Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P06889 (Mol)
 630,302 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)


J Mol Biol 1978 Sep 05
PMID:Crystallographic data on a complete kappa-type human Bence-Jones protein. 10 75


J Mol Biol 1978 Sep 15
PMID:Dominant constitutive mutations in malT, the positive regulator gene of the maltose regulon in Escherichia coli. 10 76

Transfer RNAAsp2delta was isolated from Drosophila melanogaster by affinity chromatography on concanavalin A-Sepharose. The tRNA was iodinated "in vitro" with Na [125I] and hybridized "in situ" to salivary gland chromosomes from Drosophila. Subsequent autoradiography allowed the localization of the genes for tRNAAsp2 to the left arm of the second chromosome in the regions 29 D and E.
Mol Gen Genet 1978 Sep 08
PMID:The localization of tRNAAsp2 genes from Drosophila melanogaster by "in situ" hybridization. 10 67

The characteristics of Bacillus subtilis dnaF, a mutation specifying a temperature sensitive phenotype, were examined to determine its relationship to polC, the gene specifying the structure of DNA polymerase III (pol III). Exposure of growing cells bearing dnaF to non-permissive temperature inhibited replicative DNA synthesis and specifically depressed the expression of pol III activity in crude extracts. Highly purified pol III derived from cells bearing dnaF was temperature.sensitive in its polymerase activity, indicating that dnaF is a specific, polC mutation which specifies a structurally altered enzyme.
Mol Gen Genet 1978 Sep 08
PMID:Bacillus subtilis dnaF: a mutation of the gene specifying the structure of DNA polymerase III. 10 68


Mol Pharmacol 1978 Sep
PMID:Trans-stilbene oxide: a selective inducer of rat liver epoxide hydratase. 10 69


Mol Cell Endocrinol 1978 Sep
PMID:Pineal removal or denervation: effects on hypothalamic PRF activity in the rat. 10 49


Mol Cell Endocrinol 1978 Sep
PMID:Studies on the role of calcium and cyclic nucleotides in the control of TSH secretion. 10 50

We have analyzed the RNA synthesized during spore germination in Bacillus subtilis. Early in germination there is little incorporation of [3H]uridine into RNA. A large increase in incorporation into RNA was found at 45--60 min into germination which was in part due to increases in the specific activity of the UTP pool. When corrected for specific activity changes, the instantaneous rate of RNA synthesis showed a seven to tenfold increase between 30 and 45 min of germination. Polyacrylamide gel electrophoresis studies showed that the RNA synthesized during germination appeared very similar to the RNA made during vegetative growth. DNA-RNA hybridization studies indicated that mRNA and rRNA were synthesized throughout germination. Their relative proportions remained constant and were very similar to the composition of RNA synthesized during vegetative growth.
Mol Gen Genet 1979 Sep
PMID:RNA synthesis during spore germination in Bacillus subtilis. 11 79


Mol Gen Genet 1979 Sep
PMID:Bacillus subtilis mutants dependent on streptomycin. 11 80

When plasmids carrying leucine genes of Bacillus subtilis 168 were isolated from a restriction and modification deficient (r-m-) strain and used for transformation of a restricting strain B. subtilis 168 leu recE4, the number of transformants was greatly reduced. Transformation of rec+ strain (transformation by integration of the donor DNA into the chromosome) with the plasmids was not affected irrespective of whether the recipient carried the r+ or r- phenotype. These results show that the plasmid-mediated transformation is subject to the host controlled restriction and suggest that r-m- strains should be used for construction of recombinant DNA molecules in B. subtilis 168.
Mol Gen Genet 1979 Sep
PMID:Restriction of plasmid-mediated transformation in Bacillus subtilis 168. 11 81


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