Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P05412 (c-Jun)
11,453 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein c-Jun 11453 p38 2323 AP-1 2252 JNK 2153 Mol 1425 MAPK 1019 extracellular signal-regulated kinase 984 mitogen-activated protein 969 ERK1 858 Sep 789 caspase-3 749 ERK 737 cytokine 687 JNK1 671 tumor necrosis factor 593 p53 550 lipopolysaccharide 510 Bcl-2 459 p65 454 TNF 429 c-fos 413 p38 mitogen-activated protein kinase 405 IL-6 371 MEK 363 insulin 354 JNK2 336 MAP kinase 301 ATF 294 MKK4 272 cyclooxygenase-2 259 cytochrome c 243 inducible nitric oxide synthase 238 MEK1 231 extracellular signal-regulated kinase 1 220 matrix metalloproteinase 217 cyclin D1 208 collagen 208 c-Myc 206 AKT 204 p21 204 endoplasmic reticulum 202 CREB 201 TNF-alpha 194 phosphatase 193 phosphatidylinositol 3-kinase 192 leucine zipper 191 tyrosine kinase 189 ERK2 185 AP1 172 IL-8 171 p38 MAP kinase 169 Fas 166 interleukin-6 165 caspase-9 163 threonine 160 p50 157 proteasome 155 PI3K 155 LPS 155 caspase-8 152 MAP 152 AMP 151 epidermal growth factor 149 PARP 149 proto-oncogene 148 Sp1 148 TLR4 145 ATF2 144 MKK7 142 ATP 137 ubiquitin 135 Rho 132 MMP-9 132 MEKK1 132 p42 128 PKC 125 GSH 125 vascular endothelial growth factor 124 COX-2 124 JNK3 123 more...

Disease cancer 1643 tumor 1164 tumorigenesis 325 breast cancer 304 ischemia 285 carcinogenesis 282 hepatocellular carcinoma 233 diabetes 221 carcinoma 217 Alzheimer's disease 200 leukemia 192 tumor growth 173 obesity 157 prostate cancer 144 tumor progression 140 melanoma 139 atherosclerosis 138 MCF 128 GSH 125 Parkinson's disease 123 colon cancer 116 lung cancer 112 neuroblastoma 103 glioma 96 stroke 95 cerebral ischemia 88 adenocarcinoma 85 hypertension 83 squamous cell carcinoma 81 metastases 77 rheumatoid arthritis 76 colorectal cancer 75 ovarian cancer 64 type 2 diabetes 63 lymphoma 62 asthma 60 gastric cancer 58 retinoblastoma 58 virus infection 57 arthritis 57 B-cell lymphoma 55 osteosarcoma 54 multiple myeloma 54 heart failure 53 glioblastoma 52 Blocking 52 non-small cell lung cancer 52 pancreatic cancer 51 neoplastic transformation 51 pertussis 50 cervical cancer 49 skin cancer 48 sepsis 48 hyperglycemia 47 Epstein 47 sepsis 46 ATM 44 acute myeloid leukemia 44 osteoarthritis 44 infectious diseases 42 TAM 41 fatty liver 41 acute promyelocytic leukemia 40 HIV 40 hepatitis B 38 plaque 38 cardiovascular disease 37 liver cancer 36 psoriasis 36 pheochromocytoma 36 colitis 35 myocardial ischemia 34 depression 34 CEP 33 lung carcinoma 33 liver cancer 32 Infection 32 myocardial infarction 32 metabolic syndrome 31 pulmonary fibrosis 31 more...

Symptom seizures 63 pain 46 starvation 38 functional recovery 23 skin damage 18 collapse 14 diarrhea 12 hyperoxia 11 hypothermia 10 exhaustion 8 anesthesia 8 cough 6 weakness 5 ataxia 5 fatigue 5 memory loss 5 acute stress 5 analgesia 4 respiratory distress 4 erythema 4 splenomegaly 3 thinning 3 tremor 3 hepatomegaly 3 cachexia 3 Neuropathic pain 3 flushing 2 vomiting 2 lethargy 2 sore throat 2 anorexia 2 overweight 2 headache 2 hypercapnia 2 despair 1 bladder pain 1 Ear swelling 1 bradykinesia 1 acute pain 1 neurological disability 1 discomfort 1 twitching 1 spasticity 1 tinnitus 1 nasal congestion 1 chorea 1 paraparesis 1 Somatic pain 1 chronic constipation 1 discomfort 1 shortness of breath 1 back pain 1 constipation 1 chronic cough 1 acidity 1 HSA 1 incoordination 1 distraction 1 dry eye 1 DNA marker 1 masculinization 1 Bladder distention 1 dyspnea 1 dystonia 1 low back pain 1 intention tremor 1 abdominal pain 1 spasm 1 paresis 1 enuresis 1

Drug MAP 159 ROS 104 Gel 100 IL-2 82 IFN-gamma 71 Dermatol 57 lysine 54 DNase I 36 Angiotensin II 33 p75 31 CSF 30 vitamin E 25 Heme 23 ascorbate 23 Cardiovasc 21 Arsenic trioxide 20 IFN-beta 19 Glutathione 19 Retinoic acid 16 ETS 15 ICI 14 Ethanol 13 ADR 12 IL-11 11 TAT 11 caffeine 11 EE2 11 Taxol 10 Gelatin 10 Indomethacin 9 ETA 9 Bortezomib 9 Lovastatin 8 Asn 8 Nephron 8 Monit 8 uPA 7 Forskolin 7 G-CSF 7 Estrogens 7 TAK 7 Parkin 6 CTX 6 Simvastatin 6 Parkin 6 Sorafenib 6 Silica 6 Activin 5 DHT 5 Kainic acid 5 DHT 5 CED 5 CTX 5 Histamine 5 Emodin 5 GEO 5 Adriamycin 5 CTX 5 Biopolymers 5 Emodin 5 Portal 4 IL-1ra 4 Growth hormone 4 Glucagon 4 ZnO 4 Docetaxel 4 Rosiglitazone 4 PCP 4 Vitamin A 4 Etoposide 4 Epigallocatechin 4 Imatinib 4 Ginseng 4 Glycyrrhiza 4 Nitric Oxide 4 Growth hormone 4 CCL 4 Photofrin 3 Leaf 3 DEX 3 more...

Enzyme mitogen-activated protein kinase 5022 protein kinase 1212 ERK 955 MEK 840 caspase-3 596 protein kinase C 530 luciferase 430 focal adhesion kinase 222 collagenase 200 MEKK1 197 phosphatidylinositol 3-kinase 192 PARP 166 proteasome 158 MAP 153 catalase 153 superoxide dismutase 136 glutathione S-transferase 133 caspase-9 131 IKK 113 caspase-8 111 calcineurin 93 NO synthase 90 NADPH oxidase 90 NADPH oxidase 81 phosphoinositide 3-kinase 78 AMP-activated protein kinase 70 GSK 62 peroxidase 56 thrombin 54 phospholipase C 54 MMP-3 51 urokinase-type plasminogen activator 51 lactate dehydrogenase 50 chloramphenicol acetyltransferase 50 glutathione peroxidase 47 alanine aminotransferase 45 cdc2 44 alkaline phosphatase 43 AMPK 42 RNA polymerase 41 reverse transcriptase 35 heme oxygenase 34 MMP 34 tyrosine hydroxylase 34 caspase-1 33 CEP 33 CEP 33 ATPase 30 protein phosphatase 2A 30 P-glycoprotein 28 AMPK 25 aspartate aminotransferase 25 phospholipase A2 24 gamma-glutamylcysteine synthetase 23 NQO1 23 thymidine kinase 22 MIP 22 interstitial collagenase 21 ornithine decarboxylase 20 myosin light chain kinase 20 histone acetyltransferase 20 renin 19 APC 18 MPP 18 kinesin 18 matrix metalloproteinase 9 17 glutathione reductase 16 complex I 16 lipoxygenase 16 acetylcholinesterase 15 NOS 15 creatine kinase 14 acid phosphatase 14 RNase 14 xanthine oxidase 14 RNase 14 peroxiredoxin 14 topoisomerase 13 caspase-7 13 ACS 12 more...

Compound DNA 2017 NH2 1214 oxygen 894 Dec 827 acetate 467 TNF 429 tyrosine 382 nitric oxide 329 serine 322 calcium 321 glucose 298 MEK 294 ATF 294 cAMP 265 threonine 242 cysteine 201 hydrogen 162 MAP 153 AMP 153 water 152 sodium 152 Clin 138 ATP 137 GSH 133 GSH 133 N-acetylcysteine 130 MTT 125 MDA 112 H2O2 104 THP 104 THP 103 retinoic acid 102 TPA 99 TPA 99 glutamate 91 leucine 89 alanine 84 ethanol 83 PMA 82 PMA 81 arginine 78 phosphate 78 lysine 72 PGE 70 GTP 65 COS 60 dUTP 60 Insulin 59 zinc 58 Ang II 58 sulfate 51 ADP-ribose 50 cadmium 50 Asp 50 potassium 50 Curcumin 49 bromide 47 iodine 45 CAT 43 CAT 43 CAT 43 ADP 42 methionine 41 galactose 40 Cardiol 40 ADP 40 ADP 40 proline 39 nitrogen 39 iron 38 pyrrolidine 37 salt 36 Angiotensin II 35 boron 35 cGMP 34 pyrrolidine 34 Neuronal 32 DDP 31 NMDA 31 APAP 30 more...

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