Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P10145 (
IL-8
)
23,849
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
IL-8
23849
IL-6
8897
cytokine
7165
TNF
4070
IL-10
3306
tumor necrosis factor
2664
chemokine
2649
TNF-alpha
2183
lipopolysaccharide
1767
Mol
1566
MCP-1
1536
Sep
1473
IL-4
1464
IL-1
1406
IFN
1336
IL-2
1234
LPS
1178
RANTES
1168
Cytokine
1104
p38
1027
interferon
980
TLR4
941
CXCL10
846
IFN-gamma
835
IL-17
804
CCL2
801
IL-1 beta
776
GM-CSF
775
tumor necrosis factor alpha
727
p65
705
ICAM-1
701
THP
683
VEGF
665
MAPK
650
TLR2
649
vascular endothelial growth factor
645
IL6
625
interleukin-6
607
IL-5
599
MIP
588
CXCL1
588
IL-13
586
CXCR1
542
CXCR2
515
C-reactive protein
491
IL-18
471
ERK1
459
collagen
456
ERK
442
CD4
417
granulocyte
414
JNK
413
interferon-gamma
405
CD14
400
monocyte chemoattractant protein-1
399
gut
381
vascular cell adhesion molecule-1
355
myeloperoxidase
350
COX-2
346
adhesion molecule
345
inducible nitric oxide synthase
344
AP-1
339
MMP-9
339
granulocyte-macrophage colony-stimulating factor
336
interleukin 6
311
E-selectin
305
G-CSF
305
IL-15
298
monocyte chemotactic protein
296
monocyte chemoattractant protein
292
CD11b
288
IL-1 alpha
288
GRO
287
TGF-beta
287
macrophage colony-stimulating factor
272
matrix metalloproteinase
268
MIP-1alpha
268
CXC chemokine
267
CCL20
263
Pseudomonas
260
more...
Disease
cancer
1887
tumor
1628
asthma
636
MIP
588
sepsis
545
sepsis
504
rheumatoid arthritis
502
chronic obstructive pulmonary disease
481
atherosclerosis
383
breast cancer
355
infectious diseases
348
tumor growth
341
HIV
337
cystic fibrosis
316
virus infection
306
psoriasis
290
tumor progression
289
melanoma
275
carcinoma
272
inflammatory bowel disease
260
arthritis
255
periodontitis
250
osteoarthritis
249
diabetes
246
obesity
245
pneumonia
229
bacterial infection
229
Infection
224
carcinogenesis
202
tumorigenesis
201
ischemia
194
colitis
193
gastric cancer
188
tuberculosis
184
Mycobacterium
184
adenocarcinoma
182
colorectal cancer
181
influenza
172
metastases
167
ulcerative colitis
166
leukemia
159
mastitis
155
Crohn's disease
155
lung cancer
154
lung disease
154
hepatocellular carcinoma
146
plaque
145
immunodeficiency
136
GSH
133
squamous cell carcinoma
132
prostate cancer
131
pertussis
128
cardiovascular disease
128
Blocking
123
gastritis
121
atopic dermatitis
119
depression
114
Alzheimer's disease
114
ovarian cancer
111
skin disease
106
dermatitis
105
CCL
104
systemic lupus erythematosus
100
hypertension
100
colon cancer
97
HGF
97
glioma
96
uterus
95
periodontal disease
94
pancreatic cancer
93
type 2 diabetes
92
SARS
92
multiple sclerosis
92
COPD
91
stroke
91
Chlamydia
89
tumor angiogenesis
88
AIDS
88
cold
86
AGS
85
more...
Symptom
pain
179
diarrhea
167
respiratory distress
153
anesthesia
68
fatigue
52
overweight
46
cough
36
erythema
34
cachexia
30
hyperoxia
29
dyspnea
27
hypothermia
24
seizures
24
headache
23
exhaustion
21
arthralgia
21
angina
20
dry eye
17
anorexia
17
collapse
17
wheezing
17
skin irritation
16
vomiting
16
discomfort
13
discomfort
13
chills
12
abdominal pain
12
splenomegaly
12
starvation
12
low back pain
11
skin damage
10
pelvic pain
10
acidity
9
myalgia
9
acute stress
9
nausea
9
nasal discharge
9
analgesia
8
sleepiness
8
back pain
7
flushing
7
weakness
7
HSA
7
Scratch
6
Ill
6
sneezing
6
chronic cough
6
lethargy
5
fever of unknown origin
5
microbial colonization
5
constipation
5
hypercapnia
5
ataxia
4
thinning
4
hepatosplenomegaly
4
spasm
4
functional recovery
4
rhinorrhea
4
bone pain
4
twitching
4
agitation
4
tremor
4
tachypnea
4
sore throat
3
insomnia
3
sciatica
3
nasal congestion
3
colic
3
Ear swelling
3
Wind
3
decreased appetite
3
intestinal bleeding
3
rigors
3
skin irritant
3
paresis
3
hot flashes
3
chest pain
3
labored breathing
2
hepatomegaly
2
Hudson
2
more...
Drug
IL-2
1236
CSF
928
IFN-gamma
822
Dermatol
380
G-CSF
295
IL-1ra
226
ROS
202
IL-11
129
CCL
104
MAP
96
lysine
84
Asthma
79
IFN-beta
64
Bifidobacterium
55
Histamine
42
Monit
42
Cardiovasc
40
ROC
36
p75
34
ascorbate
29
vitamin E
27
uPA
25
Dial
25
ZnO
24
CAM
23
Albumin
20
TAK
19
Budesonide
19
Lovastatin
19
Ethanol
19
Leaf
18
MRC
18
Gel
17
TiO2
16
ampicillin
14
ICI
13
Simvastatin
13
Imiquimod
13
EPA
13
CTX
13
GEO
13
Indomethacin
12
Nephron
12
lactose
12
ABC
12
Heme
12
TTC
12
Azithromycin
11
Activin
10
Asn
10
KGF
10
Kenyan
10
ALA
9
NAG
9
Infliximab
9
Infliximab
9
CTX
8
CoCl2
8
CTX
8
niacin
8
Silica
8
CoCl2
8
Vitamin E
8
Nephron
8
NBT
8
Glycyrrhiza
8
ADM
8
Ulinastatin
7
Rebamipide
7
balanced salt solution
7
Tocilizumab
7
Anakinra
7
PTH
7
Biopolymers
7
Allergen
7
Aprotinin
7
Fluticasone propionate
7
Theophylline
7
Omalizumab
6
TAC
6
more...
Enzyme
mitogen-activated protein kinase
1763
ERK
697
MIP
589
peroxidase
384
superoxide dismutase
314
luciferase
293
protein kinase
253
protein kinase C
243
collagenase
240
catalase
215
reverse transcriptase
201
focal adhesion kinase
191
caspase-3
182
IKK
177
MEK
167
elastase
165
thrombin
155
lactate dehydrogenase
154
lysozyme
150
neutrophil elastase
149
trypsin
129
glutathione peroxidase
113
MMP-3
111
alkaline phosphatase
99
proteasome
98
NADPH oxidase
93
caspase-1
93
NADPH oxidase
89
MAP
81
alanine aminotransferase
80
phospholipase C
80
aspartate aminotransferase
79
tryptase
76
phosphatidylinositol 3-kinase
74
RNA polymerase
73
phospholipase A2
58
acid phosphatase
58
creatine kinase
56
APC
56
MMP
56
NO synthase
56
urokinase-type plasminogen activator
55
glutathione S-transferase
50
matrix metalloproteinase 9
47
phosphodiesterase
47
RNase
47
RNase
47
ATPase
47
calcineurin
47
PARP
45
transcriptase
44
caspase-8
42
AMP-activated protein kinase
42
phosphoinositide 3-kinase
40
heme oxygenase
40
glutathione reductase
40
BAL
36
caspase-9
34
NQO1
34
glyceraldehyde-3-phosphate dehydrogenase
33
urease
32
AMPK
31
granzyme B
29
urease
29
GSK
28
lipoxygenase
26
AMPK
26
myosin light chain kinase
26
NOS
25
ECH
25
AST
25
tissue plasminogen activator
24
arginase
23
CD13
23
histone acetyltransferase
22
TSP-1
22
beta-galactosidase
21
hyaluronidase
21
neuraminidase
20
matrix metalloproteinase 2
20
more...
Compound
TNF
4070
Dec
1606
DNA
1260
Clin
1107
oxygen
1055
THP
683
THP
683
calcium
639
nitric oxide
393
acetate
364
glucose
361
water
317
sodium
304
sulfate
218
cysteine
214
tyrosine
208
PGE2
194
PMA
186
MTT
186
Phe
182
MDA
182
PMA
178
PGE
176
arginine
175
serine
161
cAMP
158
hydrogen
155
leucine
149
phosphate
148
ATP
146
GSH
137
GSH
137
ethanol
128
iron
123
lysine
115
zinc
114
nitrogen
102
galactose
100
creatinine
96
H2O2
93
vitamin D
92
MEK
91
methionine
89
NH2
86
MAP
86
FMLP
84
Dexamethasone
80
urea
79
N-acetylcysteine
76
alanine
70
CAT
63
CAT
62
CAT
62
nickel
61
SDS
61
retinoic acid
58
bromide
58
hyaluronic acid
58
CO2
57
titanium
57
Curcumin
55
threonine
55
salt
54
copper
50
silver
49
Cardiol
49
AMP
49
iodine
48
pyrrolidine
48
PEG
47
His
46
ASA
45
pyrrolidine
45
neopterin
45
Resveratrol
44
nitrate
43
Histamine
42
glutamine
42
PAM
41
tryptophan
41
more...