Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P08908 (
5-HT1A
)
5,574
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
5-HT1A
5574
5-HT1B
868
5-hydroxytryptamine
849
5-HT2A
834
HT3
486
5-HT receptor
468
Sep
387
5-HT2 receptor
369
5-HT2C
292
5-HT1D
270
5-HT7
226
5-HT3 receptor
226
CA1
163
serotonin receptor
148
5-HT4
141
Mol
129
serotonin transporter
120
GABA
114
adenylate cyclase
110
prolactin
107
GTP
95
CA3
81
5-HT4 receptor
76
ICS
75
dopamine D2 receptor
75
5-HT6
74
adenylyl cyclase
73
5-HT2B
73
tryptophan hydroxylase
71
5HT1A
60
Pol
59
SCH
57
NMDA receptor
57
beta-endorphin
56
ACTH
54
olfactory
54
LSD
52
brain-derived neurotrophic factor
51
AMP
49
cage
47
more...
Disease
depression
526
schizophrenia
213
major depressive disorder
170
anxiety disorders
116
aggression
113
pertussis
85
ICS
75
catalepsy
72
Parkinson's disease
72
SCH
57
Alzheimer's disease
56
psychosis
48
panic disorder
48
dyskinesia
45
cognitive impairment
44
suicide
42
obsessive-compulsive disorder
35
hyperphagia
32
migraine
31
cold
30
epilepsy
28
bipolar disorder
26
hypertension
26
mental illness
25
dementia
23
addiction
20
disinhibition
19
panic attacks
19
posttraumatic stress disorder
18
memory impairment
18
cancer
18
alcoholism
17
fits
17
PCP
17
NSD
17
NAME
17
ischemia
15
abnormal involuntary movements
15
hyperglycemia
15
aggressiveness
14
more...
Symptom
hypothermia
180
pain
115
analgesia
46
seizures
45
nausea
32
vomiting
27
tremor
26
anesthesia
24
insomnia
24
headache
24
myoclonus
17
agitation
15
dizziness
14
ataxia
13
anorexia
13
fatigue
11
despair
11
sleepiness
11
diarrhea
11
dystonia
8
nausea and vomiting
8
bradykinesia
7
cough
7
hypercapnia
7
twitching
6
acute stress
6
discomfort
5
discomfort
5
cerebellar ataxia
5
constipation
5
exhaustion
4
lightheadedness
4
Neuropathic pain
3
syncope
3
catatonia
3
muscle rigidity
3
asthenia
3
Decreased activity
3
impaired motor coordination
3
chorea
2
more...
Drug
DHT
61
DHT
61
ICI
52
Portal
48
Cardiovasc
25
Ritanserin
22
Flesinoxan
21
Clonidine
18
Nephron
17
PCP
17
Mirtazapine
13
Scopolamine
13
Flibanserin
12
CTX
10
Ethanol
10
caffeine
9
Forskolin
9
Atropine
7
Domperidone
7
Duloxetine
6
nitroglycerin
6
Reserpine
6
SR 57746A
6
Mutagen
5
CDP
5
Buspar
4
Renzapride
4
Apomorphine
4
Xaliproden
4
Dermatol
4
Sulpiride
4
Dexfenfluramine
4
Tianeptine
4
Buspar
4
Histamine
3
Ringer's solution
3
Lisuride
3
CSF
3
Atipamezole
3
DMI
3
more...
Enzyme
adenylate cyclase
113
tryptophan hydroxylase
72
monoamine oxidase
66
protein kinase
45
protein kinase C
35
mitogen-activated protein kinase
31
ERK
26
renin
24
phospholipase C
23
DMT
19
PCP
17
acetylcholinesterase
16
phosphodiesterase
16
tyrosine hydroxylase
16
DOPA decarboxylase
13
PAT
13
ACS
12
cholinesterase
10
NO synthase
10
aromatic L-amino acid decarboxylase
7
GTI
7
guanylate cyclase
7
CYP3A4
6
P-glycoprotein
6
GSK
6
caspase-3
6
luciferase
5
MEK
5
ACE
4
focal adhesion kinase
4
phosphatidylinositol 3-kinase
4
endo-N
4
RNA polymerase
4
CaMKII
4
transcriptase
4
lipoxygenase
3
AMPK
3
ATPase
3
choline acetyltransferase
3
DAT
3
more...
Compound
5-HT
2527
Dec
406
piperazine
332
Neu5Ac
222
noradrenaline
180
5-hydroxytryptophan
165
calcium
153
glutamate
144
Clin
139
Risperidone
124
water
123
Buspirone
118
GABA
114
GABA
114
cAMP
97
GTP
95
ethanol
89
CPP
84
hydroxyindoleacetic acid
77
cyclohexanecarboxamide
71
glucose
70
5-HTP
69
hydroxide
69
NMDA
69
1H-indole
68
5-HTP
67
sodium
67
potassium
67
L-DOPA
61
DHT
61
CPP
61
HCl
60
tryptophan
59
Pindolol
58
tryptophan
56
tryptophan
55
tryptophan
55
LSD
54
dipropyl
53
ACTH
53
more...