Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05412 (c-Jun)
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Human Gene/Protein
ZNF394 protein 11.4
c-Jun 11.4
EIF3H protein 11.4
deleted in lung and esophageal cancer protein 1 11.4
polypeptide N-acetylgalactosaminyltransferase 5 11.4
ARP mRNA 11.4
transforming protein p21 11.4
ZNF394 11.4
protein tyrosine phosphatase PEP 11.4
WD repeat-containing protein 35 10.4
FLYWCH1 10.4
ARL6IP2 10.4
Advanced glycosylation end product-specific receptor 10.4
zinc finger protein 16 10.4
GIG4 10.4
Ras-related protein Rab-37 10.4
YTH domain containing 2 10.4
TLE4 protein 10.4
MAP kinase kinase 4 10.3
NESG1 10.1
signalosome subunit 2 10.1
JNK3 10.0
KIP3 10.0
MKK7 9.9
JNK2 9.9
transient receptor potential cation channel, subfamily M, member 8 9.9
transmembrane trafficking protein 9.9
C-FGR 9.9
TIP27 9.9
PLEKHO1 9.9
tetratricopeptide repeat domain 5 9.9
HEPIS 9.9
sclerostin domain containing 1 9.9
FLJ31139 9.9
EDRF1 9.9
ITGB4 protein 9.9
KLHL31 9.9
ZNF668 9.9
Cellular tumor antigen p53 9.9
RC3H2 9.9
JIP1 9.8
MKK4 9.7
vacuolar protein sorting 33B 9.6
JNK1 9.6
Sperm-associated antigen 9 9.6
ATF2 9.6
C6orf4 9.6
Activating transcription factor 2 9.5
activating transcription factor 2 9.5
presenilin-binding protein 9.4
ZNF16 9.4
Squamous cell carcinoma antigen 1 9.4
NLRR-3 9.4
PP2Czeta 9.4
ZNF418 9.4
Retinoid-related orphan receptor alpha 9.4
TNF receptor-associated factor 5 9.4
JNK-interacting protein 3 9.4
JSAP1 9.4
MyD118 9.4
MLK3 9.3
MAPKK6 9.3
MAPK8IP1 9.2
Mitogen-activated protein kinase kinase 4 9.2
mixed lineage kinase 3 9.2
cAMP response element-binding protein 1 9.1
MLK 9.1
rhomboid domain containing 1 9.1
MEK partner 1 9.1
protocadherin 17 9.1
nuclear associated protein 9.1
ZNF322A 9.1
mutant GSTP1 9.1
Jun activation domain binding protein 9.1
GTF2F1 9.1
fat3 9.1
CGREF1 9.1
G5B 9.1
ZNF545 9.1
GPX3 protein 9.1
more...
Disease
MRX47 9.9
Gastrointestinal motility disorder 9.9
OASF 9.3
infectious arthropathy 9.1
MRX30 8.9
Arbovirus infection 8.3
skin cancer, basal cell 8.3
DEFECT 8.0
JIP 7.8
MCPH2 7.7
FGD3 7.6
Invasive bladder cancer 7.4
allergic edema 7.4
Granular corneal dystrophy 7.2
melanoma stage 7.1
AD4 7.0
Xeroderma pigmentosum group C 6.8
Maternal diabetes mellitus 6.8
CEP 6.7
PanIN-1 6.7
Retinal damage 6.6
FGD1 6.4
PCP abuse 6.3
cHL 6.1
VES 6.1
Peritoneal fibrosis 6.0
Cervical radiculopathy 6.0
Eosinophilic meningitis 6.0
Reovirus infection 5.9
Ectopic ACTH syndrome 5.9
Neonatal encephalopathy 5.9
SPAR 5.9
PanIN-2 5.9
TAM 5.8
Viral encephalitis 5.8
FRA 5.8
androgen independent prostate cancer 5.6
Diabetic polyneuropathy 5.5
Liver regeneration 5.5
Niemann-Pick disease type A 5.5
CACA 5.5
photokeratitis 5.4
CTLN2 5.3
testicular dysfunction 5.2
Brachydactyly 5.2
CYLD 5.1
alcoholic cardiomyopathy 5.1
DMAC 5.1
CRD1 5.1
environmental carcinogenesis 5.0
AGS 5.0
White Spot 5.0
Epidermolysis bullosa simplex 5.0
LAD2 4.9
adult brain tumor 4.9
Oxygen toxicity 4.9
monocytic leukemia 4.9
Sendai virus infection 4.9
Dedifferentiation 4.9
Prostate tumor 4.8
neoplastic transformation 4.8
Blastocystis infection 4.8
CMD1 4.8
Androgen deficiency 4.8
Taybi 4.8
HRA 4.8
HEP 4.8
DSH 4.7
Dental fluorosis 4.7
Burkitt-like lymphoma 4.7
skin tumor 4.7
KRS 4.6
Thoracic aortic aneurysm 4.6
Chondrosarcoma 4.6
Chondrosarcoma 4.6
lgl 4.6
diabetic hyperglycemia 4.6
HOA 4.5
SBMA 4.4
Renal fibrosis 4.4
more...
Symptom
Somatic pain 7.0
Bladder distention 7.0
Ear swelling 5.5
skin damage 5.0
intention tremor 3.0
bladder pain 2.8
Neuropathic pain 2.6
hyperoxia 2.6
functional recovery 2.3
starvation 2.1
memory loss 1.9
acute stress 1.6
neurological disability 1.6
DNA marker 1.6
nasal congestion 1.3
seizures 1.1
chronic constipation 1.1
sore throat 1.0
despair 0.8
enuresis 0.8
exhaustion 0.7
hypothermia 0.7
incoordination 0.6
cachexia 0.6
hepatomegaly 0.5
chronic cough 0.5
twitching 0.4
collapse 0.4
chorea 0.4
bradykinesia 0.2
masculinization 0.1
dry eye 0.1
paraparesis 0.0
lethargy -0.0
HSA -0.1
ataxia -0.2
flushing -0.2
erythema -0.2
splenomegaly -0.2
thinning -0.4
acute pain -0.5
hypercapnia -0.5
cough -0.5
diarrhea -0.8
respiratory distress -0.8
shortness of breath -0.9
pain -1.0
paresis -1.1
tremor -1.1
spasticity -1.2
tinnitus -1.2
anorexia -1.3
analgesia -1.3
spasm -1.4
weakness -1.4
dystonia -1.6
distraction -1.8
low back pain -1.8
constipation -1.9
fatigue -1.9
back pain -2.1
overweight -2.2
anesthesia -2.3
acidity -2.4
vomiting -2.5
discomfort -3.0
discomfort -3.1
dyspnea -3.3
headache -3.3
abdominal pain -3.5
Drug
Loquat leaf 10.4
Asiasarum root 9.9
Platonin 7.5
Safingol 7.3
Phosphomycin 7.2
Benfotiamine 6.3
Olopatadine hydrochloride 6.3
Trifluoroethanol 6.2
Mevastatin 6.0
Benzofuran 5.9
Sivelestat 5.9
Crotonaldehyde 5.7
CMX 5.6
Butaprost 5.5
Batroxobin 5.5
Arsenic trioxide 5.4
Hyperforin 5.4
Sesame oil 5.4
Vesnarinone 5.2
Telbivudine 5.1
2-Methoxyestradiol 5.1
Dexrazoxane 5.0
PDGF B-chain 5.0
Zinc sulfate 4.9
Zinc sulfate 4.9
Emodin 4.9
MAP 4.8
Sodium benzoate 4.8
IL-11 4.8
Myricetin 4.8
Compound 16 4.7
NOV 4.7
Epigallocatechin 4.6
Ulinastatin 4.6
Romidepsin 4.6
Sesamol 4.6
CED 4.6
Emodin 4.6
Red ginseng 4.6
Plavix 4.5
Celebrex 4.5
p75 4.5
Iopromide 4.4
Kainic acid 4.4
Roflumilast 4.4
Roflumilast 4.4
Heme 4.4
Areca 4.4
Dihydrotestosterone 4.3
TAK 4.3
RBT 4.3
Gel 4.2
Sulphasalazine 4.2
Angiotensin II 4.2
Soybean oil 4.2
IFN-beta 4.1
Darbepoetin alfa 4.1
Bortezomib 4.1
Lovastatin 4.1
ADR 4.0
Gelatin 4.0
Bromelain 4.0
ETS 4.0
SNL 3.9
ROS 3.9
Cetrorelix 3.8
Doyle 3.8
Rosiglitazone 3.8
Pramipexole 3.8
Cilostazol 3.8
Flavopiridol 3.8
Olmesartan 3.7
Retinoic acid 3.7
Rolipram 3.7
Pramipexole 3.7
Verteporfin 3.7
Lenalidomide 3.7
Finasteride 3.7
TAT 3.7
DNase I 3.6
more...
Enzyme
MEKK1 8.2
cathepsin O 7.9
mitogen-activated protein kinase 7.2
steroid 11beta-hydroxylase 7.0
MEK 7.0
CEP 6.9
tubulin-tyrosine ligase 6.5
CEP 6.4
caspase-4 6.3
caspase-4 6.1
sulfiredoxin 6.0
granzyme K 6.0
IKK 6.0
interstitial collagenase 5.9
CYP8B1 5.9
proprotein convertase 1 5.9
CLK1 5.9
MAP 5.8
NQO2 5.8
caspase-9 5.6
phosphatidylinositol 3-kinase 5.6
NSY 5.6
phosphoinositide 5-phosphatase 5.6
caspase-3 5.5
caspase-8 5.5
gamma-glutamylcysteine synthetase 5.5
collagenase 3 5.5
histone-lysine N-methyltransferase 5.4
deoxyhypusine hydroxylase 5.4
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.4
MMP-3 5.4
protein kinase 5.4
10-formyltetrahydrofolate dehydrogenase 5.3
caspase-7 5.3
caspase-7 5.2
phosphoinositide 3-kinase 5.2
inositol 3-kinase 5.2
caspase-2 5.2
3-hydroxy-3-methylglutaryl-CoA lyase 5.2
glycine N-methyltransferase 5.1
caspase-2 5.1
PARP 5.1
caspase-6 5.1
ECH 5.0
matrix metalloproteinase 14 5.0
luciferase 5.0
collagenase 4.9
protein kinase C 4.9
caspase-6 4.9
neutral sphingomyelinase 4.9
ERK 4.8
protein phosphatase 2A 4.8
chloramphenicol acetyltransferase 4.8
HCS 4.8
MPP 4.7
GSK 4.7
glutathione synthetase 4.6
methionine sulfoxide reductase 4.5
sulfhydryl oxidase 4.5
CYP7A1 4.5
heme oxygenase 4.5
MMP 4.5
cysteine synthase 4.5
NADPH oxidase 4.5
NADPH oxidase 4.5
HOA 4.4
matrix metalloproteinase 9 4.4
farnesyltransferase 4.4
myosin light chain kinase 4.4
histone acetyltransferase 4.3
methionine adenosyltransferase 4.3
prolinase 4.3
sphingosine kinase 4.2
SLB 4.2
calpain 3 4.2
AMP-activated kinase 4.2
TACE 4.1
betaine-homocysteine methyltransferase 4.1
disulfide reductase 4.0
glutathione S-transferase 4.0
more...
Compound
2-(2,5-dimethoxyphenyl)acetamide 11.4
C28H44O3 10.4
C16H12O4 10.4
Onnamide 10.4
Isosamidin 10.4
11H-indeno[1,2-b]quinoxalin-11-one 10.2
N-(2-pyridinyl)benzamide 9.9
Longikaurin A 9.9
Sennoside B 9.9
Theasinensin A 9.1
Geniposidic acid 8.9
Humulone 8.9
ATF 8.7
Fosfomycin sodium 8.6
Asperuloside 8.6
Tylophorine 8.5
Asperuloside 8.4
Asperuloside 8.4
Cephalostatin 1 8.3
Sugiol 8.3
3-bromo-4,5-dihydroxybenzaldehyde 8.3
lup-20(29)-en-3-one 8.1
Obovatol 8.1
Tomentosin 8.1
Rubratoxin B 8.0
5-chloro-2-hydroxybenzamide 8.0
Butin 7.9
2,4-pyrimidinediamine 7.7
Anisomycin 7.7
C13H13NO3 7.6
Nonanal 7.6
Theaflavin 7.5
LNO2 7.5
Sangivamycin 7.5
delta12,14-PGJ2 7.5
Acacetin 7.4
Daphnetin 7.4
Triethylene glycol dimethacrylate 7.4
Echinocystic acid 7.4
Humulone 7.4
8-azaspiro[4.5]decane 7.4
estra-1,3,5(10)-triene-3,17-diol 7.3
Quercetagetin 7.3
Nobiletin 7.3
Raddeanin A 7.2
Eupafolin 7.2
Trimethyltin chloride 7.1
Butein 7.1
Taraxasterol 7.1
NS 1619 7.1
Carnosol 7.0
cholest-4-ene 7.0
Berbamine 6.9
Sennoside A 6.9
Benzyl isothiocyanate 6.9
3,4-D 6.7
Glyceollin 6.7
Glyceollin 6.7
SP-1 6.7
Ergosterol peroxide 6.7
Jatrorrhizine 6.7
Phorone 6.7
Ciclopirox olamine 6.6
Arctiin 6.6
Xylobiose 6.6
Phorone 6.6
Glycochenodeoxycholic acid 6.6
LY 294002 6.6
Eupatilin 6.6
Tanshinone 6.6
4-(methylsulfonyl)phenyl 6.5
RBA 6.5
2,5-dimethylpiperazine 6.5
2,5-dimethylpiperazine 6.5
Cafestol 6.4
Guggulsterone 6.4
Homocarnosine 6.4
4-methyl-1,2,3-thiadiazole 6.4
Merbarone 6.4
Wedelolactone 6.4
more...