Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P06889 (Mol)
 630,302 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1. Some effects of sodium salicylate upon anaerobic glycolysis have been studied in normal human erythrocytes incubated for up to 6 h at 37 degrees C in autologous sera. 2. Both glucose consumption and lactate production were stimulated by concentrations of salicylate up to 60 mmol/l but at the highest concentration used (90 mmol/l) an initial stimulus was followed by inhibition of glycolysis. 3. Losses occurred of adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP) and adenosine 5'-phosphate(AMP)at higher concentrations of salicylate and there was a concomitant increase of inorganic phosphate. 4. Other phosphate esters underwent concentration changes at higher concentrations of salicylate that reflected inadequate concentrations of ATP for glycolysis. 5. The rates of sodium efflux from, and potassium influx into, erythrocytes were unaffected by the presence of salicylate at concentrations sufficient to stimulate glycolysis.
Clin Sci Mol Med 1975 Nov
PMID:Anaerobic glycolysis in normal human erythrocytes incubated in vitro with sodium salicylate. 0 Jan 70

1. We measured the minute ventilation and arterial blood catecholamine concentrations in four normal men standing and at two levels of moderate treadmill exercise breathing 14% oxygen or air. 2. Minute ventilation was significantly higher during hypoxic exercise than during normoxic exercise at an oxygen uptake of 1500 ml/min. 3. Arterial plasma noradrenaline during hypoxic exercise at an oxygen uptake of 1500 ml/min was significantly greater than at rest. 4. Arterial plasma noradrenaline during normoxic exercise at an oxygen uptake of 1500 ml/min was not elevated above the resting concentration. 5. The results are compatible with the suggestion that increased concentrations of arterial plasma noradrenaline contribute to the hypoxic potentiation of the respiratory response to moderate exercise.
Clin Sci Mol Med 1975 Nov
PMID:Arterial catecholamines in hypoxic exercise in man. 0 Jan 71


Contemp Top Mol Immunol 1975
PMID:Kinetics of antibody--hapten reactions. 0 Feb 9


Mol Cell Endocrinol 1975 Oct
PMID:Properties of urophysial proteins (urophysins) from the white sucker, Catostomus commersoni. 0 Feb 68


J Mol Biol 1975 Aug 25
PMID:Gelation of sickle hemoglobin. III. Nitrosyl hemoglobin. 0 May 9


J Mol Biol 1975 Aug 25
PMID:Interactions between cysteine residues as probes of protein conformation: the disulphide bond between Cys-14 and Cys-38 of the pancreatic trypsin inhibitor. 0 May 10


J Mol Biol 1975 Nov 05
PMID:A study of the histidine residues of human carbonic anhydrase C using 270 MHz proton magnetic resonance. 0 May 11


J Mol Biol 1975 Nov 15
PMID:The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0. 0 May 12


J Mol Biol 1975 Nov 15
PMID:Electrostatic side chain complementarity in collagen fibrils. 0 May 13

Experiments were carried out to define the kinetic parameters of the major phosphate transport processes of rat liver mitochondria, and to obtain information about the molecular properties of these systems.
Mol Cell Biochem 1975 Nov 14
PMID:Phosphate transport in rat liver mitochondria. Kinetics, inhibitor sensitivity, energy requirements, and labeled components. 0 Jun 9


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