Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10145 (IL-8)
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Human Gene/Protein
Claudin 15 10.4
secretory carrier membrane protein 4 10.4
ChemR13 10.4
RNASE8 10.4
CCDC69 10.4
Bladder cancer associated protein 10.4
C1orf51 10.4
GCN5-related, putative 10.4
PCDHB11 10.4
FLJ38348 10.4
TCEAL2 10.4
ZNF510 10.4
DEFB131 10.4
OR5M11 10.4
GTF3C4 10.4
IL8R2 10.4
phorbolin 1 10.4
toll-like receptor adaptor molecule 2 10.4
C5orf13 10.4
phorbolin 2 10.4
IGSF22 10.4
Defensin-6 10.4
IL-8 10.4
Transmembrane protein 98 9.8
CD182 9.8
Miner2 9.6
GRO-gamma 9.6
CXCR1 9.5
GCP-2 9.4
CCDC43 9.4
ZNF587 9.4
RAB3IL1 9.4
TNFR1B 9.4
C14orf43 9.4
Tripartite motif-containing 32 9.4
FIBCD1 protein 9.4
WBSCR28 9.4
TNFA protein 9.4
ADPRTL2 9.4
NF-kappaB repressing factor 9.4
ZNF511 9.4
ANGPT3 9.4
Neutrophil protein 9.4
MOBKL2C 9.4
zinc finger protein 583 9.4
ANG-5 9.4
TMED1 9.4
IKBB 9.4
GCP-1 9.4
NAP-4 9.4
CXCL3 9.3
CXCL6 9.3
IL8RA 9.3
PF4V1 9.1
GTP binding protein overexpressed in skeletal muscle 9.1
hNRP 9.1
SLC16A8 9.0
granulocyte chemotactic protein-2 8.8
Homeobox B7 8.8
platelet-derived growth factor alpha polypeptide 8.8
Chemokine (C-C motif) ligand 21 8.8
fucosyltransferase 11 8.8
CCDC63 8.8
galactosidase, beta 1 8.8
NOD5 8.8
TUBAL3 8.8
PAGE5 8.8
Leukotriene B4 receptor 8.8
Repetin 8.8
IL10 protein 8.8
TMOD4 8.8
ZNF84 8.8
ninjurin2 8.8
MAFF protein 8.8
IQCA 8.8
leukocyte membrane antigen 8.8
CLRN3 8.8
IL17RE 8.8
KIAA0053 8.8
zinc finger RNA binding protein 8.8
more...
Disease
GBD2 10.4
inborn aminoaciduria 10.4
Neutrophilic urticaria 10.4
Duodenal Crohn's disease 8.8
Isolated myocarditis 8.8
Retention hyperkeratosis 8.8
urinary bladder disorder 8.8
Staphylococcus aureus toxic shock syndrome 8.4
APSM 8.4
Male accessory gland infection 8.4
Mycoplasma arthritis 8.4
Bronchopulmonary disease 8.4
Primary hypercholesterolemia 8.4
Moraxella catarrhalis infection 8.4
Samter's syndrome 8.1
Canine elbow dysplasia 8.1
Heaves 7.8
Bronchial infection 7.8
SLE arthritis 7.6
Myeloproliferation 7.6
Genitourinary infection 7.6
postperfusion syndrome 7.4
prostate nodule 7.4
MIP 7.3
Fibrosing colonopathy 7.2
ASD2 7.2
Adenosquamous cell carcinoma 7.2
Bacterial gastroenteritis 7.2
Gastric infection 7.2
rhinovirus infection 7.1
Bacillus cereus infection 7.1
Moraxella infection 7.1
Chronic otitis media with effusion 6.9
Diarrhea-associated hemolytic uremic syndrome 6.9
Neutrophil dysfunction 6.9
Renal vasculitis 6.8
DSCR 6.8
Eosinophilic bronchitis 6.8
Squamous Cell Cancer 6.8
Paragonimus westermani infection 6.8
CCL 6.8
LAD2 6.7
Enteric redmouth disease 6.7
essential thrombocytopenia 6.7
Erythema toxicum neonatorum 6.7
Neonatal necrotizing enterocolitis 6.6
Folliculitis decalvans 6.6
Sheep scab 6.6
Biliary tract infection 6.6
Cytokine storm 6.5
Viral Hemorrhagic Septicemia 6.5
sinobronchial syndrome 6.4
Free plasma hemoglobin 6.4
phagocytic dysfunction 6.4
Avian Disease 6.4
Chronic idiopathic neutropenia 6.4
Left main coronary artery disease 6.4
Campbell de Morgan spots 6.3
Vaccinia virus infection 6.3
Stenotrophomonas maltophilia infection 6.3
NALD 6.3
AGEP 6.2
IMD1 6.2
Erythema nodosum leprosum 6.2
Intrauterine infection 6.2
onychorrhexis 6.1
Uterine infection 6.1
ALS5 6.1
Stromal keratitis 6.1
necatoriasis 6.1
Direct infection 6.1
Progression of prostate cancer 6.1
Hemorrhagic septicemia 6.0
Autoimmune inner ear disease 6.0
MYP3 6.0
Ocular surface disease 6.0
mansonelliasis 5.9
Neonatal sepsis 5.9
Acute gouty arthritis 5.9
Tuberculous osteomyelitis 5.8
more...
Symptom
Ear swelling 6.0
Lung hyperinflation 5.6
sinus pain 5.5
itchy nose 5.4
Organ failure 5.4
UTI symptoms 5.4
sinus headache 5.3
Beau's lines 4.7
skin irritant 4.4
Scratch 4.3
labored breathing 3.7
localized edema 3.6
BHS 3.6
nerve pain 3.6
Acute urinary retention 3.4
respiratory distress 3.4
skin irritation 3.3
nasal discharge 3.1
skin damage 3.1
dry eye 3.1
Severe pain 3.1
hyperoxia 2.9
cachexia 2.8
catarrh 2.8
bladder pain 2.8
microbial colonization 2.7
disturbed balance 2.6
Respiratory symptoms 2.5
ACHE 2.5
postnasal drip 2.4
athetosis 2.3
intestinal bleeding 2.3
rigors 2.3
wheezing 2.2
sneezing 2.1
limb pain 2.0
chronic cough 2.0
arthralgia 2.0
diarrhea 2.0
hot flashes 1.9
chills 1.9
loss of taste 1.8
exertional angina 1.8
nasal congestion 1.8
erythema 1.8
decreased appetite 1.8
pelvic pain 1.7
Involuntary Movement 1.7
fever of unknown origin 1.7
breakthrough pain 1.7
HSA 1.6
Spots 1.6
tenesmus 1.5
stomach pain 1.4
twitching 1.4
acute stress 1.4
nipple discharge 1.4
sciatica 1.4
Hudson 1.3
hyperemesis gravidarum 1.3
nipple discharge 1.3
Anoxia 1.3
rhinorrhea 1.2
overweight 1.2
Gastrointestinal symptoms 1.2
halitosis 1.2
persistent cough 1.1
tachypnea 1.1
rales 1.1
exhaustion 1.0
cough 1.0
drooling 1.0
partial seizure 1.0
hypothermia 0.9
myalgia 0.9
chronic back pain 0.8
chest tightness 0.8
bone pain 0.8
anorexia 0.7
splenomegaly 0.7
more...
Drug
Chiron-Behring 10.4
Gepirone hydrochloride 9.4
C16H15NO4 8.8
Cantuzumab mertansine 8.8
Emadine 8.8
Irsogladine maleate 8.6
Quazinone 8.4
CEPR 8.1
N-Formylmethionine 8.1
Carbocysteine 7.8
Lexatumumab 7.8
IL-1ra 7.8
Bindarit 7.4
Lucinactant 7.4
IL-11 7.3
Tacalcitol 7.2
Repetin 7.2
Mapatumumab 7.1
Capsicum oleoresin 7.1
Emedastine difumarate 7.1
Lexipafant 7.1
Patanol 6.9
Apafant 6.9
Piclamilast 6.9
Piclamilast 6.9
Ecabet sodium 6.9
Sivelestat sodium hydrate 6.8
Psyllium husk 6.8
Sivelestat 6.8
CCL 6.7
CXN 6.7
Polaprezinc 6.4
Ulinastatin 6.4
Fluticasone propionate 6.4
Platelet concentrate 6.3
MEDI-524 6.3
G-CSF 6.2
Indiplon 6.2
E5564 6.2
Valrubicin 6.1
Cilomilast 6.0
Rebamipide 6.0
Dextran sulfate sodium 5.9
1,8-Cineole 5.9
IL-2 5.8
Betamethasone valerate 5.7
Tepoxalin 5.7
Crotonaldehyde 5.7
Solifenacin succinate 5.6
Epinastine 5.6
Tulobuterol 5.5
Sodium propionate 5.5
Ebastine 5.4
Gonal-F 5.4
Miglustat 5.3
Budesonide 5.3
CSF 5.3
Prulifloxacin 5.3
Proleukin 5.3
Tariquidar 5.3
Olopatadine hydrochloride 5.3
IFN-gamma 5.2
Survanta 5.2
Anakinra 5.2
Marimastat 5.2
Epostane 5.2
Lonafarnib 5.2
Gonal-F 5.2
Ilomastat 5.1
Adapalene 5.1
Alefacept 5.1
Stelazine 5.1
Imiquimod 5.0
Rifaximin 5.0
Altrenogest 5.0
Travoprost 5.0
Valdecoxib 4.9
IFN-beta 4.8
Orthoclone OKT3 4.8
Benzofuran 4.8
more...
Enzyme
MIP 7.3
histolysain 6.9
C5a peptidase 6.1
fragilysin 5.7
neutrophil collagenase 5.6
neutrophil elastase 5.6
IKK 5.6
MMP-3 5.4
proteinase-3 5.3
Der p 1 5.3
matrix metalloproteinase 10 5.3
Lys-gingipain 5.2
tryptase 5.2
pseudolysin 5.2
HY2 5.1
TSP-1 5.1
glycoprotease 5.0
ECH 5.0
ScpA 5.0
granzyme K 5.0
asparaginyl-tRNA synthetase 4.9
RGP 4.9
ribulose 5-phosphate 3-epimerase 4.9
matrix metalloproteinase 9 4.8
dihydrodipicolinate reductase 4.8
acylglycerol kinase 4.7
sphingomyelinase D 4.7
mitogen-activated protein kinase 4.6
BAL 4.6
elastase 4.6
interstitial collagenase 4.6
TACE 4.6
GP-I 4.5
cathepsin F 4.4
D-dopachrome tautomerase 4.4
caspase-1 4.3
MHCK 4.3
caspase-4 4.3
serralysin 4.2
caspase-4 4.2
lysophospholipase D 4.2
caspase-5 4.2
MMP 4.1
threonine synthase 4.1
collagenase 4.1
AGT 4.1
adamalysin 4.1
p80 4.1
jararhagin 4.1
NADPH:quinone oxidoreductase 4.1
arylsulfate sulfotransferase 4.0
prostaglandin F synthase 4.0
GPI-specific phospholipase C 4.0
KLK7 3.9
CYP8B1 3.9
MAP 3.9
caspase-5 3.9
HK2 3.9
nicotinamide N-methyltransferase 3.8
indoleamine 2,3-dioxygenase 3.8
GAS 3.8
coagulation factor VIIa 3.8
hydroxyprostaglandin dehydrogenase 3.8
p100 3.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.7
PIP kinase 3.7
alpha-isopropylmalate synthase 3.7
20beta-hydroxysteroid dehydrogenase 3.7
myosin light chain kinase 3.7
heme oxygenase 3.7
MEK 3.6
pantetheinase 3.6
ribose-5-phosphate isomerase 3.6
granzyme B 3.6
NADPH oxidase 3.5
matrix metalloproteinase 2 3.5
peptidylarginine deiminase 3.5
DSR 3.5
NADPH oxidase 3.5
cathepsin H 3.5
more...
Compound
Damascenine 10.4
2-(2,5-dimethoxyphenyl)acetamide 10.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
Interferon gamma-1b 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
C16H15NO4 9.4
Stepharine 8.8
C16H26O 8.4
Rhododendrin 8.4
C16H26O6 8.4
C14H10O2 8.4
C16H17NO2 8.4
C16H15NO4 8.4
Kitasamycin 8.1
C16H15NO4 8.1
C11H12O4 8.1
C16H15NO4 8.1
C16H15NO4 7.8
Xanthotoxol 7.8
Dimethyl itaconate 7.8
Arborinine 7.8
Hydrangenol 7.6
Eudesmin 7.6
Dimethyl phosphate 7.6
Allyl methyl disulfide 7.4
Flumidin 7.4
Budlein A 7.2
Avarone 7.2
9(S)-HODE 7.2
Columbianetin 7.2
PPBP 7.2
Taraxasterol 7.1
Plantamajoside 7.1
Senegenin 7.1
Tubeimoside I 7.1
Casuarinin 7.1
5,11-dimethyl-6H-pyrido[4,3-b]carbazole 7.1
Fluticasone 7.0
C13H12N2O2 6.9
Miltirone 6.9
Budlein A 6.9
Chebulagic acid 6.8
Sulconazole 6.8
Chebulagic acid 6.8
Dhurrin 6.8
C16H16N2 6.8
Fluticasone 6.7
FMLP 6.6
Genkwanin 6.6
Eriochrome Cyanine R 6.6
Bornyl acetate 6.6
Hepoxilin A3 6.6
Bornyl acetate 6.6
Securinine 6.5
ethanesulfonamide 6.5
Pinane 6.5
more...