Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P10145 (
IL-8
)
23,849
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
IL-8
23849
IL-6
8897
cytokine
7165
TNF
4070
IL-10
3306
tumor necrosis factor
2664
chemokine
2649
TNF-alpha
2183
lipopolysaccharide
1767
Mol
1566
MCP-1
1536
Sep
1473
IL-4
1464
IL-1
1406
IFN
1336
IL-2
1234
LPS
1178
RANTES
1168
Cytokine
1104
p38
1027
interferon
980
TLR4
941
CXCL10
846
IFN-gamma
835
IL-17
804
CCL2
801
IL-1 beta
776
GM-CSF
775
tumor necrosis factor alpha
727
p65
705
ICAM-1
701
THP
683
VEGF
665
MAPK
650
TLR2
649
vascular endothelial growth factor
645
IL6
625
interleukin-6
607
IL-5
599
CXCL1
588
more...
Disease
cancer
1887
tumor
1628
asthma
636
MIP
588
sepsis
545
sepsis
504
rheumatoid arthritis
502
chronic obstructive pulmonary disease
481
atherosclerosis
383
breast cancer
355
infectious diseases
348
tumor growth
341
HIV
337
cystic fibrosis
316
virus infection
306
psoriasis
290
tumor progression
289
melanoma
275
carcinoma
272
inflammatory bowel disease
260
arthritis
255
periodontitis
250
osteoarthritis
249
diabetes
246
obesity
245
bacterial infection
229
pneumonia
229
Infection
224
carcinogenesis
202
tumorigenesis
201
ischemia
194
colitis
193
gastric cancer
188
tuberculosis
184
Mycobacterium
184
adenocarcinoma
182
colorectal cancer
181
influenza
172
metastases
167
ulcerative colitis
166
more...
Symptom
pain
179
diarrhea
167
respiratory distress
153
anesthesia
68
fatigue
52
overweight
46
cough
36
erythema
34
cachexia
30
hyperoxia
29
dyspnea
27
seizures
24
hypothermia
24
headache
23
exhaustion
21
arthralgia
21
angina
20
anorexia
17
collapse
17
wheezing
17
dry eye
17
skin irritation
16
vomiting
16
discomfort
13
discomfort
13
chills
12
starvation
12
splenomegaly
12
abdominal pain
12
low back pain
11
skin damage
10
pelvic pain
10
myalgia
9
acidity
9
nausea
9
acute stress
9
nasal discharge
9
analgesia
8
sleepiness
8
flushing
7
more...
Drug
IL-2
1236
CSF
928
IFN-gamma
822
Dermatol
380
G-CSF
295
IL-1ra
226
ROS
202
IL-11
129
CCL
104
MAP
96
lysine
84
Asthma
79
IFN-beta
64
Bifidobacterium
55
Histamine
42
Monit
42
Cardiovasc
40
ROC
36
p75
34
ascorbate
29
vitamin E
27
Dial
25
uPA
25
ZnO
24
CAM
23
Albumin
20
Ethanol
19
Lovastatin
19
TAK
19
Budesonide
19
Leaf
18
MRC
18
Gel
17
TiO2
16
ampicillin
14
Imiquimod
13
EPA
13
Simvastatin
13
CTX
13
GEO
13
more...
Enzyme
mitogen-activated protein kinase
1763
ERK
697
MIP
589
peroxidase
384
superoxide dismutase
314
luciferase
293
protein kinase
253
protein kinase C
243
collagenase
240
catalase
215
reverse transcriptase
201
focal adhesion kinase
191
caspase-3
182
IKK
177
MEK
167
elastase
165
thrombin
155
lactate dehydrogenase
154
lysozyme
150
neutrophil elastase
149
trypsin
129
glutathione peroxidase
113
MMP-3
111
alkaline phosphatase
99
proteasome
98
NADPH oxidase
93
caspase-1
93
NADPH oxidase
89
MAP
81
alanine aminotransferase
80
phospholipase C
80
aspartate aminotransferase
79
tryptase
76
phosphatidylinositol 3-kinase
74
RNA polymerase
73
acid phosphatase
58
phospholipase A2
58
APC
56
NO synthase
56
MMP
56
more...
Compound
TNF
4070
Dec
1606
DNA
1260
Clin
1107
oxygen
1055
THP
683
THP
683
calcium
639
nitric oxide
393
acetate
364
glucose
361
water
317
sodium
304
sulfate
218
cysteine
214
tyrosine
208
PGE2
194
PMA
186
MTT
186
MDA
182
Phe
182
PMA
178
PGE
176
arginine
175
serine
161
cAMP
158
hydrogen
155
leucine
149
phosphate
148
ATP
146
GSH
137
GSH
137
ethanol
128
iron
123
lysine
115
zinc
114
nitrogen
102
galactose
100
creatinine
96
H2O2
93
more...