Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P06889 (
Mol
)
630,302
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Mol
Pharmacol 1979
Sep
PMID:Involvement of phenolic metabolites in the irreversible protein-binding of aromatic hydrocarbons: reactive metabolites of [14C]naphthalene and [14C]1-naphthol formed by rat liver microsomes. 11 95
In synchronous cultures of P-815 murine mastocytoma and of Chinese hamster ovary (CHO) cells, the relative contribution of exogenous thymidine to DNA synthesis was studied by comparing rates of (3H)thymidine incorporation with the rate of DNA synthesis as derived from incorporation of (3H)thymidine (10(-5) M) in the presence of amethopterin. In synchronous P-815 cultures, time-dependent variations of DNA synthesis rates were in close agreement with those of (3H)thymidine incorporation rates at concentrations of the precursor ranging from 5 x 10(-8) to 10(-5) M. Similarly, in synchronous CHO cell cultures prepared by two different methods, time-dependent changes in DNA synthesis rate were almost identical with those of the rate of incorporation of (3H)thymidine supplied at 5 x 10(-8) M. Thus, at a given thymidine concentration in the medium, the proportion of thymine residues in DNA that were derived from exogenous thymidine remained nearly constant, even though rates of cellular DNA synthesis underwent pronounced changes. This indicates that in the synchronous culture systems used, utilization of exogenous thymidine is efficiently adapted to changing rates of DNA synthesis.
Mol
Cell Biochem 1979
Sep
28
PMID:Adaptation of thymidine utilization to changing rates of DNA synthesis in the cell cycle. 11 96
Mol
Immunol 1979
Sep
PMID:Attachment of antigens and antibodies to fixed red cells: their use in rosette and haemagllutination tests: a comparison with fresh red cells. 11 60
Mol
Immunol 1979
Sep
PMID:Radioimmunoassay for detection of IgM domains. 11 61
Mol
Immunol 1979
Sep
PMID:Reaction between the isolated globular sub-units of the complement component C1q and IgG-complexes. 11 62
Mol
Pharmacol 1975
Sep
PMID:Covalent labeling of the digitalis-binding component of plasma membranes. 12 64
Mol
Pharmacol 1975
Sep
PMID:Structure-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. IV. Dissociation rate constants for complexes of the enzyme with cardiac oligodigitoxides. 12 65
Mol
Pharmacol 1975
Sep
PMID:Structure-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. V. Dissociation rate constants of digitoxin acetates. 12 66
J
Mol
Cell Cardiol 1975
Sep
PMID:Further observations on species-determined differences in the calcium-accumulating activity of cardiac microsomal fractions. 12 49
J
Mol
Cell Cardiol 1975
Sep
PMID:Intramitochondrial gylcogen deposits in hypertrophied human myocardium. 12 50
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>