Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P08908 (5-HT1A)
5,574 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
5-HT1A 12.5
monoamine oxidase A variant 12.5
5-HT1B 11.6
Freud-1 11.5
BTBD17 11.5
NUDR 11.3
5-HT1D 11.2
5-HT5A 11.2
5-HT7 11.2
GABA-A receptor-associated protein 10.9
RDC4 10.8
5-HT1F 10.8
5-HT2C 10.5
CC2D1B 10.5
regulator of G-protein signalling 9 10.5
5-HT2A 10.5
5-HT2 receptor 10.4
HTR1A 10.3
5-HT receptor 10.3
5-HT6 10.2
5-HT4 10.1
HT3 10.1
S31 10.1
CC2D1A 10.0
5HT1A 9.8
Relaxin 3 9.5
5-HT4 receptor 9.4
5-HT2B 9.4
5-HT3B 9.2
LCAP 9.2
5-HT3 receptor 9.1
5-HT-1A 9.1
DEAF1 9.0
brain glycogen phosphorylase 8.9
Tryptophan hydroxylase 1 8.9
HA7 8.9
HTR3 8.7
serotonin receptor 8.6
ICS 8.6
HTR1F 8.5
TAAR5 8.4
Serotonin receptor 8.4
5-hydroxytryptamine 8.4
5-HT3R 8.3
DOB 8.2
Dopamine D4 receptor 8.2
serotonin receptor 7 8.2
KLF16 8.1
SERT 8.1
HOMER1 8.0
NPSR1 8.0
histamine receptor H1 8.0
tryptophan hydroxylase 7.9
HTR5A 7.8
DMT 7.8
5-HT-2 7.7
SCP-1 7.7
HTR1B 7.7
TPIT 7.7
GRM2 7.7
TRIM32 7.7
SMARCC2 7.6
relaxin 3 7.5
GSK3A 7.5
serotonin transporter 7.5
LSD 7.5
dopamine D2 receptor 7.5
Dopamine D3 receptor 7.4
ligand gated ion channel 7.4
SMARCC1 7.4
HGPS 7.4
HES6 7.4
RGS4 protein 7.4
GALR1 7.3
RGSZ1 7.3
PRX 7.3
GALR2 7.2
CT15 7.2
NSD 7.2
KCTD12 7.2
neuropeptide Y1 receptor 7.2
tryptophan hydroxylase 2 7.2
dopamine receptor D3 7.2
GPR39 7.1
P71 7.1
5-HTTLPR 7.1
galanin receptor 7.1
phosphodiesterase 10A 7.1
MAP2C 7.0
CRYM 7.0
5HT1a 7.0
BAF57 7.0
G protein-linked receptor 7.0
BRL 7.0
SWS1 6.9
plasma membrane monoamine transporter 6.9
TPH2 6.8
DOM 6.8
BAF170 6.8
TRN 6.8
SMARCE1 6.8
VHP 6.8
lyt-10 6.8
DSP-4 6.7
D2 dopamine receptor 6.7
Galphaz 6.7
Tryptophan hydroxylase 6.7
NGD 6.6
neurotransmitter receptor 6.6
HTT 6.6
GAIP 6.6
adenylate cyclase-coupled 6.6
D5 dopamine receptor 6.5
HTR3A 6.5
MAOA 6.5
CT18 6.5
MAPA 6.5
DRw11 6.4
HDS 6.4
mGlu7 6.4
OBX 6.4
GIRK3 6.4
RGS10 6.4
HN2 6.4
CA4 6.4
GPR55 6.3
spn 6.3
TCB 6.3
TPH1 6.3
CRHR1 6.3
K36 6.3
organic cation transporter 3 6.2
NNH 6.2
neuroligin 2 6.2
RGS2 6.2
FGF20 6.2
GIRK1 6.2
Tph 6.2
P55 6.1
dopamine D1 receptor 6.1
neurokinin 1 receptor 6.1
CRF1 6.1
GTP binding protein 6.1
Sperm protein 17 6.1
ALK3 6.1
TREK1 6.1
Dermatopontin 6.0
HES5 6.0
SYP 6.0
INI 6.0
CA2 6.0
SCH 6.0
VMAT2 6.0
MAO-A 5.9
3-phosphoinositide-dependent protein kinase 1 5.9
TRKB 5.9
SLC6A4 5.9
VAMP1 5.9
dopamine D3 receptor 5.9
NF-I 5.9
more...
Disease
Offensive aggression 11.5
Drug-induced dyskinesia 10.9
ICS 7.8
Cocaine use disorder 7.7
Delayed sleep phase syndrome 7.5
Reactive Attachment Disorder 7.5
catalepsy 7.4
NSD 7.2
Bezold 7.1
abnormal involuntary movements 7.1
Morphine dependence 7.0
superficial spreading malignant melanoma 6.9
OBX 6.8
Chronic arthritis 6.7
NNH 6.7
aggressive personality 6.6
psychoactive substance use disorders 6.6
despondency 6.6
hypoactive sexual desire disorder 6.5
FIH 6.3
LDS 6.3
bipolar depression 6.2
psychogenic amnesia 6.2
Nicotine withdrawal 6.1
SWS 6.0
SCH 6.0
fear and anxiety 5.8
panic disorder 5.7
PPP 5.6
dyskinesia 5.6
kleptomania 5.6
DRD 5.6
panic disorder with agoraphobia 5.5
Ovary 5.5
panic attacks 5.5
major depressive disorder 5.5
anxiety disorders 5.4
depressive personality 5.4
premature ejaculation 5.3
BPP 5.3
Stereotypy 5.2
EMD 5.1
induced psychosis 5.1
Estrogen deficiency 5.1
stereotypies 5.1
anxiety state 5.1
HBT 5.0
hyperphagia 4.9
motion sickness 4.8
SCA6 4.8
Ovary 4.8
psychomotor impairment 4.8
Akathisia 4.7
obsessive-compulsive disorder 4.7
GAD 4.6
schizophrenic psychosis 4.6
cocaine addiction 4.6
pertussis 4.6
Cannabis 4.6
parasympathomimetic 4.6
clinical anxiety 4.6
disinhibition 4.5
hallucinosis 4.5
vascular headache 4.5
derealization 4.5
RDS 4.5
aggression 4.5
SME 4.5
IVA 4.4
MIN 4.4
MIN 4.4
major depressive episode 4.3
schizophrenia 4.3
Frey 4.3
anhedonia 4.3
impulse control disorder 4.3
Machado-Joseph disease 4.3
HAM 4.3
sexual dysfunction 4.2
sudden infant death syndrome 4.2
unipolar depression 4.2
emotional stress 4.2
flashbacks 4.2
chronic schizophrenia 4.2
hormone refractory prostate cancer 4.2
tardive dyskinesia 4.2
Intestinal ischemia 4.2
depression 4.1
physical dependence 4.1
PBD 4.1
leukoderma 4.1
SWS 4.1
OFC 4.1
anterograde amnesia 4.0
parasomnia 4.0
Cerebellum 4.0
social stress 4.0
OSX 4.0
cocaine abuse 3.9
perseveration 3.9
mania 3.9
agoraphobia 3.9
somatization disorder 3.9
schizotypal personality disorder 3.8
FFI 3.8
memory impairment 3.8
HPA 3.8
cognitive deficit 3.8
clinical depression 3.8
PCP 3.8
manic episode 3.8
PND 3.8
generalized seizure 3.8
amnesia 3.8
carcinoid syndrome 3.7
HCI 3.7
Opiates 3.7
dysthymia 3.7
psychotic depression 3.6
social phobia 3.6
behavior disorder 3.6
HRS 3.6
olivopontocerebellar atrophy 3.6
sympathomimetic 3.5
bradyarrhythmia 3.5
gastric lesion 3.4
AIN 3.4
HES 3.4
schizoaffective disorder 3.4
hypercortisolemia 3.4
progeria 3.4
migraine 3.4
bipolar disorder 3.4
Sexual dysfunction 3.4
Rett syndrome 3.4
SAD 3.4
MTC 3.4
behavior problem 3.4
ocular hypertension 3.3
excessive drinking 3.3
SPM 3.3
akinesia 3.3
pathological gambling 3.3
drug addiction 3.3
compulsion 3.3
drug withdrawal 3.3
ISH 3.3
disabling disease 3.3
nerve lesion 3.3
Smith-Lemli-Opitz syndrome 3.3
Habituation 3.3
Sheehan's syndrome 3.3
separation anxiety 3.2
psychosis 3.2
LTD 3.2
GCT 3.2
suicide attempts 3.2
Beard 3.2
Tourette syndrome 3.2
suicide 3.1
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Symptom
Apneusis 9.0
Drugged 8.6
impaired motor coordination 6.5
startle reaction 6.2
hypothermia 5.9
Extrapyramidal symptoms 5.9
lightheadedness 5.5
despair 5.3
Decreased activity 5.0
adipsia 4.9
generalized pain 4.9
Involuntary Movement 4.8
disturbed balance 4.6
rundown 4.5
myoclonus 4.5
athetosis 4.4
retching 4.4
bradykinesia 4.1
twitching 4.1
muscle rigidity 4.0
catatonia 4.0
insomnia 3.7
Neuropathic pain 3.6
POA 3.4
hyperemesis gravidarum 3.4
analgesia 3.2
Sedation 3.1
dizziness 3.0
tremor 3.0
cerebellar ataxia 3.0
nausea 3.0
clonus 3.0
acute stress 2.9
agitation 2.8
torticollis 2.8
asthenia 2.7
incoordination 2.7
Depressive symptoms 2.5
chorea 2.4
dystonia 2.4
anorexia 2.4
hot flashes 2.4
urinary frequency 2.3
abnormal gait 2.3
hypercapnia 2.3
sleepiness 2.3
vomiting 2.3
nausea and vomiting 2.2
ataxia 2.2
hot flushes 2.2
masculinization 2.2
bitter taste 2.0
menopausal symptoms 1.8
alexithymia 1.7
seizures 1.7
acute pain 1.5
leg pain 1.5
constipation 1.5
blurred vision 1.5
polydipsia 1.4
pain 1.3
hopelessness 1.3
headache 1.3
hypotonia 1.0
cancer pain 0.9
syncope 0.9
spasticity 0.8
myalgia 0.8
cough 0.7
exhaustion 0.7
apathy 0.5
discomfort 0.3
anesthesia 0.3
distraction 0.3
fatigue 0.3
discomfort 0.2
paresthesia 0.2
diarrhea 0.1
hunger 0.0
lethargy 0.0
paresis -0.0
vertigo -0.3
angina -0.9
Ill -1.0
starvation -1.1
functional recovery -1.2
collapse -1.3
overweight -2.2
abdominal pain -2.4
Drug
Tandospirone citrate 12.5
Mazapertine succinate 12.5
Xaliproden 11.9
Flesinoxan 11.5
EMD 128130 10.9
SR 57746A 10.9
Flibanserin 10.7
Buspar 10.4
Bemesetron 10.2
MDL 11939 10.2
Cloperastine 9.9
Buspar 9.8
Serzone 9.7
Setoperone 9.7
Renzapride 9.7
Ritanserin 9.4
Bifeprunox 9.2
Tofisopam 8.9
Remeron 8.9
Ipecac syrup 8.9
Blonanserin 8.7
Uncaria hook 8.7
Desvenlafaxine succinate 8.3
Zotepine 8.1
Carisbamate 8.1
Zofran 8.0
Terguride 7.9
Mirtazapine 7.9
Pizotifen 7.8
Alprenolol 7.7
Epinastine 7.7
Zofran 7.6
Alaproclate 7.6
Paliperidone palmitate 7.6
7-Nitroindazole 7.6
Dexfenfluramine 7.5
Tryptophane 7.5
Diethylpropion 7.4
Tariquidar 7.4
DHT 7.3
DHT 7.2
Naftopidil 7.2
Alpidem 7.2
Tianeptine 7.2
Lisuride 7.0
Nicorette 6.9
Iloperidone 6.9
Rotigotine 6.8
Duloxetine 6.8
Compound 16 6.8
Trimipramine 6.7
Frovatriptan 6.7
Atipamezole 6.7
Reboxetine 6.5
Dihydroergotamine 6.5
Nicorette 6.3
Remoxipride 6.1
Portal 6.0
Compound 19 6.0
Seroquel 6.0
Domperidone 5.9
Scopolamine 5.8
ICI 5.8
Atropine sulfate 5.7
Prozac 5.5
Cantor 5.5
Clonidine 5.4
Sulpiride 5.3
Reserpine 5.1
Cisapride 5.1
Moclobemide 5.0
Agomelatine 5.0
PCP 4.7
Escitalopram 4.5
Compound 9 4.5
CDX 4.5
Isradipine 4.5
Nebivolol 4.4
Forskolin 4.3
Palmitoyl 4.3
Apomorphine 4.2
CDX 4.1
Diphenhydramine 4.0
Piracetam 4.0
Flunitrazepam 4.0
Felodipine 3.9
Atenolol 3.7
Timolol 3.7
APD 3.7
DEX 3.6
Oxaliplatin 3.6
CDP 3.6
Atropine 3.6
Emodin 3.6
MTC 3.5
Donepezil 3.4
CED 3.3
Emodin 3.3
Phentolamine 3.3
R1881 3.2
Pilocarpine 3.1
Kainic acid 3.1
DMI 3.0
Ringer's solution 2.6
Ethanol 2.5
TAK 2.5
CTX 2.5
Luteinizing 2.5
Nephron 2.4
Mutagen 2.3
Fentanyl 2.2
ETS 2.1
Meth 2.1
nitroglycerin 1.9
balanced salt solution 1.9
MgSO4 1.9
Bayer 1.9
VCR 1.9
9-THC 1.7
Histamine 1.6
Check 1.5
Frontal 1.5
L-tyrosine 1.3
caffeine 1.3
EE2 1.1
CaCl2 0.8
CaCl2 0.8
CaCl2 0.8
HCH 0.7
PCB 0.4
ENT 0.4
CAM -0.0
Bifidobacterium -0.0
Indomethacin -0.1
Cardiovasc -0.5
DNase I -0.5
citric acid -0.8
CSF -0.9
ascorbate -1.0
Gel -1.4
MAP -1.5
NADH -1.9
IFN-gamma -2.3
lysine -2.4
Monit -2.6
Dermatol -3.5
Enzyme
GTI 8.4
indole 2,3-dioxygenase 8.1
tryptophan hydroxylase 7.9
DMT 7.8
endo-N 6.6
PAT 6.5
aromatic L-amino acid decarboxylase 6.2
DOPA decarboxylase 6.1
hydroxyprostaglandin dehydrogenase 5.9
LDT 5.6
DSR 5.6
PWD 5.4
nucleoside diphosphokinase 5.1
monoamine oxidase 5.1
adenylate cyclase 5.1
PCP 4.7
SNO 3.9
CGT 3.7
DAT 3.5
aldehyde reductase 3.5
aldehyde reductase 3.5
aldehyde reductase 3.4
E-2 3.0
phospholipase C 2.8
BAT 2.8
tryptophan 2,3-dioxygenase 2.7
tyrosine hydroxylase 2.6
MPP 2.6
interstitial collagenase 2.6
DCF 2.5
CaMKII 2.5
CYP3A4 2.4
sorbitol dehydrogenase 2.4
ricin 2.4
GSK 2.3
phosphodiesterase 2.3
TSA 2.2
guanylate cyclase 2.2
cholinesterase 2.2
tryptase 2.0
dopamine beta-hydroxylase 2.0
protein kinase C 2.0
indoleamine 2,3-dioxygenase 2.0
aequorin 2.0
renin 1.9
NO synthase 1.9
CPT 1.8
aldose reductase 1.8
CPT 1.7
acetylcholinesterase 1.7
protein kinase 1.7
BAL 1.5
choline acetyltransferase 1.4
glutamate decarboxylase 1.4
P-glycoprotein 1.4
CPT 1.3
transcriptase 1.3
PKG 1.2
glutamine synthetase 1.2
myosin light chain kinase 1.1
phosphatidylinositol 3-kinase 1.0
lipoxygenase 1.0
cytochrome oxidase 1.0
carboxylesterase 0.9
tyrosinase 0.9
mitogen-activated protein kinase 0.9
HSD 0.7
MEK 0.7
NOS 0.6
ERK 0.6
enolase 0.6
AMPK 0.5
aldehyde dehydrogenase 0.4
aldehyde dehydrogenase 0.4
MDR 0.4
PAH 0.4
aldehyde dehydrogenase 0.4
ACE 0.3
chloramphenicol acetyltransferase 0.2
aldehyde dehydrogenase 0.1
CPR 0.1
phosphoinositide 3-kinase -0.0
caspase-3 -0.1
glyceraldehyde-3-phosphate dehydrogenase -0.2
aldehyde dehydrogenase -0.2
ACS -0.2
phospholipase A2 -0.3
urease -0.3
MAP -0.4
urease -0.4
luciferase -0.4
pepsin -0.6
RNA polymerase -0.6
elastase -0.7
alcohol dehydrogenase -0.7
reverse transcriptase -0.9
aspartate aminotransferase -0.9
focal adhesion kinase -0.9
tissue plasminogen activator -1.0
AMP-activated protein kinase -1.2
alanine aminotransferase -1.2
PARP -1.3
trypsin -1.3
proteasome -1.3
beta-galactosidase -1.4
alkaline phosphatase -1.5
RNase -1.5
thrombin -1.5
RNase -1.7
collagenase -1.7
lipase -1.7
ATPase -1.9
catalase -2.3
lactate dehydrogenase -2.4
Compound
N-Methyllaurotetanine 12.5
1H-benzo[f]isoindole-1,3(2H)-dione 12.5
4-fluoro-3-methylbenzoic acid 12.5
1-(3-(trifluoromethyl)phenyl)piperazine 12.5
UH-301 12.2
2-chloro-6-(1-piperazinyl)pyrazine 11.5
Alverine citrate 10.9
C6H8N2O2 10.9
cyclohexanecarboxamide 10.7
1-(3-chlorophenyl)piperazine 10.7
Buspirone 10.4
PAPP 10.3
MeODMT 10.2
SB 200646 10.2
1-(2-pyridinyl)piperazine 10.2
PAPP 10.1
Cephaeline 9.9
1,3-dihydro-2H-benzimidazole-2-thione 9.9
piperidine oxalate 9.9
cyclohexanecarbonyl chloride 9.9
1,3-dihydro-2H-benzimidazole-2-thione 9.9
1-phenylpiperazine 9.9
1-phenylpiperazine 9.9
1,3-dihydro-2H-benzimidazole-2-thione 9.9
1,3-dihydro-2H-benzimidazole-2-thione 9.9
Nemonapride 9.8
Pindolol 9.7
3-phenylquinoline 9.6
Spiperone 9.5
pyrrolo[1,2-a]quinoxaline 9.3
3-phenylquinoline 9.3
5-MeOT 9.3
Risperidone 9.2
Psilocin 9.2
mCPBG 9.1
1,2-benzisothiazol-3(2H)-one 1,1-dioxide 9.0
1,2-benzisothiazol-3(2H)-one 1,1-dioxide 9.0
1,2-benzisothiazol-3(2H)-one 1,1-dioxide 9.0
1,2-benzisothiazol-3(2H)-one 1,1-dioxide 9.0
Geissoschizine 9.0
Neu5Ac 8.9
4-Hydroxybiphenyl 8.9
Urapidil 8.9
5-HTP 8.9
5-HTP 8.9
1H-isoindole-1,3(2H)-dione 8.8
5-HT 8.8
2-azaspiro[4.4]nonane 8.8
THBP 8.7
Aripiprazole 8.6
Ketanserin 8.4
piperazine 8.4
5-Hydroxyindole 8.4
Indeloxazine 8.4
Echinocystic acid 8.4
2-Mercaptobenzimidazole 8.4
8-azaspiro[4.5]decane 8.4
2H-1,4-benzoxazin-3(4H)-one 8.4
ZMB 8.2
EEDQ 8.2
1H-indole-3-carboxylic acid 8.2
DAU 8.2
5-hydroxytryptophan 8.2
2-chloropyrimidine 8.2
Nefazodone 8.2
Penbutolol 8.1
DAU 8.1
Psilocybin 8.1
Idazoxan 8.0
Diethylpropion 8.0
Mirtazapine 8.0
Methysergide 8.0
8-azaspiro[4.5]decane-7,9-dione 8.0
1H-indole 7.9
dipropyl 7.9
1-benzylpiperazine 7.9
Ziprasidone 7.9
Fenfluramine 7.8
1-methyl-1H-indole 7.8
Phthalimide 7.8
DMT 7.8
CPP 7.7
DMT 7.6
1-benzylpiperazine 7.6
2-piperidinone 7.6
Xanomeline 7.5
Oleamide 7.5
LSD 7.5
5-HIAA 7.5
4-fluorobenzoic acid 7.4
Sumatriptan 7.4
Dihydroergotamine 7.4
Fluvoxamine 7.4
1,2,3,4-tetrahydronaphthalene 7.4
Benzylpiperazine 7.4
CPP 7.3
Ergotamine tartrate 7.3
imidazo[1,5-a]pyridine 7.3
Niguldipine 7.3
Trimethadione 7.3
Citalopram 7.2
HBr 7.2
Paroxetine 7.2
3-methoxybenzamide 7.2
Carteolol 7.1
Papaverine hydrochloride 7.1
Methylazoxymethanol 7.1
DHT 7.0
Naratriptan 7.0
1,2,3,6-tetrahydropyridine 7.0
1,3-benzodioxole 6.9
Granisetron 6.9
1,2,3,6-tetrahydropyridine 6.9
Cannabidiol 6.9
CPA 6.9
cyclohexanecarboxylic acid 6.9
cyclohexanecarboxylic acid 6.9
cyclohexanecarboxylic acid 6.9
1-azabicyclo[2.2.2]oct-3-yl 6.9
cyclohexanecarboxylic acid 6.9
cyclohexanecarboxylic acid 6.9
Clomipramine 6.9
hydroxyindoleacetic acid 6.8
decane 6.8
Ondansetron 6.8
MCPP 6.8
p-Chloroamphetamine 6.8
9H-xanthen-9-one 6.8
N-methylbenzamide 6.7
Loxapine 6.7
6-fluorotryptophan 6.7
Tryptamine 6.7
Zolmitriptan 6.6
2-methoxybenzamide 6.6
hexanedioic acid 6.6
PAT 6.6
Sodium saccharin 6.5
Imipramine 6.5
Imipramine 6.5
Kryptofix 2.2 6.5
9H-xanthen-9-one 6.5
1H-pyrrolo[2,3-b]pyridine 6.4
Venlafaxine 6.4
3,4-Methylenedioxymethamphetamine 6.4
piperidine-2-carboxylic acid 6.4
Phloroglucinol 6.4
Tranylcypromine 6.3
Tropisetron 6.3
MAOA 6.2
Phloroglucinol 6.2
DBB 6.2
Aniracetam 6.2
propionamide 6.2
propionamide 6.2
HN2 6.1
IDPN 6.1
Medroxyprogesterone 6.1
cephalotaxine 6.1
(+)-Amphetamine 6.1
Trazodone 6.1
more...