Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P05412 (c-Jun)
11,453 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
c-Jun 11453
p38 2323
AP-1 2252
JNK 2153
Mol 1425
MAPK 1019
extracellular signal-regulated kinase 984
mitogen-activated protein 969
ERK1 858
Sep 789
caspase-3 749
ERK 737
cytokine 687
JNK1 671
tumor necrosis factor 593
p53 550
lipopolysaccharide 510
Bcl-2 459
p65 454
TNF 429
c-fos 413
p38 mitogen-activated protein kinase 405
IL-6 371
MEK 363
insulin 354
JNK2 336
MAP kinase 301
ATF 294
MKK4 272
cyclooxygenase-2 259
cytochrome c 243
inducible nitric oxide synthase 238
MEK1 231
extracellular signal-regulated kinase 1 220
matrix metalloproteinase 217
collagen 208
cyclin D1 208
c-Myc 206
p21 204
AKT 204
more...
Disease
cancer 1643
tumor 1164
tumorigenesis 325
breast cancer 304
ischemia 285
carcinogenesis 282
hepatocellular carcinoma 233
diabetes 221
carcinoma 217
Alzheimer's disease 200
leukemia 192
tumor growth 173
obesity 157
prostate cancer 144
tumor progression 140
melanoma 139
atherosclerosis 138
MCF 128
GSH 125
Parkinson's disease 123
colon cancer 116
lung cancer 112
neuroblastoma 103
glioma 96
stroke 95
cerebral ischemia 88
adenocarcinoma 85
hypertension 83
squamous cell carcinoma 81
metastases 77
rheumatoid arthritis 76
colorectal cancer 75
ovarian cancer 64
type 2 diabetes 63
lymphoma 62
asthma 60
gastric cancer 58
retinoblastoma 58
arthritis 57
virus infection 57
more...
Symptom
seizures 63
pain 46
starvation 38
functional recovery 23
skin damage 18
collapse 14
diarrhea 12
hyperoxia 11
hypothermia 10
anesthesia 8
exhaustion 8
cough 6
fatigue 5
memory loss 5
ataxia 5
weakness 5
acute stress 5
erythema 4
analgesia 4
respiratory distress 4
cachexia 3
Neuropathic pain 3
splenomegaly 3
thinning 3
tremor 3
hepatomegaly 3
vomiting 2
flushing 2
overweight 2
sore throat 2
anorexia 2
lethargy 2
headache 2
hypercapnia 2
masculinization 1
Ear swelling 1
acute pain 1
neurological disability 1
discomfort 1
twitching 1
more...
Drug
MAP 159
ROS 104
Gel 100
IL-2 82
IFN-gamma 71
Dermatol 57
lysine 54
DNase I 36
Angiotensin II 33
p75 31
CSF 30
vitamin E 25
ascorbate 23
Heme 23
Cardiovasc 21
Arsenic trioxide 20
IFN-beta 19
Glutathione 19
Retinoic acid 16
ETS 15
ICI 14
Ethanol 13
ADR 12
TAT 11
caffeine 11
EE2 11
IL-11 11
Gelatin 10
Taxol 10
Indomethacin 9
ETA 9
Bortezomib 9
Lovastatin 8
Asn 8
Nephron 8
Monit 8
Estrogens 7
uPA 7
TAK 7
Forskolin 7
more...
Enzyme
mitogen-activated protein kinase 5022
protein kinase 1212
ERK 955
MEK 840
caspase-3 596
protein kinase C 530
luciferase 430
focal adhesion kinase 222
collagenase 200
MEKK1 197
phosphatidylinositol 3-kinase 192
PARP 166
proteasome 158
catalase 153
MAP 153
superoxide dismutase 136
glutathione S-transferase 133
caspase-9 131
IKK 113
caspase-8 111
calcineurin 93
NADPH oxidase 90
NO synthase 90
NADPH oxidase 81
phosphoinositide 3-kinase 78
AMP-activated protein kinase 70
GSK 62
peroxidase 56
thrombin 54
phospholipase C 54
MMP-3 51
urokinase-type plasminogen activator 51
chloramphenicol acetyltransferase 50
lactate dehydrogenase 50
glutathione peroxidase 47
alanine aminotransferase 45
cdc2 44
alkaline phosphatase 43
AMPK 42
RNA polymerase 41
more...
Compound
DNA 2017
NH2 1214
oxygen 894
Dec 827
acetate 467
TNF 429
tyrosine 382
nitric oxide 329
serine 322
calcium 321
glucose 298
MEK 294
ATF 294
cAMP 265
threonine 242
cysteine 201
hydrogen 162
AMP 153
MAP 153
sodium 152
water 152
Clin 138
ATP 137
GSH 133
GSH 133
N-acetylcysteine 130
MTT 125
MDA 112
H2O2 104
THP 104
THP 103
retinoic acid 102
TPA 99
TPA 99
glutamate 91
leucine 89
alanine 84
ethanol 83
PMA 82
PMA 81
more...