Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10415 (Bcl-2)
 33,771 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Adenomatoid odontogenic tumor (AOT) is a relatively rare benign tumor, accounting for 2% to 7% of odontogenic tumors. AOT is generally found in the incisor region of the maxilla of young women. It is often misdiagnosed as a dentigerous cyst. We report a case of AOT during pregnancy. The patient was a 21-year-old Philippine woman who complained of a swelling in the right maxillary gingival; the swelling rapidly enlarged during pregnancy. We enucleated the tumor and the impacted canine, with the patient under general anesthesia. Histological examination revealed a pseudoglandular structure with odontogenic appearance. On the basis of these findings and the World health organization (WHO) classification, we diagnosed the tumor as an adenomatoid odontogenic tumor. The tumor cells were identified by an immunohistochemically positive reaction for Bcl-2 and estrogen receptor. The MIB-1 labeling index was less than 1%. There has been no sign of recurrence as of 1.5 years after the operation.
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PMID:Case of adenomatid odontogenic tumor during pregnancy. 2216 95