Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P10145 (IL-8)
23,849 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IL-8 23849
IL-6 8897
cytokine 7165
TNF 4070
IL-10 3306
tumor necrosis factor 2664
chemokine 2649
TNF-alpha 2183
lipopolysaccharide 1767
Mol 1566
MCP-1 1536
Sep 1473
IL-4 1464
IL-1 1406
IFN 1336
IL-2 1234
LPS 1178
RANTES 1168
Cytokine 1104
p38 1027
interferon 980
TLR4 941
CXCL10 846
IFN-gamma 835
IL-17 804
CCL2 801
IL-1 beta 776
GM-CSF 775
tumor necrosis factor alpha 727
p65 705
ICAM-1 701
THP 683
VEGF 665
MAPK 650
TLR2 649
vascular endothelial growth factor 645
IL6 625
interleukin-6 607
IL-5 599
MIP 588
CXCL1 588
IL-13 586
CXCR1 542
CXCR2 515
C-reactive protein 491
IL-18 471
ERK1 459
collagen 456
ERK 442
CD4 417
granulocyte 414
JNK 413
interferon-gamma 405
CD14 400
monocyte chemoattractant protein-1 399
gut 381
vascular cell adhesion molecule-1 355
myeloperoxidase 350
COX-2 346
adhesion molecule 345
inducible nitric oxide synthase 344
AP-1 339
MMP-9 339
granulocyte-macrophage colony-stimulating factor 336
interleukin 6 311
E-selectin 305
G-CSF 305
IL-15 298
monocyte chemotactic protein 296
monocyte chemoattractant protein 292
CD11b 288
IL-1 alpha 288
GRO 287
TGF-beta 287
macrophage colony-stimulating factor 272
matrix metalloproteinase 268
MIP-1alpha 268
CXC chemokine 267
CCL20 263
Pseudomonas 260
more...
Disease
cancer 1887
tumor 1628
asthma 636
MIP 588
sepsis 545
sepsis 504
rheumatoid arthritis 502
chronic obstructive pulmonary disease 481
atherosclerosis 383
breast cancer 355
infectious diseases 348
tumor growth 341
HIV 337
cystic fibrosis 316
virus infection 306
psoriasis 290
tumor progression 289
melanoma 275
carcinoma 272
inflammatory bowel disease 260
arthritis 255
periodontitis 250
osteoarthritis 249
diabetes 246
obesity 245
pneumonia 229
bacterial infection 229
Infection 224
carcinogenesis 202
tumorigenesis 201
ischemia 194
colitis 193
gastric cancer 188
tuberculosis 184
Mycobacterium 184
adenocarcinoma 182
colorectal cancer 181
influenza 172
metastases 167
ulcerative colitis 166
leukemia 159
mastitis 155
Crohn's disease 155
lung cancer 154
lung disease 154
hepatocellular carcinoma 146
plaque 145
immunodeficiency 136
GSH 133
squamous cell carcinoma 132
prostate cancer 131
pertussis 128
cardiovascular disease 128
Blocking 123
gastritis 121
atopic dermatitis 119
depression 114
Alzheimer's disease 114
ovarian cancer 111
skin disease 106
dermatitis 105
CCL 104
systemic lupus erythematosus 100
hypertension 100
colon cancer 97
HGF 97
glioma 96
uterus 95
periodontal disease 94
pancreatic cancer 93
type 2 diabetes 92
SARS 92
multiple sclerosis 92
COPD 91
stroke 91
Chlamydia 89
tumor angiogenesis 88
AIDS 88
cold 86
AGS 85
more...
Symptom
pain 179
diarrhea 167
respiratory distress 153
anesthesia 68
fatigue 52
overweight 46
cough 36
erythema 34
cachexia 30
hyperoxia 29
dyspnea 27
hypothermia 24
seizures 24
headache 23
exhaustion 21
arthralgia 21
angina 20
dry eye 17
anorexia 17
collapse 17
wheezing 17
skin irritation 16
vomiting 16
discomfort 13
discomfort 13
chills 12
abdominal pain 12
splenomegaly 12
starvation 12
low back pain 11
skin damage 10
pelvic pain 10
acidity 9
myalgia 9
acute stress 9
nausea 9
nasal discharge 9
analgesia 8
sleepiness 8
back pain 7
flushing 7
weakness 7
HSA 7
Scratch 6
Ill 6
sneezing 6
chronic cough 6
lethargy 5
fever of unknown origin 5
microbial colonization 5
constipation 5
hypercapnia 5
ataxia 4
thinning 4
hepatosplenomegaly 4
spasm 4
functional recovery 4
rhinorrhea 4
bone pain 4
twitching 4
agitation 4
tremor 4
tachypnea 4
sore throat 3
insomnia 3
sciatica 3
nasal congestion 3
colic 3
Ear swelling 3
Wind 3
decreased appetite 3
intestinal bleeding 3
rigors 3
skin irritant 3
paresis 3
hot flashes 3
chest pain 3
labored breathing 2
hepatomegaly 2
Hudson 2
more...
Drug
IL-2 1236
CSF 928
IFN-gamma 822
Dermatol 380
G-CSF 295
IL-1ra 226
ROS 202
IL-11 129
CCL 104
MAP 96
lysine 84
Asthma 79
IFN-beta 64
Bifidobacterium 55
Histamine 42
Monit 42
Cardiovasc 40
ROC 36
p75 34
ascorbate 29
vitamin E 27
uPA 25
Dial 25
ZnO 24
CAM 23
Albumin 20
TAK 19
Budesonide 19
Lovastatin 19
Ethanol 19
Leaf 18
MRC 18
Gel 17
TiO2 16
ampicillin 14
ICI 13
Simvastatin 13
Imiquimod 13
EPA 13
CTX 13
GEO 13
Indomethacin 12
Nephron 12
lactose 12
ABC 12
Heme 12
TTC 12
Azithromycin 11
Activin 10
Asn 10
KGF 10
Kenyan 10
ALA 9
NAG 9
Infliximab 9
Infliximab 9
CTX 8
CoCl2 8
CTX 8
niacin 8
Silica 8
CoCl2 8
Vitamin E 8
Nephron 8
NBT 8
Glycyrrhiza 8
ADM 8
Ulinastatin 7
Rebamipide 7
balanced salt solution 7
Tocilizumab 7
Anakinra 7
PTH 7
Biopolymers 7
Allergen 7
Aprotinin 7
Fluticasone propionate 7
Theophylline 7
Omalizumab 6
TAC 6
more...
Enzyme
mitogen-activated protein kinase 1763
ERK 697
MIP 589
peroxidase 384
superoxide dismutase 314
luciferase 293
protein kinase 253
protein kinase C 243
collagenase 240
catalase 215
reverse transcriptase 201
focal adhesion kinase 191
caspase-3 182
IKK 177
MEK 167
elastase 165
thrombin 155
lactate dehydrogenase 154
lysozyme 150
neutrophil elastase 149
trypsin 129
glutathione peroxidase 113
MMP-3 111
alkaline phosphatase 99
proteasome 98
NADPH oxidase 93
caspase-1 93
NADPH oxidase 89
MAP 81
alanine aminotransferase 80
phospholipase C 80
aspartate aminotransferase 79
tryptase 76
phosphatidylinositol 3-kinase 74
RNA polymerase 73
phospholipase A2 58
acid phosphatase 58
creatine kinase 56
APC 56
MMP 56
NO synthase 56
urokinase-type plasminogen activator 55
glutathione S-transferase 50
matrix metalloproteinase 9 47
phosphodiesterase 47
RNase 47
RNase 47
ATPase 47
calcineurin 47
PARP 45
transcriptase 44
caspase-8 42
AMP-activated protein kinase 42
phosphoinositide 3-kinase 40
heme oxygenase 40
glutathione reductase 40
BAL 36
caspase-9 34
NQO1 34
glyceraldehyde-3-phosphate dehydrogenase 33
urease 32
AMPK 31
granzyme B 29
urease 29
GSK 28
lipoxygenase 26
AMPK 26
myosin light chain kinase 26
NOS 25
ECH 25
AST 25
tissue plasminogen activator 24
arginase 23
CD13 23
histone acetyltransferase 22
TSP-1 22
beta-galactosidase 21
hyaluronidase 21
neuraminidase 20
matrix metalloproteinase 2 20
more...
Compound
TNF 4070
Dec 1606
DNA 1260
Clin 1107
oxygen 1055
THP 683
THP 683
calcium 639
nitric oxide 393
acetate 364
glucose 361
water 317
sodium 304
sulfate 218
cysteine 214
tyrosine 208
PGE2 194
PMA 186
MTT 186
Phe 182
MDA 182
PMA 178
PGE 176
arginine 175
serine 161
cAMP 158
hydrogen 155
leucine 149
phosphate 148
ATP 146
GSH 137
GSH 137
ethanol 128
iron 123
lysine 115
zinc 114
nitrogen 102
galactose 100
creatinine 96
H2O2 93
vitamin D 92
MEK 91
methionine 89
NH2 86
MAP 86
FMLP 84
Dexamethasone 80
urea 79
N-acetylcysteine 76
alanine 70
CAT 63
CAT 62
CAT 62
nickel 61
SDS 61
retinoic acid 58
bromide 58
hyaluronic acid 58
CO2 57
titanium 57
Curcumin 55
threonine 55
salt 54
copper 50
silver 49
Cardiol 49
AMP 49
iodine 48
pyrrolidine 48
PEG 47
His 46
ASA 45
pyrrolidine 45
neopterin 45
Resveratrol 44
nitrate 43
Histamine 42
glutamine 42
PAM 41
tryptophan 41
more...