNA-binding protein 43 21
kinesin 20
neuron-specific enolase 20
TREM2 20
alternatively spliced 20
huntingtin 19
Pin1 19
IL-6 19
cyclin-dependent kinase 19
p53 19
proline-rich 19
phosphoprotein 19
PKA 18
neurofilament protein 18
Apolipoprotein E 18
cytoskeletal protein 17
choline acetyltransferase 17
BACE 17
histone 17
SOD1 17
mitogen-activated protein 17
beta-tubulin 17
PINK1 16
leucine-rich repeat kinase 2 16
heat shock protein 16
Ubiquitin 16
STH 16
superoxide dismutase 16
PHF6 16
serine/threonine kinase 16
AMP 15
cAMP-dependent protein kinase 15
CA2 15
ERK 15
AKT 15
enolase 15
NF-H 15
LC3 14
lipopolysaccharide 14
PSP 14
vimentin 14
parkin 14
SOD 14
lactate dehydrogenase 14
CaMKII 14
chromosome 21 14
serum albumin 14
DJ-1 14
cathepsin D 13
dimeric 13
glutamate receptor 13
crystallin 13
TBK1 13
presenilin 2 13
Cyclin-dependent kinase 5 13
brain-derived 13
PHF1 13
more...
Disease
Alzheimer's disease 3360
dementia 1203
Parkinson's disease 321
progressive supranuclear palsy 321
parkinsonism 295
cognitive impairment 292
neuroblastoma 157
plaque 128
amyotrophic lateral sclerosis 128
Pick's disease 124
Tauopathies 102
Frontotemporal dementia 89
diabetes 77
memory impairment 76
Creutzfeldt-Jakob disease 71
encephalopathy 70
aphasia 65
cancer 64
SDS 51
brain atrophy 49
motor neuron disease 44
tumor 42
Down syndrome 42
Huntington's disease 41
FUS 40
ischemia 39
depression 39
stroke 36
FTLD 33
Dementia with Lewy bodies 33
vascular disease 32
amyloidosis 27
type 2 diabetes 27
sarcoma 26
cerebral ischemia 25
multiple sclerosis 23
apraxia 23
breast cancer 22
epilepsy 21
senile dementia 21
cold 21
Corticobasal degeneration 20
neurological disease 19
obesity 18
cognitive deficit 18
disinhibition 17
amnesia 14
PSP 14
hyperglycemia 14
cardiovascular disease 13
movement disorder 13
pheochromocytoma 13
Bielschowsky 13
atherosclerosis 13
muscular atrophy 12
PARK2 12
hypertension 11
schizophrenia 11
Gerstmann 11
psychosis 11
myopathy 11
GSH 10
hydrocephalus 10
IBM 10
hyperhomocysteinemia 9
glaucoma 9
CJD 9
PDC 9
presenile dementia 8
tumorigenesis 8
degenerative disease 8
herpes simplex 8
hyperinsulinemia 8
brain disorder 8
bipolar disorder 7
tumor growth 7
mutism 7
virus infection 7
akinesia 7
familial Alzheimer disease 7
autism 7
Blocking 7
fits 7
carcinoma 7
metabolic syndrome 7
major depressive disorder 7
developmental delay 7
sleep disturbances 7
varices 7
scrapie 6
Pineal 6
mental retardation 6
worms 6
spongiform encephalopathy 6
hallucinations 6
encephalitis 6
meningoencephalitis 6
mental retardation 6
glioma 6
AD2 6
mole 6
TEM 6
mole 6
neuritis 6
leukoencephalopathy 6
NPC 6
TEM 6
type 1 diabetes 6
FTD-ALS 5
DM1 5
PARK7 5
dysphagia 5
glucose intolerance 5
temporal lobe epilepsy 5
Still 5
autoimmune disease 5
aggression 5
infectious diseases 5
Niemann-Pick 5
coma 5
hypoglycemia 5
delusions 4
status epilepticus 4
cerebral degeneration 4
cytomegalovirus 4
anomia 4
posttraumatic stress disorder 4
Chlamydia 4
pseudobulbar palsy 4
blindness 4
neuropathy 4
disorientation 4
leukemia 4
epithelial ovarian cancer 4
Duchenne muscular dystrophy 4
familial disorder 4
MRS 4
sleep apnea 4
Neuroblastoma 4
PARK1 4
Neuroblastoma 4
Neurodegenerative Disorders 4
malaria 4
brain dysfunction 4
macular degeneration 4
subacute sclerosing panencephalitis 4
DRD 3
Dissociation 3
Vascular dementia 3
brain cancer 3
prostate cancer 3
Ewing's sarcoma 3
myositis 3
Multiple system atrophy 3
PDD 3
B-cell lymphoma 3
sleep disorders 3
Schmidt 3
AS1 3
ICP 3
more...
Symptom
memory loss 68
seizures 32
myoclonus 26
dystonia 19
hypothermia 18
tremor 18
anesthesia 14
apathy 13
bradykinesia 13
ataxia 12
collapse 10
weakness 9
cerebellar ataxia 9
pain 7
starvation 7
dysarthria 6
hypotonia 6
insomnia 5
forgetfulness 4
personality change 4
ophthalmoplegia 4
thinning 4
fatigue 4
lethargy 3
dizziness 3
acidity 3
fasciculation 3
functional recovery 2
chorea 2
paraparesis 2
agitation 2
hypercapnia 2
vertigo 2
acute stress 2
motor symptom 2
dyspnea 2
headache 2
visual hallucination 2
discomfort 1
nasal discharge 1
anorexia 1
metamorphopsia 1
prostration 1
discomfort 1
stridor 1
HSA 1
spasticity 1
respiratory distress 1
blurred vision 1
ACHE 1
anosmia 1
ataxic gait 1
Behavioral symptoms 1
shortness of breath 1
menopausal symptoms 1
Decreased activity 1
abnormal gait 1
diarrhea 1
Involuntary Movement 1
analgesia 1
catatonia 1
rundown 1
paresis 1
Spots 1
stigma 1
consciousness disturbance 1
tonic-clonic seizure 1
amimia 1
Drug
CSF 100
lysine 52
MAP 22
ROS 12
vitamin E 10
Parkin 9
Parkin 9
ROC 8
Frontal 8
Taxol 8
Methylene blue 6
Leaf 6
Biopolymers 5
ascorbate 4
caffeine 4
FAD 4
Gel 4
PPA 4
Monit 4
DM1 3
p75 3
Glucagon 3
Immune globulin 3
Ginseng 3
Pronase 3
DNase I 3
GEO 3
Spectrum 2
MDS 2
CTX 2
CTX 2
Simvastatin 2
Paraffin 2
Donepezil 2
NAG 2
IL-1ra 2
Spectrum 2
ABC 2
L-tyrosine 2
CTX 2
Liraglutide 1
DFP 1
Tolfenamic acid 1
Tibolone 1
Artemether 1
Aluminum chloride 1
Tramiprosate 1
CaCl2 1
CaCl2 1
Phosphatidylserine 1
K-252a 1
Bexarotene 1
Asn 1
Histamine 1
Itraconazole 1
4-Hydroxytamoxifen 1
Gelfoam 1
Glide 1
ACT 1
Vitamin K 1
Kenyan 1
Ouabain 1
Tocopherol 1
AraC 1
CaCl2 1
ADM 1
Alsterpaullone 1
Retinoic acid 1
Salbutamol 1
Check 1
RFP 1
Vitamin B12 1
DHT 1
Lovastatin 1
NADH 1
DHT 1
HCH 1
CTC 1
Kainic acid 1
CFT 1
Glutathione 1
DPA 1
Forskolin 1
9-THC 1
CTA 1
nitroglycerin 1
MRC 1
balanced salt solution 1
Hymenialdisine 1
PFA 1
Sodium nitroprusside 1
Fragment 1
CTC 1
Propofol 1
ETA 1
Premarin 1
NBT 1
Pravastatin 1
citric acid 1
Ethanol 1
EPL 1
Atomoxetine 1
Estrogens 1
PCP 1
Portal 1
Enzyme
protein kinase 318
GSK 243
mitogen-activated protein kinase 123
calcineurin 96
acetylcholinesterase 67
caspase-3 61
proteasome 60
cdc2 57
protein phosphatase 2A 47
alkaline phosphatase 44
ERK 41
ACS 41
protein kinase C 32
cholinesterase 28
CaMKII 28
superoxide dismutase 26
AMPK 21
MAP 21
kinesin 20
choline acetyltransferase 17
IKK 16
enolase 16
focal adhesion kinase 15
peroxidase 14
lactate dehydrogenase 14
catalase 13
tyrosine hydroxylase 12
luciferase 12
AMP-activated protein kinase 12
ATPase 12
MEK 11
complex I 11
phosphatidylinositol 3-kinase 11
beta-secretase 11
CD10 10
cathepsin D 10
transglutaminase 9
trypsin 8
RNA polymerase 8
ACE 8
pyruvate dehydrogenase 7
monoamine oxidase 7
caspase-9 7
pyruvate dehydrogenase 7
proteinase K 7
pyruvate dehydrogenase 7
phosphodiesterase 7
CDR 6
peptidyl-prolyl cis-trans isomerase 6
glyceraldehyde-3-phosphate dehydrogenase 6
AMPK 6
reverse transcriptase 6
glutathione S-transferase 6
glyceraldehyde-3-phosphate dehydrogenase 6
isopeptidase 6
Thy1 6
chymotrypsin 5
cathepsin B 5
glyceraldehyde-3-phosphate dehydrogenase 5
glyceraldehyde-3-phosphate dehydrogenase 5
glyceraldehyde-3-phosphate dehydrogenase 5
thrombin 5
P-glycoprotein 5
glutathione peroxidase 5
phosphoinositide 3-kinase 5
NO synthase 4
mu-calpain 4
subtilisin 4
AGT 4
PARP 4
gamma-glutamyl transpeptidase 4
NQO1 4
transcriptase 4
insulin-degrading enzyme 4
NOS 4
caspase-2 3
NADPH-diaphorase 3
phosphorylase kinase 3
glucocerebrosidase 3
alcohol dehydrogenase 3
caspase-2 3
heme oxygenase 3
CYP46A1 3
CYP3A4 3
ATP synthase 3
CLK1 3
MPP 3
cytochrome oxidase 3
DAT 3
alanine aminotransferase 3
O-GlcNAc transferase 3
glutamine synthetase 2
topoisomerase 2
caspase-8 2
topoisomerase 2
CNPase 2
phospholipase C 2
diaphorase 2
malate dehydrogenase 2
ascorbate oxidase 2
aldolase 2
diaphorase 2
PDK1 2
NADPH oxidase 2
glutathione reductase 2
RNase 2
MEKK1 2
m-calpain 2
firefly luciferase 2
heparinase 2
RNase 2
caspase-1 2
NADPH oxidase 2
cathepsin L 2
PGM 2
guanylate cyclase 2
prolyl hydroxylase 2
lipoxygenase 2
beta-galactosidase 2
phosphorylase 2
alanine aminopeptidase 2
tissue plasminogen activator 2
hypoxanthine-guanine phosphoribosyltransferase 2
Omi/HtrA2 2
DNA polymerase 2
granzyme B 1
biliverdin reductase 1
hexokinase 1
phospholipase A2 1
nicotinamide phosphoribosyltransferase 1
caspase-4 1
ceruloplasmin 1
glutamate decarboxylase 1
neuropathy target esterase 1
ubiquitin-protein ligase 1
MMP 1
GRK2 1
ricin 1
CEP 1
tyrosinase 1
neuropsin 1
collagenase 1
sialidase 1
NADH dehydrogenase 1
neuropsin 1
arachidonate 5-lipoxygenase 1
chloroperoxidase 1
endoproteinase Glu-C 1
phospholipid hydroperoxide glutathione peroxidase 1
histone acetyltransferase 1
ribonuclease 1
renin 1
prolyl endopeptidase 1
prenyltransferase 1
chitinase 1
caspase-6 1
15-lipoxygenase 1
carbonic anhydrase 1
ribonuclease 1
hexosaminidase 1
more...
Compound
Dec 314
threonine 192
calcium 167
serine 154
DNA 154
water 141
oxygen 97
Clin 92
glucose 92
proline 86
glutamate 82
tyrosine 81
phosphate 71
lysine 65
silver 59
ATP 57
Neuronal 52
Glycogen synthase 51
SDS 51
sodium 43
sulfate 42
ACS 41
ACS 41
hydrogen 40
iron 39
alanine 32
zinc 29
TNF 28
cysteine 27
copper 25
cAMP 24
nitric oxide 24
aluminum 23
arginine 23
GlcNAc 22
retinoic acid 22
MAP 22
acetate 21
TDP 21
Asp 20
NMDA 19
homocysteine 17
MTT 16
AMP 16
Congo red 16
Ubiquitin 16
leucine 15
formic acid 14
formic acid 14
COS 14
formic acid 14
formic acid 14
formic acid 14
formic acid 14
formic acid 14
PSP 14
formic acid 14
salt 14
formic acid 14
glutamine 14
formic acid 14
methionine 13
Insulin 12
Lithium 12
nitrogen 12
galactose 12
His 12
phosphoserine 12
GSH 11
potassium 11
GSH 11
manganese 10
CHIP 10
formaldehyde 10
selenium 10
tryptophan 10
valine 10
tryptophan 10
urea 9
tryptophan 9
Glutamate 9
aspartic acid 9
Okadaic acid 9
TAR 9
perchloric acid 9
tryptophan 9
Gly 8
aspartic acid 8
aspartic acid 8
Melatonin 8
ethanol 8
aspartic acid 8
STZ 8
Methylene blue 7
Cereb 7
Glycogen 7
formaldehyde 7
guanidine 7
RD4 7
Curcumin 7
Isoform 7
ammonium 7
PEG 7
dUTP 7
TOF 7
AMPA 7
fluorine 7
MEK 7
MPTP 7
K19 7
TEM 6
Serine 6
glycerol 6
ADP 6
DMSO 6
8-OHdG 6
FK506 6
Adenine 6
iodine 6
Tris 6
ADP 6
ADP 6
H2O2 5
Tris 5
bromide 5
L-threonine 5
Heparin 5
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 5
Memantine 5
GTP 5
NH2 5
acetyl-CoA 5
ANS 5
EDTA 5
Ile 5
ANS 5
PEG 5
Phe 5
nicotinamide 5
asparagine 5
Paclitaxel 5
5-HT 5
EDTA 4
Homocysteine 4
2-nonenal 4
Mg2+ 4
L-DOPA 4
PPA 4
GABA 4
FAD 4
HCl 4
CO2 4
GABA 4
PAC 4
Colchicine 4
Homocysteine 4
PPA 4
gamma-aminobutyric acid 4
Thioflavin T 4
nickel 4
more...